Felipe Cava

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Emerging knowledge of regulatory roles of D-amino acids in bacteria
    Felipe Cava
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA 02115, USA
    Cell Mol Life Sci 68:817-31. 2011
  2. pmc Distinct pathways for modification of the bacterial cell wall by non-canonical D-amino acids
    Felipe Cava
    Department of Microbiology and Molecular Genetics, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School and HHMI, Boston, MA, USA
    EMBO J 30:3442-53. 2011
  3. pmc Cell separation in Vibrio cholerae is mediated by a single amidase whose action is modulated by two nonredundant activators
    Andrea Moll
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, USA Department of Microbiology and Immunobiology, Harvard Medical School and HHMI, Boston, Massachusetts, USA
    J Bacteriol 196:3937-48. 2014
  4. pmc Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae
    Tobias Dörr
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Mol Microbiol 89:949-62. 2013
  5. pmc D-amino acids govern stationary phase cell wall remodeling in bacteria
    Hubert Lam
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA 02115, USA
    Science 325:1552-5. 2009
  6. pmc A D, D-carboxypeptidase is required for Vibrio cholerae halotolerance
    Andrea Moll
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, MA, 02155, USA Department of Microbiology and Immunobiology, Harvard Medical School, HHMI, Boston, MA, 02155, USA
    Environ Microbiol 17:527-40. 2015
  7. pmc Differential requirement for PBP1a and PBP1b in in vivo and in vitro fitness of Vibrio cholerae
    Tobias Dörr
    Division of Infectious Diseases, Brigham and Women s Hospital and Department of Microbiology and Immunobiology, Harvard Medical School and HHMI, Boston, Massachusetts, USA
    Infect Immun 82:2115-24. 2014
  8. pmc A novel peptidoglycan binding protein crucial for PBP1A-mediated cell wall biogenesis in Vibrio cholerae
    Tobias Dörr
    Division of Infectious Diseases, Brigham and Women s Hospital and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
    PLoS Genet 10:e1004433. 2014

Collaborators

Detail Information

Publications8

  1. pmc Emerging knowledge of regulatory roles of D-amino acids in bacteria
    Felipe Cava
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA 02115, USA
    Cell Mol Life Sci 68:817-31. 2011
    ....
  2. pmc Distinct pathways for modification of the bacterial cell wall by non-canonical D-amino acids
    Felipe Cava
    Department of Microbiology and Molecular Genetics, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School and HHMI, Boston, MA, USA
    EMBO J 30:3442-53. 2011
    ....
  3. pmc Cell separation in Vibrio cholerae is mediated by a single amidase whose action is modulated by two nonredundant activators
    Andrea Moll
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, USA Department of Microbiology and Immunobiology, Harvard Medical School and HHMI, Boston, Massachusetts, USA
    J Bacteriol 196:3937-48. 2014
    ..coli and V. cholerae, they can be combined into diverse functional regulatory networks. ..
  4. pmc Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae
    Tobias Dörr
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Mol Microbiol 89:949-62. 2013
    ..ShyA's substrate-dependent activity may contribute to selection of cleavage sites in PG, whose implications for the process of side-wall growth are discussed. ..
  5. pmc D-amino acids govern stationary phase cell wall remodeling in bacteria
    Hubert Lam
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA 02115, USA
    Science 325:1552-5. 2009
    ..Thus, synthesis of D-amino acids may be a common strategy for bacteria to adapt to changing environmental conditions...
  6. pmc A D, D-carboxypeptidase is required for Vibrio cholerae halotolerance
    Andrea Moll
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, MA, 02155, USA Department of Microbiology and Immunobiology, Harvard Medical School, HHMI, Boston, MA, 02155, USA
    Environ Microbiol 17:527-40. 2015
    ..The basis for the dacA-1 mutant's halosensitivity is unknown; nonetheless, the mutant's survival in biochemically uncharacterized environments (such as the suckling mouse intestine) can be used as a reporter of low Na(+) content. ..
  7. pmc Differential requirement for PBP1a and PBP1b in in vivo and in vitro fitness of Vibrio cholerae
    Tobias Dörr
    Division of Infectious Diseases, Brigham and Women s Hospital and Department of Microbiology and Immunobiology, Harvard Medical School and HHMI, Boston, Massachusetts, USA
    Infect Immun 82:2115-24. 2014
    ..Thus, at least for V. cholerae PBP1a pathway mutants, the growth phase of the inoculum is a key modulator of infectivity. ..
  8. pmc A novel peptidoglycan binding protein crucial for PBP1A-mediated cell wall biogenesis in Vibrio cholerae
    Tobias Dörr
    Division of Infectious Diseases, Brigham and Women s Hospital and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
    PLoS Genet 10:e1004433. 2014
    ..cholerae can be overcome either by augmenting PG synthesis or by reducing PG degradation, thereby highlighting the importance of balancing these two processes for bacterial survival. ..