HANNAI CAMPOS

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc A case-control study of physical activity patterns and risk of non-fatal myocardial infarction
    Jian Gong
    Department of Community Health, Brown University, Providence, RI 02912, USA
    BMC Public Health 13:122. 2013
  2. pmc trans-fatty acid isomers in adipose tissue have divergent associations with adiposity in humans
    Liesbeth A Smit
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Lipids 45:693-700. 2010
  3. ncbi request reprint Siesta and the risk of coronary heart disease: results from a population-based, case-control study in Costa Rica
    H Campos
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Epidemiol 29:429-37. 2000
  4. ncbi request reprint Diurnal and acute patterns of postprandial apolipoprotein B-48 in VLDL, IDL, and LDL from normolipidemic humans
    Hannia Campos
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Room 1 201, Boston, MA 02115, USA
    Atherosclerosis 181:345-51. 2005
  5. pmc Alpha-linolenic acid and risk of nonfatal acute myocardial infarction
    Hannia Campos
    Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
    Circulation 118:339-45. 2008
  6. ncbi request reprint Adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction in Costa Rica
    Ana Baylin
    Department of Nutrition, Room 353A, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 107:1586-91. 2003
  7. ncbi request reprint Coffee consumption and risk of type 2 diabetes and heart disease
    Hannia Campos
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Nutr Rev 65:173-9. 2007
  8. ncbi request reprint Gene-diet interactions and plasma lipoproteins: role of apolipoprotein E and habitual saturated fat intake
    H Campos
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Genet Epidemiol 20:117-128. 2001
  9. ncbi request reprint Distinct patterns of lipoproteins with apoB defined by presence of apoE or apoC-III in hypercholesterolemia and hypertriglyceridemia
    H Campos
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Lipid Res 42:1239-49. 2001
  10. pmc A higher ratio of beans to white rice is associated with lower cardiometabolic risk factors in Costa Rican adults
    Josiemer Mattei
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 94:869-76. 2011

Research Grants

  1. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2000
  2. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2000
  3. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2001
  4. Identification of biomarkers of fatty acid intake
    Hannia Campos; Fiscal Year: 2002
  5. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2002
  6. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2003
  7. DIETARY FATTY ACIDS, PPAR ACTIVATED GENES, AND CHD
    HANNAI CAMPOS; Fiscal Year: 2003
  8. DIETARY FATTY ACIDS, PPAR ACTIVATED GENES, AND CHD
    HANNAI CAMPOS; Fiscal Year: 2004
  9. DIETARY FATTY ACIDS, PPAR ACTIVATED GENES, AND CHD
    HANNAI CAMPOS; Fiscal Year: 2005

Collaborators

Detail Information

Publications76

  1. pmc A case-control study of physical activity patterns and risk of non-fatal myocardial infarction
    Jian Gong
    Department of Community Health, Brown University, Providence, RI 02912, USA
    BMC Public Health 13:122. 2013
    ..We aimed to identify physical activity patterns that take into account combinations of physical activities and examine the association between derived physical activity patterns and risk of acute myocardial infarction (AMI)...
  2. pmc trans-fatty acid isomers in adipose tissue have divergent associations with adiposity in humans
    Liesbeth A Smit
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Lipids 45:693-700. 2010
    ..These isomer-specific associations are an interesting new finding. Other prospective and intervention studies are necessary to examine these relationships further...
  3. ncbi request reprint Siesta and the risk of coronary heart disease: results from a population-based, case-control study in Costa Rica
    H Campos
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Epidemiol 29:429-37. 2000
    ....
  4. ncbi request reprint Diurnal and acute patterns of postprandial apolipoprotein B-48 in VLDL, IDL, and LDL from normolipidemic humans
    Hannia Campos
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Room 1 201, Boston, MA 02115, USA
    Atherosclerosis 181:345-51. 2005
    ..Although small apoB-48 lipoproteins may be atherogenic remnant particles, their very low concentration may diminish their clinical significance...
  5. pmc Alpha-linolenic acid and risk of nonfatal acute myocardial infarction
    Hannia Campos
    Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
    Circulation 118:339-45. 2008
    ..Intake of long-chain n-3 fatty acids found in fish is low in many countries worldwide. alpha-Linolenic acid could be a viable cardioprotective alternative to these fatty acids in these countries...
  6. ncbi request reprint Adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction in Costa Rica
    Ana Baylin
    Department of Nutrition, Room 353A, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 107:1586-91. 2003
    ..Alpha-linolenic acid may protect against cardiovascular disease. We examined the association between adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction (MI) in a population-based case-control study in Costa Rica...
  7. ncbi request reprint Coffee consumption and risk of type 2 diabetes and heart disease
    Hannia Campos
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Nutr Rev 65:173-9. 2007
    ....
  8. ncbi request reprint Gene-diet interactions and plasma lipoproteins: role of apolipoprotein E and habitual saturated fat intake
    H Campos
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Genet Epidemiol 20:117-128. 2001
    ..05 mmol/L, P = 0.009). These data suggest that the APOE2 allele could modulate the effect of habitual saturated fat on VLDL cholesterol and HDL cholesterol in a population with an average habitual total fat intake of less than 30%...
  9. ncbi request reprint Distinct patterns of lipoproteins with apoB defined by presence of apoE or apoC-III in hypercholesterolemia and hypertriglyceridemia
    H Campos
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Lipid Res 42:1239-49. 2001
    ..Therefore, VLDL particles with apoC-III may play a central role in identifying the high risk of coronary heart disease in hypertriglyceridemia, but their substantial prevalence in normolipidemics may be of clinical significance as well...
  10. pmc A higher ratio of beans to white rice is associated with lower cardiometabolic risk factors in Costa Rican adults
    Josiemer Mattei
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 94:869-76. 2011
    ..Costa Ricans follow a staple dietary pattern that includes white rice and beans, yet the combined role of these foods on cardiometabolic risk factors has not been studied...
  11. ncbi request reprint Low-density lipoprotein size, pravastatin treatment, and coronary events
    H Campos
    Department of Nutrition, Bldg 2, Room 353A, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    JAMA 286:1468-74. 2001
    ..Animal models link large LDL to atherosclerosis. However, the strong association between small LDL and other risk factors, particularly triglyceride levels, impedes determining whether LDL size independently predicts CHD in humans...
  12. ncbi request reprint Adipose tissue biomarkers of fatty acid intake
    Ana Baylin
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:750-7. 2002
    ..Biomarkers can provide a more accurate measure of long-term intake than can dietary questionnaires...
  13. ncbi request reprint Blood concentrations of individual long-chain n-3 fatty acids and risk of nonfatal myocardial infarction
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 88:216-23. 2008
    ..Whereas dietary intake of long-chain n-3 fatty acids has been associated with risk of nonfatal myocardial infarction (MI), few studies have examined the relation for blood concentrations...
  14. ncbi request reprint The type of oil used for cooking is associated with the risk of nonfatal acute myocardial infarction in costa rica
    Edmond K Kabagambe
    Department of Nutrition, Harvard School of Public Health, Boston MA 02115, USA
    J Nutr 135:2674-9. 2005
    ..14; CI: 0.84-1.56). These data suggest that as currently used in Costa Rica, and most likely in many other developing countries, the replacement of palm oil with a polyunsaturated nonhydrogenated vegetable oil would reduce the risk of MI...
  15. ncbi request reprint Hypertriglyceridemia but not diabetes status is associated with VLDL containing apolipoprotein CIII in patients with coronary heart disease
    Sung Joon Lee
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 167:293-302. 2003
    ..Diabetes status per se does not appear to be associated with high concentrations of apoCIII-containing TG-rich lipoprotein particles, if the plasma TG levels are similar...
  16. ncbi request reprint Intake of trans fatty acids and low-density lipoprotein size in a Costa Rican population
    Mi Kyung Kim
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Metabolism 52:693-8. 2003
    ..44 A increase in LDL size (P =.004). In sum, it is possible that the effects of dietary factors, such as intake of trans FA on CHD are mediated through their effects on LDL size...
  17. ncbi request reprint LDL containing apolipoprotein CIII is an independent risk factor for coronary events in diabetic patients
    Sung Joon Lee
    Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
    Arterioscler Thromb Vasc Biol 23:853-8. 2003
    ..We hypothesized that these lipoproteins increase coronary disease risk in diabetic patients beyond that caused by standard lipid risk factors...
  18. ncbi request reprint Ala12 variant of the peroxisome proliferator-activated receptor-gamma gene (PPARG) is associated with higher polyunsaturated fat in adipose tissue and attenuates the protective effect of polyunsaturated fat intake on the risk of myocardial infarction
    Edward A Ruiz-Narváez
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 86:1238-42. 2007
    ..The Ala12 allele of the peroxisome proliferator-activated receptor-gamma gene (PPARG) decreases the lipolysis of triacylglycerols in adipose tissue, which results in the accumulation of fatty acids in adipocytes...
  19. ncbi request reprint Plasma carotenoids and tocopherols and risk of myocardial infarction in a low-risk population of US male physicians
    A Elisabeth Hak
    Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, 181 Longwood Ave, Boston, Mass 02115 5804, USA
    Circulation 108:802-7. 2003
    ..Increased intake of carotenoids and vitamin E may protect against myocardial infarction (MI). However, prospective data on blood levels of carotenoids other than beta-carotene and vitamin E (tocopherol) and risk of MI are sparse...
  20. ncbi request reprint Plasma and erythrocyte biomarkers of dairy fat intake and risk of ischemic heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 86:929-37. 2007
    ..The relation between dairy product intake and the risk of ischemic heart disease (IHD) remains controversial...
  21. ncbi request reprint Arachidonic acid in adipose tissue is associated with nonfatal acute myocardial infarction in the central valley of Costa Rica
    Ana Baylin
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 134:3095-9. 2004
    ..Better understanding of the metabolic factors that increase AA in adipose tissue is urgently needed...
  22. ncbi request reprint Assessment of a dietary questionnaire in cancer patients receiving cytotoxic chemotherapy
    Jeffrey A Meyerhardt
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 23:8453-60. 2005
    ..Although several comprehensive dietary questionnaires have been validated and calibrated in healthy populations, similar studies have not been performed among cancer patients...
  23. ncbi request reprint APOC3/A5 haplotypes, lipid levels, and risk of myocardial infarction in the Central Valley of Costa Rica
    Edward A Ruiz-Narváez
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Lipid Res 46:2605-13. 2005
    ..In summary, this study supports the hypothesis that haplotypes in the APOC3 gene but not in the APOA5 gene increase susceptibility to MI...
  24. ncbi request reprint Some dietary and adipose tissue carotenoids are associated with the risk of nonfatal acute myocardial infarction in Costa Rica
    Edmond Kato Kabagambe
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 135:1763-9. 2005
    ..The mechanism underlying the positive association between lutein + zeaxanthin and the risk of MI warrants investigation...
  25. ncbi request reprint Individual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake
    Ahmed El-Sohemy
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:172-9. 2002
    ..The ability of adipose tissue carotenoid concentrations to reflect dietary intake in population studies is unknown...
  26. ncbi request reprint Effect of the combination of methyltestosterone and esterified estrogens compared with esterified estrogens alone on apolipoprotein CIII and other apolipoproteins in very low density, low density, and high density lipoproteins in surgically postmenopausal
    Stephanie E Chiuve
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Clin Endocrinol Metab 89:2207-13. 2004
    ..Methyltestosterone may lower plasma triglycerides through a reduction in apoCIII...
  27. pmc Abdominal obesity and hyperglycemia mask the effect of a common APOC3 haplotype on the risk of myocardial infarction
    Edward A Ruiz-Narváez
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 87:1932-8. 2008
    ..Genetic variation in the insulin response element of the APOC3 promoter is associated with an increased risk of MI...
  28. ncbi request reprint Long-chain n-6 polyunsaturated fatty acids in breast milk decrease the risk of HIV transmission through breastfeeding
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 86:682-9. 2007
    ..Breastfeeding accounts for a sizable proportion of infant HIV infections. Some fatty acids (FAs) are potent immunomodulators with virucidal activity, and their primary source in breastfed children is breast milk...
  29. ncbi request reprint Effect of apolipoprotein E genotype and saturated fat intake on plasma lipids and myocardial infarction in the Central Valley of Costa Rica
    Yadong Yang
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Hum Biol 79:637-47. 2007
    ....
  30. ncbi request reprint A prospective study of trans-fatty acid levels in blood and risk of prostate cancer
    Jorge E Chavarro
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:95-101. 2008
    ..Previous studies suggest a positive association between markers of trans-fatty acid intake and prostate cancer. We therefore prospectively evaluated the association between blood trans-fatty acid levels and risk of prostate cancer...
  31. ncbi request reprint Evolutionary rate heterogeneity of Alu repeats upstream of the APOA5 gene: do they regulate APOA5 expression?
    Edward A Ruiz-Narváez
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J Hum Genet 53:247-53. 2008
    ..Some Alu sequences may have functional relevance on the regulation of the APOA5-gene expression...
  32. ncbi request reprint Frequent intake of tropical fruits that are rich in beta-cryptoxanthin is associated with higher plasma beta-cryptoxanthin concentrations in Costa Rican adolescents
    Michael S Irwig
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 132:3161-7. 2002
    ..Intakes of beta-cryptoxanthin and papaya, a tropical fruit frequently consumed in Latin America, were the best predictors of beta-cryptoxanthin concentrations in plasma...
  33. ncbi request reprint Plasma carotenoids, retinol, and tocopherols and risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:153-60. 2005
    ..Although the association was strongest for alpha-carotene, the high degree of collinearity among plasma carotenoids limits our ability to conclude that this association is specific to any individual carotenoid...
  34. ncbi request reprint Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer
    Megan N Hall
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 16:314-21. 2007
    ..Aspirin also inhibits the cyclooxygenase-2 enzyme and may share with n-3 fatty acids a potential mechanism to decrease the risk of colorectal cancer...
  35. pmc Associations of cord blood fatty acids with lymphocyte proliferation, IL-13, and IFN-gamma
    Diane R Gold
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Allergy Clin Immunol 117:931-8. 2006
    ..However, both n-3 eicosapentaenoic acid (EPA) and n-6 arachidonic acid (AA) are required for normal fetal development...
  36. ncbi request reprint High 18:2 trans-fatty acids in adipose tissue are associated with increased risk of nonfatal acute myocardial infarction in costa rican adults
    Ana Baylin
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Nutr 133:1186-91. 2003
    ..Because the use of hydrogenated oils is increasing worldwide, consumers should be aware of the harmful effects of products containing partially hydrogenated oils...
  37. ncbi request reprint Alcohol intake, drinking patterns, and risk of nonfatal acute myocardial infarction in Costa Rica
    Edmond K Kabagambe
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 82:1336-45. 2005
    ..Moderate alcohol consumption is associated with a lower risk of myocardial infarction (MI). Whether alcohol is truly protective or whether the amount, type, or pattern of intake is the most important is still under debate...
  38. pmc Trans-fatty acid levels in sperm are associated with sperm concentration among men from an infertility clinic
    Jorge E Chavarro
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Fertil Steril 95:1794-7. 2011
    ..Trans-fatty acids were present in human sperm and were related inversely to sperm concentration (r = -0.44)...
  39. ncbi request reprint Clinical review 163: Cardiovascular endocrinology: Low-density lipoprotein size and cardiovascular disease: a reappraisal
    Frank M Sacks
    Harvard School of Public Health, Department of Nutrition, Boston, Massachusetts 02115, USA
    J Clin Endocrinol Metab 88:4525-32. 2003
  40. pmc Dietary interventions that lower lipoproteins containing apolipoprotein C-III are more effective in whites than in blacks: results of the OmniHeart trial
    Jeremy D Furtado
    Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 92:714-22. 2010
    ..In blacks, the concentration of lipoproteins with apo C-III is unknown, and the response to dietary strategies that lower triglyceride and apo C-III has not been investigated..
  41. ncbi request reprint Comparison between plasma and erythrocyte fatty acid content as biomarkers of fatty acid intake in US women
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 86:74-81. 2007
    ..Erythrocyte fatty acids may be superior to plasma fatty acids for reflecting long-term fatty acid intake because of less sensitivity to recent intake and a slower turnover rate...
  42. ncbi request reprint Fasting whole blood as a biomarker of essential fatty acid intake in epidemiologic studies: comparison with adipose tissue and plasma
    Ana Baylin
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 162:373-81. 2005
    ..Thus, fasting whole blood could be the sample of choice in epidemiologic studies because of its ability to predict intake, its accessibility, and minimum sample processing...
  43. ncbi request reprint A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk
    Jorge E Chavarro
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1364-70. 2007
    ..Animal models suggest that n-3 fatty acids inhibit prostate cancer proliferation, whereas n-6 fatty acids promote it, but epidemiologic studies do not uniformly support these findings...
  44. pmc Reproducibility of plasma and urine biomarkers among premenopausal and postmenopausal women from the Nurses' Health Studies
    Joanne Kotsopoulos
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:938-46. 2010
    ..Temporal variability of biomarkers should be evaluated before their use in epidemiologic studies...
  45. ncbi request reprint Blood levels of long-chain n-3 fatty acids and the risk of sudden death
    Christine M Albert
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    N Engl J Med 346:1113-8. 2002
    ..Whether long-chain n-3 fatty acids are also associated with the risk of sudden death in those without a history of cardiovascular disease is unknown...
  46. pmc Effect of protein, unsaturated fat, and carbohydrate intakes on plasma apolipoprotein B and VLDL and LDL containing apolipoprotein C-III: results from the OmniHeart Trial
    Jeremy D Furtado
    Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 87:1623-30. 2008
    ..Dietary intake affects lipoprotein concentration and composition related to those apolipoproteins...
  47. pmc Conjugated linoleic acid in adipose tissue and risk of myocardial infarction
    Liesbeth A Smit
    Department of Nutrition Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 92:34-40. 2010
    ..Pasture-grazing dairy cows have more CLA in their milk than do grain-fed cows. Some animal models have reported beneficial effects of CLA on atherosclerosis...
  48. ncbi request reprint Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy
    Marc S Sabatine
    TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arterioscler Thromb Vasc Biol 28:562-7. 2008
    ..The purpose of this study was to investigate the association between the Ala227Pro polymorphism in the ADAMTS1 metalloproteinase gene and coronary heart disease and benefit from statin therapy in 2 independent cohorts...
  49. ncbi request reprint West African and Amerindian ancestry and risk of myocardial infarction and metabolic syndrome in the Central Valley population of Costa Rica
    Edward A Ruiz-Narváez
    Slone Epidemiology Center, Boston University, Boston, MA, USA
    Hum Genet 127:629-38. 2010
    ..20 (1.01, 1.42). These results show that the high variability of admixture proportions in the Central Valley population offers a unique opportunity to uncover the genetic basis of ethnic differences on the risk of disease...
  50. pmc Adipose tissue arachidonic acid and the metabolic syndrome in Costa Rican adults
    Eric S Williams
    Department of Nutrition, Room 1 201, Harvard School of Public Health, Boston, MA 02115, USA
    Clin Nutr 26:474-82. 2007
    ..We examined the association between adipose tissue arachidonic acid and the metabolic syndrome in Costa Rica, a country in which the metabolic syndrome is highly prevalent...
  51. ncbi request reprint The use of fatty acid biomarkers to reflect dietary intake
    Ana Baylin
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Curr Opin Lipidol 17:22-7. 2006
    ..This review compares fatty acid biomarkers to assess compliance in dietary intervention trials with their application in epidemiological studies...
  52. ncbi request reprint A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 115:1858-65. 2007
    ..We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women...
  53. ncbi request reprint Decreased consumption of dried mature beans is positively associated with urbanization and nonfatal acute myocardial infarction
    Edmond K Kabagambe
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 135:1770-5. 2005
    ..No additional protection was observed at intakes > 1 serving/d. These findings are timely given the trend toward increased obesity, cardiovascular disease, and a reduction in the intake of beans in Latin American countries...
  54. ncbi request reprint Comparison of dietary intakes of micro- and macronutrients in rural, suburban and urban populations in Costa Rica
    Edmond K Kabagambe
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Public Health Nutr 5:835-42. 2002
    ..To compare, along with behavioural habits, the potential atherogenicity of diets in rural and urban areas in Costa Rica...
  55. ncbi request reprint Genetic variants of the lipoprotein lipase gene and myocardial infarction in the Central Valley of Costa Rica
    Yadong Yang
    Department of Nutrition, Harvard University School of Public Health, Boston, MA, USA
    J Lipid Res 45:2106-9. 2004
    ..The X447 mutant allele of the LPL gene may protect from MI risk, although this effect is small...
  56. ncbi request reprint Prospective study of plasma carotenoids and tocopherols in relation to risk of ischemic stroke
    A Elisabeth Hak
    Department of Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Stroke 35:1584-8. 2004
    ..Intake of fruits and vegetables has been related to lower risk of ischemic stroke, but nutrients responsible for this apparent benefit remain ill-defined. Tocopherols (vitamin E) have also been proposed to be protective...
  57. ncbi request reprint Costa Rican adolescents have a deleterious nutritional profile as compared to adults in terms of lower dietary and plasma concentrations of antioxidant micronutrients
    Edmond K Kabagambe
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Am Coll Nutr 24:122-8. 2005
    ....
  58. ncbi request reprint The relation between trans fatty acid levels and increased risk of myocardial infarction does not hold at lower levels of trans fatty acids in the Costa Rican food supply
    URIYOAN COLON-RAMOS
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Nutr 136:2887-92. 2006
    ..The public health sector of Costa Rica should regulate food labeling and content to ensure very low levels of TFA intake...
  59. ncbi request reprint B vitamins and plasma homocysteine concentrations in an urban and rural area of Costa Rica
    Mi Kyung Kim
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Am Coll Nutr 22:224-31. 2003
    ..Plasma folate and vitamin B(12) concentrations were measured in women...
  60. ncbi request reprint Dietary and adipose tissue gamma-tocopherol and risk of myocardial infarction
    Ahmed El-Sohemy
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Epidemiology 13:216-23. 2002
    ..Gamma-tocopherol, the most abundant form of dietary vitamin E, may lower the risk of coronary heart disease...
  61. ncbi request reprint Interaction between the APOC3 gene promoter polymorphisms, saturated fat intake and plasma lipoproteins
    Sherine Brown
    Department of Nutrition, Blg 2, Room 353A, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 170:307-13. 2003
    ..To test the hypothesis that APOC3 gene polymorphisms modulate the effect of saturated fat (SAT) intake on plasma lipoproteins and LDL size...
  62. pmc Genetic risk score and risk of myocardial infarction in Hispanics
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 123:374-80. 2011
    ..This study evaluated whether genetic markers previously identified in whites are associated with nonfatal acute myocardial infarction (MI) in Hispanics...
  63. ncbi request reprint Transmission disequilibrium test (TDT) for case-control studies
    Edward A Ruiz-Narváez
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Eur J Hum Genet 12:105-14. 2004
    ..In sum, this study describes a novel procedure that can be used to identify the transmission of disease susceptibility markers in population-based studies...
  64. ncbi request reprint Saturated and cis- and trans-unsaturated fatty acids intake in rural and urban Costa Rican adolescents
    Rafael Monge-Rojas
    Costa Rican Institute for Research and Education on Nutrition and Health INCIENSA, Ministry of Health, Apartado 4 2250, Tres Rios, Costa Rica
    J Am Coll Nutr 24:286-93. 2005
    ....
  65. ncbi request reprint Socio-economic status and health awareness are associated with choice of cooking oil in Costa Rica
    URIYOAN COLON-RAMOS
    National Cancer Institute, 6130 Executive Boulevard, Bethesda, MD 20892, USA
    Public Health Nutr 10:1214-22. 2007
    ..To examine the socio-economic and lifestyle determinants of cooking oil choice in Costa Rica during the last decade (1994-2004)...
  66. ncbi request reprint Polyunsaturated fatty acids, inflammation, and cardiovascular disease: time to widen our view of the mechanisms
    Frank M Sacks
    J Clin Endocrinol Metab 91:398-400. 2006
  67. ncbi request reprint Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption
    Marilyn C Cornelis
    Department of Nutritional Sciences, University of Toronto, Canada
    Am J Clin Nutr 86:240-4. 2007
    ..Caffeine is the most widely consumed stimulant in the world, and individual differences in response to its stimulating effects may explain some of the variability in caffeine consumption within a population...
  68. ncbi request reprint Microsomal epoxide hydrolase genotype and risk of myocardial infarction
    Marilyn C Cornelis
    Department of Nutritional Sciences, University of Toronto, Room 350, 150 College St, M5S 3E2, Toronto, ON, Canada
    Arch Toxicol 81:641-5. 2007
    ..95 (0.81-1.11) for individuals with the HR genotype and 1.18 (0.79-1.76) for those with the RR genotype. These results suggest that EPHX1 does not play a significant role in the development of CHD...
  69. ncbi request reprint GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction
    Marilyn C Cornelis
    Department of Nutritional Sciences, University of Toronto, Canada
    Am J Clin Nutr 86:752-8. 2007
    ..Isothiocyanates induce glutathione S-transferases (GSTs), polymorphic genes that code for enzymes that conjugate isothiocyanates, as well as mutagens and reactive oxygen species, to make them more readily excretable...
  70. ncbi request reprint Nonfatal acute myocardial infarction in Costa Rica: modifiable risk factors, population-attributable risks, and adherence to dietary guidelines
    Edmond K Kabagambe
    Department of Epidemiology, University of Alabama at Birmingham, School of Public Health, 1665 University Blvd, Birmingham, AL 35294 0022, USA
    Circulation 115:1075-81. 2007
    ..Cardiovascular disease, including myocardial infarction (MI), is increasing in developing countries. Knowledge of risk factors and their impact on the population could offer insights into primary prevention...
  71. ncbi request reprint alpha-Linolenic acid, Delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction
    Ana Baylin
    Department of Community Health, Brown University, Providence, RI, USA
    Am J Clin Nutr 85:554-60. 2007
    ..Delta(6)-Desaturase (FADS2) is the rate-limiting step in the polyunsaturated fatty acid (PUFA) biosynthetic pathway...
  72. ncbi request reprint Transient exposure to coffee as a trigger of a first nonfatal myocardial infarction
    Ana Baylin
    Department of Community Health, Brown University, Providence, RI 02912, USA
    Epidemiology 17:506-11. 2006
    ..We hypothesize that coffee in the presence of predisposing factors can induce a cascade of events that, through sympathetic nervous activation, can induce the onset of myocardial infarction...
  73. ncbi request reprint Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials
    Olga A Iakoubova
    Celera, Inc, Alameda, California 94502, USA
    J Am Coll Cardiol 51:435-43. 2008
    ....
  74. ncbi request reprint Coffee, CYP1A2 genotype, and risk of myocardial infarction
    Marilyn C Cornelis
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    JAMA 295:1135-41. 2006
    ..Individuals who are homozygous for the CYP1A2*1A allele are "rapid" caffeine metabolizers, whereas carriers of the variant CYP1A2*1F are "slow" caffeine metabolizers...
  75. pmc Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction
    Hooman Allayee
    Department of Preventive Medicine and the Institute for Genetic Medicine, The University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9075, USA
    Am J Clin Nutr 88:934-40. 2008
    ..We previously reported that variants of a 5-LO promoter repeat polymorphism were associated with carotid atherosclerosis in humans, an effect that was exacerbated by high dietary AA but mitigated by high dietary n-3 fatty acids...
  76. ncbi request reprint Asp92Asn polymorphism in the myeloid IgA Fc receptor is associated with myocardial infarction in two disparate populations: CARE and WOSCOPS
    Olga A Iakoubova
    Celera Inc, 1401 Harbor Bay Parkway, Alameda, CA 94502, USA
    Arterioscler Thromb Vasc Biol 26:2763-8. 2006
    ..Because the myeloid IgA Fc receptor encoded by FCAR mediates inflammation, we hypothesized that the FCAR Asp92Asn polymorphism is associated with risk of MI and that this risk would be modified by pravastatin...

Research Grants9

  1. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2000
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  2. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2000
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  3. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2001
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  4. Identification of biomarkers of fatty acid intake
    Hannia Campos; Fiscal Year: 2002
    ..abstract_text> ..
  5. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2002
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  6. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2003
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  7. DIETARY FATTY ACIDS, PPAR ACTIVATED GENES, AND CHD
    HANNAI CAMPOS; Fiscal Year: 2003
    ..Because polyunsaturated FAs are important as activators of PPARs and their capacity to regulate gene expression at the level of transcription, this metabolic system is a suitable candidate for the proposed study. ..
  8. DIETARY FATTY ACIDS, PPAR ACTIVATED GENES, AND CHD
    HANNAI CAMPOS; Fiscal Year: 2004
    ..Because polyunsaturated FAs are important as activators of PPARs and their capacity to regulate gene expression at the level of transcription, this metabolic system is a suitable candidate for the proposed study. ..
  9. DIETARY FATTY ACIDS, PPAR ACTIVATED GENES, AND CHD
    HANNAI CAMPOS; Fiscal Year: 2005
    ..Because polyunsaturated FAs are important as activators of PPARs and their capacity to regulate gene expression at the level of transcription, this metabolic system is a suitable candidate for the proposed study. ..