Hyang Min Byun
Affiliation: Harvard University
Byun H, Benachour N, Zalko D, Frisardi M, Colicino E, Takser L, et al
. Epigenetic effects of low perinatal doses of flame retardant BDE-47 on mitochondrial and nuclear genes in rat offspring. Toxicology. 2015;328:152-9 pubmed publisher
..23%, p=0.02). Decreased nuclear 5mC was observed in Bdnf and Nr3c1 in BDE-47 exposed rats. However, we did not observe significant effects of PBDE toxicity on DNA methylation patterns for the majority of genes in the brain. ..
Byun H, Barrow T. Analysis of pollutant-induced changes in mitochondrial DNA methylation. Methods Mol Biol. 2015;1265:271-83 pubmed publisher
..In this chapter, we describe a protocol for the isolation of mitochondrial DNA from peripheral blood samples and the analysis of 5-methylcytosine content by bisulfite pyrosequencing. ..
Bollati V, Favero C, Albetti B, Tarantini L, Moroni A, Byun H, et al
. Nutrients intake is associated with DNA methylation of candidate inflammatory genes in a population of obese subjects. Nutrients. 2014;6:4625-39 pubmed publisher
..012), Î²-carotene (Î² = -0.332, p = 0.045), carotenoids (Î² = -0.331, p = 0.015) and retinol (Î² = -0.360, p = 0.008). These results suggest a complex relationship among nutrient intake, oxidative stress and DNA methylation. ..
Byun H, Nordio F, Coull B, Tarantini L, Hou L, Bonzini M, et al
. Temporal stability of epigenetic markers: sequence characteristics and predictors of short-term DNA methylation variations. PLoS ONE. 2012;7:e39220 pubmed publisher
..The degree of short-term DNA methylation stability is marker-dependent and associated with sequence characteristics and methylation levels. ..
Byun H, Panni T, Motta V, Hou L, Nordio F, Apostoli P, et al
. Effects of airborne pollutants on mitochondrial DNA methylation. Part Fibre Toxicol. 2013;10:18 pubmed publisher
..Our results suggest that locus-specific mtDNA methylation is correlated to selected exposures and mtDNA damage. Larger studies are needed to validate our observations. ..