Research Topics
| Atul ButteSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Reproducibility of gene expression across generations of Affymetrix microarraysAshish Nimgaonkar
Informatics Program, Children s Hospital, Harvard Medical School, Boston, MA, USA
BMC Bioinformatics 4:27. 2003..In this study the reproducibility of gene expression levels across two generations of Affymetrix GeneChips (HuGeneFL and HG-U95A) was measured...
Quantifying the relationship between co-expression, co-regulation and gene functionDominic J Allocco
Informatics Program, Children s Hospital, Boston, MA, USA
BMC Bioinformatics 5:18. 2004....
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networksA J Butte
Children s Hospital Informatics Program and Division of Endocrinology, Department of Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 97:12182-6. 2000..We discuss the advantages of this methodology over alternative approaches, such as phylogenetic-type tree clustering and self-organizing maps...
Comparing the similarity of time-series gene expression using signal processing metricsA J Butte
Children s Hospital Informatics Program, 300 Longwood Avenue, Boston, Massachusetts 02115, USA
J Biomed Inform 34:396-405. 2001..Two of these were known in the biomedical literature and may have been missed using correlation coefficients. Digital signal processing tools can be embedded and enhance existing clustering algorithms...
The use and analysis of microarray dataAtul Butte
Children s Hospital Informatics Program and Division of Endocrinology, Children s Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA
Nat Rev Drug Discov 1:951-60. 2002..This article reviews the different ways to analyse large sets of microarray data, including the questions that can be asked and the challenges in interpreting the measurements...
Strict interpretation of vaccination guidelines with computerized algorithms and improper timing of administered dosesA J Butte
Division of Endocrinology, Children s Hospital, Boston, MA 02115, USA
Pediatr Infect Dis J 20:561-5. 2001..Frequently changing immunization recommendations may lead to incorrectly administered doses...
Data-driven methods to discover molecular determinants of serious adverse drug eventsA P Chiang
Department of Medicine, Stanford Center for Biomedical Informatics, Stanford University School of Medicine, Stanford, California, USA
Clin Pharmacol Ther 85:259-68. 2009..We also describe recent examples of how bioinformatics methods coupled with data repositories can advance the science of SADRs...
