Jeffrey S Brown

Summary

Affiliation: Harvard Medical School and Harvard Pilgrim Health Care
Country: USA

Publications

  1. ncbi request reprint Active influenza vaccine safety surveillance: potential within a healthcare claims environment
    Jeffrey S Brown
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Med Care 47:1251-7. 2009
  2. ncbi request reprint Distributed health data networks: a practical and preferred approach to multi-institutional evaluations of comparative effectiveness, safety, and quality of care
    Jeffrey S Brown
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Med Care 48:S45-51. 2010
  3. ncbi request reprint Early detection of adverse drug events within population-based health networks: application of sequential testing methods
    Jeffrey S Brown
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 16:1275-84. 2007
  4. ncbi request reprint Early adverse drug event signal detection within population-based health networks using sequential methods: key methodologic considerations
    Jeffrey S Brown
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 18:226-34. 2009
  5. doi request reprint Drug safety data mining with a tree-based scan statistic
    Martin Kulldorff
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 22:517-23. 2013
  6. pmc Near real-time adverse drug reaction surveillance within population-based health networks: methodology considerations for data accrual
    Taliser R Avery
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:488-95. 2013
  7. doi request reprint Outpatient urticaria diagnosis codes have limited predictive value for same-day influenza vaccine adverse event detection
    Kristen M Moore
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
    J Clin Epidemiol 63:407-11. 2010
  8. doi request reprint Risk of Guillain-Barré syndrome after meningococcal conjugate vaccination
    Priscilla Velentgas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 21:1350-8. 2012
  9. ncbi request reprint A distributed research network model for post-marketing safety studies: the Meningococcal Vaccine Study
    Priscilla Velentgas
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 17:1226-34. 2008
  10. ncbi request reprint Potential population-based electronic data sources for rapid pandemic influenza vaccine adverse event detection: a survey of health plans
    Kristen M Moore
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 17:1137-41. 2008

Detail Information

Publications21

  1. ncbi request reprint Active influenza vaccine safety surveillance: potential within a healthcare claims environment
    Jeffrey S Brown
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Med Care 47:1251-7. 2009
    ..Rapid safety assessment of novel vaccines, especially those targeted against pandemic influenza, is a public health priority...
  2. ncbi request reprint Distributed health data networks: a practical and preferred approach to multi-institutional evaluations of comparative effectiveness, safety, and quality of care
    Jeffrey S Brown
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Med Care 48:S45-51. 2010
    ....
  3. ncbi request reprint Early detection of adverse drug events within population-based health networks: application of sequential testing methods
    Jeffrey S Brown
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 16:1275-84. 2007
    ....
  4. ncbi request reprint Early adverse drug event signal detection within population-based health networks using sequential methods: key methodologic considerations
    Jeffrey S Brown
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 18:226-34. 2009
    ..Our objective was to expand our previous signal detection work by investigating the effect on signal detection of alternative study specifications...
  5. doi request reprint Drug safety data mining with a tree-based scan statistic
    Martin Kulldorff
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 22:517-23. 2013
    ..This methodological paper evaluates the tree-based scan statistic data mining method to enhance drug safety surveillance...
  6. pmc Near real-time adverse drug reaction surveillance within population-based health networks: methodology considerations for data accrual
    Taliser R Avery
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:488-95. 2013
    ..This study describes practical considerations for implementation of near real-time medical product safety surveillance in a distributed health data network...
  7. doi request reprint Outpatient urticaria diagnosis codes have limited predictive value for same-day influenza vaccine adverse event detection
    Kristen M Moore
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
    J Clin Epidemiol 63:407-11. 2010
    ..To assess the predictive value of claims-based outpatient urticaria diagnosis codes to identify potential vaccine-related adverse events (AEs) when recorded on the same day as influenza vaccination...
  8. doi request reprint Risk of Guillain-Barré syndrome after meningococcal conjugate vaccination
    Priscilla Velentgas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 21:1350-8. 2012
    ..We conducted a study to assess the risk of GBS after MCV4 vaccination using health plan administrative and claims data together with the review of primary medical records of potential cases...
  9. ncbi request reprint A distributed research network model for post-marketing safety studies: the Meningococcal Vaccine Study
    Priscilla Velentgas
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 17:1226-34. 2008
    ..Implementation has addressed several issues relevant to creation of a large scale post-marketing drug safety surveillance system envisioned by the FDA's Sentinel Initiative...
  10. ncbi request reprint Potential population-based electronic data sources for rapid pandemic influenza vaccine adverse event detection: a survey of health plans
    Kristen M Moore
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 17:1137-41. 2008
    ..Many public and private health plans and payers have such information...
  11. ncbi request reprint The U.S. Food and Drug Administration's Mini-Sentinel program: status and direction
    Richard Platt
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 21:1-8. 2012
    ....
  12. doi request reprint Impact of exposure accrual on sequential postmarket evaluations: a simulation study
    Judith C Maro
    Engineering Systems Division, Massachusetts Institute of Technology, Cambridge, MA, USA
    Pharmacoepidemiol Drug Saf 20:1184-91. 2011
    ..We discuss the role of SDS analyses in the US Food and Drug Administration's planned Sentinel System and suggest the outline of a decision-analytic framework that might aid regulatory authorities in planning postmarket surveillance...
  13. pmc Validation of claims-based algorithms for identification of high-grade cervical dysplasia and cervical cancer
    Seoyoung C Kim
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital Harvard Medical School, Boston, MA, USA Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:1239-44. 2013
    ..High-grade cervical dysplasia or cervical intraepithelial neoplasia grade 2 or worse has been widely used as a surrogate endpoint in cervical cancer screening or prevention trials...
  14. ncbi request reprint Real-time vaccine safety surveillance for the early detection of adverse events
    Tracy A Lieu
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA
    Med Care 45:S89-95. 2007
    ..Sequential testing procedures are needed to detect vaccine or drug safety problems as soon as possible after introduction...
  15. ncbi request reprint Minimizing signal detection time in postmarket sequential analysis: balancing positive predictive value and sensitivity
    Judith C Maro
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 23:839-48. 2014
    ....
  16. ncbi request reprint Orphan therapies: making best use of postmarket data
    Judith C Maro
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, 6th Floor, Boston, MA, 02215, USA
    J Gen Intern Med 29:745-51. 2014
    ..Such a network could support sequential statistical analyses designed to detect early warnings of excess risks. We use a simulated example to explore the circumstances under which a distributed network may prove advantageous...
  17. ncbi request reprint Confounding adjustment in comparative effectiveness research conducted within distributed research networks
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Med Care 51:S4-10. 2013
    ..An essential component of a fully functional DRN is the capability to perform robust statistical analyses to produce valid, actionable evidence without compromising patient privacy, data security, or proprietary interests...
  18. ncbi request reprint Data quality assessment for comparative effectiveness research in distributed data networks
    Jeffrey S Brown
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Med Care 51:S22-9. 2013
    ..Often, distributed networks that combine information from multiple sources are needed to generate this real-world evidence...
  19. doi request reprint Medical product safety surveillance: how many databases to use?
    Judith C Maro
    Engineering Systems Division, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Epidemiology 24:692-9. 2013
    ..Appropriate planning allows the most efficient use of public health dollars dedicated to medical product surveillance efforts...
  20. ncbi request reprint A controlled study of the effects of state surveillance on indicators of problematic and non-problematic benzodiazepine use in a Medicaid population
    Dennis Ross-Degnan
    Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Int J Psychiatry Med 34:103-23. 2004
    ..We evaluated the effects of physician surveillance through a Triplicate Prescription Program (TPP) on problematic and non-problematic BZ use...
  21. ncbi request reprint Effect of the Heart At Work program on awareness of risk factors, self-efficacy, and health behaviors
    Cheryl Pegus
    Pfizer, Inc, New York, N Y, USA
    J Occup Environ Med 44:228-36. 2002
    ..They also were more likely to begin treatment for hypertension, to report fewer sick days, and to have plans to improve their diet and lose weight. These findings suggest that the Heart At Work program had a favorable overall impact...