Kevin G Broadbelt

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Brainstem deficiency of the 14-3-3 regulator of serotonin synthesis: a proteomics analysis in the sudden infant death syndrome
    Kevin G Broadbelt
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell Proteomics 11:M111.009530. 2012
  2. ncbi Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American population
    Kevin G Broadbelt
    Department of Pathology, Enders Building Room 1111, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Res 66:631-5. 2009
  3. ncbi Neuroanatomic relationships between the GABAergic and serotonergic systems in the developing human medulla
    Kevin G Broadbelt
    Department of Pathology, Children s Hospital Boston, Boston, MA 02115, USA
    Auton Neurosci 154:30-41. 2010
  4. ncbi Decreased GABAA receptor binding in the medullary serotonergic system in the sudden infant death syndrome
    Kevin G Broadbelt
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    J Neuropathol Exp Neurol 70:799-810. 2011
  5. ncbi Lack of association of the serotonin transporter polymorphism with the sudden infant death syndrome in the San Diego Dataset
    David S Paterson
    Department of Pathology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatr Res 68:409-13. 2010
  6. ncbi Late development of the GABAergic system in the human cerebral cortex and white matter
    Gang Xu
    Department of Pathology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    J Neuropathol Exp Neurol 70:841-58. 2011
  7. ncbi The serotonergic anatomy of the developing human medulla oblongata: implications for pediatric disorders of homeostasis
    Hannah C Kinney
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, United States
    J Chem Neuroanat 41:182-99. 2011

Detail Information

Publications7

  1. ncbi Brainstem deficiency of the 14-3-3 regulator of serotonin synthesis: a proteomics analysis in the sudden infant death syndrome
    Kevin G Broadbelt
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell Proteomics 11:M111.009530. 2012
    ..These data suggest a potential molecular defect in SIDS related to TPH2 regulation, as 14-3-3 is critical in this process...
  2. ncbi Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American population
    Kevin G Broadbelt
    Department of Pathology, Enders Building Room 1111, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Res 66:631-5. 2009
    ..128-(191_192)dupA). The polymorphism seems to be a common, likely nonpathogenic, variant in the African-American population...
  3. ncbi Neuroanatomic relationships between the GABAergic and serotonergic systems in the developing human medulla
    Kevin G Broadbelt
    Department of Pathology, Children s Hospital Boston, Boston, MA 02115, USA
    Auton Neurosci 154:30-41. 2010
    ..The developmental profile of GABAergic markers changed dramatically relative to the 5-HT markers. These data provide baseline information for medullary studies of human pediatric disorders, such as sudden infant death syndrome...
  4. ncbi Decreased GABAA receptor binding in the medullary serotonergic system in the sudden infant death syndrome
    Kevin G Broadbelt
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    J Neuropathol Exp Neurol 70:799-810. 2011
    ..026). These data suggest that medullary GABAA receptors are abnormal in SIDS infants and that SIDS is a complex disorder of a homeostatic network in the medulla that involves deficits of the GABAergic and 5-HT systems...
  5. ncbi Lack of association of the serotonin transporter polymorphism with the sudden infant death syndrome in the San Diego Dataset
    David S Paterson
    Department of Pathology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatr Res 68:409-13. 2010
    ..These observations do not support previous findings that the L allele and/or LL genotype of the 5-HTTLPR are associated with SIDS...
  6. ncbi Late development of the GABAergic system in the human cerebral cortex and white matter
    Gang Xu
    Department of Pathology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    J Neuropathol Exp Neurol 70:841-58. 2011
    ..This period corresponds to the peak window of vulnerability to perinatal hypoxia-ischemia in which GABAergic neurons are potentially developmentally susceptible, including in the preterm infant...
  7. ncbi The serotonergic anatomy of the developing human medulla oblongata: implications for pediatric disorders of homeostasis
    Hannah C Kinney
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, United States
    J Chem Neuroanat 41:182-99. 2011
    ..The delineation of the development and organization of the human caudal 5-HT system provides the critical foundation for the neuropathologic elucidation of its disorders directly in the human brain...