Research Topics
| Jennifer C BrittonSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Amygdala and fusiform gyrus temporal dynamics: responses to negative facial expressionsJennifer C Britton
Psychiatric Neuroimaging Research Program and Martinos Biomedical Imaging Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
BMC Neurosci 9:44. 2008..Percent signal changes within anatomic regions-of-interest (amygdala and fusiform gyrus) were calculated to examine the temporal dynamics of neural response and any response differences based on face type...
Differential subjective and psychophysiological responses to socially and nonsocially generated emotional stimuliJennifer C Britton
Neuroscience Program, University of Michigan, USA
Emotion 6:150-5. 2006..Heart rate deceleration was more responsive to nonsocially generated emotions. Taken together, these findings suggest that sociality affects the physiological profile of responses to emotional valence...- Facial expressions and complex IAPS pictures: common and differential networksJennifer C Britton
Department of Neuroscience, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 31:906-19. 2006..For the most part, these regions were activated in response to all specific emotions; however, some regions responded only to a subset... - Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuliIsrael Liberzon
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
Am J Psychiatry 164:1250-8. 2007..The authors used [(15)O]H(2)O positron emission tomography (PET) on subjects with posttraumatic stress disorder (PTSD) to study these circuits... 
Medial prefrontal cortex and right insula activity predict plasma ACTH response to trauma recallAnthony P King
Psychiatry, University of Michigan, Ann Arbor, MI, USA
Neuroimage 47:872-80. 2009..These results support the hypotheses that right insula is involved in psychological activation of the LHPA axis and that rostral mPFC may negatively modulate LHPA axis responses...- Neural correlates of social and nonsocial emotions: An fMRI studyJennifer C Britton
Neuroscience Program, University of Michigan, Ann Arbor, MI 48109
Neuroimage 31:397-409. 2006..Overall, these findings highlight that sociality has a key role in processing emotional valence, which may have implications for patient populations with social and emotional deficits... - Corticolimbic blood flow in posttraumatic stress disorder during script-driven imageryJennifer C Britton
Neuroscience Program, University of Michigan, Michigan, USA
Biol Psychiatry 57:832-40. 2005..CONCLUSIONS: Trauma-specific patterns may represent potential compensatory changes to traumatic reminders, while patterns observed only in the PTSD group may reflect neural substrates specific to PTSD pathophysiology... - Altered central micro-opioid receptor binding after psychological traumaIsrael Liberzon
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
Biol Psychiatry 61:1030-8. 2007..The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing... - Functional MRI study of specific animal phobia using an event-related emotional counting stroop paradigmJennifer C Britton
Psychiatric Neuroimaging Research Program and Martinos Biomedical Imaging Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
Depress Anxiety 26:796-805. 2009..Emotional interference tasks may be useful in probing anterior cingulate cortex (ACC) function to understand abnormal attentional study in individuals with specific phobia... - Habituation of rostral anterior cingulate cortex to repeated emotionally salient picturesK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Ann Arbor, MI, USA
Neuropsychopharmacology 28:1344-50. 2003..These findings highlight the phasic activity of the rACC in emotional processing consistent with habituation... - Neural response to emotional salience in schizophreniaStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
Neuropsychopharmacology 30:984-95. 2005..Reduced modulation of visual cortex by emotionally salient stimuli also suggests a failure to organize cerebral activity at a global level... - Neural correlates of novelty and face-age effects in young and elderly adultsChristopher I Wright
Laboratory of Aging and Emotion, Psychiatric Neuroimaging Research Program, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, CNY 2, Charlestown, MA 02129, USA
Neuroimage 42:956-68. 2008..e., an age in-group effect). Differences in anatomic localization and behavioral results suggest that novelty and age in-group effects were differentially processed in the amygdala... - Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a fMRI studyK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109-0118, USA
Biol Psychiatry 53:211-5. 2003..CONCLUSIONS: Our findings demonstrate that individual behavioral data are useful in improving detection of activation in block-design functional imaging studies... - Neuroticism associated with neural activation patterns to positive stimuliJennifer C Britton
Department of Neuroscience, University of Michigan, Ann Arbor, MI, USA
Psychiatry Res 156:263-7. 2007..Neuroticism directly correlated with dorsomedial prefrontal cortex activation in response to positive stimuli. Dorsomedial prefrontal cortex correlations may reflect increased self-association in individuals with high neuroticism... - Pilot study of response inhibition and error processing in the posterior medial prefrontal cortex in healthy youthKate Dimond Fitzgerald
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
J Child Psychol Psychiatry 49:986-94. 2008..Developmental neuroimaging studies of response inhibition have found pMFC activation, but the possible contribution of error-related activation during inhibitory processing has not been well studied in youth... - Anxiety sensitivity correlates with two indices of right anterior insula structure in specific animal phobiaIsabelle M Rosso
Neuroimaging Center, McLean Hospital, Belmont, Massachusetts 02478, USA
Depress Anxiety 27:1104-10. 2010..We examined whether AS was significantly correlated with right anterior insula volume and thickness among adults with specific animal phobia (SAP) and healthy comparison (HC) subjects... - Neural correlates of anxiety sensitivity during masked presentation of affective facesWilliam D S Killgore
Affective Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts
Depress Anxiety 28:243-9. 2011..We hypothesized that insular responses to fear-related stimuli would be primarily related to the Physical Concerns subscale of the ASI, particularly for a sample of subjects with specific phobias... - Neural correlates of traumatic recall in posttraumatic stress disorderIsrael Liberzon
Psychiatry Service, Ann Arbor Veterans Affairs Medical Center, MI 48109, USA
Stress 6:151-6. 2003.... - D-cycloserine inhibits amygdala responses during repeated presentations of facesJennifer C Britton
Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA
CNS Spectr 12:600-5. 2007..However, the underlying brain mechanisms mediating this fear reduction have yet to be determined... - Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorderK Luan Phan
Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
Arch Gen Psychiatry 63:184-92. 2006..Activation of the amygdala and lack of ventral MPFC deactivation to negatively valenced images in combat controls may reflect compensatory changes after trauma exposure that are not associated with PTSD... - Neural correlates of individual ratings of emotional salience: a trial-related fMRI studyK Luan Phan
Department of Psychiatry and Behvioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
Neuroimage 21:768-80. 2004..The findings highlight both overlapping and segregated neural representations of intrinsic value and personal relevance during the appraisal of emotional stimuli...