Adrian W Briggs

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
    Adrian W Briggs
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Nucleic Acids Res 40:e117. 2012
  2. doi request reprint Rapid retrieval of DNA target sequences by primer extension capture
    Adrian W Briggs
    Department of Genetics, Harvard Medical School, Boston, MA, USA
    Methods Mol Biol 772:145-54. 2011
  3. doi request reprint Preparation of next-generation sequencing libraries from damaged DNA
    Adrian W Briggs
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Methods Mol Biol 840:143-54. 2012
  4. doi request reprint Genetic history of an archaic hominin group from Denisova Cave in Siberia
    David Reich
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 468:1053-60. 2010
  5. pmc Optimization of scarless human stem cell genome editing
    Luhan Yang
    Department of Genetics, Harvard Medical School, Boston, 02115 MA, USA, Biological and Biomedical Sciences Program, Harvard Medical School, Boston, 02115 MA, USA, Children s Hospital, Boston, 02115 MA, USA, Chemistry and Chemical Biology Program, Harvard, 02138 Cambridge, MA, USA and Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, 02138 MA, USA
    Nucleic Acids Res 41:9049-61. 2013
  6. pmc Stable gene targeting in human cells using single-strand oligonucleotides with modified bases
    Xavier Rios
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e36697. 2012

Collaborators

  • George M Church
  • Feng Zhang
  • Patricia Heyn
  • Xavier Rios
  • Luhan Yang
  • David Reich
  • Prashant Mali
  • Alejandro De Los Angeles
  • Joyce L Yang
  • Po Yi Huang
  • Caroline Kim-Kiselak
  • Marc G├╝ell
  • John Aach
  • Susan Byrne
  • George Daley
  • Jonathan G Seidman
  • Danos Christodoulou
  • Josh M Gorham
  • Qiaomei Fu
  • Michael V Shunkov
  • Heng Li
  • Montgomery Slatkin
  • Martin Kircher
  • Michael Richards
  • Richard E Green
  • Svante Paabo
  • Nick Patterson
  • Jean Jacques Hublin
  • Jeffrey M Good
  • Anatoli P Derevianko
  • Evan E Eichler
  • Matthias Meyer
  • Sahra Talamo
  • Tomislav Maricic
  • Udo Stenzel
  • Eric Y Durand
  • Mark Stoneking
  • Janet Kelso
  • Tomas Marques-Bonet
  • Swapan Mallick
  • Can Alkan
  • Bence Viola
  • Johannes Krause
  • Philip L F Johnson

Detail Information

Publications6

  1. pmc Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
    Adrian W Briggs
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Nucleic Acids Res 40:e117. 2012
    ....
  2. doi request reprint Rapid retrieval of DNA target sequences by primer extension capture
    Adrian W Briggs
    Department of Genetics, Harvard Medical School, Boston, MA, USA
    Methods Mol Biol 772:145-54. 2011
    ..PEC promises useful applications in studies such as ancient DNA or forensic sequencing, taxonomic surveying of metagenomic samples, or genomic mapping of repetitive elements...
  3. doi request reprint Preparation of next-generation sequencing libraries from damaged DNA
    Adrian W Briggs
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Methods Mol Biol 840:143-54. 2012
    ..Starting from an aliquot of DNA extract, a finished, highly amplified library can be generated in 5 h, or under 3 h if uracil removal is not required...
  4. doi request reprint Genetic history of an archaic hominin group from Denisova Cave in Siberia
    David Reich
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 468:1053-60. 2010
    ..This tooth shares no derived morphological features with Neanderthals or modern humans, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans...
  5. pmc Optimization of scarless human stem cell genome editing
    Luhan Yang
    Department of Genetics, Harvard Medical School, Boston, 02115 MA, USA, Biological and Biomedical Sciences Program, Harvard Medical School, Boston, 02115 MA, USA, Children s Hospital, Boston, 02115 MA, USA, Chemistry and Chemical Biology Program, Harvard, 02138 Cambridge, MA, USA and Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, 02138 MA, USA
    Nucleic Acids Res 41:9049-61. 2013
    ..0 versus 0.6%) when combined with ssODN donors in hiPSCs. Using the optimal design, we demonstrated a streamlined process to generated seamlessly genome corrected hiPSCs within 3 weeks. ..
  6. pmc Stable gene targeting in human cells using single-strand oligonucleotides with modified bases
    Xavier Rios
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e36697. 2012
    ..Further optimization of this method should allow rapid and scalable genome engineering in human cells...