M Bogyo

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes
    M Bogyo
    Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
    Chem Biol 5:307-20. 1998
  2. ncbi request reprint Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense
    C R Caffrey
    Tropical Disease Research Unit, Department of Pathology, University of California San Francisco, VAMC, 4150 Clement Street-113B, San Francisco, CA 94121, USA
    Mol Biochem Parasitol 118:61-73. 2001

Collaborators

Detail Information

Publications2

  1. ncbi request reprint Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes
    M Bogyo
    Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
    Chem Biol 5:307-20. 1998
    ..Although mutational studies in yeast have begun to define substrate specificities of individual catalytically active beta subunits, little is known about the principles that govern substrate hydrolysis by the proteasome...
  2. ncbi request reprint Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense
    C R Caffrey
    Tropical Disease Research Unit, Department of Pathology, University of California San Francisco, VAMC, 4150 Clement Street-113B, San Francisco, CA 94121, USA
    Mol Biochem Parasitol 118:61-73. 2001
    ..S2 subsite mapping of rhodesain and cruzain with fluorogenic peptidyl substrates demonstrates that the presence of alanine rather than glutamate at S2 prevents rhodesain from cleaving substrates in which P2 is arginine...