Benjamin S Bleier

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Evaluation of a polysaccharide gel for laser-assisted skull base repair
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Am J Rhinol Allergy 27:148-50. 2013
  2. doi request reprint P-glycoprotein functions as an immunomodulator in healthy human primary nasal epithelial cells
    Benjamin S Bleier
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Int Forum Allergy Rhinol 3:433-8. 2013
  3. pmc Permeabilization of the blood-brain barrier via mucosal engrafting: implications for drug delivery to the brain
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 8:e61694. 2013
  4. doi request reprint The accessory posterolateral nerve: an immunohistological analysis
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Am J Rhinol Allergy 26:271-3. 2012
  5. doi request reprint The bipedicled anterior septal flap: a radioanatomic and cadaveric study
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Laryngoscope 121:1367-71. 2011
  6. doi request reprint Mucocele rate after endoscopic skull base reconstruction using vascularized pedicled flaps
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Rhinol Allergy 25:186-7. 2011
  7. doi request reprint Anteriorly based pedicled flaps for skull base reconstruction
    Joshua C Meier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston MA 02114, USA
    Adv Otorhinolaryngol 74:64-70. 2013
  8. doi request reprint Regional expression of epithelial MDR1/P-glycoprotein in chronic rhinosinusitis with and without nasal polyposis
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Int Forum Allergy Rhinol 2:122-5. 2012
  9. doi request reprint Temporospatial quantification of fluorescein-labeled sinonasal irrigation delivery
    Benjamin S Bleier
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    Int Forum Allergy Rhinol 1:361-5. 2011
  10. doi request reprint Novel techniques and the future of skull base reconstruction
    Joshua C Meier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    Adv Otorhinolaryngol 74:174-83. 2013

Detail Information

Publications16

  1. doi request reprint Evaluation of a polysaccharide gel for laser-assisted skull base repair
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Am J Rhinol Allergy 27:148-50. 2013
    ..This study was designed to define the thermal and inflammatory profile of a novel polysaccharide soldering gel, to assess the burst strength of the repair, and to determine the time required for solder resorption...
  2. doi request reprint P-glycoprotein functions as an immunomodulator in healthy human primary nasal epithelial cells
    Benjamin S Bleier
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Int Forum Allergy Rhinol 3:433-8. 2013
    ..The objective of this study is to therefore determine whether P-gp participates in the regulation of cytokine secretion in sinonasal epithelial cells...
  3. pmc Permeabilization of the blood-brain barrier via mucosal engrafting: implications for drug delivery to the brain
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 8:e61694. 2013
    ..This proof of principle study demonstrates that mucosal engrafting represents the first permanent and stable method of bypassing the BBB thereby providing a pathway for HMW therapeutics directly into the CNS...
  4. doi request reprint The accessory posterolateral nerve: an immunohistological analysis
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Am J Rhinol Allergy 26:271-3. 2012
    ..The goal of this study was to characterize these accessory posterolateral nerves by immunohistochemistry to determine their morphology and composition...
  5. doi request reprint The bipedicled anterior septal flap: a radioanatomic and cadaveric study
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Laryngoscope 121:1367-71. 2011
    ..The objective of this study was to define a novel bipedicled anterior septal (BAS) flap that is hypothesized to be capable of providing reproducible coverage of these difficult areas...
  6. doi request reprint Mucocele rate after endoscopic skull base reconstruction using vascularized pedicled flaps
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Rhinol Allergy 25:186-7. 2011
    ..The purpose of this study was to determine the rate of mucocele formation after nasoseptal flap reconstruction without mucosal stripping...
  7. doi request reprint Anteriorly based pedicled flaps for skull base reconstruction
    Joshua C Meier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston MA 02114, USA
    Adv Otorhinolaryngol 74:64-70. 2013
    ....
  8. doi request reprint Regional expression of epithelial MDR1/P-glycoprotein in chronic rhinosinusitis with and without nasal polyposis
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Int Forum Allergy Rhinol 2:122-5. 2012
    ..The purpose of this study is to determine the pattern and degree of epithelial P-gp expression in chronic rhinosinusitis (CRS) with nasal polyposis (CRSwNP) or CRS without nasal polyposis (CRSsNP)...
  9. doi request reprint Temporospatial quantification of fluorescein-labeled sinonasal irrigation delivery
    Benjamin S Bleier
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    Int Forum Allergy Rhinol 1:361-5. 2011
    ..Despite multiple distribution studies, there remains a need for a method capable quantifying not only the site and amount of agent deposition but the rate of clearance as well...
  10. doi request reprint Novel techniques and the future of skull base reconstruction
    Joshua C Meier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    Adv Otorhinolaryngol 74:174-83. 2013
    ..While laser tissue welding remains an experimental technique, continued success with these novel solder formulations may catalyze the widespread adoption of this technique for skull base repair in the near future...
  11. doi request reprint Endoscopic anatomy of the postganglionic pterygopalatine innervation of the posterolateral nasal mucosa
    Benjamin S Bleier
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Int Forum Allergy Rhinol 1:113-7. 2011
    ..The purpose of this study is correlate these anatomic descriptions with endoscopic findings and to define the pattern and location of the posterolateral neurovascular rami...
  12. doi request reprint Dose quantification of topical drug delivery to the paranasal sinuses by fluorescein luminosity calculation
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    Int Forum Allergy Rhinol 2:316-20. 2012
    ..The purpose of this study is to refine this technique to provide an accurate method of determining concentration of dose delivery as well...
  13. doi request reprint Primary human sinonasal epithelial cell culture model for topical drug delivery in patients with chronic rhinosinusitis with nasal polyposis
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    J Pharm Pharmacol 64:449-56. 2012
    ....
  14. doi request reprint Preliminary study on the stability of beta-2 transferrin in extracorporeal cerebrospinal fluid
    Benjamin S Bleier
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Otolaryngol Head Neck Surg 144:101-3. 2011
    ..The purpose of this study is to understand how age, storage temperature, and exposure to mucus affect the ability to detect beta-2 transferrin in CSF...
  15. doi request reprint P-glycoprotein is a marker of tissue eosinophilia and radiographic inflammation in chronic rhinosinusitis without nasal polyps
    Rachel E Feldman
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Int Forum Allergy Rhinol 3:684-7. 2013
    ..The goal of this study is to determine if P-gp expression is associated with degree of eosinophilia and severity of radiographic inflammation in patients with CRS without polyps (CRSsNP)...
  16. doi request reprint Outcomes analysis in epistaxis management: development of a therapeutic algorithm
    Josef Shargorodsky
    Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
    Otolaryngol Head Neck Surg 149:390-8. 2013
    ..This study explored the outcomes of epistaxis treatment modalities to optimize management and enable the development of a therapeutic algorithm...