George L Blackburn

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial
    Ikuyo Imayama
    Public Health Sciences Division, Fred Hutchison Cancer Research Center, Seattle, WA, USA
    Int J Behav Nutr Phys Act 8:118. 2011
  2. ncbi Metabolic considerations in management of surgical patients
    George L Blackburn
    Center for the Study of Nutrition Medicine, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Feldberg 880 East Campus, 330 Brookline Avenue, Boston, MA 02215, USA
    Surg Clin North Am 91:467-80. 2011
  3. ncbi Effective surgical treatment of diabetes for the obese patient
    George L Blackburn
    Harvard Medical School, Center for Study of Nutrition Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Curr Diab Rep 6:85-7. 2006
  4. ncbi Therapy insight: weight-loss surgery and major cardiovascular risk factors
    George L Blackburn
    Division of Nutrition, Harvard Medical School, Boston, MA 02215, USA
    Nat Clin Pract Cardiovasc Med 2:585-91. 2005
  5. ncbi Physician's guide to the new 2005 dietary guidelines: how best to counsel patients
    George L Blackburn
    Division of Nutrition, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Cleve Clin J Med 72:609-18. 2005
  6. ncbi Solutions in weight control: lessons from gastric surgery
    George L Blackburn
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 82:248S-252S. 2005
  7. ncbi Teaching, learning, doing: best practices in education
    George L Blackburn
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 82:218S-221S. 2005
  8. ncbi Science-based solutions to obesity: what are the roles of academia, government, industry, and health care?
    George L Blackburn
    Harvard Medical School Division of Nutrition, Boston, MA, USA
    Am J Clin Nutr 82:207S-210S. 2005
  9. ncbi Effects of weight loss surgeries on liver disease
    George L Blackburn
    Division of Nutrition Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Semin Liver Dis 24:371-9. 2004
  10. ncbi Pharmacotherapy to reduce visceral fat
    George L Blackburn
    Division of Nutrition, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Cornerstone 7:52-60. 2005

Collaborators

Detail Information

Publications64

  1. ncbi Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial
    Ikuyo Imayama
    Public Health Sciences Division, Fred Hutchison Cancer Research Center, Seattle, WA, USA
    Int J Behav Nutr Phys Act 8:118. 2011
    ..abstract:..
  2. ncbi Metabolic considerations in management of surgical patients
    George L Blackburn
    Center for the Study of Nutrition Medicine, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Feldberg 880 East Campus, 330 Brookline Avenue, Boston, MA 02215, USA
    Surg Clin North Am 91:467-80. 2011
    ..Hypercatabolism has been associated with severe complications related to hyperglycemia, hypoproteinemia, and immunosuppression. Proper metabolic support is essential to restore homeostasis and ensure survival...
  3. ncbi Effective surgical treatment of diabetes for the obese patient
    George L Blackburn
    Harvard Medical School, Center for Study of Nutrition Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Curr Diab Rep 6:85-7. 2006
  4. ncbi Therapy insight: weight-loss surgery and major cardiovascular risk factors
    George L Blackburn
    Division of Nutrition, Harvard Medical School, Boston, MA 02215, USA
    Nat Clin Pract Cardiovasc Med 2:585-91. 2005
    ..Today's weight-loss operations are safe, effective and potentially life-saving options for severely obese cardiology patients. This review describes weight-loss surgery procedures and their effects on cardiovascular risk factors...
  5. ncbi Physician's guide to the new 2005 dietary guidelines: how best to counsel patients
    George L Blackburn
    Division of Nutrition, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Cleve Clin J Med 72:609-18. 2005
    ..Health care providers can influence patients' food and activity choices by providing specific counseling and presenting straightforward information...
  6. ncbi Solutions in weight control: lessons from gastric surgery
    George L Blackburn
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 82:248S-252S. 2005
    ..Researchers have begun to explore the molecular pathways responsible for these outcomes. Identifying the differences between surgical and nonsurgical treatments will eventually lead to new therapeutic options...
  7. ncbi Teaching, learning, doing: best practices in education
    George L Blackburn
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 82:218S-221S. 2005
    ..The process of change is challenging, particularly in adults. Best practices in teaching and learning can help physicians be more effective agents of change...
  8. ncbi Science-based solutions to obesity: what are the roles of academia, government, industry, and health care?
    George L Blackburn
    Harvard Medical School Division of Nutrition, Boston, MA, USA
    Am J Clin Nutr 82:207S-210S. 2005
    ....
  9. ncbi Effects of weight loss surgeries on liver disease
    George L Blackburn
    Division of Nutrition Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Semin Liver Dis 24:371-9. 2004
    ..Recent findings indicate that key features of NAFLD and NASH improve or resolve dramatically with weight loss. This article discusses weight loss surgeries and their effects on liver disease...
  10. ncbi Pharmacotherapy to reduce visceral fat
    George L Blackburn
    Division of Nutrition, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Cornerstone 7:52-60. 2005
    ..Weight loss, particularly a reduction in waist circumference, improves insulin sensitivity, lipid profile, and serum adipocytokines, thereby reducing the risk of developing chronic disease and CVD...
  11. ncbi Lifestyle interventions for the treatment of class III obesity: a primary target for nutrition medicine in the obesity epidemic
    George L Blackburn
    Beth Israel Deaconess Medical Center, Center for the Study of Nutrition Medicine, Boston, MA, USA
    Am J Clin Nutr 91:289S-292S. 2010
    ..Lifestyle interventions specifically targeted toward the class III obese cohort should be a high priority in nutrition medicine...
  12. ncbi Expanding the limits of treatment--new strategic initiatives
    George L Blackburn
    Division of Nutrition, Harvard Medical School, Boston, MA, USA
    J Am Diet Assoc 105:S131-5. 2005
    ..Work to date has paid off for millions of persons. We have stopped the epidemic of obesity. Now it is time to do more by joining health care practitioners with all other stakeholders in the effort to prevent and reverse it...
  13. ncbi The low-fat imperative
    George L Blackburn
    Beth Israel Deaconess Medical Center, Center for the Study of Nutrition Medicine, Boston, MA, USA
    Obesity (Silver Spring) 16:5-6. 2008
  14. ncbi Dietary fat reduction and breast cancer outcome: results from the Women's Intervention Nutrition Study (WINS)
    George L Blackburn
    Beth Israel Deaconess Medical Center, Center for the Study of Nutrition Medicine, Boston, MA 02215, USA
    Am J Clin Nutr 86:s878-81. 2007
    ..The results of the Women's Intervention Nutrition Study may therefore contribute to knowledge of the role of insulin resistance in cancer risk...
  15. ncbi Expert panel on weight loss surgery: executive report update
    George L Blackburn
    Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Obesity (Silver Spring) 17:842-62. 2009
    ..We expect them to have far-reaching effects of the development of health care policy and the practice of WLS...
  16. ncbi Nutrition support in the intensive care unit: an evolving science
    George L Blackburn
    Center for the Study of Nutrition Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Feldberg 880, East Campus, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Surg 145:533-8. 2010
    ..It will review parenteral nutrition from its inception to its current standing in ICU patient care and discuss the future role of parenteral nutrition in a rapidly changing and increasingly diverse population...
  17. ncbi From bench to bedside: novel mechanisms and therapeutic advances through the development of selective peroxisome proliferator-activated receptor gamma modulators
    George L Blackburn
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02155, USA
    Am J Clin Nutr 91:251S-253S. 2010
    ..These molecules offer a new direction in the search for more specific PPARgamma activators that will retain efficacy for the treatment of diabetes without major side effects...
  18. ncbi Best practices in policy and access (coding and reimbursement) for weight loss surgery
    Scott A Shikora
    Tufts Medical Center, Boston, Massachusetts, USA
    Obesity (Silver Spring) 17:918-23. 2009
    ..However, access to WLS often varies by payer and region. Currently, there are no uniform criteria for determining patient appropriateness for surgery...
  19. ncbi Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells
    Zhiming Mai
    Nutrition Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Mol Carcinog 46:534-42. 2007
    ....
  20. ncbi Soy phytochemicals synergistically enhance the preventive effect of tamoxifen on the growth of estrogen-dependent human breast carcinoma in mice
    Zhiming Mai
    Nutrition Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Burlington 5, Boston, MA 02215, USA
    Carcinogenesis 28:1217-23. 2007
    ..The results from our studies suggest that further investigations may be warranted to determine if the combination of TAM and bioactive soy components may be used for prevention and/or treatment of estrogen-dependent BRCA...
  21. ncbi Best practice updates for surgical care in weight loss surgery
    John J Kelly
    Department of Surgery, University of Massachusetts Medical Center, Worcester, Massachusetts, USA
    Obesity (Silver Spring) 17:863-70. 2009
    ..Key factors in patient safety include surgical risk factors, type of procedure, surgeon training, and facility certification...
  22. ncbi Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice
    Yi Gong
    Nutrition Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Int J Cancer 129:1042-52. 2011
    ..Our results support that T1 may be an efficacious and safe chemopreventive or therapeutic agent against prostate cancer progression...
  23. ncbi Serum levels of interleukin-6 and C-reactive protein correlate with body mass index across the broad range of obesity
    Lalita Khaodhiar
    Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    JPEN J Parenter Enteral Nutr 28:410-5. 2004
    ....
  24. ncbi Progression to androgen-independent LNCaP human prostate tumors: cellular and molecular alterations
    Jin Rong Zhou
    Nutrition Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Burlington 554B, Boston, MA 02215, USA
    Int J Cancer 110:800-6. 2004
    ....
  25. ncbi Weight-loss programs in convenient care clinics: a prospective cohort study
    Samuel Wollner
    Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Am J Health Promot 25:26-9. 2010
    ..Assess whether a convenient care clinic (CCC) medical weight-loss program can promote weight loss...
  26. ncbi Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis
    Ajita V Singh
    Nutrition/Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Cancer Res 66:1851-8. 2006
    ..This orthotopic human bladder tumor model also provides a clinically relevant experimental tool for assessing potential preventive activity of other dietary components against bladder tumor growth and metastasis...
  27. ncbi Symposium introduction: metabolic syndrome and the onset of cancer
    Jin Rong Zhou
    Division of Nutrition, Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 86:s817-9. 2007
    ..Furthermore, it will help to guide the development of effective cancer prevention strategies via nutritional and lifestyle modifications to alleviate metabolic syndrome...
  28. ncbi Laparoscopic gastric bypass surgery: outcomes
    Benjamin E Schneider
    Division of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachussets 02215, USA
    J Laparoendosc Adv Surg Tech A 13:247-55. 2003
  29. ncbi Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study
    Rowan T Chlebowski
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 West Carson St, Building J 3, Torrance, CA 90502 2064, USA
    J Natl Cancer Inst 98:1767-76. 2006
    ..We carried out a randomized, prospective, multicenter clinical trial to test the effect of a dietary intervention designed to reduce fat intake in women with resected, early-stage breast cancer receiving conventional cancer management...
  30. ncbi Soy phytochemicals and tea bioactive components synergistically inhibit androgen-sensitive human prostate tumors in mice
    Jin Rong Zhou
    Nutrition Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Nutr 133:516-21. 2003
    ..This study suggests that further research is warranted to study the role of soy and tea combination as effective nutritional regimens in prostate cancer prevention...
  31. ncbi Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components
    Jin Rong Zhou
    Nutrition Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Prostate 53:143-53. 2002
    ..Animal models that emulate human prostate cancer allow experimental analysis of the mechanisms of action of nutritional agents that show anti-prostate cancer activity...
  32. ncbi Diet and breast cancer
    George L Blackburn
    Harvard Medical School, Boston, Massachusetts 02215, USA
    J Womens Health (Larchmt) 12:183-92. 2003
    ..Results from large-scale nutritional intervention trials are expected to resolve such issues. As new and improved data on dietary factors and patterns accumulate, dietary guidelines for cancer risk reduction will become more focused...
  33. ncbi Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women
    Lalita Khaodhiar
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Menopause 15:125-32. 2008
    ..The aim of this study was to determine the effect of DRIs on hot flash symptoms in menopausal women...
  34. ncbi Coffee consumption is associated with higher plasma adiponectin concentrations in women with or without type 2 diabetes: a prospective cohort study
    Catherine J Williams
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Diabetes Care 31:504-7. 2008
    ..High consumption of caffeine-containing coffee is associated with higher adiponectin and lower inflammatory marker concentrations...
  35. ncbi Fat--the good, the bad and the trans
    George L Blackburn
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Forum Nutr 56:196-8. 2003
  36. ncbi Genistein and daidzein downregulate prostate androgen-regulated transcript-1 (PART-1) gene expression induced by dihydrotestosterone in human prostate LNCaP cancer cells
    Lunyin Yu
    Nutrition/Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Nutr 133:389-92. 2003
    ..Our studies suggest that use of the PART-1 gene as a biomarker for evaluating the efficacy of soy isoflavones on androgen-dependent prostate cancer warrants further investigation...
  37. ncbi Inflammation and foveolar hyperplasia are reduced by supplemental dietary glutamine during Helicobacter pylori infection in mice
    Susan J Hagen
    Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Nutr 139:912-8. 2009
    ..pylori-associated pathology in vivo that is accompanied by beneficial changes in the immune response to H. pylori early in infection. Thus, Gln supplementation may be an alternative therapy for reducing H. pylori-associated pathology...
  38. ncbi The ROI on weight loss at work
    George L Blackburn
    Division of Nutrition, Harvard Medical School, Boston, USA
    Harv Bus Rev 87:30, 126. 2009
    ..The financial payoff-for one Texas employer, about $2.50 in return for every dollar spent--stems from lower health care costs and reduced absenteeism...
  39. ncbi Combined inhibition of estrogen-dependent human breast carcinoma by soy and tea bioactive components in mice
    Jin Rong Zhou
    Nutrition Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Int J Cancer 108:8-14. 2004
    ..Our study suggests that dietary SPC plus GT may be used as a potential effective dietary regimen for inhibiting progression of estrogen-dependent breast cancer...
  40. ncbi The metabolic syndrome: a call to action
    Antonio M Gotto
    Office of the Dean, Joan and Sanford I Weill Medical College of Cornell University, New York, New York, USA
    Coron Artery Dis 17:77-80. 2006
    ..While more research is needed to understand the pathology of the metabolic syndrome, there is no ambiguity that physicians should treat cardiovascular risk factors in individuals with metabolic syndrome...
  41. ncbi Building a better food pyramid
    George L Blackburn
    Health News 8:2-3. 2002
  42. ncbi I read that nearly a quarter of adult Americans have "metabolic syndrome". What is this malady, and how can I prevent it?
    George L Blackburn
    Health News 8:12. 2002
  43. ncbi Diet and breast cancer recurrence
    Rowan T Chlebowski
    JAMA 298:2135; author reply 2135-6. 2007
  44. ncbi Comparison of weight-loss diets
    Steven B Heymsfield
    JAMA 298:173-4; author reply 174-5. 2007
  45. ncbi The skinny on obesity and cancer. Obesity increases the risk of death from cancer, but being overweight isn't inescapable
    George L Blackburn
    Health News 9:3. 2003
  46. ncbi Dietary patterns in women treated for breast cancer who successfully reduce fat intake: the Women's Intervention Nutrition Study (WINS)
    Barbara L Winters
    American Health Foundation, New York, NY, USA
    J Am Diet Assoc 104:551-9. 2004
    ..The objectives of this study were to assess the types of dietary changes made by women who successfully reduced their fat intake in response to low-fat diet instruction and to evaluate the effects of these changes on nutrient intake...
  47. ncbi Salmon and PCBs. Wild or farmed, salmon is still a healthful choice
    George L Blackburn
    Health News 9:3. 2003
  48. ncbi "Vegging out" for better health? Vegetarians may have healthier, longer lives than their carnivorous counterparts
    George L Blackburn
    Health News 9:8-9. 2003
  49. ncbi I know breakfast is the most important meal of the day, but what are the elements of a good breakfast?
    George L Blackburn
    Health News 8:12. 2002
  50. ncbi Aspartame: review of safety
    Harriett H Butchko
    Medical and Scientific Affairs, The NutraSweet Company, Mt Prospect, Illinois 60056, USA
    Regul Toxicol Pharmacol 35:S1-93. 2002
    ....
  51. ncbi Salt shakedown. DASH diet beats salt restriction at lowering blood pressure
    George L Blackburn
    Health News 8:5. 2002
  52. ncbi Where should your omega-3s come from? The fish scare is overblown. Eating omega-3-rich fish twice a week does far more good than harm
    George L Blackburn
    Health News 10:5. 2004
  53. ncbi I manage my type 2 diabetes with lifestyle modifications and noninsulin blood sugar-controlling medications. I know I should avoid regular soft drinks, but would diet drinks or carbonated water be OK for me?
    George L Blackburn
    Health News 8:12. 2002
  54. ncbi Questions and answers. Why do I sometimes get abdominal cramps and diarrhea when I eat sugar-free of low-calorie foods?
    George L Blackburn
    Health News 9:12. 2003
  55. ncbi Making good decisions about diet: weight loss is not weight maintenance
    George L Blackburn
    Cleve Clin J Med 69:864-5, 869. 2002
  56. ncbi Low-carb diet lowdown. The long-term safety and efficacy of these diets remain unclear
    George L Blackburn
    Health News 9:1-2. 2003
  57. ncbi Sugar's not-so-sweet revenge. Avoid added sugar, say nutrition experts
    George L Blackburn
    Health News 9:3. 2003
  58. ncbi Long-term food consumption and body weight changes in neotame safety studies are consistent with the allometric relationship observed for other sweeteners and during dietary restrictions
    W Gary Flamm
    AAC Consulting Group, Vero Beach, FL, USA
    Regul Toxicol Pharmacol 38:144-56. 2003
    ..An approach using objective criteria is proposed to delineate BW changes due to toxicity from those secondary to reduced FC...
  59. ncbi Say "nuts" to diabetes? Nuts may reduce your risk of diabetes, but don't overdo it
    George L Blackburn
    Health News 9:4. 2003
  60. ncbi Evidence-based recommendations for best practices in weight loss surgery
    George L Blackburn
    Obes Res 13:203-4. 2005
  61. ncbi Treating type 2 diabetes. When diet and exercise aren't enough, a broad range of medications can help control our blood sugar
    George L Blackburn
    Health News 10:4-5. 2004
  62. ncbi Menu and workout makeovers. New diet and exercise guidelines bend previous rules
    George L Blackburn
    Health News 8:1-2. 2002
  63. ncbi Questions & answers. I'm confused about the new carbohydrate claims on foods. What does "low carb" really mean, and what is a net carb?
    George L Blackburn
    Health News 10:16. 2004
  64. ncbi National Health and Nutrition Examination Survey: where nutrition meets medicine for the benefit of health
    George L Blackburn
    Am J Clin Nutr 78:197-8. 2003