H A Bischoff-Ferrari

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Self-reported exercise before age 40: influence on quantitative skeletal ultrasound and fall risk in the elderly
    H A Bischoff
    Department of Orthopedics, University Hospital, Basel, Switzerland
    Arch Phys Med Rehabil 82:801-6. 2001
  2. ncbi request reprint Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y
    Heike A Bischoff-Ferrari
    Division of Aging, The Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
    Am J Clin Nutr 80:752-8. 2004
  3. ncbi request reprint Effect of seasonality and weather on fracture risk in individuals 65 years and older
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse, 258091, Zurich, Switzerland
    Osteoporos Int 18:1225-33. 2007
  4. ncbi request reprint Where do we stand on vitamin D?
    Heike Annette Bischoff-Ferrari
    Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
    Bone 41:S13-9. 2007
  5. ncbi request reprint Effect of Vitamin D on falls: a meta-analysis
    Heike A Bischoff-Ferrari
    Division of Aging, Department of Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    JAMA 291:1999-2006. 2004
  6. ncbi request reprint Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults
    Heike A Bischoff-Ferrari
    Division of Ageing, The Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Boston, Massachusetts, USA
    Am J Med 116:634-9. 2004
  7. ncbi request reprint Vitamin D receptor expression in human muscle tissue decreases with age
    H A Bischoff-Ferrari
    Department of Orthopedic Surgery, University Basel, Basel, Switzerland
    J Bone Miner Res 19:265-9. 2004
  8. pmc Additive benefit of higher testosterone levels and vitamin D plus calcium supplementation in regard to fall risk reduction among older men and women
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Gloriastrasse, 258091, Zurich, Switzerland
    Osteoporos Int 19:1307-14. 2008
  9. ncbi request reprint [Effect of vitamin D on muscle strength and relevance in regard to osteoporosis prevention]
    H A Bischoff-Ferrari
    Department of Medicine, Harvard Medical School, The Robert B Brigham Arthritis and Musculoskeletal Clinical Research Center, Boston, MA 02115, USA
    Z Rheumatol 62:518-21. 2003
  10. pmc Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trial
    Heike A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Am J Clin Nutr 87:1945-51. 2008

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Self-reported exercise before age 40: influence on quantitative skeletal ultrasound and fall risk in the elderly
    H A Bischoff
    Department of Orthopedics, University Hospital, Basel, Switzerland
    Arch Phys Med Rehabil 82:801-6. 2001
    ..To compare musculoskeletal factors with bone structure, as measured by quantitative ultrasound (QUS) at the calcaneus, and their potential to predict fall risk in geriatric inpatients...
  2. ncbi request reprint Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y
    Heike A Bischoff-Ferrari
    Division of Aging, The Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
    Am J Clin Nutr 80:752-8. 2004
    ..Vitamin D may improve muscle strength through a highly specific nuclear receptor in muscle tissue...
  3. ncbi request reprint Effect of seasonality and weather on fracture risk in individuals 65 years and older
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse, 258091, Zurich, Switzerland
    Osteoporos Int 18:1225-33. 2007
    ..05 at all sites). Younger age between 65 and 80, living in warmer states and male gender were associated with increased winter morbidity due to fractures...
  4. ncbi request reprint Where do we stand on vitamin D?
    Heike Annette Bischoff-Ferrari
    Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
    Bone 41:S13-9. 2007
    ....
  5. ncbi request reprint Effect of Vitamin D on falls: a meta-analysis
    Heike A Bischoff-Ferrari
    Division of Aging, Department of Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    JAMA 291:1999-2006. 2004
    ..Falls among elderly individuals occur frequently, increase with age, and lead to substantial morbidity and mortality. The role of vitamin D in preventing falls among elderly people has not been well established...
  6. ncbi request reprint Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults
    Heike A Bischoff-Ferrari
    Division of Ageing, The Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Boston, Massachusetts, USA
    Am J Med 116:634-9. 2004
  7. ncbi request reprint Vitamin D receptor expression in human muscle tissue decreases with age
    H A Bischoff-Ferrari
    Department of Orthopedic Surgery, University Basel, Basel, Switzerland
    J Bone Miner Res 19:265-9. 2004
    ..However, it is unknown whether VDR expression in vivo is related to age or vitamin D status, or whether VDR expression differs between skeletal muscle groups...
  8. pmc Additive benefit of higher testosterone levels and vitamin D plus calcium supplementation in regard to fall risk reduction among older men and women
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Gloriastrasse, 258091, Zurich, Switzerland
    Osteoporos Int 19:1307-14. 2008
    ..Higher physiologic testosterone levels among community dwelling older men and women may protect against falls, and this benefit may be further increased among those taking additional vitamin D plus calcium...
  9. ncbi request reprint [Effect of vitamin D on muscle strength and relevance in regard to osteoporosis prevention]
    H A Bischoff-Ferrari
    Department of Medicine, Harvard Medical School, The Robert B Brigham Arthritis and Musculoskeletal Clinical Research Center, Boston, MA 02115, USA
    Z Rheumatol 62:518-21. 2003
    ....
  10. pmc Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trial
    Heike A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Am J Clin Nutr 87:1945-51. 2008
    ..The effect of supplementation with calcium alone on risk fractures in a healthy population is not clear...
  11. ncbi request reprint Identifying a cut-off point for normal mobility: a comparison of the timed 'up and go' test in community-dwelling and institutionalised elderly women
    Heike A Bischoff
    Departments of Orthopedics and Geriatrics, University of Basel, Switzerland
    Age Ageing 32:315-20. 2003
    ..physical mobility testing is an essential component of the geriatric assessment. The timed up and go test measures basic mobility skills including a sequence of functional manoeuvres used in everyday life...
  12. ncbi request reprint Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial
    Heike A Bischoff
    Department of Orthopaedics, University of Basel, Basel, Switzerland
    J Bone Miner Res 18:343-51. 2003
    ..Over this short-term intervention, recurrent fallers seem to benefit most by the treatment. The impact of vitamin D on falls might be explained by the observed improvement in musculoskeletal function...
  13. ncbi request reprint Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials
    Heike A Bischoff-Ferrari
    Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
    JAMA 293:2257-64. 2005
    ..The role and dose of oral vitamin D supplementation in nonvertebral fracture prevention have not been well established...
  14. ncbi request reprint Is fall prevention by vitamin D mediated by a change in postural or dynamic balance?
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
    Osteoporos Int 17:656-63. 2006
    ....
  15. doi request reprint Gender-specific hip fracture risk in community-dwelling and institutionalized seniors age 65 years and older
    M Finsterwald
    Centre on Aging and Mobility, University Hospital Zurich and City Hospital Waid, Zurich, Switzerland
    Osteoporos Int 25:167-76. 2014
    ..While women have a significantly higher rate of hip fracture among the community-dwelling seniors, men have a significantly higher rate among nursing home residents...
  16. doi request reprint Before and after hip fracture, vitamin D deficiency may not be treated sufficiently
    S Maier
    Centre on Aging and Mobility, University of Zurich and Waid City Hospital, Department of Geriatrics and Aging Research, University Hospital Zurich, Gloriastrasse 25, CH 8091, Zurich, Switzerland
    Osteoporos Int 24:2765-73. 2013
    ..We further confirm the high prevalence of severe vitamin D deficiency in this population and show that those who receive supplementation have significantly higher 25-hydroxyvitamin D (25(OH)D) status...
  17. doi request reprint Mild to moderate cognitive impairment is a major risk factor for mortality and nursing home admission in the first year after hip fracture
    F Schaller
    Centre on Aging and Mobility, University of Zurich and City Hospital Waid, Zurich, Switzerland
    Bone 51:347-52. 2012
    ..It is not well established if and to what extent mild to moderate cognitive impairment predicts mortality and risk of nursing home admission after hip fracture...
  18. pmc Benefit-risk assessment of vitamin D supplementation
    H A Bischoff-Ferrari
    Centre on Aging and Mobility, Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
    Osteoporos Int 21:1121-32. 2010
    ..Current intake recommendations of 200 to 600 IU vitamin D per day may be insufficient for important disease outcomes reduced by vitamin D...
  19. doi request reprint Severe vitamin D deficiency in Swiss hip fracture patients
    H A Bischoff-Ferrari
    Department of Rheumatology, University Hospital, Zurich, Switzerland
    Bone 42:597-602. 2008
    ..Most clinical guidelines for the prevention of hip fractures recommend 800 IU vitamin D per day. This dose shifted serum 25-hydroxyvitamin D levels (25(OH)D) in previous studies to between 60 and 100 nmol/l...
  20. ncbi request reprint Responsiveness of the electronic touch screen WOMAC 3.1 OA Index in a short term clinical trial with rofecoxib
    R Theiler
    Rheumatology Clinic and Institute for Physical Medicine and Rehabilitation, Stadtspital Triemli, Zurich, Switzerland
    Osteoarthritis Cartilage 12:912-6. 2004
    ..However, whether the e-WOMAC would be suitable for monitoring the effects of drug treatment is unknown...
  21. ncbi request reprint How to select the doses of vitamin D in the management of osteoporosis
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
    Osteoporos Int 18:401-7. 2007
    ..Two main factors discussed in this review may help public health efforts to ensure desirable vitamin D levels for fall and fracture prevention, including (1) a sufficient dose of vitamin D and (2) improved adherence to supplementation...
  22. pmc Validation and patient acceptance of a computer touch screen version of the WOMAC 3.1 osteoarthritis index
    H A Bischoff-Ferrari
    Division of Rheumatology, Immunology and Allergy, Robert B Brigham and Women s Hospital, Boston, MA, USA
    Ann Rheum Dis 64:80-4. 2005
    ..To validate the WOMAC 3.1 in a touch screen computer format, which applies each question as a cartoon in writing and in speech (QUALITOUCH method), and to assess patient acceptance of the computer touch screen version...
  23. doi request reprint Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes
    Heike A Bischoff-Ferrari
    Deptartment of Rheumatology, Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Adv Exp Med Biol 624:55-71. 2008
    ..While estimates suggest that 2000 IU vitamin D3 per day may successfully and safely achieve this goal, the implications of 2000 IU or higher doses for the total adult population need to be addressed in future studies...
  24. ncbi request reprint A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study
    Kerry E Broe
    Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
    J Am Geriatr Soc 55:234-9. 2007
    ..To determine the effect of four vitamin D supplement doses on falls risk in elderly nursing home residents...
  25. ncbi request reprint A computer touch-screen version of the North American Spine Society outcome assessment instrument for the lumbar spine
    S Schaeren
    The University Hospital, Basel, Switzerland
    J Bone Joint Surg Br 87:201-4. 2005
    ..Our data indicate that the touch-screen format is comparable to the paper form. It may improve follow-up in clinical practice and research by meeting patients' preferences and minimising administrative work...
  26. ncbi request reprint Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes
    Heike A Bischoff-Ferrari
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 84:18-28. 2006
    ..The implications of higher doses for the entire adult population should be addressed in future studies...
  27. ncbi request reprint Association between serum concentrations of 25-hydroxyvitamin D and gingival inflammation
    Thomas Dietrich
    Department of Health Policy and Health Services Research, Boston University Goldman School of Dental Medicine, Boston, MA 02118, USA
    Am J Clin Nutr 82:575-80. 2005
    ..Vitamin D has been shown to have immunomodulatory effects in in vitro and in animal studies. However, data from clinical studies of inflammatory diseases are scarce...
  28. ncbi request reprint Alfacalcidol reduces the number of fallers in a community-dwelling elderly population with a minimum calcium intake of more than 500 mg daily
    Laurent Dukas
    Geriatric University Clinic, Kantonsspital, Basel, Switzerland
    J Am Geriatr Soc 52:230-6. 2004
    ..To study the effect of alfacalcidol (1alpha(OH)D3) on fall risk in community-dwelling elderly men and women...
  29. ncbi request reprint Effect of cholecalciferol plus calcium on falling in ambulatory older men and women: a 3-year randomized controlled trial
    Heike A Bischoff-Ferrari
    Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Arch Intern Med 166:424-30. 2006
    ..However, little is known about whether supplemental cholecalciferol plus calcium citrate malate will lower the long-term risk of falling in men, active older individuals, and older individuals with higher 25-hydroxyvitamin D levels...
  30. ncbi request reprint Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases, Katholieke Universiteit Leuven, Belgium, and Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Endocrinol Metab 92:1415-23. 2007
    ..which found that 700-800 IU/d vitamin D reduced hip fracture risk in elderly individuals by 25%, by defining the need for additional calcium supplementation in individuals receiving vitamin D for the prevention of hip fractures...
  31. ncbi request reprint The 25-hydroxyvitamin D threshold for better health
    Heike A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
    J Steroid Biochem Mol Biol 103:614-9. 2007
    ....
  32. ncbi request reprint Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studies
    John P Forman
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Hypertension 46:676-82. 2005
    ..We conclude that higher intake of vitamin D is not associated with a lower risk of incident hypertension...
  33. ncbi request reprint Psychosocial and geriatric correlates of functional status after total hip replacement
    H A Bischoff-Ferrari
    The Robert B Brigham Arthritis and Musculoskeletal Clinical Research Center, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Arthritis Rheum 51:829-35. 2004
    ..To determine whether psychosocial factors, chronic diseases, and common geriatric problems are associated with poor physical function 3 years after primary total hip replacement (THR)...
  34. doi request reprint Therapy of osteoporosis with calcium and vitamin D
    Bess Dawson-Hughes
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    J Bone Miner Res 22:V59-63. 2007
    ....
  35. ncbi request reprint Positive association between serum 25-hydroxyvitamin D level and bone density in osteoarthritis
    Heike A Bischoff-Ferrari
    Clinical Epidemiology Unit, Boston University, Boston, Massachusetts, USA
    Arthritis Rheum 53:821-6. 2005
    ..To describe the association between serum 25-hydroxyvitamin D (25[OH]D) level and bone mineral density (BMD) in persons with primary knee osteoarthritis (OA)...
  36. ncbi request reprint Quantitative assessment of the stops walking while talking test in the elderly
    Esther W de Hoon
    Department of Otorhinolaryngology, University Hospital, Basel, Switzerland
    Arch Phys Med Rehabil 84:838-42. 2003
    ....
  37. ncbi request reprint Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials
    Heike A Bischoff-Ferrari
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 86:1780-90. 2007
    ..The role of total calcium intake in the prevention of hip fracture risk has not been well established...
  38. ncbi request reprint Plasma 25-hydroxyvitamin D levels and risk of incident hypertension
    John P Forman
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hypertension 49:1063-9. 2007
    ..31 (95% CI: 2.03 to 2.63) in men and 1.57 (95% CI: 1.44 to 1.72) in women. Plasma 25(OH)D levels are inversely associated with risk of incident hypertension...
  39. ncbi request reprint Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US population
    Thomas Dietrich
    Department of Periodontology and the Department of Oral Surgery and Oral Radiology, Charite, Humboldt University of Berlin, Germany
    Am J Clin Nutr 80:108-13. 2004
    ..Periodontal disease (PD) is a common chronic inflammatory disease and an important risk factor for tooth loss. Vitamin D might affect periodontal disease risk via an effect on bone mineral density (BMD) or via immunomodulatory effects...
  40. ncbi request reprint Sunlight, tanning booths, and vitamin D
    Henry W Lim
    Department of Dermatology at Henry Ford Hospital, Detroit, Michigan, USA
    J Am Acad Dermatol 52:868-76. 2005