Research Topics
| H A Bischoff-FerrariSummaryAffiliation: Harvard University Country: USA Publications
| Collaborators
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Detail Information
Publications
Self-reported exercise before age 40: influence on quantitative skeletal ultrasound and fall risk in the elderlyH A Bischoff
Department of Orthopedics, University Hospital, Basel, Switzerland
Arch Phys Med Rehabil 82:801-6. 2001..To compare musculoskeletal factors with bone structure, as measured by quantitative ultrasound (QUS) at the calcaneus, and their potential to predict fall risk in geriatric inpatients...- Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 yHeike A Bischoff-Ferrari
Division of Aging, The Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
Am J Clin Nutr 80:752-8. 2004..Vitamin D may improve muscle strength through a highly specific nuclear receptor in muscle tissue... - Effect of seasonality and weather on fracture risk in individuals 65 years and olderH A Bischoff-Ferrari
Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse, 258091, Zurich, Switzerland
Osteoporos Int 18:1225-33. 2007..05 at all sites). Younger age between 65 and 80, living in warmer states and male gender were associated with increased winter morbidity due to fractures... - Where do we stand on vitamin D?Heike Annette Bischoff-Ferrari
Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
Bone 41:S13-9. 2007.... - Effect of Vitamin D on falls: a meta-analysisHeike A Bischoff-Ferrari
Division of Aging, Department of Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
JAMA 291:1999-2006. 2004..Falls among elderly individuals occur frequently, increase with age, and lead to substantial morbidity and mortality. The role of vitamin D in preventing falls among elderly people has not been well established... - Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adultsHeike A Bischoff-Ferrari
Division of Ageing, The Robert B. Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Boston, Massachusetts, USA
Am J Med 116:634-9. 2004 - Vitamin D receptor expression in human muscle tissue decreases with ageH A Bischoff-Ferrari
Department of Orthopedic Surgery, University Basel, Basel, Switzerland
J Bone Miner Res 19:265-9. 2004..However, it is unknown whether VDR expression in vivo is related to age or vitamin D status, or whether VDR expression differs between skeletal muscle groups... 
Additive benefit of higher testosterone levels and vitamin D plus calcium supplementation in regard to fall risk reduction among older men and womenH A Bischoff-Ferrari
Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Gloriastrasse, 258091, Zurich, Switzerland
Osteoporos Int 19:1307-14. 2008..Higher physiologic testosterone levels among community dwelling older men and women may protect against falls, and this benefit may be further increased among those taking additional vitamin D plus calcium...- [Effect of vitamin D on muscle strength and relevance in regard to osteoporosis prevention]H A Bischoff-Ferrari
Department of Medicine, Harvard Medical School, The Robert B Brigham Arthritis and Musculoskeletal Clinical Research Center, Boston, MA 02115, USA
Z Rheumatol 62:518-21. 2003.... - Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trialHeike A Bischoff-Ferrari
Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
Am J Clin Nutr 87:1945-51. 2008..The effect of supplementation with calcium alone on risk fractures in a healthy population is not clear... - Identifying a cut-off point for normal mobility: a comparison of the timed 'up and go' test in community-dwelling and institutionalised elderly womenHeike A Bischoff
Departments of Orthopedics and Geriatrics, University of Basel, Switzerland
Age Ageing 32:315-20. 2003..physical mobility testing is an essential component of the geriatric assessment. The timed up and go test measures basic mobility skills including a sequence of functional manoeuvres used in everyday life... - Effects of vitamin D and calcium supplementation on falls: a randomized controlled trialHeike A Bischoff
Department of Orthopaedics, University of Basel, Basel, Switzerland
J Bone Miner Res 18:343-51. 2003..Over this short-term intervention, recurrent fallers seem to benefit most by the treatment. The impact of vitamin D on falls might be explained by the observed improvement in musculoskeletal function... - Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trialsHeike A Bischoff-Ferrari
Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
JAMA 293:2257-64. 2005..The role and dose of oral vitamin D supplementation in nonvertebral fracture prevention have not been well established... - Is fall prevention by vitamin D mediated by a change in postural or dynamic balance?H A Bischoff-Ferrari
Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
Osteoporos Int 17:656-63. 2006.... 
Mild to moderate cognitive impairment is a major risk factor for mortality and nursing home admission in the first year after hip fractureF Schaller
Centre on Aging and Mobility, University of Zurich and City Hospital Waid, Zurich, Switzerland
Bone 51:347-52. 2012..It is not well established if and to what extent mild to moderate cognitive impairment predicts mortality and risk of nursing home admission after hip fracture...- Severe vitamin D deficiency in Swiss hip fracture patientsH A Bischoff-Ferrari
Department of Rheumatology, University Hospital, Zurich, Switzerland
Bone 42:597-602. 2008..Most clinical guidelines for the prevention of hip fractures recommend 800 IU vitamin D per day. This dose shifted serum 25-hydroxyvitamin D levels (25(OH)D) in previous studies to between 60 and 100 nmol/l... - Benefit-risk assessment of vitamin D supplementationH A Bischoff-Ferrari
Centre on Aging and Mobility, Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
Osteoporos Int 21:1121-32. 2010..Current intake recommendations of 200 to 600 IU vitamin D per day may be insufficient for important disease outcomes reduced by vitamin D... - Responsiveness of the electronic touch screen WOMAC 3.1 OA Index in a short term clinical trial with rofecoxibR Theiler
Rheumatology Clinic and Institute for Physical Medicine and Rehabilitation, Stadtspital Triemli, Zurich, Switzerland
Osteoarthritis Cartilage 12:912-6. 2004..However, whether the e-WOMAC would be suitable for monitoring the effects of drug treatment is unknown... - Validation and patient acceptance of a computer touch screen version of the WOMAC 3.1 osteoarthritis indexH A Bischoff-Ferrari
Division of Rheumatology, Immunology and Allergy, Robert B Brigham and Women s Hospital, Boston, MA, USA
Ann Rheum Dis 64:80-4. 2005..To validate the WOMAC 3.1 in a touch screen computer format, which applies each question as a cartoon in writing and in speech (QUALITOUCH method), and to assess patient acceptance of the computer touch screen version... - How to select the doses of vitamin D in the management of osteoporosisH A Bischoff-Ferrari
Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
Osteoporos Int 18:401-7. 2007..Two main factors discussed in this review may help public health efforts to ensure desirable vitamin D levels for fall and fracture prevention, including (1) a sufficient dose of vitamin D and (2) improved adherence to supplementation... - A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose studyKerry E Broe
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 55:234-9. 2007..To determine the effect of four vitamin D supplement doses on falls risk in elderly nursing home residents... - Optimal serum 25-hydroxyvitamin D levels for multiple health outcomesHeike A Bischoff-Ferrari
Deptartment of Rheumatology, Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
Adv Exp Med Biol 624:55-71. 2008..While estimates suggest that 2000 IU vitamin D3 per day may successfully and safely achieve this goal, the implications of 2000 IU or higher doses for the total adult population need to be addressed in future studies... - A computer touch-screen version of the North American Spine Society outcome assessment instrument for the lumbar spineS Schaeren
The University Hospital, Basel, Switzerland
J Bone Joint Surg Br 87:201-4. 2005..Our data indicate that the touch-screen format is comparable to the paper form. It may improve follow-up in clinical practice and research by meeting patients' preferences and minimising administrative work... - Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomesHeike A Bischoff-Ferrari
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 84:18-28. 2006..The implications of higher doses for the entire adult population should be addressed in future studies... - Association between serum concentrations of 25-hydroxyvitamin D and gingival inflammationThomas Dietrich
Department of Health Policy and Health Services Research, Boston University Goldman School of Dental Medicine, Boston, MA 02118, USA
Am J Clin Nutr 82:575-80. 2005..Vitamin D has been shown to have immunomodulatory effects in in vitro and in animal studies. However, data from clinical studies of inflammatory diseases are scarce... - Alfacalcidol reduces the number of fallers in a community-dwelling elderly population with a minimum calcium intake of more than 500 mg dailyLaurent Dukas
Geriatric University Clinic, Kantonsspital, Basel, Switzerland
J Am Geriatr Soc 52:230-6. 2004..To study the effect of alfacalcidol (1alpha(OH)D3) on fall risk in community-dwelling elderly men and women... - Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studiesJohn P Forman
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Hypertension 46:676-82. 2005..We conclude that higher intake of vitamin D is not associated with a lower risk of incident hypertension... - Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trialsSteven Boonen
Leuven University Center for Metabolic Bone Diseases, Katholieke Universiteit Leuven, Belgium, and Brigham and Women s Hospital, Boston, MA 02115, USA
J Clin Endocrinol Metab 92:1415-23. 2007..which found that 700-800 IU/d vitamin D reduced hip fracture risk in elderly individuals by 25%, by defining the need for additional calcium supplementation in individuals receiving vitamin D for the prevention of hip fractures... - The 25-hydroxyvitamin D threshold for better healthHeike A Bischoff-Ferrari
Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
J Steroid Biochem Mol Biol 103:614-9. 2007.... - Effect of cholecalciferol plus calcium on falling in ambulatory older men and women: a 3-year randomized controlled trialHeike A Bischoff-Ferrari
Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Zurich, Switzerland
Arch Intern Med 166:424-30. 2006..However, little is known about whether supplemental cholecalciferol plus calcium citrate malate will lower the long-term risk of falling in men, active older individuals, and older individuals with higher 25-hydroxyvitamin D levels... - Psychosocial and geriatric correlates of functional status after total hip replacementH A Bischoff-Ferrari
The Robert B Brigham Arthritis and Musculoskeletal Clinical Research Center, Brigham and Women s Hospital, Boston, Massachusetts, USA
Arthritis Rheum 51:829-35. 2004..To determine whether psychosocial factors, chronic diseases, and common geriatric problems are associated with poor physical function 3 years after primary total hip replacement (THR)... - Therapy of osteoporosis with calcium and vitamin DBess Dawson Hughes
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
J Bone Miner Res 22:V59-63. 2007.... - Positive association between serum 25-hydroxyvitamin D level and bone density in osteoarthritisHeike A Bischoff-Ferrari
Clinical Epidemiology Unit, Boston University, Boston, Massachusetts, USA
Arthritis Rheum 53:821-6. 2005..To describe the association between serum 25-hydroxyvitamin D (25[OH]D) level and bone mineral density (BMD) in persons with primary knee osteoarthritis (OA)... - Quantitative assessment of the stops walking while talking test in the elderlyEsther W de Hoon
Department of Otorhinolaryngology, University Hospital, Basel, Switzerland
Arch Phys Med Rehabil 84:838-42. 2003.... - Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trialsHeike A Bischoff-Ferrari
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 86:1780-90. 2007..The role of total calcium intake in the prevention of hip fracture risk has not been well established... - Plasma 25-hydroxyvitamin D levels and risk of incident hypertensionJohn P Forman
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Hypertension 49:1063-9. 2007..31 (95% CI: 2.03 to 2.63) in men and 1.57 (95% CI: 1.44 to 1.72) in women. Plasma 25(OH)D levels are inversely associated with risk of incident hypertension... - Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US populationThomas Dietrich
Department of Periodontology and the Department of Oral Surgery and Oral Radiology, Charite, Humboldt University of Berlin, Germany
Am J Clin Nutr 80:108-13. 2004..Periodontal disease (PD) is a common chronic inflammatory disease and an important risk factor for tooth loss. Vitamin D might affect periodontal disease risk via an effect on bone mineral density (BMD) or via immunomodulatory effects... - Sunlight, tanning booths, and vitamin DHenry W Lim
Department of Dermatology at Henry Ford Hospital, Detroit, Michigan, USA
J Am Acad Dermatol 52:868-76. 2005