Temugin Berta

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Acute morphine activates satellite glial cells and up-regulates IL-1β in dorsal root ganglia in mice via matrix metalloprotease-9
    Temugin Berta
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Mol Pain 8:18. 2012
  2. pmc TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice
    Tong Liu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Clin Invest 122:2195-207. 2012
  3. pmc Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma
    Zhen Zhong Xu
    Pain Signaling and Plasticity Laboratory, Department of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Ann Neurol 74:490-5. 2013
  4. pmc TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2
    Ling Zhang
    Department of Anesthesiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Pain 152:419-27. 2011
  5. pmc Microglia and spinal cord synaptic plasticity in persistent pain
    Sarah Taves
    Pain Signaling and Plasticity Laboratory, Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Neural Plast 2013:753656. 2013
  6. pmc Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury
    Zhen Zhong Xu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Neuroimmune Pharmacol 8:37-41. 2013
  7. pmc Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice
    Yen Chin Liu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Pain 8:19. 2012
  8. pmc Toll-like receptor 7 mediates pruritus
    Tong Liu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Neurosci 13:1460-2. 2010
  9. pmc Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions
    Zhen Zhong Xu
    Department of Anesthesiology, Sensory Plasticity Laboratory, Pain Research Center, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Med 16:592-7, 1p following 597. 2010

Collaborators

Detail Information

Publications9

  1. pmc Acute morphine activates satellite glial cells and up-regulates IL-1β in dorsal root ganglia in mice via matrix metalloprotease-9
    Temugin Berta
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Mol Pain 8:18. 2012
    ..We examined acute morphine-induced activation of satellite glial cells (SGCs) and up-regulation of IL-1β in dorsal root ganglia (DRGs), and further investigated the involvement of MMP-9 in these opioid-induced peripheral changes...
  2. pmc TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice
    Tong Liu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Clin Invest 122:2195-207. 2012
    ..Our findings demonstrate a critical role of TLR3 in regulating sensory neuronal excitability, spinal cord synaptic transmission, and central sensitization. TLR3 may serve as a new target for developing anti-itch treatment...
  3. pmc Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma
    Zhen Zhong Xu
    Pain Signaling and Plasticity Laboratory, Department of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Ann Neurol 74:490-5. 2013
    ..Thus, NPD1/PD1 and related mimetics might serve as a new class of analgesics for preventing and treating neuropathic pain...
  4. pmc TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2
    Ling Zhang
    Department of Anesthesiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Pain 152:419-27. 2011
    ..TNF-α is shown to play a critical role in regulating spinal cord synaptic plasticity and central sensitization, and TNFR1 and TNFR2 play a distinct role in regulating different phases of inflammatory pain...
  5. pmc Microglia and spinal cord synaptic plasticity in persistent pain
    Sarah Taves
    Pain Signaling and Plasticity Laboratory, Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Neural Plast 2013:753656. 2013
    ..Insights into microglial-neuronal interactions in the spinal cord dorsal horn will not only further our understanding of neural plasticity but may also lead to novel therapeutics for chronic pain management...
  6. pmc Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury
    Zhen Zhong Xu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Neuroimmune Pharmacol 8:37-41. 2013
    ..Our data suggest that RvE1 may attenuate neuropathic pain via inhibiting microglial signaling. Targeting the anti-inflammatory and pro-resolution lipid mediators may offer new options for preventing and treating neuropathic pain...
  7. pmc Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice
    Yen Chin Liu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Pain 8:19. 2012
    ..We examined MMP-9 expression and localization in dorsal root ganglia (DRGs) after acute morphine treatment and, furthermore, the role of MMP-9 in modulating acute morphine-induced analgesia and hyperalgesia in mice...
  8. pmc Toll-like receptor 7 mediates pruritus
    Tong Liu
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Neurosci 13:1460-2. 2010
    ..Our results indicate that TLR7 mediates itching and is a potential therapeutic target for anti-itch treatment in skin disease conditions...
  9. pmc Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions
    Zhen Zhong Xu
    Department of Anesthesiology, Sensory Plasticity Laboratory, Pain Research Center, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Med 16:592-7, 1p following 597. 2010
    ..Given the potency of resolvins and the well-known side effects of opioids and COX inhibitors, resolvins may represent new analgesics for treating inflammatory pain...