Sabina Berretta

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Extracellular matrix abnormalities in schizophrenia
    Sabina Berretta
    Translational Neuroscience Laboratory, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Neuropharmacology 62:1584-97. 2012
  2. ncbi request reprint Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophrenia
    Sabina Berretta
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 62:884-93. 2007
  3. pmc Infralimbic cortex activation increases c-Fos expression in intercalated neurons of the amygdala
    S Berretta
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, MA 02478, USA
    Neuroscience 132:943-53. 2005
  4. ncbi request reprint Cortico-amygdala circuits: role in the conditioned stress response
    Sabina Berretta
    Harvard Medical School, Department of Psychiatry, 25 Shattuck Street, Boston, Massachusetts 02115, USA
    Stress 8:221-32. 2005
  5. doi request reprint Extracellular matrix-glial abnormalities in the amygdala and entorhinal cortex of subjects diagnosed with schizophrenia
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA
    Arch Gen Psychiatry 67:155-66. 2010
  6. doi request reprint A rodent model of schizophrenia derived from postmortem studies
    Sabina Berretta
    Program in Structural and Molecular Neuroscience and Laboratory for Translational Neuroscience, McLean Hospital, Belmont, MA, United States
    Behav Brain Res 204:363-8. 2009
  7. ncbi request reprint The amygdala modulates neuronal activation in the hippocampus in response to spatial novelty
    Archana Sheth
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    Hippocampus 18:169-81. 2008
  8. ncbi request reprint Long-term effects of amygdala GABA receptor blockade on specific subpopulations of hippocampal interneurons
    Sabina Berretta
    Program for Structural and Molecular Neuroscience, McLean Hospital, Belmont, Massachusetts 02478, USA
    Hippocampus 14:876-94. 2004
  9. pmc Parvalbumin neurons in the entorhinal cortex of subjects diagnosed with bipolar disorder or schizophrenia
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 61:640-52. 2007
  10. pmc Subpopulations of neurons expressing parvalbumin in the human amygdala
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, MA 02478, USA
    J Comp Neurol 496:706-22. 2006

Collaborators

Detail Information

Publications14

  1. pmc Extracellular matrix abnormalities in schizophrenia
    Sabina Berretta
    Translational Neuroscience Laboratory, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Neuropharmacology 62:1584-97. 2012
    ....
  2. ncbi request reprint Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophrenia
    Sabina Berretta
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 62:884-93. 2007
    ..Growing evidence supports a pivotal role for the amygdala in the pathogenesis of bipolar disorder (BD) and schizophrenia (SZ). However, the occurrence of morphologic changes in the amygdala is currently controversial...
  3. pmc Infralimbic cortex activation increases c-Fos expression in intercalated neurons of the amygdala
    S Berretta
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, MA 02478, USA
    Neuroscience 132:943-53. 2005
    ..Thus, our findings raise the possibility that the infralimbic cortex inhibits conditioned fear via the excitation of intercalated cells and the consequent inhibition of central amygdala neurons...
  4. ncbi request reprint Cortico-amygdala circuits: role in the conditioned stress response
    Sabina Berretta
    Harvard Medical School, Department of Psychiatry, 25 Shattuck Street, Boston, Massachusetts 02115, USA
    Stress 8:221-32. 2005
    ..Within the scope of this review, current evidence relative to the interaction between the amygdala and cortical networks will be considered in relationship to the integration of the conditioned response to stress...
  5. doi request reprint Extracellular matrix-glial abnormalities in the amygdala and entorhinal cortex of subjects diagnosed with schizophrenia
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA
    Arch Gen Psychiatry 67:155-66. 2010
    ....
  6. doi request reprint A rodent model of schizophrenia derived from postmortem studies
    Sabina Berretta
    Program in Structural and Molecular Neuroscience and Laboratory for Translational Neuroscience, McLean Hospital, Belmont, MA, United States
    Behav Brain Res 204:363-8. 2009
    ....
  7. ncbi request reprint The amygdala modulates neuronal activation in the hippocampus in response to spatial novelty
    Archana Sheth
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    Hippocampus 18:169-81. 2008
    ..These findings also raise the possibility that amygdala abnormalities may contribute to impairments in cognitive information processing in subjects with major psychoses...
  8. ncbi request reprint Long-term effects of amygdala GABA receptor blockade on specific subpopulations of hippocampal interneurons
    Sabina Berretta
    Program for Structural and Molecular Neuroscience, McLean Hospital, Belmont, Massachusetts 02478, USA
    Hippocampus 14:876-94. 2004
    ..These similarities suggest that, in this disease, a disruption of GABAergic transmission within the amygdala may play a significant role in the induction of abnormalities in the hippocampus...
  9. pmc Parvalbumin neurons in the entorhinal cortex of subjects diagnosed with bipolar disorder or schizophrenia
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 61:640-52. 2007
    ..These neurons play a pivotal role within ECx intrinsic circuits...
  10. pmc Subpopulations of neurons expressing parvalbumin in the human amygdala
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, MA 02478, USA
    J Comp Neurol 496:706-22. 2006
    ..Such properties suggest that each of these neuronal subpopulations may play a specific role within the intrinsic circuitry of the amygdala...
  11. ncbi request reprint A rat model for neural circuitry abnormalities in schizophrenia
    Sabina Berretta
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Protoc 1:833-9. 2006
    ..This has established the construct and predictive validity of this model for studying limbic-lobe circuitry abnormalities. We propose that this modeling strategy may provide a valid alternative to isomorphic models of these diseases...
  12. pmc Total number, distribution, and phenotype of cells expressing chondroitin sulfate proteoglycans in the normal human amygdala
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, MA 02478, USA
    Brain Res 1207:84-95. 2008
    ..These results suggest that astrocytes are the main cell type expressing CSPGs in the adult human amygdala. Their highly segregated distribution pattern suggests that these cells serve specialized functions within human amygdalar nuclei...
  13. pmc Developmental pattern of perineuronal nets in the human prefrontal cortex and their deficit in schizophrenia
    Sarah A Mauney
    Laboratory of Cellular Neuropathology, McLean Hospital, Belmont
    Biol Psychiatry 74:427-35. 2013
    ..They regulate the postnatal experience-dependent maturation of brain circuits and maintain their functional integrity in the mature brain by stabilizing their synaptic architecture...
  14. ncbi request reprint DNA fragmentation decreased in schizophrenia but not bipolar disorder
    Francine M Benes
    Laboratories for Structural Neuroscience, McLean Hospital, Belmont, MA 02478, USA
    Arch Gen Psychiatry 60:359-64. 2003
    ..Apoptosis is thought to play a role in neuronal pathology in schizophrenia and bipolar disorder...

Research Grants14

  1. Amygdalar and Thalamic Abnormalities in Schizophrenia
    Sabina Berretta; Fiscal Year: 2002
    ....
  2. Cortico-Amygdalo-Thalamic Circuitry in Humans
    Sabina Berretta; Fiscal Year: 2007
    ..More in general, results obtained from the investigations described in this proposal will be relevant to the study of the physiological functions of AMYG and of its role in major psychiatric diseases. ..
  3. 'Partial' Rodent Model for GABA Defect in Schizophrenia
    Sabina Berretta; Fiscal Year: 2007
    ..The significance of these studies resides in their potential of providing functional links between neurochemical abnormalities in schizophrenia detected in interconnected limbic brain regions. ..
  4. Supplement/'Partial' Rodent Model for GABA Defect in Schizophrenia/MH 066280
    Sabina Berretta; Fiscal Year: 2006
    ..N. Lange, a Biostatistician at McLean Hospital. In summary, the funding here requested will greatly improve the productivity of this laboratory and ensure that the currently funded projects will be brought to a timely completion. ..
  5. Disruption of Extracellular Matrix-Glial Interactions in Schizophrenia
    Sabina Berretta; Fiscal Year: 2011
    ....