T Benner

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Evaluating effects of normobaric oxygen therapy in acute stroke with MRI-based predictive models
    Ona Wu
    Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston MA 02114, USA
    Med Gas Res 2:5. 2012
  2. ncbi request reprint Real-time RF pulse adjustment for B0 drift correction
    Thomas Benner
    Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 56:204-9. 2006
  3. ncbi request reprint Comparison of manual and automatic section positioning of brain MR images
    Thomas Benner
    Department of Radiology and General Clinical Research Center, Massachusetts General Hospital, Athinoula A Martinos Center, Harvard Medical School, 149 13th St, Rm 2301, Charlestown, MA 02129, USA
    Radiology 239:246-54. 2006
  4. pmc Diffusion imaging with prospective motion correction and reacquisition
    Thomas Benner
    Department of Radiology, Athinoula A Martinos Center, Charlestown, Massachusetts, USA
    Magn Reson Med 66:154-67. 2011
  5. ncbi request reprint Cerebral MR perfusion imaging: first clinical application of a 1 M gadolinium chelate (Gadovist 1.0) in a double-blinded randomized dose-finding study
    T Benner
    Department of Neuroradiology, University of Heidelberg Medical School, D 69120 Heidelberg, Germany
    J Magn Reson Imaging 12:371-80. 2000
  6. ncbi request reprint Accuracy of gamma-variate fits to concentration-time curves from dynamic susceptibility-contrast enhanced MRI: influence of time resolution, maximal signal drop and signal-to-noise
    T Benner
    Department of Neuroradiology, University of Heidelberg Medical School, Germany
    Magn Reson Imaging 15:307-17. 1997
  7. pmc A score to predict early risk of recurrence after ischemic stroke
    H Ay
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Neurology 74:128-35. 2010
  8. ncbi request reprint Reducing motion artefacts in diffusion-weighted MRI of the brain: efficacy of navigator echo correction and pulse triggering
    O Dietrich
    Department of Neuroradiology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Neuroradiology 42:85-91. 2000
  9. ncbi request reprint Does the "keyhole" technique improve spatial resolution in MRI perfusion measurements? A study in volunteers
    S Heiland
    Department of Neuroradiology, University of Heidelberg Medical School, Germany
    Neuroradiology 43:518-24. 2001
  10. ncbi request reprint Simultaneous assessment of cerebral hemodynamics and contrast agent uptake in lesions with disrupted blood-brain-barrier
    S Heiland
    Department of Neuroradiology, University of Heidelberg Medical School, Germany
    Magn Reson Imaging 17:21-7. 1999

Detail Information

Publications50

  1. pmc Evaluating effects of normobaric oxygen therapy in acute stroke with MRI-based predictive models
    Ona Wu
    Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston MA 02114, USA
    Med Gas Res 2:5. 2012
    ..abstract:..
  2. ncbi request reprint Real-time RF pulse adjustment for B0 drift correction
    Thomas Benner
    Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 56:204-9. 2006
    ..The proposed method corrects for apparent image shift and ensures continuously effective fat saturation over the duration of an acquisition...
  3. ncbi request reprint Comparison of manual and automatic section positioning of brain MR images
    Thomas Benner
    Department of Radiology and General Clinical Research Center, Massachusetts General Hospital, Athinoula A Martinos Center, Harvard Medical School, 149 13th St, Rm 2301, Charlestown, MA 02129, USA
    Radiology 239:246-54. 2006
    ..001). Automatic section prescription leads to improved reproducibility of imaging orientations for intra- and intersubject series in clinical practice...
  4. pmc Diffusion imaging with prospective motion correction and reacquisition
    Thomas Benner
    Department of Radiology, Athinoula A Martinos Center, Charlestown, Massachusetts, USA
    Magn Reson Med 66:154-67. 2011
    ..The presented method allows the reduction of two types of common motion related artifacts at the cost of slightly increased acquisition time...
  5. ncbi request reprint Cerebral MR perfusion imaging: first clinical application of a 1 M gadolinium chelate (Gadovist 1.0) in a double-blinded randomized dose-finding study
    T Benner
    Department of Neuroradiology, University of Heidelberg Medical School, D 69120 Heidelberg, Germany
    J Magn Reson Imaging 12:371-80. 2000
    ..3 mmol/kg as the diagnostically adequate dose given the gradient-echo sequence and field strength used. Gadovist 1.0 has been shown to be a safe and well-tolerated contrast agent. J. Magn. Reson. Imaging 2000;12:371-380...
  6. ncbi request reprint Accuracy of gamma-variate fits to concentration-time curves from dynamic susceptibility-contrast enhanced MRI: influence of time resolution, maximal signal drop and signal-to-noise
    T Benner
    Department of Neuroradiology, University of Heidelberg Medical School, Germany
    Magn Reson Imaging 15:307-17. 1997
    ..This is more important the lower SNR is. The shown dependencies should be taken into account when choosing MR sequence parameters and application of contrast media...
  7. pmc A score to predict early risk of recurrence after ischemic stroke
    H Ay
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Neurology 74:128-35. 2010
    ..There is currently no instrument to stratify patients presenting with ischemic stroke according to early risk of recurrent stroke. We sought to develop a comprehensive prognostic score to predict 90-day risk of recurrent stroke...
  8. ncbi request reprint Reducing motion artefacts in diffusion-weighted MRI of the brain: efficacy of navigator echo correction and pulse triggering
    O Dietrich
    Department of Neuroradiology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Neuroradiology 42:85-91. 2000
    ..Pulse triggering and navigator echo correction significantly improve image quality and provide a technique for high-quality DWI on standard imagers without improved gradient hardware...
  9. ncbi request reprint Does the "keyhole" technique improve spatial resolution in MRI perfusion measurements? A study in volunteers
    S Heiland
    Department of Neuroradiology, University of Heidelberg Medical School, Germany
    Neuroradiology 43:518-24. 2001
    ..However, it should be applied carefully, because the spatial resolution of the dynamic signal change and the cerebrovascular parameters is less than that afforded by the spatial resolution of the reconstructed images...
  10. ncbi request reprint Simultaneous assessment of cerebral hemodynamics and contrast agent uptake in lesions with disrupted blood-brain-barrier
    S Heiland
    Department of Neuroradiology, University of Heidelberg Medical School, Germany
    Magn Reson Imaging 17:21-7. 1999
    ..This method may be a useful tool for characterizing, staging, and therapy monitoring of brain tumors...
  11. pmc T₂* mapping and B₀ orientation-dependence at 7 T reveal cyto- and myeloarchitecture organization of the human cortex
    J Cohen-Adad
    A A Martinos Center for Biomedical Imaging, Dept of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 60:1006-14. 2012
    ....
  12. ncbi request reprint Perfusion-weighted magnetic resonance imaging in patients with carotid artery disease before and after carotid endarterectomy
    A Doerfler
    Department of Neuroradiology, University of Essen Medical School, Germany
    J Vasc Surg 34:587-93. 2001
    ....
  13. doi request reprint In vivo evidence of disseminated subpial T2* signal changes in multiple sclerosis at 7 T: a surface-based analysis
    J Cohen-Adad
    AA Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 57:55-62. 2011
    ..Our data support the presence of disseminated subpial increases in T2* signal in subjects with MS, which may reflect the diffuse subpial pathology described in neuropathology...
  14. ncbi request reprint Automated perfusion-weighted MRI using localized arterial input functions
    Cory Lorenz
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Division of Health Sciences and Technology, Harvard MIT, Charlestown, Massachusetts 08129, USA
    J Magn Reson Imaging 24:1133-9. 2006
    ....
  15. ncbi request reprint Frontal connections and cognitive changes in normal aging rhesus monkeys: a DTI study
    Nikos Makris
    Harvard Medical School Department of Neurology, Center for Morphometric Analysis, Massachusetts General Hospital, Boston, MA 02129, United States
    Neurobiol Aging 28:1556-67. 2007
    ..To our knowledge this is the first investigation reporting such alterations in the aging monkey...
  16. ncbi request reprint Real-time rigid body motion correction and shimming using cloverleaf navigators
    Andre J W van der Kouwe
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 56:1019-32. 2006
    ..Correction for between-scan motion can be accomplished by using the same reference map for each scan repetition. Human and phantom tests demonstrated a consistent improvement in image quality if motion occurred during the acquisition...
  17. pmc Fast multislice pH-weighted chemical exchange saturation transfer (CEST) MRI with Unevenly segmented RF irradiation
    Phillip Zhe Sun
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 65:588-94. 2011
    ..In sum, a fast multislice relaxation self-compensated CEST MRI sequence was developed, with significantly improved sensitivity and suitable for in vivo applications...
  18. pmc Early time points perfusion imaging
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 54:1070-82. 2011
    ..A recipe to run ET was presented, with attention paid to the noise problem around the time of arrival (TOA) of the contrast agent...
  19. pmc Toward implementing an MRI-based PET attenuation-correction method for neurologic studies on the MR-PET brain prototype
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Nucl Med 51:1431-8. 2010
    ....
  20. pmc Brain morphometry with multiecho MPRAGE
    Andre J W van der Kouwe
    Department of Radiology, Massachusetts General Hospital, Athinoula A Martinos Center for Biomedical Imaging, Harvard Medical School, Charlestown, MA 02129, USA
    Neuroimage 40:559-69. 2008
    ..Since acquisition time is the same for MEMPR as for MPRAGE, and it has better distortion properties and additional T2* information, MEMPR is recommended for morphometry studies...
  21. pmc Model-based segmentation of hippocampal subfields in ultra-high resolution in vivo MRI
    Koen Van Leemput
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, MGH, Harvard Medical School, USA
    Med Image Comput Comput Assist Interv 11:235-43. 2008
    ..We validate the proposed technique by comparing our segmentation results with corresponding manual delineations in ultra-high resolution MRI scans of five individuals...
  22. pmc Investigation of optimizing and translating pH-sensitive pulsed-chemical exchange saturation transfer (CEST) imaging to a 3T clinical scanner
    Phillip Zhe Sun
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Department of Radiology and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 60:834-41. 2008
    ..9 ppm). Furthermore, pilot endogenous APT imaging of normal human volunteers was demonstrated, warranting future APT MRI of stroke patients to elucidate its diagnostic value...
  23. pmc Automated segmentation of hippocampal subfields from ultra-high resolution in vivo MRI
    Koen Van Leemput
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Hippocampus 19:549-57. 2009
    ..Unlike manual segmentations, our automated technique is fully reproducible, and fast enough to enable routine analysis of the hippocampal subfields in large imaging studies...
  24. pmc Early experience of translating pH-weighted MRI to image human subjects at 3 Tesla
    Phillip Zhe Sun
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Mass 02129, USA
    Stroke 41:S147-51. 2010
    ..Tissue pH, a well-regulated physiological index that alters on disrupted tissue metabolism, may provide a surrogate metabolic imaging marker that augments the DWI and PWI for penumbra imaging...
  25. ncbi request reprint Motor recovery and cortical reorganization after constraint-induced movement therapy in stroke patients: a preliminary study
    Judith D Schaechter
    Massachusetts General Hospital NMR Center, Department of Radiology, Charlestown, MA 02129, USA
    Neurorehabil Neural Repair 16:326-38. 2002
    ..These data provide preliminary evidence that gains in motor function produced by CIMT in chronic stroke patients may be associated with a shift in laterality of motor cortical activation toward the undamaged hemisphere...
  26. pmc Comatose patients with cardiac arrest: predicting clinical outcome with diffusion-weighted MR imaging
    Ona Wu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149 13th St, CNY 2301, Charlestown, MA 02129, USA
    Radiology 252:173-81. 2009
    ..To examine whether the severity and spatial distribution of reductions in apparent diffusion coefficient (ADC) are associated with clinical outcomes in patients who become comatose after cardiac arrest...
  27. ncbi request reprint Tracer arrival timing-insensitive technique for estimating flow in MR perfusion-weighted imaging using singular value decomposition with a block-circulant deconvolution matrix
    Ona Wu
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School, Boston, Massachusetts 02129, USA
    Magn Reson Med 50:164-74. 2003
    ..Shift maps can continue to provide a sensitive reflection of disturbed hemodynamics...
  28. pmc MRI-assisted PET motion correction for neurologic studies in an integrated MR-PET scanner
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Nucl Med 52:154-61. 2011
    ..In this work, a novel algorithm for data processing and rigid-body motion correction (MC) for the MRI-compatible BrainPET prototype scanner is described, and proof-of-principle phantom and human studies are presented...
  29. ncbi request reprint On-line automatic slice positioning for brain MR imaging
    Andre J W van der Kouwe
    Department of Radiology, MGH, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Neuroimage 27:222-30. 2005
    ..Translations and rotations relative to the atlas can be set so that planning can be done in anatomical space, rather than scanner coordinates, and stored as part of the protocol allowing standardization of slice orientations...
  30. ncbi request reprint Strategies for improving the detection of fMRI activation in trigeminal pathways with cardiac gating
    Wei Ting Zhang
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, and Harvard Medical School, Bldg 149 2301, 13th Street, Charlestown, MA 02129, USA
    Neuroimage 31:1506-12. 2006
    ..Activation in the brainstem and the thalamus was best detected by cardiac-gated dual-echo EPI...
  31. ncbi request reprint White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging
    David H Salat
    Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Mass 02129 2060, USA
    Stroke 37:1759-64. 2006
    ..We used diffusion tensor imaging to evaluate the anatomic distribution of white matter degeneration in participants diagnosed with advanced CAA...
  32. doi request reprint Halving imaging time of whole brain diffusion spectrum imaging and diffusion tractography using simultaneous image refocusing in EPI
    Timothy G Reese
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Magn Reson Imaging 29:517-22. 2009
    ....
  33. pmc In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI
    Caterina Mainero
    Athinoula Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA
    Neurology 73:941-8. 2009
    ....
  34. doi request reprint Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers
    V J Wedeen
    Department of Radiology, MGH Martinos Center for Biomedical Imaging, Harvard Medical School, Charlestown, MA 02129, USA
    Neuroimage 41:1267-77. 2008
    ..These findings indicate that DSI tractography is able to image crossing fibers in neural tissue, an essential step toward non-invasive imaging of connectional neuroanatomy...
  35. pmc The Causative Classification of Stroke system: an international reliability and optimization study
    E M Arsava
    A A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Neurology 75:1277-84. 2010
    ..We determined whether CCS demonstrates high interrater reliability in order to be useful for international multicenter studies...
  36. ncbi request reprint Conversion of ischemic brain tissue into infarction increases with age
    Hakan Ay
    The AA Martinos Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Stroke 36:2632-6. 2005
    ..We hypothesize that age is a marker for tissue susceptibility to ischemia and thus plays a role in determining tissue outcome in human stroke...
  37. ncbi request reprint Neuroanatomic correlates of stroke-related myocardial injury
    H Ay
    A A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Neurology 66:1325-9. 2006
    ..Myocardial injury can occur after ischemic stroke in the absence of primary cardiac causes. The neuroanatomic basis of stroke-related myocardial injury is not well understood...
  38. ncbi request reprint A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System
    Hakan Ay
    AA Martinos Center for Biomedical Imaging and Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 2301, Charlestown, MA 02129, USA
    Stroke 38:2979-84. 2007
    ..In this article, we present an automated version of the SSS-TOAST, the Causative Classification System (CCS), to facilitate its utility in multicenter settings...
  39. ncbi request reprint Perfusion- and diffusion-weighted magnetic resonance imaging for monitoring decompressive craniectomy in animals with experimental hemispheric stroke
    Arnd Doerfler
    Department of Neuroradiology, University of Essen Medical School, Germany
    J Neurosurg 96:933-40. 2002
    ..The aim of this study was to use two types of serial magnetic resonance (MR) imaging-perfusion-weighted (PW) and diffusion-weighted (DW)-to monitor craniectomy in rats with hemispheric stroke...
  40. ncbi request reprint Effect of using local arterial input functions on cerebral blood flow estimation
    Cory Lorenz
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Magn Reson Imaging 24:57-65. 2006
    ....
  41. ncbi request reprint Transient ischemic attack with infarction: a unique syndrome?
    Hakan Ay
    Department of A A Martinos Center for Biomedical Imaging and Stroke Service, Department of Radiology, Boston, MA 02129, USA
    Ann Neurol 57:679-86. 2005
    ..3% in those with ischemic stroke. TIA with infarction appears to have unique features separate from TIA without infarction and ischemic stroke. We propose identifying TSI as a separate clinical syndrome with distinct prognostic features...
  42. doi request reprint Associating the mesoscale fiber organization of the tongue with local strain rate during swallowing
    Samuel M Felton
    Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    J Biomech 41:1782-9. 2008
    ..These data demonstrate that lingual deformation during swallowing involves complex interactions involving intrinsic and extrinsic muscles, whose contractility is directed by the alignment of mesoscale fiber tracts...
  43. ncbi request reprint Intraoperative diffusion-tensor MR imaging: shifting of white matter tracts during neurosurgical procedures--initial experience
    Christopher Nimsky
    Department of Neurosurgery, University Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Radiology 234:218-25. 2005
    ..To prospectively evaluate the location of white matter tracts with diffusion-tensor imaging (DTI) during neurosurgical procedures...
  44. ncbi request reprint Preoperative and intraoperative diffusion tensor imaging-based fiber tracking in glioma surgery
    Christopher Nimsky
    Department of Neurosurgery, University Erlangen Nurnberg, Erlangen, Germany
    Neurosurgery 56:130-7; discussion 138. 2005
    ..To investigate the intraoperative displacement of major white matter tracts during glioma resection by comparing preoperative and intraoperative diffusion tensor imaging-based fiber tracking...
  45. ncbi request reprint A pilot study of normobaric oxygen therapy in acute ischemic stroke
    Aneesh B Singhal
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Stroke 36:797-802. 2005
    ..Therapies that transiently prevent ischemic neuronal death can potentially extend therapeutic time windows for stroke thrombolysis. We conducted a pilot study to investigate the effects of high-flow oxygen in acute ischemic stroke...
  46. ncbi request reprint Three-dimensional myoarchitecture of the bovine tongue demonstrated by diffusion spectrum magnetic resonance imaging with tractography
    Richard J Gilbert
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA
    Anat Rec A Discov Mol Cell Evol Biol 288:1173-82. 2006
    ..We postulate that the properties associated with these myofiber tracts predict the mechanical behavior of the tissue and thus constitute a method to relate structure and function for anatomically complex muscular tissues...
  47. ncbi request reprint Three dimensional myoarchitecture of the human tongue determined in vivo by diffusion tensor imaging with tractography
    Terry A Gaige
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Magn Reson Imaging 26:654-61. 2007
    ..To study the anatomical relationships involving the intrinsic and extrinsic myofiber populations of the human tongue employing diffusion tensor imaging (DTI) with tractography...
  48. ncbi request reprint Magnetic resonance spectroscopy study of oxygen therapy in ischemic stroke
    Aneesh B Singhal
    Stroke 38:2851-4. 2007
    ..Recent studies suggest that normobaric oxygen therapy (NBO) is neuroprotective in acute ischemic stroke...
  49. doi request reprint Resolving the three-dimensional myoarchitecture of bovine esophageal wall with diffusion spectrum imaging and tractography
    Richard J Gilbert
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Cell Tissue Res 332:461-8. 2008
    ....
  50. ncbi request reprint Do highly concentrated gadolinium chelates improve MR brain perfusion imaging? Intraindividually controlled randomized crossover concentration comparison study of 0.5 versus 1.0 mol/L gadobutrol
    Bernd Tombach
    Dept of Clinical Radiology, Univ of Münster, Albert Schweitzer Strasse 33, D 48129 Munster, Germany
    Radiology 226:880-8. 2003
    ..To assess the potential advantages of using a 1.0 mol/L versus 0.5 mol/L gadobutrol formulation for magnetic resonance (MR) brain perfusion imaging...