Research Topics
| Till BarnighausenSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Interventions to increase antiretroviral adherence in sub-Saharan Africa: a systematic review of evaluation studiesTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
Lancet Infect Dis 11:942-51. 2011..Future work should assess intervention targeting and selection of interventions based on behavioural theories relevant to sub-Saharan Africa...
HIV treatment as prevention: issues in economic evaluationTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts, United States of America
PLoS Med 9:e1001263. 2012..Third, the preventive effects of TasP are likely to alter the composition of the HIV-infected population over time, changing its biological and behavioral characteristics and leading to different costs and outcomes for ART...
Assessing the population health impact of market interventions to improve access to antiretroviral treatmentTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, Boston, MA 02115, USA
Health Policy Plan 27:467-76. 2012..We offer seven recommendations for ex ante and ex post assessment of population health impact of market interventions...
Health systems and HIV treatment in sub-Saharan Africa: matching intervention and programme evaluation strategiesTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts, USA
Sex Transm Infect 88:e2. 2012..The authors analyse likely effects of the latter shift on the feasibility of impact evaluation...
Rethinking the benefits and costs of childhood vaccination: the example of the Haemophilus influenzae type b vaccineTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, USA
Vaccine 29:2371-80. 2011..Future economic evaluations of childhood vaccinations should take full account of benefits and costs, so that policymakers have sufficient information to make well-informed decisions on vaccination implementation...
Designing financial-incentive programmes for return of medical service in underserved areas: seven management functionsTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
Hum Resour Health 7:52. 2009..Financial incentives, non-financial incentives, and compulsory service are not mutually exclusive and may positively affect each other's performance...
Financial incentives for return of service in underserved areas: a systematic reviewTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
BMC Health Serv Res 9:86. 2009..Financial incentives for return of service are intended to alleviate health worker shortages: A (future) health worker enters into a contract to work for a number of years in an underserved area in exchange for a financial pay-off...
Willingness to pay for social health insurance among informal sector workers in Wuhan, China: a contingent valuation studyTill Barnighausen
Africa Centre for Health and Population Studies, Mtubatuba, University of KwaZulu Natal, South Africa
BMC Health Serv Res 7:114. 2007....
"Conditional scholarships" for HIV/AIDS health workers: educating and retaining the workforce to provide antiretroviral treatment in sub-Saharan AfricaTill Barnighausen
University of KwaZulu Natal, Africa Centre for Health and Population Studies, P O Box 198, Mtubatuba, KwaZulu Natal 3935, South Africa
Soc Sci Med 68:544-51. 2009..Policy makers should consider implementing "conditional scholarships" for HAHW, especially in countries where health worker education capacity is currently underutilized or can be rapidly expanded...
Effect of concurrent sexual partnerships on rate of new HIV infections in a high-prevalence, rural South African population: a cohort studyFrank Tanser
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
Lancet 378:247-55. 2011..However, the effect of concurrent partnerships on HIV incidence has not been appropriately tested in a sub-Saharan African setting...
Adult mortality and antiretroviral treatment roll-out in rural KwaZulu-Natal, South AfricaAbraham J Herbst
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
Bull World Health Organ 87:754-62. 2009..To investigate trends in adult mortality in a population serviced by a public-sector antiretroviral therapy (ART) programme in rural South Africa using a demographic surveillance system...
Lack of a decline in HIV incidence in a rural community with high HIV prevalence in South Africa, 2003-2007Till Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
AIDS Res Hum Retroviruses 25:405-9. 2009..It is unlikely that the HIV epidemic in rural South Africa can be reversed without new or intensified efforts to prevent HIV infection...
Social exposure to an antiretroviral treatment programme in rural KwaZulu-NatalJacob Bor
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
Trop Med Int Health 16:988-94. 2011..To investigate the prevalence of social exposure to a large, government-run ART programme in rural South Africa...
Increases in adult life expectancy in rural South Africa: valuing the scale-up of HIV treatmentJacob Bor
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Post Office Box 198, Mtubatuba, KwaZulu Natal 3935, South Africa
Science 339:961-5. 2013..These gains in adult life expectancy signify the social value of ART and have implications for the investment decisions of individuals, governments, and donors...
Adjusting HIV prevalence for survey non-response using mortality rates: an application of the method using surveillance data from Rural South AfricaMakandwe Nyirenda
Africa Centre for Health and Population Studies, University of KwaZulu Natal, KwaZulu Natal, South Africa
PLoS ONE 5:e12370. 2010..The study objective was to evaluate whether population HIV prevalence estimates can be adjusted for survey non-response using mortality rates...
High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South AfricaFrank Tanser
Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
Science 339:966-71. 2013....
The socioeconomic determinants of HIV incidence: evidence from a longitudinal, population-based study in rural South AfricaTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
AIDS 21:S29-38. 2007..Both problems are avoided in longitudinal cohort studies...
Localized spatial clustering of HIV infections in a widely disseminated rural South African epidemicFrank Tanser
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
Int J Epidemiol 38:1008-16. 2009..We apply two spatial analytical techniques to investigate the micro-geographical patterns and clustering of HIV infections in a high prevalence, rural population in KwaZulu-Natal, South Africa...
Short communication: Prioritizing communities for HIV prevention in sub-Saharan AfricaTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts, USA
AIDS Res Hum Retroviruses 26:401-5. 2010..The three ranking schemes--by prevalence, incidence, and transmission probability--lead to significantly different community rank orders. Disease stage information should be collected in HIV surveys...
HIV incidence in rural South Africa: comparison of estimates from longitudinal surveillance and cross-sectional cBED assay testingTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Durban, South Africa
PLoS ONE 3:e3640. 2008....
Scale-up of a decentralized HIV treatment programme in rural KwaZulu-Natal, South Africa: does rapid expansion affect patient outcomes?Portia C Mutevedzi
Africa Centre for Health and Population Studies, Mtubatuba, South Africa
Bull World Health Organ 88:593-600. 2010....
Human resources for treating HIV/AIDS: needs, capacities, and gapsTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
AIDS Patient Care STDS 21:799-812. 2007....
National HIV prevalence estimates for sub-Saharan Africa: controlling selection bias with Heckman-type selection modelsDaniel R Hogan
Harvard School of Public Health, Department of Global Health and Population, 665 Huntington Ave, Building 1, Boston, MA 02115, USA
Sex Transm Infect 88:i17-23. 2012..We control for selection bias in national HIV prevalence estimates using a novel approach, which unlike conventional imputation can account for selection on unobserved factors...
In a study of a population cohort in South Africa, HIV patients on antiretrovirals had nearly full recovery of employmentJacob Bor
Harvard School of Public Health, Boston, MA, USA
Health Aff (Millwood) 31:1459-69. 2012..There are large economic benefits to HIV treatment. For some patients, further gains could be obtained from initiating antiretroviral therapy earlier, prior to HIV-related job loss...
Interventions to improve the performance of HIV health systems for treatment-as-prevention in sub-Saharan Africa: the experimental evidenceTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, KwaZulu Natal, South Africa
Curr Opin HIV AIDS 7:140-50. 2012..We review the experimental evidence on interventions to increase these rates...
HIV incidence estimation using the BED capture enzyme immunoassay: systematic review and sensitivity analysisTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, Boston, MA, USA
Epidemiology 21:685-97. 2010..Tests for recent HIV infection allow incidence estimation based on a single cross-sectional survey. The BED IgG-Capture Enzyme Immunoassay (BED assay) is a commercially available and widely used test for recent HIV infection...
Levels of childhood vaccination coverage and the impact of maternal HIV status on child vaccination status in rural KwaZulu-Natal, South Africa*James Ndirangu
Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
Trop Med Int Health 14:1383-93. 2009..To analyse coverage of childhood vaccinations in a rural South African population and investigate whether maternal HIV status is associated with children's vaccination status...
High HIV incidence in a community with high HIV prevalence in rural South Africa: findings from a prospective population-based studyTill Barnighausen
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
AIDS 22:139-44. 2008..To measure HIV incidence in a rural area of South Africa with high HIV prevalence and to analyze risk factors for acquisition of HIV using a prospective population-based cohort study...
Hypertension and obesity in adults living in a high HIV prevalence rural area in South AfricaAbraham Malaza
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Somkhele, KwaZulu Natal, South Africa
PLoS ONE 7:e47761. 2012..53 95% CI 1.14-2.06). Our study suggests that, cardiovascular risk factors of hypertension and obesity differ substantially between women and men in rural South Africa...
Do self-assessments of health predict future mortality in rural South Africa? The case of KwaZulu-Natal in the era of antiretroviral treatmentAnalia Olgiati
Harvard Center for Population and Development Studies, Cambridge, MA 02138, USA
Trop Med Int Health 17:844-53. 2012....
Validating five questions of antiretroviral nonadherence in a public-sector treatment program in rural South AfricaKrisda Chaiyachati
Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts, USA
AIDS Patient Care STDS 25:163-70. 2011..Available estimates of ART adherence in SSA are mostly based on studies using adherence questions. It is thus unlikely that our understanding of ART adherence in the region is correct...
Validating child vaccination status in a demographic surveillance system using data from a clinical cohort study: evidence from rural South AfricaJames Ndirangu
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
BMC Public Health 11:372. 2011..Childhood vaccination coverage can be estimated from a range of sources. This study aims to validate vaccination data from a longitudinal population-based demographic surveillance system (DSS) against data from a clinical cohort study...
Age-gaps in sexual partnerships: seeing beyond 'sugar daddies'Miles Q Ott
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
AIDS 25:861-3. 2011..Given the age-sex distribution of HIV prevalence in this population, interventions to decrease age-gaps in spousal relationships may be effective in reducing HIV incidence...
The prevalence and clinical presentation of antenatal depression in rural South AfricaTamsen Jean Rochat
Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
J Affect Disord 135:362-73. 2011..Early identification and treatment of antenatal depression may improve pregnancy outcomes and could serve as an early indicator of postnatal depression. Culturally sensitive and accurate diagnostic tools are urgently needed...
Renal impairment in a rural African antiretroviral programmeCara Franey
Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
BMC Infect Dis 9:143. 2009..With the increasing availability of the potentially nephrotixic drug, tenofovir, such information is important for the planning of antiretroviral programmes..
Economics of antiretroviral treatment vs. circumcision for HIV preventionTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 109:21271-6. 2012..Given South Africa's current annual ART spending, the $5 billion in savings offered by MMC and ART over TasP in the next decade, for similar health benefits, challenges the widely hailed status of TasP as a game changer...
Health workers at the core of the health system: framework and research issuesSudhir Anand
University of Oxford, Department of Economics, Oxford, UK
Health Policy 105:185-91. 2012..vertically structured health systems...
The global pediatric antiretroviral market: analyses of product availability and utilization reveal challenges for development of pediatric formulations and HIV/AIDS treatment in childrenBrenda Waning
Department of Family Medicine, Boston University School of Medicine, One Boston Medical Center Place, Dowling 5 South, Boston, MA 02118, USA
BMC Pediatr 10:74. 2010..Research on uptake and dispersion of these improved products across countries and international organizations has not been conducted but is needed to inform next steps towards improving child health...
Intervening in global markets to improve access to HIV/AIDS treatment: an analysis of international policies and the dynamics of global antiretroviral medicines marketsBrenda Waning
Department of Family Medicine, Boston University School of Medicine, One Boston Medical Center Place, Dowling 5 South, Boston, MA 02118, USA
Global Health 6:9. 2010..Global initiatives aim to promote efficient global ARV markets, yet little is known about market dynamics and the impact of global policy interventions...
Precommitting to serve the underservedNir Eyal
Harvard Medical School Division of Medical Ethics, The Harvard University Program in Ethics and Health, 641 Huntington Avenue, Boston, MA 02115, USA
Am J Bioeth 12:23-34. 2012..Policymakers should consider introducing conditional scholarships, including long-term versions, as a means to increasing the supply of physicians to medically underserved areas...
Correcting HIV prevalence estimates for survey nonparticipation using Heckman-type selection modelsTill Barnighausen
Department of Global Health and Population, Harvard School of Public Health, Boston, MA, USA
Epidemiology 22:27-35. 2011..quot; These approaches lead to biased estimates, if unobserved factors are associated with both survey participation and HIV status...
Human resources needs for universal access to antiretroviral therapy in South Africa: a time and motion studyJan Ac Hontelez
Africa Centre for Health and Population Studies, University of KwaZulu Natal, Mtubatuba, South Africa
Hum Resour Health 10:39. 2012..abstract:..
A new general biomarker-based incidence estimatorReshma Kassanjee
DST NRF Centre of Excellence in Epidemiological Modelling and Analysis SACEMA, University of Stellenbosch, Stellenbosch, South Africa
Epidemiology 23:721-8. 2012..Despite widespread applications to HIV, there is currently no consensus on the correct handling of biomarker results classifying persons as "recently" infected long after the infections occurred...
High uptake of HIV testing for tuberculosis patients in an integrated primary health care HIV/TB programme in rural KwaZulu-NatalClaudia Wallrauch
Africa Centre for Health and Population Studies, University of KwaZulu Natal
S Afr Med J 100:146-7. 2010..We describe our efforts to ensure high HIV testing rates in TB patients via an integrated programme at primary health care level in rural KwaZulu-Natal...
Study-design selection criteria in systematic reviews of effectiveness of health systems interventions and reforms: A meta-reviewPeter C Rockers
Department of Global Health and Population, Harvard School of Public Health, Boston, MA 02115, USA
Health Policy 104:206-14. 2012..We discuss the advantages and disadvantages of the current practices regarding study-design selection in systematic reviews of health systems research as well as alternative approaches...
Mortality levels and trends by HIV serostatus in rural South AfricaMakandwe Nyirenda
Africa Centre for Health and Population Studies, University of KwaZulu Natal, South Africa
AIDS 21:S73-9. 2007..To examine mortality differentials in HIV-infected and uninfected adults by demographic characteristics and the effect of non-testing on the level and pattern of age-sex specific mortality...
Population and antenatal-based HIV prevalence estimates in a high contracepting female population in rural South AfricaBrian D Rice
Africa Centre for Health and Population Studies, KwaZulu Natal, South Africa
BMC Public Health 7:160. 2007..There is particular emphasis on unrepresentative selection of ANC clinics and unrepresentative testing in the population...
Cohort Profile: Africa Centre Demographic Information System (ACDIS) and population-based HIV surveyFrank Tanser
Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Mtubatuba, South Africa
Int J Epidemiol 37:956-62. 2008
Male circumcision to cut HIV risk in the general populationMarie-Louise Newell
Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, KwaZulu-Natal 3935, South Africa
Lancet 369:617-9. 2007
