Research Topics
| Jamil AzziSummaryAffiliation: Harvard University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Immunological aspects of pancreatic islet cell transplantationJamil Azzi
Transplantation Research Center TRC, Brigham and Women s Hospital, Harvard Medical School, 227 Longwood Avenue, Boston, MA 02115, USA
Expert Rev Clin Immunol 6:111-24. 2010..We will also briefly discuss the immunosuppressive regimens used and the recent radiologic techniques in the detection of engraftment and early rejection of islet cells...
The novel role of SERPINB9 in cytotoxic protection of human mesenchymal stem cellsNajib El Haddad
Transplantation Research Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Immunol 187:2252-60. 2011..These findings contribute to the development of MSC-based therapies for diseases...
Mesenchymal stem cells express serine protease inhibitor to evade the host immune responseNajib El Haddad
Transplantation Research Center, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
Blood 117:1176-83. 2011..Our data could serve as a basis for future SPI-based strategies to regulate the survival and function of MSCs after administration and to enhance the efficacy of MSC-based therapy for diseases...
The novel therapeutic effect of phosphoinositide 3-kinase-γ inhibitor AS605240 in autoimmune diabetesJamil Azzi
Transplantation Research Center, Renal Division, Brigham and Women s Hospital and Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
Diabetes 61:1509-18. 2012..These studies demonstrate the key role of the PI3Kγ pathway in determining the balance of Tregs and autoreactive cells regulating autoimmune diabetes...
Clinical transplantation tolerance: a myth no more, butJamil Azzi
Transplantation Research Center, Renal Division, Brigham and Women s Hospital and Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Am J Kidney Dis 54:1005-11. 2009....
Polylactide-cyclosporin A nanoparticles for targeted immunosuppressionJamil Azzi
Transplant Research Center, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115, USA
FASEB J 24:3927-38. 2010..This innovative nanoparticulate CsA delivery technology constitutes a strong basis for future targeted delivery of immunosuppressive drugs with improved efficiency and reduced toxicity...
Impairment of immune systems in diabetesChristopher Ting
Transplantation Research Center Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Adv Exp Med Biol 771:62-75. 2012..Like any complex disease, the variation in severity and incidence of T1DM can be attributed to a combination of genetic and environmental factors...
Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetesMollie Jurewicz
Transplantation Research Center, Children s Hospital and Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes 59:3139-47. 2010..Here, we examine this question by testing the ability of congenic MSCs, obtained from the NOR mouse strain, to reverse recent-onset type 1 diabetes in NOD mice, as well as determine the immunomodulatory effects of NOR MSCs in vivo...
