S E Artandi

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint A critical role for telomeres in suppressing and facilitating carcinogenesis
    S E Artandi
    Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Curr Opin Genet Dev 10:39-46. 2000
  2. ncbi request reprint Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    S E Artandi
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Nature 406:641-5. 2000
  3. ncbi request reprint Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation
    K K Wong
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Nat Genet 26:85-8. 2000
  4. ncbi request reprint p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    L Chin
    Department of Adult Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cell 97:527-38. 1999

Collaborators

Detail Information

Publications4

  1. ncbi request reprint A critical role for telomeres in suppressing and facilitating carcinogenesis
    S E Artandi
    Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Curr Opin Genet Dev 10:39-46. 2000
    ..Recent data suggest that the severe chromosomal instability of telomere crisis promotes secondary genetic changes that facilitate carcinogenesis. Reactivation of telomerase stabilizes telomere ends and allows continued tumor growth...
  2. ncbi request reprint Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    S E Artandi
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Nature 406:641-5. 2000
    ..Our data suggest a model in which telomere dysfunction brought about by continual epithelial renewal during life generates the massive ploidy changes associated with the development of epithelial cancers...
  3. ncbi request reprint Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation
    K K Wong
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Nat Genet 26:85-8. 2000
    ..Our findings establish a intimate relationship between functionally intact telomeres and the genomic, cellular and organismal response to ionizing radiation...
  4. ncbi request reprint p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    L Chin
    Department of Adult Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cell 97:527-38. 1999
    ....