Research Topics
Genomes and Genes
| J P ArmSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptorJ P Arm
Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
J Immunol 159:2342-9. 1997..The data suggest that HM18 is a novel mononuclear cell inhibitory receptor homologous to mouse gp49B1...
Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49M C Castells
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115
J Biol Chem 269:8393-401. 1994..Thus, cloning of the gp49B gene has established the organization of one of the gp49 genes and provided evidence of alternate splicing of transcripts from that gene...
Interleukin-3 regulates development of the 5-lipoxygenase/leukotriene C4 synthase pathway in mouse mast cellsM Murakami
Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Biol Chem 270:22653-6. 1995....
Low molecular weight group IIA and group V phospholipase A(2) enzymes have different intracellular locations in mouse bone marrow-derived mast cellsC O Bingham
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
J Biol Chem 274:31476-84. 1999..The spatial segregation of group IIA PLA(2) and group V PLA(2) implies that these enzymes are not functionally redundant...
Molecular cloning of the gene for human leukotriene C4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35J F Penrose
Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
J Biol Chem 271:11356-61. 1996....
Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cellsH Fujishima
Department of Medicine, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 96:4803-7. 1999....
A heparin-sensitive phospholipase A2 and prostaglandin endoperoxide synthase-2 are functionally linked in the delayed phase of prostaglandin D2 generation in mouse bone marrow-derived mast cellsC O Bingham
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
J Biol Chem 271:25936-44. 1996..Furthermore, this heparin-sensitive PLA2 likely represents a novel PLA2 or a new function for a known low molecular weight PLA2...
Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cellsM Murakami
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115
J Biol Chem 269:22269-75. 1994..Thus, at a time when both PGHS-1 and PGHS-2 are present in bone marrow-derived mast cells, they function independently by coupling to different stimulus-initiated pathways to PGD2 generation from endogenously derived arachidonic acid...
Intracellular degradation of Fc gamma RIII in mouse bone marrow culture-derived progenitor mast cells prevents its surface expression and associated functionR B Lobell
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115
J Biol Chem 268:1207-12. 1993....
Molecular cloning of gp49, a cell-surface antigen that is preferentially expressed by mouse mast cell progenitors and is a new member of the immunoglobulin superfamilyJ P Arm
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115
J Biol Chem 266:15966-73. 1991..Thus, gp49, a membrane glycoprotein preferentially expressed by the progenitor mast cell population, is a new member of the immunoglobulin superfamily...
Genomic organization of the human leukocyte immunoglobulin-like receptors within the leukocyte receptor complex on chromosome 19q13.4W R Liu
Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
Immunogenetics 51:659-69. 2000..4 that is immediately centromeric of the killer cell Ig-like receptor genes and are separated from one another by approximately 20 to 30 kb, suggesting that they arose by gene duplication from a common ancestor...
A novel group of phospholipase A2s preferentially expressed in type 2 helper T cellsI C Ho
Department of Immunology and Infectious Diseases, Harvard School of Public Health, Division of Rheumatology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Biol Chem 276:18321-6. 2001..These results suggest that group XII and group V PLA(2)s might participate in helper T cell immune response through release of immediate second signals and generation of downstream eicosanoids...
c-kit ligand mediates increased expression of cytosolic phospholipase A2, prostaglandin endoperoxide synthase-1, and hematopoietic prostaglandin D2 synthase and increased IgE-dependent prostaglandin D2 generation in immature mouse mast cellsM Murakami
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115
J Biol Chem 270:3239-46. 1995....
Down-regulation of leucocyte immunoglobulin-like receptor expression in the synovium of rheumatoid arthritis patients after treatment with disease-modifying anti-rheumatic drugsO A Huynh
Inflammatory Diseases Research Unit, Wallace Wurth Building, University of New South Wales, Sydney 2052, Australia
Rheumatology (Oxford) 46:742-51. 2007....
