Veronica A AlvarezSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Frequency-dependent synchrony in locus ceruleus: role of electrotonic couplingVeronica A Alvarez
Vollum Institute, Oregon Health and Science University, Portland, OR 97201, USA
Proc Natl Acad Sci U S A 99:4032-6. 2002..In slices from adult animals, the combination of electrotonic coupling and firing frequency are the key elements that regulate synchronous firing in this nucleus...
Anatomical and physiological plasticity of dendritic spinesVeronica A Alvarez
Harvard Medical School, Department of Neurobiology, Boston, Massachusetts 02115, USA
Annu Rev Neurosci 30:79-97. 2007..Nevertheless, morphological changes are not required for all forms of synaptic plasticity, and whether changes in the spine shape and size significantly impact synaptic signals is unclear...
mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalizationVeronica A Alvarez
Vollum Institute and Department of Physiology and Pharmacology, Oregon Health and Sciences University, Portland, Oregon 97201, USA
J Neurosci 22:5769-76. 2002..Identification and characterization of the biophysical properties of agonists that favor desensitization and internalization of receptors will lead to a better understanding of opioid signaling...
Distinct structural and ionotropic roles of NMDA receptors in controlling spine and synapse stabilityVeronica A Alvarez
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Neurosci 27:7365-76. 2007..Thus, although ionotropic properties of NMDARs induce synaptic plasticity, it is the physical interactions of the C-tail of the receptor that mediate the long-term stabilization of synapses and spines...
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2Sohail F Tavazoie
Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, Massachusetts 02115, USA
Nat Neurosci 8:1727-34. 2005..Thus, the TSC pathway regulates growth and synapse function in neurons, and perturbations of neuronal structure and function are likely to contribute to the pathogenesis of the neurological symptoms of TSC...
Retraction of synapses and dendritic spines induced by off-target effects of RNA interferenceVeronica A Alvarez
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Neurosci 26:7820-5. 2006..Our results indicate that off-target effects of RNAi severely perturb neuronal structure and function and may lead to the functional withdrawal of affected cells from the brain circuitry...
