Katrine Almind

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi [Genetic defects in insulin signalling proteins. Implications for the pathogenesis of type 2 diabetes]
    Katrine Almind
    Research Division, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Ugeskr Laeger 164:1021-6. 2002
  2. ncbi Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance
    Katrine Almind
    Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA
    Diabetes 52:1535-43. 2003
  3. ncbi Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice
    Rohit N Kulkarni
    Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA
    Diabetes 52:1528-34. 2003
  4. ncbi Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice
    Katrine Almind
    Research Division, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 53:3274-85. 2004
  5. ncbi Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome
    Sudha B Biddinger
    Research Division, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA
    Diabetes 54:1314-23. 2005
  6. ncbi Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
    Katrine Almind
    Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 104:2366-71. 2007
  7. ncbi A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease
    Marcelo A Mori
    Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 59:2960-71. 2010
  8. ncbi Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha
    Katrine Almind
    Research Division, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 99:2124-8. 2002
  9. ncbi Mitochondrial proton leak in obesity-resistant and obesity-prone mice
    Brian D Fink
    University of Iowa, Iowa City Veterans Affairs Medical Center, Iowa City, IA 52242, USA
    Am J Physiol Regul Integr Comp Physiol 293:R1773-80. 2007

Collaborators

Detail Information

Publications9

  1. ncbi [Genetic defects in insulin signalling proteins. Implications for the pathogenesis of type 2 diabetes]
    Katrine Almind
    Research Division, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Ugeskr Laeger 164:1021-6. 2002
    ....
  2. ncbi Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance
    Katrine Almind
    Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA
    Diabetes 52:1535-43. 2003
    ....
  3. ncbi Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice
    Rohit N Kulkarni
    Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA
    Diabetes 52:1528-34. 2003
    ....
  4. ncbi Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice
    Katrine Almind
    Research Division, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 53:3274-85. 2004
    ..e., the "thrifty gene," is a dominant-acting genetic determinant of diet-induced obesity in mice and can be linked to a locus on chromosome 14, including genes linked to adipose development and insulin sensitivity...
  5. ncbi Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome
    Sudha B Biddinger
    Research Division, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA
    Diabetes 54:1314-23. 2005
    ..Thus, dietary fat and genetic background act through SREBP-1c and SCD1 to affect hepatic lipid metabolism contributing to the development of the metabolic syndrome...
  6. ncbi Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
    Katrine Almind
    Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 104:2366-71. 2007
    ..Thus, ectopic deposits of brown adipose tissue in intermuscular depots with regulatable expression of UCP1 provide a genetically based mechanism of protection from weight gain and metabolic syndrome between strains of mice...
  7. ncbi A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease
    Marcelo A Mori
    Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 59:2960-71. 2010
    ..Our goal was to identify early molecular signatures predicting genetic risk to these metabolic diseases using two strains of mice that differ greatly in disease susceptibility...
  8. ncbi Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha
    Katrine Almind
    Research Division, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 99:2124-8. 2002
    ..Thus, the Met-326Ile variant of p85alpha is functional for intracellular signaling and adipocyte differentiation but has small alterations in protein expression and activity that could play a role in modifying insulin action...
  9. ncbi Mitochondrial proton leak in obesity-resistant and obesity-prone mice
    Brian D Fink
    University of Iowa, Iowa City Veterans Affairs Medical Center, Iowa City, IA 52242, USA
    Am J Physiol Regul Integr Comp Physiol 293:R1773-80. 2007
    ..But, this is only achieved only at a higher body mass and, therefore, may be adaptive rather than preventative. Neither obesity-prone nor resistant mice respond to HF feeding by expressing more UCP1 in ectopic BAT within muscle tissue...