M P Alexander

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Cognitive impairments due to focal cerebellar injuries in adults
    Michael P Alexander
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Cortex 48:980-90. 2012
  2. doi request reprint Cognitive and functional outcome after out of hospital cardiac arrest
    Michael P Alexander
    Cognitive Neurology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Int Neuropsychol Soc 17:364-8. 2011
  3. ncbi request reprint Impaired concentration due to frontal lobe damage from two distinct lesion sites
    M P Alexander
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neurology 65:572-9. 2005
  4. ncbi request reprint Regional frontal injuries cause distinct impairments in cognitive control
    M P Alexander
    Behavioral Neurology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA, USA
    Neurology 68:1515-23. 2007
  5. ncbi request reprint Impairments of procedures for implementing complex language are due to disruption of frontal attention processes
    Michael P Alexander
    Harvard Medical School, Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    J Int Neuropsychol Soc 12:236-47. 2006
  6. ncbi request reprint Age-related differences in movement representation
    S Hutchinson
    Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Neuroimage 17:1720-8. 2002
  7. ncbi request reprint The neurological and cognitive sequelae of cardiac arrest
    C Lim
    Behavioral Neurology Unit KS 2, Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neurology 63:1774-8. 2004
  8. ncbi request reprint California Verbal Learning Test: performance by patients with focal frontal and non-frontal lesions
    M P Alexander
    Rotman Research Institute of Baycrest Centre for Geriatric Care, University of Toronto, Toronto, ON, Canada
    Brain 126:1493-503. 2003
  9. ncbi request reprint Central neurogenic hyperventilation: a case report and discussion of pathophysiology
    Andrew W Tarulli
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Arch Neurol 62:1632-4. 2005
  10. doi request reprint Stroke and episodic memory disorders
    Chun Lim
    The Cognitive Neurology Unit, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neuropsychologia 47:3045-58. 2009

Research Grants

  1. Cognition and Functional Recovery after Cardiac Arrest
    Michael Alexander; Fiscal Year: 2007

Detail Information

Publications31

  1. doi request reprint Cognitive impairments due to focal cerebellar injuries in adults
    Michael P Alexander
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Cortex 48:980-90. 2012
    ..This investigation was designed to assess whether focal cerebellar injuries in adults would cause impairment on tasks previously demonstrated to be sensitive to prefrontal lesions...
  2. doi request reprint Cognitive and functional outcome after out of hospital cardiac arrest
    Michael P Alexander
    Cognitive Neurology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Int Neuropsychol Soc 17:364-8. 2011
    ..Coma duration was associated with group. Neither group had a high prevalence of depression. For most patients within the "middle range" of acute severity of OHCA, cognitive and functional outcomes at 3 months were encouraging...
  3. ncbi request reprint Impaired concentration due to frontal lobe damage from two distinct lesion sites
    M P Alexander
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neurology 65:572-9. 2005
    ..Some form of impairment in attention is often asserted to cause the revealed deficits...
  4. ncbi request reprint Regional frontal injuries cause distinct impairments in cognitive control
    M P Alexander
    Behavioral Neurology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA, USA
    Neurology 68:1515-23. 2007
    ..Lesions of the frontal lobes may impair the capacity of patients to control otherwise intact cognitive operations in the face of ambiguous sensory input or conflicting possible responses...
  5. ncbi request reprint Impairments of procedures for implementing complex language are due to disruption of frontal attention processes
    Michael P Alexander
    Harvard Medical School, Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    J Int Neuropsychol Soc 12:236-47. 2006
    ....
  6. ncbi request reprint Age-related differences in movement representation
    S Hutchinson
    Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Neuroimage 17:1720-8. 2002
    ..This study has important implications for functional imaging experiments of neurological disorders in older subjects...
  7. ncbi request reprint The neurological and cognitive sequelae of cardiac arrest
    C Lim
    Behavioral Neurology Unit KS 2, Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neurology 63:1774-8. 2004
    ..Although cardiac arrest (CA) is commonly cited as a cause of amnesia, patients referred to the authors' center with a diagnosis of "amnesia" after CA rarely have isolated memory deficits...
  8. ncbi request reprint California Verbal Learning Test: performance by patients with focal frontal and non-frontal lesions
    M P Alexander
    Rotman Research Institute of Baycrest Centre for Geriatric Care, University of Toronto, Toronto, ON, Canada
    Brain 126:1493-503. 2003
    ..This study has demonstrated even finer differentiations within the frontal region than previously known...
  9. ncbi request reprint Central neurogenic hyperventilation: a case report and discussion of pathophysiology
    Andrew W Tarulli
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Arch Neurol 62:1632-4. 2005
    ..Central neurogenic hyperventilation is a rare condition with poorly understood pathophysiology...
  10. doi request reprint Stroke and episodic memory disorders
    Chun Lim
    The Cognitive Neurology Unit, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neuropsychologia 47:3045-58. 2009
    ....
  11. ncbi request reprint Chronic akinetic mutism after mesencephalic-diencephalic infarction: remediated with dopaminergic medications
    M P Alexander
    Memory Disorders Research Center, Boston University, Department of Neurology, Massachusetts, USA
    Neurorehabil Neural Repair 15:151-6. 2001
    ..The mechanism of abulia is more complex than simply a partial dopaminergic deficiency state and may persist even when AKM is treated and frontal cognitive functions are normal...
  12. ncbi request reprint Lesion site patterns in severe, nonverbal aphasia to predict outcome with a computer-assisted treatment program
    M A Naeser
    Department of Neurology, Boston University School of Medicine and the Harold Goodglass Aphasia Research Center at the Department of Veterans Affairs Medical Center, Mass, USA
    Arch Neurol 55:1438-48. 1998
    ....
  13. pmc Triangular backgrounds shift the bias of line bisection performance in hemispatial neglect
    M B Shulman
    Department of Neurology, New York University Medical Center, New York, USA
    J Neurol Neurosurg Psychiatry 72:68-72. 2002
    ..Patients with left neglect on line bisection show normal implicit sensitivity to manipulations of both the stimulus and the visual background. Three experiments were designed to define this sensitivity more exactly...
  14. ncbi request reprint Elevated false recognition in patients with frontal lobe damage is neither a general nor a unitary phenomenon
    Mieke Verfaellie
    Boston University School of Medicine, Memory Disorders Research Center, Boston Veterans Affairs Health Care System, Boston, MA, USA
    Neuropsychology 18:94-103. 2004
    ..These patients exhibited impaired monitoring and verification processes. The findings demonstrate that elevated false recognition is not characteristic of all frontal patients and may result from more than 1 underlying mechanism...
  15. doi request reprint Impaired list learning is not a general property of frontal lesions
    Michael P Alexander
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Cogn Neurosci 21:1422-34. 2009
    ..Small sample sizes, confounding anomia, and incomplete representation of all frontal regions have prevented consistent demonstration of distinct regional frontal effects on this task...
  16. ncbi request reprint The evidence for brain injury in whiplash injuries
    Michael P Alexander
    Harvard Medical School, Boston, Massachusetts, USA
    Pain Res Manag 8:19-23. 2003
  17. ncbi request reprint A role for right medial prefontal cortex in accurate feeling-of-knowing judgements: evidence from patients with lesions to frontal cortex
    David M Schnyer
    Memory Disorders Research Center, Boston VA Healthcare System and Boston University School of Medicine 151A, 150 South Huntington Avenue, Boston, MA 02130 4817, USA
    Neuropsychologia 42:957-66. 2004
    ..These findings provide functional and anatomical evidence for a dissociation between recall confidence and prospective memory monitoring and are discussed in terms of familiarity and access theories of FOK predictions...
  18. ncbi request reprint Dissociations within the anterior attentional system: effects of task complexity and irrelevant information on reaction time speed and accuracy
    Donald T Stuss
    The Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    Neuropsychology 16:500-13. 2002
    ..The frontal lobes, particularly right dorsolateral, were required to inhibit an incorrect response. There are at least 3 functionally and anatomically separable anterior attentional processes...
  19. ncbi request reprint Multiple frontal systems controlling response speed
    Donald T Stuss
    The Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Neuropsychologia 43:396-417. 2005
    ..Monitoring of stimulus occurrence and response behaviour in order to enhance the speed of response to upcoming stimuli is sensitive to RL lesions...
  20. ncbi request reprint Staying on the job: the frontal lobes control individual performance variability
    Donald T Stuss
    Rotman Research Institute, Baycrest Centre for Geriatric Care and University of Toronto, Ontario, Canada
    Brain 126:2363-80. 2003
    ..Damage to different frontal regions causes different profiles of abnormal variability. Fluctuations in performance of a task may underlie some of the reported difficulties in daily tasks reported by patients with frontal injuries...
  21. doi request reprint The multiple dimensions of sustained attention
    Tim Shallice
    SISSA, Trieste, Italy
    Cortex 44:794-805. 2008
    ..1995). The most plausible interpretation is in terms of energising processes which involve the SM frontal cortex and monitoring processes which involve the RL frontal cortex...
  22. ncbi request reprint Rehabilitation of executive functioning after focal damage to the cerebellum
    Tom A Schweizer
    Rotman Research Institute, Baycrest, Toronto, ON, Canada
    Neurorehabil Neural Repair 22:72-7. 2008
    ..This is the first report on the rehabilitation of impaired executive functioning following focal damage to the cerebellum and in the presence of intact frontal cortex...
  23. ncbi request reprint Fast and efficient visuotemporal attention requires the cerebellum
    Tom A Schweizer
    Rotman Research Institute, Baycrest, 3560 Bathurst Street, Toronto, Ont M6A 2E1, Canada
    Neuropsychologia 45:3068-74. 2007
    ..These data provide evidence implicating the cerebellum as a critical node in the neuroanatomical network underlying visuotemporal attention and provide further evidence for the role of the cerebellum in non-motor behaviors...
  24. pmc Is there a dysexecutive syndrome?
    Donald T Stuss
    Rotman Research Institute, Baycrest, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Philos Trans R Soc Lond B Biol Sci 362:901-15. 2007
    ..Although distinct, these processes are flexibly assembled in response to context, complexity and intention over real time into different networks within the frontal regions and between frontal and posterior regions...
  25. ncbi request reprint Keeping time: effects of focal frontal lesions
    Terence W Picton
    The Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ont, Canada M6A 2E1
    Neuropsychologia 44:1195-209. 2006
    ..In contrast, the superior medial regions of the frontal lobe are necessary to maintain consistent timing performance over prolonged periods of time...
  26. ncbi request reprint Effects of focal frontal lesions on response inhibition
    Terence W Picton
    Rotman Research Institute at Baycrest, Toronto, Ontario M6A 2E1, Canada
    Cereb Cortex 17:826-38. 2007
    ..Lesions to the right ventrolateral prefrontal cortex (Brodmann areas 44, 45, 47) also increased the variability of response, perhaps by disrupting monitoring performance...
  27. ncbi request reprint Cognitive rehabilitation in the elderly: a randomized trial to evaluate a new protocol
    Donald T Stuss
    Rotman Research Institute, Baycrest, Toronto, Ontario, Canada
    J Int Neuropsychol Soc 13:120-31. 2007
    ..The results for each functional domain are reported in separate papers in this series...
  28. ncbi request reprint Triangular backgrounds shift line bisection performance in hemispatial neglect: the critical point
    Michael Esterman
    Geriatric Neuropsychology Laboratory, Geriatric Research, Education and Clinical Center, VA Boston Healthcare System, Massachusetts 02130, USA
    J Int Neuropsychol Soc 8:721-6. 2002
    ..Similar geometric illusions that are also intact in neglect, along with these results, suggest that preattentive, implicit visual processing is preserved in neglect and drives these illusions...
  29. ncbi request reprint The cerebellum mediates conflict resolution
    Tom A Schweizer
    Rotman Research Institute, Baycrest, Toronto, Ontario, Canada
    J Cogn Neurosci 19:1974-82. 2007
    ..These results are the first demonstration of impaired conflict resolution following cerebellar lesions in the presence of an intact prefrontal cortex...
  30. ncbi request reprint Outpatient rehabilitation of patients with chronic cognitive impairments after ruptured anterior communicating artery aneurysms reduces the burden of care: a pilot study
    Virginia M Mills
    Community Rehab Care, Inc, Newton, MA 02458, USA
    Brain Inj 20:1183-8. 2006
    ..To describe the functional outcome of 19 patients with anterior communicating artery aneurysm following the completion of an inter-disciplinary out-patient rehabilitation programme...
  31. ncbi request reprint Recovery of ambulation after traumatic brain injury
    Douglas I Katz
    HealthSouth Braintree Rehabilitation Hospital, 250 Pond Street, Braintree, MA 02184, USA
    Arch Phys Med Rehabil 85:865-9. 2004
    ..To identify variables that are predictive of independent ambulation after traumatic brain injury (TBI) and to define the time course of recovery...

Research Grants3

  1. Cognition and Functional Recovery after Cardiac Arrest
    Michael Alexander; Fiscal Year: 2007
    ....