Marilyn S Albert
Affiliation: Harvard University
- Neuropsychological function in patients with chronic fatigue syndrome, multiple sclerosis, and depressionE Daly
Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA
Appl Neuropsychol 8:12-22. 2001..The findings support the view that the cognitive deficits found in CFS cannot be attributed solely to the presence of depressive symptomatology in the patients...
- Preclinical prediction of AD using neuropsychological testsM S Albert
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
J Int Neuropsychol Soc 7:631-9. 2001....
- Structural magnetic resonance imaging in established and prodromal Alzheimer disease: a reviewMonika Atiya
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston University, Boston, Massachusetts 02129, USA
Alzheimer Dis Assoc Disord 17:177-95. 2003
- Detection of very early Alzheimer disease through neuroimagingMarilyn S Albert
Department of Psychiatry, Harvard Medical School, Massachusetts Geneal Hospital, Charlestown, Massachusetts, USA
Alzheimer Dis Assoc Disord 17:S63-5. 2003
- Novel fearful faces activate the amygdala in healthy young and elderly adultsChristopher I Wright
Psychiatric Neuroimaging Research Program, Massachusetts General Hospital, 13th St, Bldg 149, CNY 2613, Charlestown, MA 02129, USA
Neurobiol Aging 27:361-74. 2006..However, there were significantly greater activations in the inferior temporal cortex in the young versus elderly subjects...
- The SIST-M: predictive validity of a brief structured clinical dementia rating interviewOlivia I Okereke
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Alzheimer Dis Assoc Disord 26:225-31. 2012....
- Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer diseaseMaija Pihlajamaki
Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, MA, USA
Alzheimer Dis Assoc Disord 24:28-36. 2010..Altered fMRI activity of the posteromedial areas of the brain default network may be an early indicator of risk for AD...
- An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interestRahul S Desikan
Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, W701, Boston, MA 02118, USA
Neuroimage 31:968-80. 2006....
- Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairmentBradford C Dickerson
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
Arch Gen Psychiatry 64:1443-50. 2007....
- Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy agingChristopher M Holland
Center for Neurological Imaging, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Stroke 39:1127-33. 2008..We sought to determine whether the spatial distribution of WMHs discriminates between different disease groups and healthy aging individuals and whether these distributions are related to local cerebral perfusion patterns...
- Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementiaEric E Smith
Neurology Clinical Trials Unit, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Arch Neurol 65:94-100. 2008..To determine whether magnetic resonance imaging (MRI) white matter hyperintensities (WMH), whole-brain atrophy, and cardiovascular risk factors predict the development of cognitive decline and dementia...
- The Structured Interview & Scoring Tool-Massachusetts Alzheimer's Disease Research Center (SIST-M): development, reliability, and cross-sectional validation of a brief structured clinical dementia rating interviewOlivia I Okereke
Department of Psychiatry, Gerontology Research Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Arch Neurol 68:343-50. 2011..The Clinical Dementia Rating (CDR) and CDR Sum-of-Boxes can be used to grade mild but clinically important cognitive symptoms of Alzheimer disease. However, sensitive clinical interview formats are lengthy...
- Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysisKim A Celone
Memory Disorders Unit, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Neurosci 26:10222-31. 2006..These data may also provide functional evidence of the interaction between neocortical and medial temporal lobe pathology in early AD...
- Medial temporal lobe function and structure in mild cognitive impairmentBradford C Dickerson
Department of Neurology, Gerontology Research Unit, Massachusetts General Hospital, MGH East 149 2691, 149 13th Street, Charlestown, MA 02129, USA
Ann Neurol 56:27-35. 2004..We hypothesize that increased activation in MTL regions reflects a compensatory response to accumulating AD pathology and may serve as a marker for impending clinical decline...
- Hippocampal and neocortical activation during repetitive encoding in older personsErin Rand-Giovannetti
Gerontology Research Unit, Department of Psychiatry, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, and Johns Hopkins University, Baltimore, MD 21205, USA
Neurobiol Aging 27:173-82. 2006..Our findings suggest that hippocampal function is preserved in normal aging and that repetition-based memory enhancing techniques may engage primarily neocortical attentional networks...
- Differential amygdala habituation to neutral faces in young and elderly adultsMichelle M Wedig
Psychiatric Neuroimaging Research Program, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, 2nd Floor, Charlestown, MA 02129, USA
Neurosci Lett 385:114-9. 2005..We conclude that, in healthy elderly adults, the amygdala retains its adaptive habituation response, but speculate that intrinsic changes in amygdala anatomy during aging may modulate its laterality...
- Quantitative SPECT leads to improved performance in discrimination tasks related to prodromal Alzheimer's diseaseGeorges El Fakhri
Department of Radiology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Nucl Med 45:2026-31. 2004....
- Measuring cerebral atrophy and white matter hyperintensity burden to predict the rate of cognitive decline in Alzheimer diseaseAdam M Brickman
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, 630 W 168th St, Campus Box 16, New York, NY 10032, USA
Arch Neurol 65:1202-8. 2008..To determine if baseline measurements of cerebral atrophy and severity of white matter hyperintensity (WMH) predict the rate of future cognitive decline in patients with Alzheimer disease (AD)...
- Mild cognitive impairment and dementiaMarilyn S Albert
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21212, USA
Annu Rev Clin Psychol 2:379-88. 2006....
- Exploring candidate gene associations with neuropsychological performanceMatthew B McQueen
Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, Colorado 80309 0447, USA
Am J Med Genet B Neuropsychiatr Genet 144:987-91. 2007....
- Association between mind-body and cardiovascular exercises and memory in older adultsAgnes S Chan
Department of Psychology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
J Am Geriatr Soc 53:1754-60. 2005..Older adults who engaged in both types of exercise were also included to examine the combined effects...
- MRI-guided SPECT perfusion measures and volumetric MRI in prodromal Alzheimer diseaseGeorges El Fakhri
Department of Radiology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Arch Neurol 60:1066-72. 2003....
- Dissociating confidence and accuracy: functional magnetic resonance imaging shows origins of the subjective memory experienceElizabeth F Chua
Center for Neurocognitive Studies, Department of Neurology, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115
J Cogn Neurosci 16:1131-42. 2004..These findings may also aid understanding of eyewitness misidentifications and memory distortions...
- Memory decline: the boundary between aging and age-related diseaseMarilyn S Albert
Ann Neurol 51:282-4. 2002
- Achieving and maintaining cognitive vitality with agingHoward M Fillit
Institute for the Study of Aging, Inc, New York, NY 10153, USA
Mayo Clin Proc 77:681-96. 2002..The data presented in this review should interest physicians who provide preventive care management to middle-aged and older individuals who seek to maintain cognitive vitality with aging...
- Structural modeling of dynamic changes in memory and brain structure using longitudinal data from the normative aging studyJohn J McArdle
Department of Psychology, PO Box 400400, University of Virginia, Charlottesville, VA 22906 4400, USA
J Gerontol B Psychol Sci Soc Sci 59:P294-304. 2004....
- Predicting cognitive impairment in high-functioning community-dwelling older persons: MacArthur Studies of Successful AgingJoshua Chodosh
Division of Geriatrics, UCLA School of Medicine, 10945 Le Conte Avenue, Los Angeles, CA 90095, USA
J Am Geriatr Soc 50:1051-60. 2002..To examine whether simple cognitive tests, when applied to cognitively intact older persons, are useful predictors of cognitive impairment 7 years later...
- The relation of patient dependence to home health aide use in Alzheimer's diseaseRachel K Scherer
Cognitive Neuroscience Division, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Gertrude H Sergievsky Center, Department of Neurology, Columbia University Medical Center, 630 West 168th St, P and S Box 16, New York, NY 10032, USA
J Gerontol A Biol Sci Med Sci 63:1005-9. 2008..The objective of this study was to examine whether the Dependence Scale can predict home health aide (HHA) use...
- Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulinAleister J Saunders
Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Hum Mol Genet 12:2765-76. 2003..However, the negative case - control studies suggest that any underlying pathogenic polymorphisms have a modest effect, and may operate primarily among individuals with a family history of AD...
- Changing the trajectory of cognitive decline?Marilyn S Albert
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, USA
N Engl J Med 357:502-3. 2007
- Results of a high-resolution genome screen of 437 Alzheimer's disease familiesDeborah Blacker
Massachusetts General Hospital, Charlestown, MA, USA
Hum Mol Genet 12:23-32. 2003..Although some of these will surely prove to be false positives, these linkage signals should provide a valuable framework for future studies aimed at identifying additional susceptibility genes for late-onset AD...