Jyrki Ahveninen

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Psychophysics and neuronal bases of sound localization in humans
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA Electronic address
    Hear Res 307:86-97. 2014
  2. pmc Dissociable influences of auditory object vs. spatial attention on visual system oscillatory activity
    Jyrki Ahveninen
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
    PLoS ONE 7:e38511. 2012
  3. pmc Task-modulated "what" and "where" pathways in human auditory cortex
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, CNY 149 13th Street, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 103:14608-13. 2006
  4. ncbi request reprint MRI-constrained spectral imaging of benzodiazepine modulation of spontaneous neuromagnetic activity in human cortex
    Jyrki Ahveninen
    Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, CNY149 13th Street, Charlestown, MA 02129, USA
    Neuroimage 35:577-82. 2007
  5. ncbi request reprint Inherited auditory-cortical dysfunction in twin pairs discordant for schizophrenia
    Jyrki Ahveninen
    Department of Radiology, Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Biol Psychiatry 60:612-20. 2006
  6. pmc Neuronal representations of distance in human auditory cortex
    Norbert Kopco
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 109:11019-24. 2012
  7. pmc Brain networks of novelty-driven involuntary and cued voluntary auditory attention shifting
    Samantha Huang
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
    PLoS ONE 7:e44062. 2012
  8. pmc Onset timing of cross-sensory activations and multisensory interactions in auditory and visual sensory cortices
    Tommi Raij
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Bldg 149, 13 St, Charlestown, MA, USA
    Eur J Neurosci 31:1772-82. 2010
  9. pmc Attention-driven auditory cortex short-term plasticity helps segregate relevant sounds from noise
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 108:4182-7. 2011
  10. pmc Human posterior auditory cortex gates novel sounds to consciousness
    Iiro P Jaaskelainen
    Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 101:6809-14. 2004

Detail Information

Publications38

  1. pmc Psychophysics and neuronal bases of sound localization in humans
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA Electronic address
    Hear Res 307:86-97. 2014
    ..This article is part of a Special Issue entitled <Human Auditory Neuroimaging>. ..
  2. pmc Dissociable influences of auditory object vs. spatial attention on visual system oscillatory activity
    Jyrki Ahveninen
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
    PLoS ONE 7:e38511. 2012
    ..sound location ("where"). The alpha modulations could be interpreted to reflect enhanced crossmodal inhibition of feature-specific visual pathways and adjacent audiovisual association areas during "what" vs. "where" auditory attention...
  3. pmc Task-modulated "what" and "where" pathways in human auditory cortex
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, CNY 149 13th Street, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 103:14608-13. 2006
    ..This finding suggests that selective-attention effects are feature-specific in the human nonprimary auditory cortex and that they arise from enhanced tuning of receptive fields of task-relevant neuronal populations...
  4. ncbi request reprint MRI-constrained spectral imaging of benzodiazepine modulation of spontaneous neuromagnetic activity in human cortex
    Jyrki Ahveninen
    Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, CNY149 13th Street, Charlestown, MA 02129, USA
    Neuroimage 35:577-82. 2007
    ..Anatomically constrained spectral imaging displays the cortical loci of drug effects on oscillatory brain activity, providing a novel tool for human pharmacological neuroimaging...
  5. ncbi request reprint Inherited auditory-cortical dysfunction in twin pairs discordant for schizophrenia
    Jyrki Ahveninen
    Department of Radiology, Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Biol Psychiatry 60:612-20. 2006
    ..We used magnetoencephalography (MEG) and electroencephalography (EEG) to investigate the inheritance of auditory-cortical deficiencies in twin pairs discordant for schizophrenia...
  6. pmc Neuronal representations of distance in human auditory cortex
    Norbert Kopco
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 109:11019-24. 2012
    ....
  7. pmc Brain networks of novelty-driven involuntary and cued voluntary auditory attention shifting
    Samantha Huang
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
    PLoS ONE 7:e44062. 2012
    ..Finally, novels and targets activated much wider areas of superior temporal auditory cortices than shifting cues...
  8. pmc Onset timing of cross-sensory activations and multisensory interactions in auditory and visual sensory cortices
    Tommi Raij
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Bldg 149, 13 St, Charlestown, MA, USA
    Eur J Neurosci 31:1772-82. 2010
    ..Audiovisual interactions started at 85 ms in the left auditory, 80 ms in the right auditory and 74 ms in the visual cortex, i.e., 3-21 ms after inputs from the two modalities converged...
  9. pmc Attention-driven auditory cortex short-term plasticity helps segregate relevant sounds from noise
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 108:4182-7. 2011
    ..In conclusion, a simple gain model alone cannot explain auditory selective attention. In nonprimary auditory cortices, attention-driven short-term plasticity retunes neurons to segregate relevant sounds from noise...
  10. pmc Human posterior auditory cortex gates novel sounds to consciousness
    Iiro P Jaaskelainen
    Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 101:6809-14. 2004
    ..Our converging findings suggest that transient adaptation of feature-specific neurons within human posterior auditory cortex filters superfluous sounds from entering one's awareness...
  11. pmc Parallel input makes the brain run faster
    Tommi Raij
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Neuroimage 40:1792-7. 2008
    ..This arrangement could also allow very early top-down modulation of the bottom-up stream of sensory information...
  12. pmc Multimodal functional imaging using fMRI-informed regional EEG/MEG source estimation
    Wanmei Ou
    Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA
    Neuroimage 52:97-108. 2010
    ..Analysis using human E/MEG-fMRI data reveals that FIRE significantly reduces the ambiguities in source localization present in the minimum-norm estimates, and that it accurately captures activation timing in adjacent functional regions...
  13. doi request reprint Evidence for distinct human auditory cortex regions for sound location versus identity processing
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, Massachusetts 02129, USA
    Nat Commun 4:2585. 2013
    ..This double dissociation provides direct causal support for parallel processing of sound identity features in anterior AC and sound location in posterior AC. ..
  14. doi request reprint Lateralized parietotemporal oscillatory phase synchronization during auditory selective attention
    Samantha Huang
    Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 86:461-9. 2014
    ..The ROI analysis revealed similarly lateralized differences also in the beta and lower theta bands. Taken together, our results support the view that the right parietal cortex dominates auditory spatial attention. ..
  15. pmc Whole-head rapid fMRI acquisition using echo-shifted magnetic resonance inverse imaging
    Wei Tang Chang
    Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan
    Neuroimage 78:325-38. 2013
    ..With the capabilities of being able to distinguish the timing differences in the millisecond scale, echo-shifted InI could be a useful fMRI tool for obtaining temporal information at a time scale closer to that of neuronal dynamics...
  16. pmc Dynamic oscillatory processes governing cued orienting and allocation of auditory attention
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA
    J Cogn Neurosci 25:1926-43. 2013
    ..Our results reveal sustained oscillatory patterns associated with voluntary engagement of auditory spatial attention, with the frontoparietal and temporal gamma increases being best predictors of subsequent behavioral performance. ..
  17. ncbi request reprint EEG/(f)MRI measurements at 7 Tesla using a new EEG cap ("InkCap")
    Christos E Vasios
    Harvard Medical School, Massachusetts General Hospital, Athinoula A Martinos Center for Biomedical Imaging, Building 149, 13th Street, Charlestown 02129, USA
    Neuroimage 33:1082-92. 2006
    ..Our results show that the InkCap technology considerably improves the quality of both EEG and (f)MRI during concurrent measurements even at 7 T...
  18. pmc Distinct cortical networks activated by auditory attention and working memory load
    Samantha Huang
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA Electronic address
    Neuroimage 83:1098-108. 2013
    ..Our results suggest a double dissociation between auditory attention and working memory in subregions of anterior DLPFC vs. middle lateral PFC/IFC in humans, respectively, in the context of substantially overlapping circuits. ..
  19. ncbi request reprint Impaired temporal lobe processing of preattentive auditory discrimination in schizophrenia
    Eero Pekkonen
    Department of Neurology, University of Helsinki, Finland
    Schizophr Bull 28:467-74. 2002
    ..These results suggest that patients with schizophrenia have impaired auditory processing in the temporal lobes underlying preattentive stimulus discrimination that is also selectively delayed in the left hemisphere...
  20. ncbi request reprint Dopamine modulates involuntary attention shifting and reorienting: an electromagnetic study
    Seppo Kahkonen
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
    Clin Neurophysiol 113:1894-902. 2002
    ..Dopaminergic function has been closely associated with attentional performance, but its precise role has remained elusive...
  21. ncbi request reprint Serotonin modulates early cortical auditory processing in healthy subjects: evidence from MEG with acute tryptophan depletion
    Seppo Kahkonen
    BioMag Laboratory, Engineering Centre, Helsinki University Central Hospital, Helsinki, Finland
    Neuropsychopharmacology 27:862-8. 2002
    ..The results suggest that the neurotransmitter serotonin is involved in early auditory cortical processing. Further, the serotonin modulation may be different in males and females...
  22. ncbi request reprint Acute tryptophan depletion decreases intensity dependence of auditory evoked magnetic N1/P2 dipole source activity
    Seppo Kahkonen
    BioMag Laboratory, Engineering Centre, Helsinki University Central Hospital, P O Box 340, 00029 HUS, Finland
    Psychopharmacology (Berl) 164:221-7. 2002
    ..Depletion of tryptophan (TRP), a precursor for serotonin has been described to reduce serotonin content in brain of animals and humans...
  23. ncbi request reprint Cholinergic modulation of preattentive auditory processing in aging
    Eero Pekkonen
    Department of Neurology, University of Helsinki, PO Box 340, FIN 00029 HUS, Finland
    Neuroimage 27:387-92. 2005
    ..The combined MEG/EEG measurements using particularly auditory N100 response might offer an objective tool to monitor cholinergic activity in aging and Alzheimer's disease (AD)...
  24. ncbi request reprint Tryptophan depletion effects on EEG and MEG responses suggest serotonergic modulation of auditory involuntary attention in humans
    Jyrki Ahveninen
    Cognitive Brain Research Unit, Department of Psychology, P O Box 13, University of Helsinki, Helsinki, FIN 00014, Finland
    Neuroimage 16:1052-61. 2002
    ..In conclusion, the results suggest that decreased level of central 5-HT function after ATD may decrease involuntary attention shifting to task-irrelevant sound changes and thus modulate resource allocation to the task-relevant activity...
  25. ncbi request reprint Memory-based comparison process not attenuated by haloperidol: a combined MEG and EEG study
    Eero Pekkone
    Department of Neurology, Medical Engineering Centre, Helsinki University Central Hospital, Finland
    Neuroreport 13:177-81. 2002
    ..Our results indicate that memory-based sound comparison and preceding cortical processing underlying stimulus detection are not attenuated by haloperidol, whereas haloperidol appears to accelerate preattentive sound comparison...
  26. ncbi request reprint Auditory selective attention modulated by tryptophan depletion in humans
    Jyrki Ahveninen
    Department of Psychology, PO Box 9, FIN 00014 University of Helsinki, Helsinki, Finland
    Neurosci Lett 340:181-4. 2003
    ..The P50 latencies were increased after ATD, irrespective of attention. In conclusion, serotonin may regulate attentional modulation of early cortical stimulus processing...
  27. ncbi request reprint Acute tryptophan depletion does not change somatosensory evoked magnetic fields
    Seppo Kahkonen
    Cognitive Brain Research Unit, University of Helsinki, Helsinki, Finland
    Psychopharmacology (Berl) 170:332-3. 2003
    ..Serotonin is shown to regulate the activity of primary auditory cortex, but little is known about serotonin modulation of other sensory cortices...
  28. ncbi request reprint Effects of scopolamine on MEG spectral power and coherence in elderly subjects
    Daria Osipova
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 9 00014, Helsinki, Finland
    Clin Neurophysiol 114:1902-7. 2003
    ..In order to test the sensitivity of spectral power and hemispheric coherence to changes in cholinergic transmission, we evaluated quantitative magnetoencephalogram (MEG) after intravenous injection of scopolamine...
  29. ncbi request reprint Serotonergic modulation of mismatch negativity
    Seppo Kahkonen
    Cognitive Brain Research Unit, University of Helsinki, Finland
    Psychiatry Res 138:61-74. 2005
    ..No effects on P50 were observed. The present results suggest serotonergic modulation of preattentive auditory change detection, suggested to initiate involuntary attention shifting in the human brain...
  30. ncbi request reprint Enhanced magnetic auditory steady-state response in early Alzheimer's disease
    Daria Osipova
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
    Clin Neurophysiol 117:1990-5. 2006
    ..We studied the auditory steady-state response (SSR) which represents the net effect of entrained background activity and superimposed cortical evoked responses, in AD patients and healthy controls...
  31. ncbi request reprint Adaptation of neuromagnetic N1 responses to phonetic stimuli by visual speech in humans
    Iiro P Jaaskelainen
    Laboratory of Computational Engineering, Helsinki University of Technology, Espoo, P O Box 9203, Innopoli 2, Tekniikant 14, FIN 02015 HUT Finland
    Neuroreport 15:2741-4. 2004
    ..This suggests that seeing articulatory gestures of a speaker influences auditory speech perception by modulating the responsiveness of auditory-cortex neurons...
  32. ncbi request reprint Effects of an acute D2-dopaminergic blockade on the somatosensory cortical responses in healthy humans: evidence from evoked magnetic fields
    Juha Huttunen
    BioMag Laboratory, Medical Engineering Centre Department of Clinical Neurophysiology, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS
    Neuroreport 14:1609-12. 2003
    ..05). Responses arising from SII were not significantly changed. The results suggest that dopaminergic activity may be involved in modulating somatosensory processing after the initial stages of cortical activation...
  33. ncbi request reprint Impaired pre-attentive auditory processing in opioid dependence with and without benzodiazepine co-dependence revealed by combined magnetoencephalography and electroencephalography
    Reetta Kivisaari
    Medical Imaging Centre, Box 281, Helsinki University Central Hospital, 00029 HUS, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 31:1378-86. 2007
    ..There were no group differences in EEG amplitude measures. In conclusion, our results suggest delayed pre-attentive auditory processing of novel information in opioid dependence. Benzodiazepine co-dependence modulated N1m response...
  34. ncbi request reprint Short-term plasticity in auditory cognition
    Iiro P Jaaskelainen
    Laboratory of Computational Engineering, Helsinki University of Technology, FIN 02015 TKK, Espoo, Finland
    Trends Neurosci 30:653-61. 2007
    ....
  35. ncbi request reprint Aging and cholinergic modulation of the transient magnetic 40-Hz auditory response
    Jyrki Ahveninen
    Cognitive Brain Research Unit, Department of Neurology, University of Helsinki, FIN 00014 Helsinki, Finland
    Neuroimage 15:153-8. 2002
    ..In sum, the transient magnetic 40-Hz auditory response may be useful in studies on brain cholinergic deficits in elderly subjects...
  36. pmc Dysfunction in early auditory processing in major depressive disorder revealed by combined MEG and EEG
    Seppo Kahkonen
    BioMag Laboratory, Helsinki University Central Hospital and the Cognitive Brain Research Unit, University of Helsinki, Helsinky, Finland
    J Psychiatry Neurosci 32:316-22. 2007
    ..We investigated whether MDD affects neural mechanisms of involuntary attention studied by auditory evoked potentials (AEPs) and auditory evoked magnetic fields (AEFs)...
  37. ncbi request reprint Source estimation of spontaneous MEG oscillations in mild cognitive impairment
    Daria Osipova
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
    Neurosci Lett 405:57-61. 2006
    ..Deficits in the distribution of oscillatory sources in the resting state are thus likely to occur at later stages of cognitive impairment than MCI...
  38. ncbi request reprint Altered generation of spontaneous oscillations in Alzheimer's disease
    Daria Osipova
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
    Neuroimage 27:835-41. 2005
    ....

Research Grants2

  1. Dynamic imaging of oscillatory brain networks controlling selective attention
    Jyrki Ahveninen; Fiscal Year: 2010
    ..Our results may also support investigation of disorders with abnormal cognitive control functions. ..
  2. Dynamic imaging of oscillatory brain networks controlling selective attention
    Jyrki Ahveninen; Fiscal Year: 2011
    ..Our results may also support investigation of disorders with abnormal cognitive control functions. ..