Michael C Stevens

Summary

Affiliation: Hartford Hospital
Country: USA

Publications

  1. pmc Functional neural networks underlying response inhibition in adolescents and adults
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Hartford, CT 06106, United
    Behav Brain Res 181:12-22. 2007
  2. doi request reprint Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives
    Pawel Skudlarski
    Olin Neuropsychiatry Research Center, Hartford Hospital Institute of Living, Hartford, Conn, USA
    Am J Psychiatry 170:886-98. 2013
  3. pmc Brain network dynamics during error commission
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 30:24-37. 2009
  4. pmc Is aberrant functional connectivity a psychosis endophenotype? A resting state functional magnetic resonance imaging study
    Sabin Khadka
    Olin Neuropsychiatry Research Center, Hartford Hospital Institute of Living, Hartford, CT 06106, USA
    Biol Psychiatry 74:458-66. 2013
  5. pmc Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, United States of America
    PLoS ONE 4:e7911. 2009
  6. pmc A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living, 200 Retreat Avenue, Hartford, CT 06106, USA
    Neuroimage 53:1007-15. 2010
  7. ncbi request reprint Functional neural circuits for mental timekeeping
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 28:394-408. 2007
  8. pmc Brain connectivity is not only lower but different in schizophrenia: a combined anatomical and functional approach
    Pawel Skudlarski
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut 06106, USA
    Biol Psychiatry 68:61-9. 2010
  9. pmc Robust changes in reward circuitry during reward loss in current and former cocaine users during performance of a monetary incentive delay task
    Krishna T Patel
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut Electronic address
    Biol Psychiatry 74:529-37. 2013
  10. pmc Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors
    Melissa M Andrews
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, USA
    Biol Psychiatry 69:675-83. 2011

Collaborators

Detail Information

Publications44

  1. pmc Functional neural networks underlying response inhibition in adolescents and adults
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Hartford, CT 06106, United
    Behav Brain Res 181:12-22. 2007
    ..We identify and characterize several age-related differences in the function of neural circuits that are associated with behavioral performance changes across adolescent development...
  2. doi request reprint Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives
    Pawel Skudlarski
    Olin Neuropsychiatry Research Center, Hartford Hospital Institute of Living, Hartford, Conn, USA
    Am J Psychiatry 170:886-98. 2013
    ..CONCLUSIONS Fractional anisotropy was highly heritable, supporting its value as a potential endophenotype. ..
  3. pmc Brain network dynamics during error commission
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 30:24-37. 2009
    ..These findings characterize the spatial structure of neural networks underlying error commission and identify neurobiological differences between adolescents and adults...
  4. pmc Is aberrant functional connectivity a psychosis endophenotype? A resting state functional magnetic resonance imaging study
    Sabin Khadka
    Olin Neuropsychiatry Research Center, Hartford Hospital Institute of Living, Hartford, CT 06106, USA
    Biol Psychiatry 74:458-66. 2013
    ..Schizophrenia and bipolar disorder share overlapping symptoms and risk genes. Shared aberrant functional connectivity is hypothesized in both disorders and in relatives...
  5. pmc Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, United States of America
    PLoS ONE 4:e7911. 2009
    ..Numerous neuroimaging studies report abnormal regional brain activity during working memory performance in schizophrenia, but few have examined brain network integration as determined by "functional connectivity" analyses...
  6. pmc A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living, 200 Retreat Avenue, Hartford, CT 06106, USA
    Neuroimage 53:1007-15. 2010
    ....
  7. ncbi request reprint Functional neural circuits for mental timekeeping
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 28:394-408. 2007
    ..These findings are discussed within the context of current biological and information processing models of neural timekeeping...
  8. pmc Brain connectivity is not only lower but different in schizophrenia: a combined anatomical and functional approach
    Pawel Skudlarski
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut 06106, USA
    Biol Psychiatry 68:61-9. 2010
    ..Simultaneous measure of anatomical and functional connectivity and its interactions allow for better understanding of schizophrenia-related alternations in brain connectivity...
  9. pmc Robust changes in reward circuitry during reward loss in current and former cocaine users during performance of a monetary incentive delay task
    Krishna T Patel
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut Electronic address
    Biol Psychiatry 74:529-37. 2013
    ..Abnormal function in reward circuitry in cocaine addiction could predate drug use as a risk factor, follow drug use as a consequence of substance-induced alterations, or both...
  10. pmc Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors
    Melissa M Andrews
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, USA
    Biol Psychiatry 69:675-83. 2011
    ..However, there is limited information on whether this uncharacteristic behavior represents a biological predisposition toward alcohol abuse, a consequence of chronic alcohol use, or both...
  11. ncbi request reprint An FMRI auditory oddball study of combined-subtype attention deficit hyperactivity disorder
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Whitehall Building, Institute of Living Hartford Hospital, Hartford, CT 06106, USA
    Am J Psychiatry 164:1737-49. 2007
    ..However, the relationship between abnormal neurocognition and dysfunction in specific brain regions in ADHD remains unclear...
  12. pmc The hemodynamics of oddball processing during single-tone and two-tone target detection tasks
    Michael C Stevens
    Clinical Cognitive Neuroscience Laboratory, Olin Neuropsychiatry Research Center, Whitehall Building, The Institute of Living Hartford Hospital, CT 06106, USA
    Int J Psychophysiol 60:292-303. 2006
    ..The results are discussed as they relate to the understanding of neurocognitive function pertaining to contextual manipulations in general, and orienting processes in particular...
  13. pmc Cortical thickness and folding deficits in conduct-disordered adolescents
    Christopher J Hyatt
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, USA
    Biol Psychiatry 72:207-14. 2012
    ..On the basis of current frontotemporal theories, we hypothesized that CD youth would have thinner cortex or less cortical folding in temporal and frontal lobes than control subjects...
  14. pmc Influence of alcohol use on neural response to Go/No-Go task in college drinkers
    Aral Ahmadi
    Olin Neuropsychiatry Research Center, Hartford Hospital Institute of Living, Hartford, CT, USA
    Neuropsychopharmacology 38:2197-208. 2013
    ..The extent to which these tendencies relate to impulsive decision-making and behaviors in real-life settings and may guide intervention development warrants additional investigation. ..
  15. ncbi request reprint Default mode network activity and white matter integrity in healthy middle-aged ApoE4 carriers
    Krishna T Patel
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, CT 06106, USA
    Brain Imaging Behav 7:60-7. 2013
    ..Our findings suggest that functional MRI abnormalities may be detectable well before cognitive decline or white matter changes among individuals at increased genetic risk for AD...
  16. ncbi request reprint An adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task
    Kent A Kiehl
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT 06106, USA
    Neuroimage 25:899-915. 2005
    ..This process may be termed 'adaptive reflexive processing.' The implications of these results for interpreting functional MRI studies are discussed...
  17. pmc Abnormal hemodynamics in schizophrenia during an auditory oddball task
    Kent A Kiehl
    Clinical Cognitive Neuroscience Laboratory, Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, Connecticut 06106, USA
    Biol Psychiatry 57:1029-40. 2005
    ..This deficit in the processing of salience stimuli might be related to abnormalities in orienting, attention, and memory processes...
  18. doi request reprint Decreased prefrontal cortex activity in mild traumatic brain injury during performance of an auditory oddball task
    Suzanne T Witt
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, CT 06106, USA
    Brain Imaging Behav 4:232-47. 2010
    ..Between-group analyses found evidence for potential compensatory brain activity during target detection and default-mode network dysfunction only during the detection of novel stimuli...
  19. pmc Abnormal functional connectivity of default mode sub-networks in autism spectrum disorder patients
    Michal Assaf
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, CT 06106, USA
    Neuroimage 53:247-56. 2010
    ..This approach seems especially well suited for populations where compliance with and performance of active tasks might be a challenge, as it requires minimal cooperation...
  20. pmc Comparison of brain volume abnormalities between ADHD and conduct disorder in adolescence
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, CT 06106, USA
    J Psychiatry Neurosci 37:389-98. 2012
    ..To our knowledge, this study was the first direct comparison of grey and white matter volumes in diagnostically "pure" (i.e., no comorbidities) conduct disorder and ADHD samples...
  21. pmc The role of top-down control in different phases of a sensorimotor timing task: a DCM study of adults and adolescents
    Suzanne T Witt
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, 200 Retreat Avenue, ONRC, Whitehall Building, Hartford, CT, 06106, USA
    Brain Imaging Behav 7:260-73. 2013
    ..Both right and left prefrontal cortex were found to exert control over timing behavioral accuracy, but there were distinctly lateralized roles with respect to optimal performance. ..
  22. pmc Effects of memantine on event-related potential, oscillations, and complexity in individuals with and without family histories of alcoholism
    Balaji Narayanan
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    J Stud Alcohol Drugs 74:245-57. 2013
    ....
  23. pmc A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort
    Shashwath A Meda
    Olin Neuropsychiatric Research Center, Hartford Hospital IOL, Hartford, CT 06106, USA
    Neuroimage 60:1608-21. 2012
    ..Further, the study exemplifies the value of this novel approach to explore large-scale data sets involving high-dimensional gene and endophenotype data...
  24. pmc Genetic associations of brain structural networks in schizophrenia: a preliminary study
    Kanchana Jagannathan
    Olin Neuropsychiatry Research Center, Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
    Biol Psychiatry 68:657-66. 2010
    ..We used structural parameters as potential intermediate illness markers to investigate genomic factors derived from single nucleotide polymorphism (SNP) arrays...
  25. ncbi request reprint Changes in the interaction of resting-state neural networks from adolescence to adulthood
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 30:2356-66. 2009
    ..These results contribute to an emerging understanding that activity in widely distributed networks thought to underlie complex cognition influences activity in other networks...
  26. pmc Age-related cognitive gains are mediated by the effects of white matter development on brain network integration
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Whitehall Building, The Institute of Living Hartford Hospital, Hartford, CT 06106, USA
    Neuroimage 48:738-46. 2009
    ....
  27. ncbi request reprint fMRI in an oddball task: effects of target-to-target interval
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, Connecticut 06106, USA
    Psychophysiology 42:636-42. 2005
    ..There was no such effect of novel interval, suggesting that neuronal modulation may only occur for task-relevant stimuli, possibly in the service of strategic resource allocation processes...
  28. pmc Hemispheric differences in hemodynamics elicited by auditory oddball stimuli
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT 06106, USA Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Neuroimage 26:782-92. 2005
    ..The results (1) support the proposal that the right hemisphere is differentially engaged in processing salient stimuli and (2) demonstrate the successful use of a new voxel-based laterality analysis technique for fMRI data...
  29. pmc Prolonged hemodynamic response during incidental facial emotion processing in inter-episode bipolar I disorder
    Ethan S Rosenfeld
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, 200 Retreat Ave, Whitehall Building, Hartford, CT, 06106, USA
    Brain Imaging Behav 8:73-86. 2014
    ....
  30. pmc Neuroinformatics Database (NiDB)--a modular, portable database for the storage, analysis, and sharing of neuroimaging data
    Gregory A Book
    Olin Neuropsychiatry Research Center, Hartford Hospital, Hartford, CT, USA
    Neuroinformatics 11:495-505. 2013
    ..NiDB not only simplifies the local storage and analysis of neuroimaging data, but also enables simple sharing of raw data and analysis methods, which may encourage further sharing. ..
  31. pmc Overcoming residual interference in mental set switching: neural correlates and developmental trajectory
    Suzanne T Witt
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, CT 06106, USA
    Neuroimage 62:2055-64. 2012
    ..These novel findings represent a new avenue of exploration of cognitive set switching neural function...
  32. pmc Differences in resting-state functional magnetic resonance imaging functional network connectivity between schizophrenia and psychotic bipolar probands and their unaffected first-degree relatives
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Hartford Hospital Institute of Living, Hartford, Connecticut 06106, USA
    Biol Psychiatry 71:881-9. 2012
    ..Schizophrenia and bipolar disorder share overlapping symptoms and genetic etiology. Functional brain dysconnectivity is seen in both disorders...
  33. pmc Disruptions in functional network connectivity during alcohol intoxicated driving
    Catherine I Rzepecki-Smith
    Olin Neuropsychiatry Research Center, Institute of Living Hartford Hospital, Hartford, Connecticut, USA
    Alcohol Clin Exp Res 34:479-87. 2010
    ..However, the functional connectivity between these circuits has not yet been explored in order to determine how these networks communicate with each other during sober and alcohol-intoxicated states...
  34. pmc fMRI task parameters influence hemodynamic activity in regions implicated in mental set switching
    Suzanne T Witt
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, 200 Retreat Avenue, ONRC, Whitehall Building, Hartford, CT 06106, USA
    Neuroimage 65:139-51. 2013
    ....
  35. ncbi request reprint The effects of stimulant medication on working memory functional connectivity in attention-deficit/hyperactivity disorder
    Christina G Wong
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
    Biol Psychiatry 71:458-66. 2012
    ..This study used functional magnetic resonance imaging (fMRI) to examine medication-related changes in brain activation and functional connectivity in ADHD...
  36. ncbi request reprint Low-dose estradiol alters brain activity
    Michael C Stevens
    Clinical Cognitive Neuroscience Laboratory, Olin Neuropsychiatry Research Center, Whitehall Building, The Institute of Living Hartford Hospital, Hartford, CT 06106, USA
    Psychiatry Res 139:199-217. 2005
    ..These findings suggest that estrogen may facilitate the efficiency of brain function during the performance of sustained attention tasks in post-menopausal elderly women...
  37. pmc Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut 06106, USA
    Behav Pharmacol 20:390-9. 2009
    ..In addition, our supplemental analysis also suggested that the impulsivity constructs were largely, but not entirely the same within the healthy and ARA groups...
  38. ncbi request reprint The developmental cognitive neuroscience of functional connectivity
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, 200 Retreat Avenue, Whitehall Building, Hartford, CT 06106, USA
    Brain Cogn 70:1-12. 2009
    ..Although not exhaustive, this conceptual review also will showcase some of recent findings that have emerged to support these predictions...
  39. pmc Hoarding disorder and obsessive-compulsive disorder show different patterns of neural activity during response inhibition
    David F Tolin
    The Institute of Living and Yale University School of Medicine, 200 Retreat Avenue, Hartford, CT 06106, USA Electronic address
    Psychiatry Res 221:142-8. 2014
    ..The present results lend further support to the biological distinction between HD and OCD, and they are consistent with previous research suggesting frontal hypoactivity in HD patients during hoarding-unrelated tasks. ..
  40. pmc DTI-measured white matter abnormalities in adolescents with Conduct Disorder
    Emily Haney-Caron
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, 200 Retreat Avenue, Hartford, CT 06106, USA
    J Psychiatr Res 48:111-20. 2014
    ..Instead, neurobiological risk specific to antisociality in adolescence is linked to microstructural abnormality in numerous long-range white matter connections among many diverse different brain regions...
  41. doi request reprint Multiple resting state network functional connectivity abnormalities in mild traumatic brain injury
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, CT, USA
    Brain Imaging Behav 6:293-318. 2012
    ....
  42. ncbi request reprint Functional neuroimaging in child and adolescent psychiatry
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, USA
    Conn Med 69:561-70. 2005
  43. ncbi request reprint The effect of short-term estradiol therapy on cognitive function in older men receiving hormonal suppression therapy for prostate cancer
    Pamela Taxel
    Division of Endocrinology and Metabolism and Center on Aging, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Am Geriatr Soc 52:269-73. 2004
    ....
  44. ncbi request reprint Executive-cognitive functioning in the development of antisocial personality disorder
    Michael C Stevens
    Department of Psychiatry, MC2103, University of Connecticut Health Center, Farmington, CT 06030, USA
    Addict Behav 28:285-300. 2003
    ..The findings suggest that normal versus abnormal behavioral outcome for children with conduct problems may be influenced by cognitive ability profile, perhaps because of varying maturational processes...