Shashwath A Meda

Summary

Affiliation: Hartford Hospital
Country: USA

Publications

  1. ncbi Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, United States of America
    PLoS ONE 4:e7911. 2009
  2. ncbi A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living, 200 Retreat Avenue, Hartford, CT 06106, USA
    Neuroimage 53:1007-15. 2010
  3. ncbi Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut 06106, USA
    Behav Pharmacol 20:390-9. 2009
  4. ncbi An fMRI study of working memory in first-degree unaffected relatives of schizophrenia patients
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, CT 06106, USA
    Schizophr Res 104:85-95. 2008
  5. ncbi Alcohol dose effects on brain circuits during simulated driving: an fMRI study
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Connecticut, USA
    Hum Brain Mapp 30:1257-70. 2009
  6. ncbi A large scale (N=400) investigation of gray matter differences in schizophrenia using optimized voxel-based morphometry
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, CT 06106, USA
    Schizophr Res 101:95-105. 2008
  7. ncbi Functional imaging of cognitive control during acute alcohol intoxication
    Beth M Anderson
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Connecticut, USA
    Alcohol Clin Exp Res 35:156-65. 2011
  8. ncbi Effects of alcohol on performance on a distraction task during simulated driving
    Allyssa J Allen
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, Connecticut 06106, USA
    Alcohol Clin Exp Res 33:617-25. 2009
  9. ncbi Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors
    Melissa M Andrews
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, USA
    Biol Psychiatry 69:675-83. 2011
  10. ncbi Diffusion tensor imaging in schizophrenia: relationship to symptoms
    Laurie R Skelly
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
    Schizophr Res 98:157-62. 2008

Detail Information

Publications15

  1. ncbi Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, United States of America
    PLoS ONE 4:e7911. 2009
    ..Numerous neuroimaging studies report abnormal regional brain activity during working memory performance in schizophrenia, but few have examined brain network integration as determined by "functional connectivity" analyses...
  2. ncbi A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living, 200 Retreat Avenue, Hartford, CT 06106, USA
    Neuroimage 53:1007-15. 2010
    ....
  3. ncbi Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut 06106, USA
    Behav Pharmacol 20:390-9. 2009
    ..In addition, our supplemental analysis also suggested that the impulsivity constructs were largely, but not entirely the same within the healthy and ARA groups...
  4. ncbi An fMRI study of working memory in first-degree unaffected relatives of schizophrenia patients
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, CT 06106, USA
    Schizophr Res 104:85-95. 2008
    ..Additionally, fMRI differences in both conditions were modulated by load, with a parametric increase in between-group differences with load in several key regions during encoding and an opposite effect during response selection...
  5. ncbi Alcohol dose effects on brain circuits during simulated driving: an fMRI study
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Connecticut, USA
    Hum Brain Mapp 30:1257-70. 2009
    ..Overall, results suggest that alcohol (especially at high doses) causes significant impairment of both driving behavior and brain functionality related to motor planning and control, goal directedness, error monitoring, and memory...
  6. ncbi A large scale (N=400) investigation of gray matter differences in schizophrenia using optimized voxel-based morphometry
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, CT 06106, USA
    Schizophr Res 101:95-105. 2008
    ..However, results from these studies vary widely, likely due to different methodological or statistical approaches...
  7. ncbi Functional imaging of cognitive control during acute alcohol intoxication
    Beth M Anderson
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Connecticut, USA
    Alcohol Clin Exp Res 35:156-65. 2011
    ..The effects of different doses of alcohol on activity within these brain regions during a functional magnetic resonance imaging (fMRI) task where errors are frequently committed have not been fully explored...
  8. ncbi Effects of alcohol on performance on a distraction task during simulated driving
    Allyssa J Allen
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, Connecticut 06106, USA
    Alcohol Clin Exp Res 33:617-25. 2009
    ..Previous functional MRI (fMRI) studies of the VO task have shown activation in the anterior cingulate, hippocampus, and prefrontal cortex. Thus, we predicted dose-dependent decreases in activation of these areas during VO performance...
  9. ncbi Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors
    Melissa M Andrews
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, USA
    Biol Psychiatry 69:675-83. 2011
    ..However, there is limited information on whether this uncharacteristic behavior represents a biological predisposition toward alcohol abuse, a consequence of chronic alcohol use, or both...
  10. ncbi Diffusion tensor imaging in schizophrenia: relationship to symptoms
    Laurie R Skelly
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
    Schizophr Res 98:157-62. 2008
    ....
  11. ncbi Disruptions in functional network connectivity during alcohol intoxicated driving
    Catherine I Rzepecki-Smith
    Olin Neuropsychiatry Research Center, Institute of Living Hartford Hospital, Hartford, Connecticut, USA
    Alcohol Clin Exp Res 34:479-87. 2010
    ..However, the functional connectivity between these circuits has not yet been explored in order to determine how these networks communicate with each other during sober and alcohol-intoxicated states...
  12. ncbi A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort
    Shashwath A Meda
    Olin Neuropsychiatric Research Center, Hartford Hospital IOL, Hartford, CT 06106, USA
    Neuroimage 60:1608-21. 2012
    ..Further, the study exemplifies the value of this novel approach to explore large-scale data sets involving high-dimensional gene and endophenotype data...
  13. ncbi Differences in resting-state functional magnetic resonance imaging functional network connectivity between schizophrenia and psychotic bipolar probands and their unaffected first-degree relatives
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Hartford Hospital Institute of Living, Hartford, Connecticut 06106, USA
    Biol Psychiatry 71:881-9. 2012
    ..Schizophrenia and bipolar disorder share overlapping symptoms and genetic etiology. Functional brain dysconnectivity is seen in both disorders...
  14. ncbi Genetic influences of resting state fMRI activity in language-related brain regions in healthy controls and schizophrenia patients: a pilot study
    Sharna Jamadar
    Olin Neuropsychiatry Research Center, Institute of Living, 200 Retreat Ave, Hartford, CT 06106, USA
    Brain Imaging Behav 7:15-27. 2013
    ..Thus these RD-genes may exert a more important influence on structure rather than function of language-related networks in schizophrenia...
  15. ncbi Global white matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury
    Randall R Benson
    Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Neurotrauma 24:446-59. 2007
    ..FA is globally deceased in WM, including mild TBI, possibly reflecting widespread involvement. FA changes appear to be correlated with injury severity suggesting a role in early diagnosis and prognosis of TBI...