C Wang

Summary

Affiliation: Harbor-UCLA Medical Center
Country: USA

Publications

  1. ncbi request reprint Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study
    C Wang
    Department of Medicine, Harbor University of California Los Angeles Medical Center, Torrance 90509 2910, USA
    J Clin Endocrinol Metab 81:3654-62. 1996
  2. ncbi request reprint Oligozoospermia induced by exogenous testosterone is associated with normal functioning residual spermatozoa
    C Wang
    Department of Medicine, Harbor University of California Los Angeles Medical Center, Torrance 90509, USA
    Fertil Steril 68:149-53. 1997
  3. ncbi request reprint Effect of increased scrotal temperature on sperm production in normal men
    C Wang
    Department of Medicine, Harbor University of California, Los Angeles Medical Center, Torrance 90509 2910, USA
    Fertil Steril 68:334-9. 1997
  4. ncbi request reprint Androgen replacement therapy
    C Wang
    Department of Medicine, Harbor UCLA Medical Center, Torrance, California 90509 2910, USA
    Ann Med 29:365-70. 1997
  5. ncbi request reprint Graded testosterone infusions distinguish gonadotropin negative-feedback responsiveness in Asian and white men--a Clinical Research Center study
    C Wang
    Department of Medicine, Harbor UCLA Medical Center, Torrance, California 90509, USA
    J Clin Endocrinol Metab 83:870-6. 1998
  6. ncbi request reprint Comparative pharmacokinetics of three doses of percutaneous dihydrotestosterone gel in healthy elderly men--a clinical research center study
    C Wang
    Department of Medicine, Harbor UCLA Medical Center, Torrance, California 90509 2910, USA
    J Clin Endocrinol Metab 83:2749-57. 1998
  7. ncbi request reprint Pharmacokinetics of transdermal testosterone gel in hypogonadal men: application of gel at one site versus four sites: a General Clinical Research Center Study
    C Wang
    Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, Torrance, California 90509, USA
    J Clin Endocrinol Metab 85:964-9. 2000
  8. ncbi request reprint Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men
    C Wang
    Divisions of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, Torrance, CA, USA
    Clin Endocrinol (Oxf) 54:739-50. 2001
  9. ncbi request reprint Myocardial creatine kinase kinetics and isoform expression in hearts with severe LV hypertrophy
    Y Ye
    Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Am J Physiol Heart Circ Physiol 281:H376-86. 2001
  10. doi request reprint Transplanted XY germ cells produce spermatozoa in testes of XXY mice
    Y Lue
    Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Int J Androl 33:581-7. 2010

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study
    C Wang
    Department of Medicine, Harbor University of California Los Angeles Medical Center, Torrance 90509 2910, USA
    J Clin Endocrinol Metab 81:3654-62. 1996
    ....
  2. ncbi request reprint Oligozoospermia induced by exogenous testosterone is associated with normal functioning residual spermatozoa
    C Wang
    Department of Medicine, Harbor University of California Los Angeles Medical Center, Torrance 90509, USA
    Fertil Steril 68:149-53. 1997
    ..To determine the functional capacity of residual spermatozoa in semen samples from normal men with T enanthate-induced oligozoospermia...
  3. ncbi request reprint Effect of increased scrotal temperature on sperm production in normal men
    C Wang
    Department of Medicine, Harbor University of California, Los Angeles Medical Center, Torrance 90509 2910, USA
    Fertil Steril 68:334-9. 1997
    ..To determine whether application of polyester-lined athletic supports to bring the testes closer to the abdomen increases scrotal temperature and decreases sperm production...
  4. ncbi request reprint Androgen replacement therapy
    C Wang
    Department of Medicine, Harbor UCLA Medical Center, Torrance, California 90509 2910, USA
    Ann Med 29:365-70. 1997
    ..In the future, designer androgens with specific beneficial effect on sexual function, mood, bone and muscle mass but with attenuated effects on serum lipid profiles and the prostate gland may be developed...
  5. ncbi request reprint Graded testosterone infusions distinguish gonadotropin negative-feedback responsiveness in Asian and white men--a Clinical Research Center study
    C Wang
    Department of Medicine, Harbor UCLA Medical Center, Torrance, California 90509, USA
    J Clin Endocrinol Metab 83:870-6. 1998
    ..Whether these differences contribute to the observed differences in suppression of spermatogenesis in Asians vs. non-Asians in male contraceptive studies is not yet known...
  6. ncbi request reprint Comparative pharmacokinetics of three doses of percutaneous dihydrotestosterone gel in healthy elderly men--a clinical research center study
    C Wang
    Department of Medicine, Harbor UCLA Medical Center, Torrance, California 90509 2910, USA
    J Clin Endocrinol Metab 83:2749-57. 1998
    ..0001) on both days 1 and 14. We conclude that the three doses of DHT gel tested might provide adequate androgen replacement in hypogonadal men at the low, middle, and high physiological androgen (T + DHT) range...
  7. ncbi request reprint Pharmacokinetics of transdermal testosterone gel in hypogonadal men: application of gel at one site versus four sites: a General Clinical Research Center Study
    C Wang
    Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, Torrance, California 90509, USA
    J Clin Endocrinol Metab 85:964-9. 2000
    ..Dose-ranging studies are required to determine dosage regimens for T gel application as a replacement therapy in hypogonadal men...
  8. ncbi request reprint Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men
    C Wang
    Divisions of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, Torrance, CA, USA
    Clin Endocrinol (Oxf) 54:739-50. 2001
    ..Androgen replacement has been reported to increase bone mineral density (BMD) in hypogonadal men. We studied the effects of 6 months of treatment with a new transdermal testosterone (T) gel preparation on bone turnover markers and BMD...
  9. ncbi request reprint Myocardial creatine kinase kinetics and isoform expression in hearts with severe LV hypertrophy
    Y Ye
    Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Am J Physiol Heart Circ Physiol 281:H376-86. 2001
    ..However, myocardial free ADP was increased in LVH hearts. This finding suggests that the CK alterations result in a need for higher ADP levels to maintain ATP synthesis in the hypertrophied heart...
  10. doi request reprint Transplanted XY germ cells produce spermatozoa in testes of XXY mice
    Y Lue
    Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Int J Androl 33:581-7. 2010
    ..The results demonstrated that the donor XY germ cells were able to qualitatively complete spermatogenesis in some of the seminiferous tubules of XXY mice...
  11. ncbi request reprint Transdermal androgens: pharmacology and applicability to hypogonadal elderly men
    R S Swerdloff
    Division of Endocrinology, Department of Medicine Harbor UCLA Medical Center and Los Angeles Biomedical Research Center, Torrance 90509, USA
    J Endocrinol Invest 28:112-6. 2005
    ....
  12. ncbi request reprint Suppression of spermatogenesis in man induced by Nal-Glu gonadotropin releasing hormone antagonist and testosterone enanthate (TE) is maintained by TE alone
    R S Swerdloff
    Department of Medicine, Harbor University of California, Los Angeles Medical Center, Torrance 90509, USA
    J Clin Endocrinol Metab 83:3527-33. 1998
    ..This concept should be explored further in the development of effective, safe, and affordable hormonal male contraceptives...
  13. ncbi request reprint Levonorgestrel implants (Norplant II) for male contraception clinical trials: combination with transdermal and injectable testosterone
    I T Gaw Gonzalo
    Division of Endocrinology, Department of Medicine, Harbor University of California at Los Angeles Medical Center and Research and Education Institute, Torrance, California 90509, USA
    J Clin Endocrinol Metab 87:3562-72. 2002
    ..This study demonstrates that the dose or route of administration of androgens is critical for sperm suppression in combined androgen-progestagen regimens for hormonal male contraception...
  14. ncbi request reprint Impairment of spermatogenesis in transgenic mice with selective overexpression of Bcl-2 in the somatic cells of the testis
    C M Yamamoto
    Department of Medicine, Harbor-UCLA Medical Center and Research and Education Institute, Torrance, California 90509, USA
    J Androl 22:981-91. 2001
    ..Collectively, these results support the critical role of Bcl-2 in male germ cell development and are consistent with the gender-specific role of the Bcl-2 family members in reproduction...
  15. ncbi request reprint Reproductive aging in the Brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement
    C Wang
    Department of Medicine, Harbor UCLA Medical Center, Torrance, California 90509 2910, USA
    J Androl 20:509-18. 1999
    ..Replacement therapy with LH for 6 months does not decrease or delay the testicular dysfunction associated with aging. It is unlikely that hypothalamic-pituitary dysregulation is the major cause of testicular aging...
  16. doi request reprint Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride
    M Y Roth
    Population Center for Research in Human Reproduction and Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Int J Androl 34:541-7. 2011
    ..Oral TU differs from other formulations of oral testosterone in its response to concomitant inhibition of 5α-reductase, perhaps because of its unique lymphatic route of absorption...
  17. ncbi request reprint XXY male mice: an experimental model for Klinefelter syndrome
    Y Lue
    Division of Endocrinology, Department of Medicine, Harbor-University of California-Los Angeles Medical Center and Research and Education Institute, Torrance, California 90509, USA
    Endocrinology 142:1461-70. 2001
    ..The XXY mouse provides an experimental model for its human XXY counterpart, Klinefelter syndrome...
  18. ncbi request reprint Three-year follow-up of androgen treatment in hypogonadal men: preliminary report with testosterone gel
    R S Swerdloff
    Swerdloff, Harbor UCLA Medical Center, Division of Endocrinology, Box 446, 1000 W Carson Street, Torrance, CA 90509 2910, USA
    Aging Male 6:207-11. 2003
    ..Monitoring for prostate disease through PSA measurements and digital rectal examination is recommended for hypogonadal men in the older age groups when treated with testosterone...
  19. ncbi request reprint Pratical aspects of testosterone substitution
    C Wang
    Division of Endocrinology, Department of Medicine Harbor UCLA Medical Center and Los Angeles Biomedical Research Center, Torrance, USA
    J Endocrinol Invest 28:109-11. 2005
    ..Monitoring for manifestations of prostate disease, erythrocytosis and other adverse events of androgen treatment is critical in the management of older men with androgen replacement therapy...
  20. ncbi request reprint Influence of pituitary disease on sexual development and functioning
    R S Swerdloff
    Division of Endocrinology, UCLA School of Medicine, Harbor UCLA Medical Center, Torrance, USA
    Psychother Psychosom 67:173-80. 1998
    ..The effects of pituitary insufficiency and pituitary adenomas on sexual development, reproductive function and sexuality in men and women are discussed...
  21. doi request reprint Obesity, low testosterone levels and erectile dysfunction
    M Diaz-Arjonilla
    Division of Endocrinology, Department of Medicine, Harbor UCLA Medical Center, Torrance, CA 90803, USA
    Int J Impot Res 21:89-98. 2009
    ..This review describes the relationships between low serum testosterone concentrations and ED in obese patients and those with metabolic syndrome and type 2 diabetes mellitus...
  22. pmc Glycemic load effect on fasting and post-prandial serum glucose, insulin, IGF-1 and IGFBP-3 in a randomized, controlled feeding study
    S S Runchey
    Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, University of Washington, Seattle, WA, USA
    Eur J Clin Nutr 66:1146-52. 2012
    ..We aimed to assess the impact of GL on concentrations of IGF-1 and IGF-binding protein-3 (IGFBP-3)...
  23. pmc The cytoprotective peptide humanin is induced and neutralizes Bax after pro-apoptotic stress in the rat testis
    Y Jia
    Division of Endocrinology, Department of Medicine, Los Angeles Biomedical Research Institute and Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
    Andrology 1:651-9. 2013
    ....
  24. doi request reprint ISA, ISSAM, EAU, EAA and ASA recommendations: investigation, treatment and monitoring of late-onset hypogonadism in males
    C Wang
    Division of Endocrinology, Department of Medicine, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Int J Impot Res 21:1-8. 2009
    ....
  25. ncbi request reprint Mitochondrial ATPase and high-energy phosphates in failing hearts
    J Liu
    Department of Medicine, University of Minnesota Health Sciences, Minneapolis, Minnesota 55455, USA
    Am J Physiol Heart Circ Physiol 281:H1319-26. 2001
    ..Thus in failing hearts, reductions in mitochondrial F(0)F(1)-ATPase protein expression are associated with increased myocardial free ADP...
  26. ncbi request reprint Cold storage induces time-dependent F2-isoprostane formation in renal tubular cells and rat kidneys
    A Salahudeen
    Department of Medicine, University of Mississippi Medical Center, Jackson, USA
    Kidney Int 55:1759-62. 1999
    ..Because free radical-induced lipid peroxidation catalyzes the cyclooxygenase-independent formation of vasoconstrictive F2-isoprostanes, the hypothesis that isoprostanes are produced during cold storage was tested in this study...