C A Haller

Summary

Country: USA

Publications

  1. ncbi Making a diagnosis of herbal-related toxic hepatitis
    Christine A Haller
    California Poison Control System and Department of Medicine, Division of Clinical Pharmacology Box 1220 University of California, San Francisco (UCSF) San Francisco, CA 94143-1220, USA
    West J Med 176:39-44. 2002
  2. ncbi Seizures reported in association with use of dietary supplements
    Christine A Haller
    University of California, San Francisco, San Francisco, California 94143, USA
    Clin Toxicol (Phila) 43:23-30. 2005
  3. ncbi St John's wort, depression, and catecholamines
    Christine A Haller
    University of California, San Francisco, CA 94143, USA
    Clin Pharmacol Ther 76:393-5. 2004
  4. ncbi Short-term metabolic and hemodynamic effects of ephedra and guarana combinations
    Christine A Haller
    Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, CA 94143, USA
    Clin Pharmacol Ther 77:560-71. 2005
  5. ncbi Concentrations of ephedra alkaloids and caffeine in commercial dietary supplements
    Christine A Haller
    University of California, San Francisco, Department of Medicine, Division of Clinical Pharmacology, San Francisco General Hospital, 1001 Potrero Avenue, Building 30, 3rd Floor, San Francisco, California 94110, USA
    J Anal Toxicol 28:145-51. 2004
  6. ncbi Enhanced stimulant and metabolic effects of combined ephedrine and caffeine
    Christine A Haller
    Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, CA 94143, USA
    Clin Pharmacol Ther 75:259-73. 2004
  7. ncbi An evaluation of selected herbal reference texts and comparison to published reports of adverse herbal events
    Christine A Haller
    Department of Medicine and Clinical Pharmacy, University of California, San Francisco, California, USA
    Adverse Drug React Toxicol Rev 21:143-50. 2002
  8. ncbi Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use
    Christine A Haller
    Division of Clinical Pharmacology, San Francisco General Hospital, University of California, 94143, USA
    Clin Pharmacol Ther 71:421-32. 2002
  9. ncbi Comparison of an automated and point-of-care immunoassay to GC-MS for urine oxycodone testing in the clinical laboratory
    Christine A Haller
    Department of Medicine and Laboratory Medicine, University of California San Francisco, Box 1220, San Francisco, CA 94143, USA
    J Anal Toxicol 30:106-11. 2006
  10. ncbi Clinical pharmacology of 1,4-butanediol and gamma-hydroxybutyrate after oral 1,4-butanediol administration to healthy volunteers
    D Thai
    Amgen Corportion, Thousand Oaks, California, USA
    Clin Pharmacol Ther 81:178-84. 2007

Research Grants

  1. PHARMACOLOGY OF COMBINED EPHEDRINE/CAFFEINE SUPPLEMENTS
    Christine Haller; Fiscal Year: 2004

Detail Information

Publications18

  1. ncbi Making a diagnosis of herbal-related toxic hepatitis
    Christine A Haller
    California Poison Control System and Department of Medicine, Division of Clinical Pharmacology Box 1220 University of California, San Francisco (UCSF) San Francisco, CA 94143-1220, USA
    West J Med 176:39-44. 2002
  2. ncbi Seizures reported in association with use of dietary supplements
    Christine A Haller
    University of California, San Francisco, San Francisco, California 94143, USA
    Clin Toxicol (Phila) 43:23-30. 2005
    ..Seizures in persons using dietary supplements (DS) have been reported through the Food and Drug Administration's (FDA) MedWatch system, but not formally reviewed...
  3. ncbi St John's wort, depression, and catecholamines
    Christine A Haller
    University of California, San Francisco, CA 94143, USA
    Clin Pharmacol Ther 76:393-5. 2004
  4. ncbi Short-term metabolic and hemodynamic effects of ephedra and guarana combinations
    Christine A Haller
    Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, CA 94143, USA
    Clin Pharmacol Ther 77:560-71. 2005
    ..We sought to determine whether repeated dosing and multi-ingredient formulations contribute to the adverse effects of these supplements...
  5. ncbi Concentrations of ephedra alkaloids and caffeine in commercial dietary supplements
    Christine A Haller
    University of California, San Francisco, Department of Medicine, Division of Clinical Pharmacology, San Francisco General Hospital, 1001 Potrero Avenue, Building 30, 3rd Floor, San Francisco, California 94110, USA
    J Anal Toxicol 28:145-51. 2004
    ..We conclude that product inconsistency is common among some commercially available dietary supplements that contain ephedra alkaloids and caffeine...
  6. ncbi Enhanced stimulant and metabolic effects of combined ephedrine and caffeine
    Christine A Haller
    Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, CA 94143, USA
    Clin Pharmacol Ther 75:259-73. 2004
    ..We sought to determine whether ephedrine and caffeine have clinically significant pharmacologic interactions that explain these toxicities...
  7. ncbi An evaluation of selected herbal reference texts and comparison to published reports of adverse herbal events
    Christine A Haller
    Department of Medicine and Clinical Pharmacy, University of California, San Francisco, California, USA
    Adverse Drug React Toxicol Rev 21:143-50. 2002
    ..We systematically assessed six herbal reference texts to evaluate the information they contain on herbal toxicity...
  8. ncbi Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use
    Christine A Haller
    Division of Clinical Pharmacology, San Francisco General Hospital, University of California, 94143, USA
    Clin Pharmacol Ther 71:421-32. 2002
    ..We assessed the pharmacokinetics and pharmacodynamics of a dietary supplement that contains these herbal stimulants...
  9. ncbi Comparison of an automated and point-of-care immunoassay to GC-MS for urine oxycodone testing in the clinical laboratory
    Christine A Haller
    Department of Medicine and Laboratory Medicine, University of California San Francisco, Box 1220, San Francisco, CA 94143, USA
    J Anal Toxicol 30:106-11. 2006
    ..Confirmation of screened positive samples requires a method that can detect total oxycodone and oxymorphone...
  10. ncbi Clinical pharmacology of 1,4-butanediol and gamma-hydroxybutyrate after oral 1,4-butanediol administration to healthy volunteers
    D Thai
    Amgen Corportion, Thousand Oaks, California, USA
    Clin Pharmacol Ther 81:178-84. 2007
    ..At the modest dose studied, significant clinical effects were not seen...
  11. ncbi Determination of ephedra alkaloid and caffeine concentrations in dietary supplements and biological fluids
    Peyton Jacob
    University of California, San Francisco, Department of Medicine, Division of Clinical Pharmacology, San Francisco General Hospital, 1001 Potrero Avenue, Building 30, 3rd Floor, San Francisco, California 94110, USA
    J Anal Toxicol 28:152-9. 2004
    ..Using this method, low nanogram-per-milliliter concentrations of ephedrine, pseudoephedrine, norephedrine, norpseudoephedrine, methylephedrine, methylpseudoephedrine, and caffeine can be quantitated in a 12-min LC-MS-MS run...
  12. ncbi Hemodynamic effects of ephedra-free weight-loss supplements in humans
    Christine A Haller
    Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine, University of California, San Francisco, 94143, USA
    Am J Med 118:998-1003. 2005
    ..aurantium alone, because an eightfold higher dose of synephrine (Advantra Z) had no effect on blood pressure, but may be attributable to caffeine and other stimulants in the multi-component formulation...
  13. ncbi Mechanistic pharmacokinetic modelling of ephedrine, norephedrine and caffeine in healthy subjects
    C Csajka
    Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143, USA
    Br J Clin Pharmacol 59:335-45. 2005
    ..A saturable process appears to be involved in the metabolism of ephedrine to norephedrine...
  14. ncbi Human pharmacology of a performance-enhancing dietary supplement under resting and exercise conditions
    Christine A Haller
    Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, San Francisco General Hospital, San Francisco, CA, USA
    Br J Clin Pharmacol 65:833-40. 2008
    ..The effect of exercise on the pharmacokinetics and pharmacodynamics of stimulant herbals is unknown...
  15. ncbi Clinical approach to adverse events and interactions related to herbal and dietary supplements
    Christine A Haller
    University of California, San Francisco, California Poison Control System, San Francisco Division, San Francisco, California 94143, USA
    Clin Toxicol (Phila) 44:605-10. 2006
  16. ncbi Incomplete recovery of prescription opioids in urine using enzymatic hydrolysis of glucuronide metabolites
    Ping Wang
    Clinical Laboratories, San Francisco General Hospital, Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California 94110, USA
    J Anal Toxicol 30:570-5. 2006
    ..We conclude that acid hydrolysis is the method of choice for GC-MS confirmation of urine opioids...
  17. ncbi Gamma-hydroxybutyrate and ethanol effects and interactions in humans
    Dung Thai
    Amgen Corporation, Thousand Oaks, CA, USA
    J Clin Psychopharmacol 26:524-9. 2006
    ..Gamma-hydroxybutyrate-plus-ethanol resulted in more adverse effects, including gastrointestinal disturbances, hypotension, and decreased O2sat, but only minimal pharmacokinetic interactions were observed...
  18. ncbi Effect of a multicomponent, ephedra-containing dietary supplement (Metabolife 356) on Holter monitoring and hemostatic parameters in healthy volunteers
    Stephanie F Gardner
    Department of Pharmacy Practice, College of Pharmacy, University of Arkansas for Medical Sciences, 4301 W. Markham #522, Little Rock, AR 72205, USA
    Am J Cardiol 91:1510-3, A9. 2003

Research Grants1

  1. PHARMACOLOGY OF COMBINED EPHEDRINE/CAFFEINE SUPPLEMENTS
    Christine Haller; Fiscal Year: 2004
    ..The long-term objective for the proposed studies is to develop Dr. Haller into an independent career clinical researcher in this field of study. ..