Liancai Mu

Summary

Affiliation: Hackensack University Medical Center
Country: USA

Publications

  1. pmc Parkinson disease affects peripheral sensory nerves in the pharynx
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    J Neuropathol Exp Neurol 72:614-23. 2013
  2. pmc Alpha-synuclein pathology and axonal degeneration of the peripheral motor nerves innervating pharyngeal muscles in Parkinson disease
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, New Jersey 07601, USA
    J Neuropathol Exp Neurol 72:119-29. 2013
  3. pmc Nerve-muscle-endplate band grafting: a new technique for muscle reinnervation
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    Neurosurgery 69:ons208-24; discussion ons224. 2011
  4. pmc Altered pharyngeal muscles in Parkinson disease
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    J Neuropathol Exp Neurol 71:520-30. 2012
  5. pmc Force recovery and axonal regeneration of the sternomastoid muscle reinnervated with the end-to-end nerve anastomosis
    Stanislaw Sobotka
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey, USA
    J Surg Res 182:e51-9. 2013
  6. ncbi request reprint Myosin heavy chain-based fiber types in the adult human cricopharyngeus muscle
    Liancai Mu
    Upper Airway Research Laboratory, Department of Otolaryngology, Mount Sinai School of Medicine, Box 1189, New York, New York 10029, USA
    Muscle Nerve 35:637-48. 2007
  7. pmc Comparison of muscle force after immediate and delayed reinnervation using nerve-muscle-endplate band grafting
    Stanislaw Sobotka
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey, USA
    J Surg Res 179:e117-26. 2013
  8. pmc Locations of the motor endplate band and motoneurons innervating the sternomastoid muscle in the rat
    Xiaolin Zhang
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    Anat Rec (Hoboken) 294:295-304. 2011
  9. pmc Force characteristics of the rat sternomastoid muscle reinnervated with end-to-end nerve repair
    Stanislaw Sobotka
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, 30 Prospect Avenue, Jurist Research Building, Hackensack, NJ 07601, USA
    J Biomed Biotechnol 2011:173471. 2011
  10. pmc The human tongue slows down to speak: muscle fibers of the human tongue
    Ira Sanders
    Alice and David Jurist Institute for Biomedical Research, Hackensack University Medical Center, Hackensack, New Jersey
    Anat Rec (Hoboken) 296:1615-27. 2013

Collaborators

Detail Information

Publications15

  1. pmc Parkinson disease affects peripheral sensory nerves in the pharynx
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    J Neuropathol Exp Neurol 72:614-23. 2013
    ..These abnormalities may decrease pharyngeal sensation, thereby impairing swallowing and airway protective reflexes and contributing to dysphagia and aspiration. ..
  2. pmc Alpha-synuclein pathology and axonal degeneration of the peripheral motor nerves innervating pharyngeal muscles in Parkinson disease
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, New Jersey 07601, USA
    J Neuropathol Exp Neurol 72:119-29. 2013
    ..These findings indicate that motor involvement of the pharynx in PD is one of the factors leading to oropharyngeal dysphagia commonly seen in PD patients...
  3. pmc Nerve-muscle-endplate band grafting: a new technique for muscle reinnervation
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    Neurosurgery 69:ons208-24; discussion ons224. 2011
    ..Because currently existing reinnervation methods result in poor functional recovery, there is a great need to develop new treatment strategies...
  4. pmc Altered pharyngeal muscles in Parkinson disease
    Liancai Mu
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    J Neuropathol Exp Neurol 71:520-30. 2012
    ..The alterations in the pharyngeal muscles may play a pathogenic role in the development of dysphagia in subjects with PD...
  5. pmc Force recovery and axonal regeneration of the sternomastoid muscle reinnervated with the end-to-end nerve anastomosis
    Stanislaw Sobotka
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey, USA
    J Surg Res 182:e51-9. 2013
    ..However, this method generally results in poor functional recovery. This study was designed to determine the correlation of functional recovery to the extent of axonal reinnervation after EEA procedure in a rat model...
  6. ncbi request reprint Myosin heavy chain-based fiber types in the adult human cricopharyngeus muscle
    Liancai Mu
    Upper Airway Research Laboratory, Department of Otolaryngology, Mount Sinai School of Medicine, Box 1189, New York, New York 10029, USA
    Muscle Nerve 35:637-48. 2007
    ..Determination of MHC expression patterns of the CP muscle fibers is critical for evaluating the contractile properties of the sphincter...
  7. pmc Comparison of muscle force after immediate and delayed reinnervation using nerve-muscle-endplate band grafting
    Stanislaw Sobotka
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey, USA
    J Surg Res 179:e117-26. 2013
    ..The graft was obtained from the sternohyoid muscle (donor) and implanted into the ipsilateral paralyzed sternomastoid (SM) muscle (recipient)...
  8. pmc Locations of the motor endplate band and motoneurons innervating the sternomastoid muscle in the rat
    Xiaolin Zhang
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, Hackensack, New Jersey 07601, USA
    Anat Rec (Hoboken) 294:295-304. 2011
    ..These findings are important not only for understanding the neural control of the muscle but also for evaluating the success rate of a given reinnervation procedure when the SM is chosen as a target muscle...
  9. pmc Force characteristics of the rat sternomastoid muscle reinnervated with end-to-end nerve repair
    Stanislaw Sobotka
    Upper Airway Research Laboratory, Department of Research, Hackensack University Medical Center, 30 Prospect Avenue, Jurist Research Building, Hackensack, NJ 07601, USA
    J Biomed Biotechnol 2011:173471. 2011
    ..The SM with delayed nerve repair yielded approximately 40% of the maximal force. Suboptimal recovery of muscle force after EEA demonstrates the importance of developing alternative surgical techniques to treat muscle paralysis...
  10. pmc The human tongue slows down to speak: muscle fibers of the human tongue
    Ira Sanders
    Alice and David Jurist Institute for Biomedical Research, Hackensack University Medical Center, Hackensack, New Jersey
    Anat Rec (Hoboken) 296:1615-27. 2013
    ..Anat Rec, 296:1615-1627, 2013. © 2013 Wiley Periodicals, Inc. ..
  11. doi request reprint The human cricothyroid muscle: three muscle bellies and their innervation patterns
    Liancai Mu
    Upper Airway Research Laboratory, Department of Otolaryngology, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Voice 23:21-8. 2009
    ..The data are also useful for further clarifying the functions of the CT bellies and the ESLN branches and for developing belly-based reinnervation procedures to treat laryngeal paralysis...
  12. doi request reprint Newly revealed cricothyropharyngeus muscle in the human laryngopharynx
    Liancai Mu
    Department of Otolaryngology, Upper Airway Research Laboratory, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    Anat Rec (Hoboken) 291:927-38. 2008
    ..e., slow-tonic, alpha-cardiac, neonatal, and embryonic). In conclusion, the CTP appears to be a newly described and uniquely human muscle with characteristics suggesting a specialized function that may be speech related...
  13. ncbi request reprint Adult human upper esophageal sphincter contains specialized muscle fibers expressing unusual myosin heavy chain isoforms
    Liancai Mu
    Upper Airway Research Laboratory, Department of Otolaryngology, The Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    J Histochem Cytochem 55:199-207. 2007
    ..Identification of the specialized muscle fibers and their distribution patterns in the adult human UES is valuable for a better understanding of the physiological and pathophysiological behaviors of the sphincter...
  14. pmc A three-dimensional atlas of human tongue muscles
    Ira Sanders
    Alice and David Jurist Institute for Biomedical Research, Hackensack University Medical Center, Hackensack, New Jersey, USA
    Anat Rec (Hoboken) 296:1102-14. 2013
    ..The graphics are perhaps the clearest guide to date to aid clinical or basic science investigators in identifying each tongue muscle in any part of the human tongue...
  15. pmc Characteristics of tetanic force produced by the sternomastoid muscle of the rat
    Stanislaw Sobotka
    Department of Research, Upper Airway Research Laboratory, Hackensack University Medical Center, Hackensack, NJ 07601, USA
    J Biomed Biotechnol 2010:194984. 2010
    ....

Research Grants16

  1. ANATOMICAL SPECIALIZATIONS OF THE HUMAN PHARYNX
    Liancai Mu; Fiscal Year: 2010
    ..This research will provide biological basis of neurogenic dysphagia which is critical for the development of novel therapies to treat this disorder. ..
  2. Reinnervation of Paralyzed Muscle by Nerve-Muscle-Endplate Band Grafting
    Liancai Mu; Fiscal Year: 2010
    ..Our preliminary work showed that this technique results in better outcomes than currently used methods. The data obtained from this research is useful for future clinical application to treat muscle paralysis. ..
  3. ANATOMICAL SPECIALIZATIONS OF THE HUMAN PHARYNX
    Liancai Mu; Fiscal Year: 2007
    ..The data may help to guide treatment strategies that are aimed at using implantable pharyngeal muscle nerve stimulators to alleviate dysphagia and airway obstruction during sleep. ..
  4. ANATOMICAL SPECIALIZATIONS OF THE HUMAN PHARYNX
    Liancai Mu; Fiscal Year: 2004
    ....
  5. Reinnervation of Paralyzed Muscle by Nerve-Muscle-Endplate Band Grafting
    Liancai Mu; Fiscal Year: 2011
    ..Our preliminary work showed that this technique results in better outcomes than currently used methods. The data obtained from this research is useful for future clinical application to treat muscle paralysis. ..