Affiliation: H. Lee Moffitt Cancer Center and Research Institute
- Patient-reported outcomes and the evolution of adverse event reporting in oncologyAndy Trotti
Division of Radiation Oncology, H Lee Moffitt Cancer Center at University of South Florida, Tampa, FL 33612 9416, USA
J Clin Oncol 25:5121-7. 2007..Therefore, care must be used when developing health outcomes and safety data collection plans...
- TAME: development of a new method for summarising adverse events of cancer treatment by the Radiation Therapy Oncology GroupAndy Trotti
H Lee Moffitt Cancer Center at the University of South Florida, Tampa, FL 33612 9497, USA
Lancet Oncol 8:613-24. 2007....
- A multinational, randomized phase III trial of iseganan HCl oral solution for reducing the severity of oral mucositis in patients receiving radiotherapy for head-and-neck malignancyAndy Trotti
Radiation Oncology Program, H Lee Moffitt Cancer Center at the University of South Florida, Tampa, FL, USA
Int J Radiat Oncol Biol Phys 58:674-81. 2004..It is hypothesized that infection plays a role in the development of OM. We tested the efficacy of iseganan HCl (iseganan), a synthetic peptide with broad-spectrum antimicrobial activity, for preventing RT-associated OM...
- Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature reviewAndy Trotti
Radiation Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
Radiother Oncol 66:253-62. 2003..While it appears that mucositis may lead to hospitalization and treatment interruptions, its overall impact on outcomes has not been adequately investigated...
- CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatmentAndy Trotti
H Lee Moffitt Cancer Center at the University of South Florida, Tampa, FL 33612, USA
Semin Radiat Oncol 13:176-81. 2003..This article updates recent progress in the evolution of adverse effects grading systems and reviews the development of CTCAE v3.0...
- Outcomes of postoperative concurrent chemoradiotherapy for locally advanced major salivary gland carcinomaTawee Tanvetyanon
Head and Neck Program, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
Arch Otolaryngol Head Neck Surg 135:687-92. 2009..To investigate the potential value of postoperative concurrent chemoradiation among patients with high-risk salivary gland carcinomas...
- Assessment of toxicity in cooperative oncology clinical trials: the long and short of itClement K Gwede
Dept. of Interdisciplinary Oncology, University of South Florida and H. Lee Moffitt Cancer Center and Research Institute, Tampa, USA
J Oncol Manag 11:15-21. 2002..The potential implications for toxicity data management practices, data quality, patient care management and resource utilization are discussed...
- Survival outcomes of squamous cell carcinoma arising from sinonasal inverted papilloma: report of 6 cases with systematic review and pooled analysisTawee Tanvetyanon
Head and Neck Program, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA
Am J Otolaryngol 30:38-43. 2009..Squamous cell carcinoma (SCC) is associated with IP in about 7% of cases. To date, there has been no pooled analysis to formulate a survival outcome associated with this rare condition...
- The evolution and application of toxicity criteriaAndy Trotti
H. Lee Moffitt Cancer Center at the University of South Florida, Tampa, FL 33612-9497, USA
Semin Radiat Oncol 12:1-3. 2002..Just as the revised CTC has provided a new common standard for the grading of acute effects, a similar effort is needed in the late effects area. The creation of a unified late effects system is under active development...
- The need for adverse effects reporting standards in oncology clinical trialsAndy Trotti
J Clin Oncol 22:19-22. 2004
- Complications of radiation therapy for head and neck cancers. The patient's perspectiveAlison M Rose-Ped
Empirica, Inc, Portland, Ore 97225, USA
Cancer Nurs 25:461-7; quiz 468-9. 2002..Trends toward more aggressive management of head and neck cancers underscore the need for new and effective therapies for oropharyngeal mucositis occurring in patients receiving radiotherapy...
- Evaluation of new treatments in radiation oncology: are they better than standard treatments?Heloisa P Soares
H Lee Moffitt Cancer Center and Research Institute at University of South Florida, Tampa 33612, USA
JAMA 293:970-8. 2005..To describe accurately the outcomes of innovations that are tested in randomized controlled trials (RCTs) 3 factors have to be considered: publication rate, quality of trials, and the choice of the adequate comparator intervention...
- Concomitant boost radiation plus concurrent cisplatin for advanced head and neck carcinomas: radiation therapy oncology group phase II trial 99-14K Kian Ang
The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 97, Houston, TX 77030, USA
J Clin Oncol 23:3008-15. 2005..To investigate the feasibility of combining concomitant boost accelerated radiation regimen (AFX-C) with cisplatin and to assess its toxicity and the relapse pattern and survival in patients with advanced head and neck carcinoma (HNC)...
- Adverse event reporting and developments in radiation biology after normal tissue injury: International Atomic Energy Agency consultationYuhchyau Chen
Department of Radiation Oncology, James P Wilmot Cancer Center, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 8647, USA
Int J Radiat Oncol Biol Phys 64:1442-51. 2006....
- Measurement of quality of life in head and neck cancer patients utilizing the quality of life radiation therapy questionnaireMonika Janda
Department of Radiotherapy and Radiobiology, University Hospital Medical School of Vienna, Austria
Strahlenther Onkol 178:153-8. 2002..The H&N module is useful for patients undergoing treatment for head and neck cancer...