T A Sellers

Summary

Affiliation: H. Lee Moffitt Cancer Center and Research Institute
Country: USA

Publications

  1. pmc No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Breast Cancer Res 14:R7. 2012
  2. pmc Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development
    Abra G Brisbin
    Department of Health Sciences Research, Mayo Clinic, Rochester, USA
    BMC Med Genet 12:156. 2011
  3. doi request reprint New lung cancer susceptibility locus identified: significance and implications for other genome-wide association studies
    Thomas A Sellers
    Department of Cancer Epidemiology, Biostatics Core, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Cancer Discov 2:110-1. 2012
  4. pmc Linkage analysis of obesity phenotypes in pre- and post-menopausal women from a United States mid-western population
    Linda E Kelemen
    Department of Population Health Research, Alberta Health Services Cancer Care, Calgary, AB, Canada
    BMC Med Genet 11:156. 2010
  5. pmc Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer
    Kristin L White
    Mayo Clinic College of Medicine, Rochester, MN, USA
    BMC Cancer 9:170. 2009
  6. pmc Unpasteurized milk consumption and subsequent risk of cancer
    Thomas A Sellers
    H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Cancer Causes Control 19:805-11. 2008
  7. ncbi request reprint Association of childhood and adolescent anthropometric factors, physical activity, and diet with adult mammographic breast density
    T A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer and Research Institute, Tampa, FL 33612, USA
    Am J Epidemiol 166:456-64. 2007
  8. ncbi request reprint Association of diabetes with mammographic breast density and breast cancer in the Minnesota breast cancer family study
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Cancer Causes Control 18:505-15. 2007
  9. ncbi request reprint Deletion polymorphism of UDP-glucuronosyltransferase 2B17 and risk of prostate cancer in African American and Caucasian men
    Jong Park
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Cancer Epidemiol Biomarkers Prev 15:1473-8. 2006
  10. pmc Association of single nucleotide polymorphisms in glycosylation genes with risk of epithelial ovarian cancer
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Cancer Epidemiol Biomarkers Prev 17:397-404. 2008

Research Grants

Detail Information

Publications79

  1. pmc No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Breast Cancer Res 14:R7. 2012
    ....
  2. pmc Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development
    Abra G Brisbin
    Department of Health Sciences Research, Mayo Clinic, Rochester, USA
    BMC Med Genet 12:156. 2011
    ..However, the abundance of associations around 128 Mb on chromosome 8 could mask the appearance of a weaker, but important, association elsewhere on 8q24...
  3. doi request reprint New lung cancer susceptibility locus identified: significance and implications for other genome-wide association studies
    Thomas A Sellers
    Department of Cancer Epidemiology, Biostatics Core, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Cancer Discov 2:110-1. 2012
    ..This work is important not only for its potential implications on control of this dreaded malignancy but also for its methodologic contributions that can advance the field of molecular-genetic epidemiology...
  4. pmc Linkage analysis of obesity phenotypes in pre- and post-menopausal women from a United States mid-western population
    Linda E Kelemen
    Department of Population Health Research, Alberta Health Services Cancer Care, Calgary, AB, Canada
    BMC Med Genet 11:156. 2010
    ..Women are also more likely to distribute weight in the abdomen following menopause. We investigated whether genetic loci link with obesity-related phenotypes differently by menopausal status...
  5. pmc Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer
    Kristin L White
    Mayo Clinic College of Medicine, Rochester, MN, USA
    BMC Cancer 9:170. 2009
    ..Inhibitors of kappaB (IkappaB) prevent NF-kappaB activation by sequestering NF-kappaB proteins in the cytoplasm until IkappaB proteins are phosphorylated and degraded...
  6. pmc Unpasteurized milk consumption and subsequent risk of cancer
    Thomas A Sellers
    H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Cancer Causes Control 19:805-11. 2008
    ..92, 95% CI: 0.83-1.02 for consumption only as a child, and RR = 0.91; 95% CI: 0.79-1.04 for consumption as a child and an adult). These data suggest that consumption of unpasteurized milk does not increase risk of cancer...
  7. ncbi request reprint Association of childhood and adolescent anthropometric factors, physical activity, and diet with adult mammographic breast density
    T A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer and Research Institute, Tampa, FL 33612, USA
    Am J Epidemiol 166:456-64. 2007
    ..Adolescent physical activity and diet were unrelated to percent density. These results suggest that adolescent height, a known risk factor for breast cancer, is also associated with mammographic percent density...
  8. ncbi request reprint Association of diabetes with mammographic breast density and breast cancer in the Minnesota breast cancer family study
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Cancer Causes Control 18:505-15. 2007
    ..Our findings suggest that breast cancer risk may be increased among women with type II diabetes, but that type II diabetes does not significantly influence mammographic breast density...
  9. ncbi request reprint Deletion polymorphism of UDP-glucuronosyltransferase 2B17 and risk of prostate cancer in African American and Caucasian men
    Jong Park
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Cancer Epidemiol Biomarkers Prev 15:1473-8. 2006
    ..The purpose of this study was to determine if the deletion polymorphism is associated with susceptibility to prostate cancer...
  10. pmc Association of single nucleotide polymorphisms in glycosylation genes with risk of epithelial ovarian cancer
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Cancer Epidemiol Biomarkers Prev 17:397-404. 2008
    ..10 frequency; odds ratio, 0.07; P = 0.01) compared with the most common haplotype (0.39 frequency). These results suggest that genetic polymorphisms in the glycoslyation process may be novel risk factors for ovarian cancer...
  11. pmc A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer
    Tuya Pal
    Department of Cancer Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Cancer 113:733-42. 2008
    ..The ability to make such distinctions may be of diagnostic, prognostic, and therapeutic utility...
  12. pmc Population-based case-control study of diabetes and breast cancer risk in Hispanic and non-Hispanic White women living in US southwestern states
    Dana E Rollison
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Am J Epidemiol 167:447-56. 2008
    ..54, 95% confidence interval: 0.37, 0.79). In this study, diabetes was not associated with breast cancer overall, although the inverse association with gestational diabetes warrants further investigation...
  13. pmc Proteomic contributions to personalized cancer care
    John M Koomen
    H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, Florida 33612, USA
    Mol Cell Proteomics 7:1780-94. 2008
    ....
  14. ncbi request reprint Association between polymorphisms in HSD3B1 and UGT2B17 and prostate cancer risk
    Jong Y Park
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Urology 70:374-9. 2007
    ..The purpose of this study was to determine whether polymorphisms in HSD3B1 and UGT2B17 increase the risk of prostate cancer...
  15. pmc Systematic review and meta-analysis of ovarian cancers: estimation of microsatellite-high frequency and characterization of mismatch repair deficient tumor histology
    Tuya Pal
    H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Clin Cancer Res 14:6847-54. 2008
    ....
  16. pmc Familial and perceived risk of breast cancer in relation to use of complementary medicine
    Cynthia D Myers
    H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, MRC PSY, Tampa, FL 33617, USA
    Cancer Epidemiol Biomarkers Prev 17:1527-34. 2008
    ..To examine the use of complementary and alternative medicine (CAM) by women with varying levels of familial and perceived risk of breast cancer with the goal of preventing breast cancer...
  17. pmc Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium
    Catherine M Phelan
    Department of Epidemiology and Genetics, Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Epidemiol Biomarkers Prev 19:600-4. 2010
    ..03). This study underscores the need for replication of putative findings in genetic association studies...
  18. ncbi request reprint Modes of delivery of genetic testing services and the uptake of cancer risk management strategies in BRCA1 and BRCA2 carriers
    T Pal
    Division of Population Sciences, H Lee Moffitt Cancer Center, Tampa, FL, USA
    Clin Genet 85:49-53. 2014
    ..Identification of factors to optimize delivery of these specialized GC services is important to maximize implementation of CRM strategies in BRCA carriers. ..
  19. pmc An automated approach for estimation of breast density
    John J Heine
    H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Cancer Epidemiol Biomarkers Prev 17:3090-7. 2008
    ..The automated breast density method is a viable option for quantitatively assessing breast density from digitized film mammograms...
  20. ncbi request reprint Association between polymorphisms in the DNA repair genes XRCC1 and APE1, and the risk of prostate cancer in white and black Americans
    Lan Chen
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center, Tampa, Florida, USA
    J Urol 175:108-12; discussion 112. 2006
    ..XRCC1 and APE1 are enzymes involved in the repair of DNA strand breaks and base damage that arise from various endogenous and exogenous oxidants. We determined whether polymorphisms in XRCC1 and APE1 increase the risk of prostate cancer...
  21. pmc Breast Imaging Reporting and Data System (BI-RADS) breast composition descriptors: automated measurement development for full field digital mammography
    E E Fowler
    Department of Cancer Epidemiology, Division of Population Sciences, H Lee Moffitt Cancer Center, Tampa, Florida 33612
    Med Phys 40:113502. 2013
    ..New techniques are presented and evaluated for generating automated BI-RADS breast composition descriptors using both raw and calibrated full field digital mammography (FFDM) image data...
  22. ncbi request reprint Examining population stratification via individual ancestry estimates versus self-reported race
    Jill S Barnholtz-Sloan
    Cancer Prevention and Control Program, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA
    Cancer Epidemiol Biomarkers Prev 14:1545-51. 2005
    ..This study suggests that significant population substructure differences exist that self-reported race alone does not capture and that individual ancestry may be confounded with disease status and/or a candidate gene risk genotype...
  23. ncbi request reprint Estrogen bioactivation, genetic polymorphisms, and ovarian cancer
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33602, USA
    Cancer Epidemiol Biomarkers Prev 14:2536-43. 2005
    ..015). Although preliminary, this study provides some support for the hypothesis that low-penetrance susceptibility alleles may influence risk of epithelial ovarian cancer...
  24. pmc Single nucleotide polymorphisms in DNA repair genes and prostate cancer risk
    Jong Y Park
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Methods Mol Biol 471:361-85. 2009
    ..This report reviews the published epidemiologic literature on the association of SNPs in genes involved in DNA repair pathways and prostate cancer risk...
  25. pmc Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer
    W Kong
    Department of Molecular Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Oncogene 33:679-89. 2014
    ....
  26. pmc Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk
    Jennifer Permuth-Wey
    Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida 33612 9416, USA
    Cancer Epidemiol Biomarkers Prev 20:1131-45. 2011
    ..Mitochondria contribute to oxidative stress, a phenomenon implicated in ovarian carcinogenesis. We hypothesized that inherited variants in mitochondrial-related genes influence epithelial ovarian cancer (EOC) susceptibility...
  27. ncbi request reprint Opportunities and barriers in the age of team science: strategies for success
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Causes Control 17:229-37. 2006
    ..To provide the voice of experience to investigators contemplating engagement in the realm of "team science"...
  28. doi request reprint Epidemiology of ovarian cancer
    Jennifer Permuth-Wey
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Methods Mol Biol 472:413-37. 2009
    ..Many of the causes of ovarian cancer are yet to be identified. Additional research is needed to better understand the etiology of this deadly disease...
  29. ncbi request reprint Longitudinal trends in mammographic percent density and breast cancer risk
    Celine M Vachon
    Mayo Clinic College of Medicine, Charlton 6 239, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:921-8. 2007
    ..Mammographic density is a strong risk factor for breast cancer. However, whether changes in mammographic density are associated with risk remains unclear...
  30. ncbi request reprint Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer
    Simon A Gayther
    Translational Research Laboratories, University College London, London, United Kingdom
    Cancer Res 67:3027-35. 2007
    ..This study highlights the need for multicenter collaborations for genetic association studies...
  31. ncbi request reprint A comprehensive examination of CYP19 variation and breast density
    Janet E Olson
    Division of Epidemiology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55901, USA
    Cancer Epidemiol Biomarkers Prev 16:623-5. 2007
  32. pmc Genetic variation in the one-carbon transfer pathway and ovarian cancer risk
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Res 68:2498-506. 2008
    ..Interventions with modifiable factors such as multivitamin intake may reduce risk...
  33. ncbi request reprint Stratification of breast cancer risk in women with atypia: a Mayo cohort study
    Amy C Degnim
    Division of General Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Clin Oncol 25:2671-7. 2007
    ..Atypical hyperplasia is a well-recognized risk factor for breast cancer, conveying an approximately four-fold increased risk. Data regarding long-term absolute risk and factors for risk stratification are needed...
  34. pmc AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study
    Fergus J Couch
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:1416-21. 2007
    ..In summary, the F31I polymorphism in AURKA is not associated with a modified risk of breast cancer in BRCA1 and BRCA2 carriers...
  35. ncbi request reprint Strong evidence of a genetic determinant for mammographic density, a major risk factor for breast cancer
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Res 67:8412-8. 2007
    ..4 cM). The putative locus on chromosome 5p is likely to account for up to 22% of variation in MD. Hence, 1 or more of the 45 candidate genes in this region could explain a large proportion of MD and, potentially, breast cancer...
  36. pmc Can genes for mammographic density inform cancer aetiology?
    Linda E Kelemen
    Department of Population Health Research, Alberta Cancer Board, 1, 331 29th Street North West, Calgary, Alberta T2N 4N2, Canada
    Nat Rev Cancer 8:812-23. 2008
    ..In this Perspective, we review the limited genetic studies of MD and propose future directions...
  37. pmc Factors associated with breast cancer prevention communication between mothers and daughters
    Pamela S Sinicrope
    Behavioral Health Program, Mayo Clinic Rochester College of Medicine, Rochester, Minnesota 55905, USA
    J Womens Health (Larchmt) 17:1017-23. 2008
    ..We examined the degree to which mothers reported providing advice on breast cancer prevention to their daughters, the content of such advice, and correlates of providing such advice...
  38. pmc Mammographic density, breast cancer risk and risk prediction
    Celine M Vachon
    Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Breast Cancer Res 9:217. 2007
    ..Promising new measures of mammographic density, including volumetric density, which can be standardized using full-field digital mammography, will likely result in a stronger risk factor and improve accuracy of risk prediction models...
  39. pmc Association of mammographic density with the pathology of subsequent breast cancer among postmenopausal women
    Karthik Ghosh
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:872-9. 2008
    ..Limited studies have examined the associations between mammographic density and subsequent breast tumor characteristics...
  40. doi request reprint Dietary patterns and breast density in the Minnesota Breast Cancer Family Study
    Marilyn Tseng
    Division of Population Science, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, 19111, USA
    Cancer Causes Control 19:481-9. 2008
    ..Whether dietary patterns, rather than single foods or nutrients, are associated with breast density is not known. We investigated this in the Minnesota Breast Cancer Family Study...
  41. ncbi request reprint Age-specific trends in mammographic density: the Minnesota Breast Cancer Family Study
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Am J Epidemiol 167:1027-36. 2008
    ..These data suggest that menopause, baseline PD, postmenopausal hormone use, and body mass index predict changes in mammographic density trends during adult life...
  42. ncbi request reprint Mammographic breast density as a general marker of breast cancer risk
    Celine M Vachon
    Mayo Clinic College of Medicine, Charlton 6 239, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:43-9. 2007
    ..Overall mammographic density seems to represent a general marker of breast cancer risk that is not specific to breast side or location of the eventual cancer...
  43. ncbi request reprint Mammographic density of the breast
    Celine M Vachon
    N Engl J Med 348:174-5; author reply 174-5. 2003
  44. ncbi request reprint Prenatal and perinatal correlates of adult mammographic breast density
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 14:1502-8. 2005
    ..We examined the hypothesis that those factors associated with higher levels of estrogen during pregnancy or shortly after birth are associated with higher mammographic breast density in adulthood...
  45. ncbi request reprint Anthropometric characteristics, physical activity, and risk of non-Hodgkin's lymphoma subtypes and B-cell chronic lymphocytic leukemia: a prospective study
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Am J Epidemiol 156:527-35. 2002
    ..The opposite associations of body mass index with small lymphocytic lymphoma versus B-CLL may be a chance finding but, if confirmed, would suggest different etiologies for these malignancies...
  46. ncbi request reprint Association of gain and loss of weight before and after menopause with risk of postmenopausal breast cancer in the Iowa women's health study
    Michelle Harvie
    Univeristy Department of Medical Oncology, Christie Hospital, Manchester, United Kingdom
    Cancer Epidemiol Biomarkers Prev 14:656-61. 2005
    ..These data suggest prevention of weight gain between age 18 years and menopause or weight loss and maintenance during these years reduces risk of postmenopausal breast cancer...
  47. ncbi request reprint Case-control study of increased mammographic breast density response to hormone replacement therapy
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic Cancer Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1382-8. 2002
    ..Because all risk factors examined accounted for only 26% of the variation in the HRT response, genes or other unmeasured factors are thought to be involved...
  48. ncbi request reprint Bilateral oophorectomy and breast cancer risk reduction among women with a family history
    Janet E Olson
    Health Science Research, Mayo Foundation, Rochester, MN 55905, USA
    Cancer Detect Prev 28:357-60. 2004
    ..We investigated whether removal of the ovaries is an appropriate risk reduction option for women at elevated risk of breast cancer based on family history of breast cancer...
  49. ncbi request reprint Pathologic characteristics of breast parenchyma in patients with hereditary breast carcinoma, including BRCA1 and BRCA2 mutation carriers
    Camilo Adem
    Division of Laboratory Genetics, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Cancer 97:1-11. 2003
    ....
  50. ncbi request reprint Review of proteomics with applications to genetic epidemiology
    Thomas A Sellers
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Genet Epidemiol 24:83-98. 2003
    ..Several examples are presented to illustrate the potential application of proteomics to the field of genetic epidemiology, and we conclude with various considerations regarding design and analysis...
  51. ncbi request reprint Evaluation of familial clustering of breast and prostate cancer in the Minnesota Breast Cancer Family Study
    Dawn M Grabrick
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Detect Prev 27:30-6. 2003
    ..8, 95% C.I.: 0.5-1.2). These results provide little evidence that male relatives in high-risk breast cancer families are at increased risk of prostate cancer...
  52. ncbi request reprint Reoperations after prophylactic mastectomy with or without implant reconstruction
    Sara M Zion
    New York Presbyterian Hospital, Weill Cornell Medical Center, New York, New York, USA
    Cancer 98:2152-60. 2003
    ..The authors characterized the unanticipated reoperations after prophylactic mastectomy, with or without implant reconstruction...
  53. ncbi request reprint Benign breast disease and the risk of breast cancer
    Lynn C Hartmann
    Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    N Engl J Med 353:229-37. 2005
    ..Benign breast disease is an important risk factor for breast cancer. We studied a large group of women with benign breast disease to obtain reliable estimates of this risk...
  54. ncbi request reprint High-folate diets and breast cancer survival in a prospective cohort study
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Nutr Cancer 44:139-44. 2002
    ..These findings, although preliminary, afford some reassurance that folate supplementation is unlikely to have a significant adverse effect on survival after chemotherapy for breast cancer...
  55. ncbi request reprint Postmenopausal cancer risk after self-reported endometriosis diagnosis in the Iowa Women's Health Study
    Janet E Olson
    Mayo Foundation, Health Sciences Research, Rochester, Minnesota 55905, USA
    Cancer 94:1612-8. 2002
    ..A recent study reported that women with a hospital discharge diagnosis of endometriosis were at increased risk of cancer at any site, breast cancer, ovarian cancer, and hematopoietic malignancies, especially non-Hodgkin lymphoma (NHL)...
  56. ncbi request reprint Methylenetetrahydrofolate reductase haplotype tag single-nucleotide polymorphisms and risk of breast cancer
    Yvette N Martin
    Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 15:2322-4. 2006
  57. ncbi request reprint Preventive health behaviors and familial breast cancer
    Lisa Madlensky
    University of California San Diego Cancer Center, 9500 Gilman Drive, La Jolla, CA 92093 0901, USA
    Cancer Epidemiol Biomarkers Prev 14:2340-5. 2005
    ..To examine medical and lifestyle preventive behaviors among women with varying levels of familial breast cancer risk...
  58. ncbi request reprint Age-related lobular involution and risk of breast cancer
    Tia R Milanese
    Mayo Medical School, Rochester, MN 55905, USA
    J Natl Cancer Inst 98:1600-7. 2006
    ..As women age, the lobules in their breasts undergo involution or regression. We investigated whether lobular involution in women with benign breast disease was associated with subsequent breast cancer risk...
  59. ncbi request reprint Prepregnancy exposure to cigarette smoking and subsequent risk of postmenopausal breast cancer
    Janet E Olson
    Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1423-8. 2005
    ..To examine the association of cigarette smoking before first pregnancy with risk of postmenopausal breast cancer in a large population-based cohort...
  60. ncbi request reprint Clinically confirmed type 2 diabetes mellitus and colorectal cancer risk: a population-based, retrospective cohort study
    Paul J Limburg
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Gastroenterol 101:1872-9. 2006
    ..However, existing data are inconsistent. We investigated CRC risks, overall and by anatomic subsite, within a population-based inception cohort of clinically confirmed type 2 DM subjects...
  61. ncbi request reprint No association between 25-hydroxyvitamin D and mammographic density
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 5th Floor, 60 Murray Street, Toronto, Ontario, Canada M5G 1X5
    Cancer Epidemiol Biomarkers Prev 15:1988-92. 2006
    ..Unlike some previous reports, vitamin D does not seem to be related to mammographic density in this cohort...
  62. pmc A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches
    Janet E Olson
    Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, MN 55901, USA
    Breast Cancer Res Treat 102:237-47. 2007
    ..We recently published resequencing data on 88 polymorphisms identified in that gene. The hypothesis tested in this study was that polymorphisms, or haplotypes, in CYP19 are related to risk of breast cancer...
  63. ncbi request reprint Association of parity and ovarian cancer risk by family history of breast or ovarian cancer in a population-based study of postmenopausal women
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Epidemiology 13:66-71. 2002
    ..Nulliparity may be more strongly associated with an increased risk of ovarian cancer among women with a family history of breast or ovarian cancer, compared with women who do not have a family history of those cancers...
  64. ncbi request reprint Hormone replacement therapy and risk of non-hodgkin lymphoma and chronic lymphocytic leukemia
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1466-71. 2002
    ..For diffuse NHL, 64% of the cases were nodal, and there was no association of HRT with either nodal or extra-nodal sites. These data suggest that HRT is a risk factor for follicular NHL but not for diffuse or small lymphocyte NHL or CLL...
  65. ncbi request reprint Interaction of dietary folate intake, alcohol, and risk of hormone receptor-defined breast cancer in a prospective study of postmenopausal women
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1104-7. 2002
    ....
  66. ncbi request reprint Outcomes of training nurses to conduct breast and cervical cancer screening of Native American women
    Wesley O Petersen
    Department of Health Sciences Research, Mayo Clinic Comprehensive Cancer Center, Rochester, Minnesota, USA
    Holist Nurs Pract 16:58-79. 2002
    ..Findings show that Native WEB training is associated with increased screening activity at all three levels...
  67. ncbi request reprint Evaluation of a program to train nurses to screen for breast and cervical cancer among Native American women
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic Cancer Center, Rochester, Minnesota 55905, USA
    J Cancer Educ 17:24-7. 2002
    ....
  68. ncbi request reprint Interaction of adolescent anthropometric characteristics and family history on breast cancer risk in a Historical Cohort Study of 426 families (USA)
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Causes Control 15:1-9. 2004
    ..To determine whether the association of adolescent anthropometric characteristics with breast cancer is modified by a family history of the disease...
  69. ncbi request reprint Satisfaction after contralateral prophylactic mastectomy: the significance of mastectomy type, reconstructive complications, and body appearance
    Marlene H Frost
    Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 23:7849-56. 2005
    ..The purpose of this research is to evaluate women's long-term satisfaction with CPM, factors influencing satisfaction, and psychological and social function after CPM...
  70. ncbi request reprint Multivitamin and alcohol intake and folate receptor alpha expression in ovarian cancer
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 14:2168-72. 2005
    ..The association of multivitamin intake with ovarian cancer may depend on FRalpha expression level...
  71. ncbi request reprint Breast biopsy utilization: a population-based study
    Karthik Ghosh
    Division of General Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Arch Intern Med 165:1593-8. 2005
    ..However, scant data exist regarding the utilization of breast biopsies in the community population...
  72. ncbi request reprint Association of folate and alcohol with risk of ovarian cancer in a prospective study of postmenopausal women
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Causes Control 15:1085-93. 2004
    ..These findings suggest that alcohol consumption is inversely related to postmenopausal ovarian cancer, and that the association of folate with ovarian cancer may vary by the amount of alcohol consumed...
  73. ncbi request reprint Evaluation of a training program to prepare community health representatives to promote breast and cervix cancer screening among native american women
    Wesley O Petersen
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Cancer Educ 19:237-43. 2004
    ..focus of training? and (2) Does training empower CHRs and, indirectly, their facilities to educate about breast and cervix cancer, promote screening, and teach breast self-exam skills to American Indian and Alaska Native women?..
  74. ncbi request reprint Genetic variation and cancer: improving the environment for publication of association studies
    Timothy R Rebbeck
    Cancer Epidemiol Biomarkers Prev 13:1985-6. 2004
  75. ncbi request reprint ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers
    Camilo Adem
    Division of Laboratory Genetics, Mayo Clinic and Foundation, Rochester, Minnesota, USA
    Genes Chromosomes Cancer 41:1-11. 2004
    ....
  76. ncbi request reprint Genetic ancestry and molecular epidemiology
    Thomas A Sellers
    Cancer Epidemiol Biomarkers Prev 13:499-500. 2004
  77. ncbi request reprint Cigarette smoking and colorectal cancer: long-term, subsite-specific risks in a cohort study of postmenopausal women
    Paul J Limburg
    Divisions of Gastroenterology and Hepatology and Epidemiology, Mayo Clinic Cancer Center, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 1:202-10. 2003
    ..However, long-term CRC risk estimates among female smokers remain limited and inconsistent. The goal of this prospective study was to assess cigarette smoking and CRC risk, overall and by anatomic subsite, among postmenopausal women...
  78. ncbi request reprint Does folate intake decrease risk of postmenopausal breast cancer among women with a family history?
    Thomas A Sellers
    Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Cancer Causes Control 15:113-20. 2004
    ..We examined whether the putative benefit extends to women with a family history (FH) of breast cancer using a cohort of 33,552 postmenopausal women aged 55-69 years in 1986...
  79. ncbi request reprint Recreational physical activity and risk of postmenopausal breast cancer based on hormone receptor status
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Arch Intern Med 166:2478-83. 2006
    ..The objective of this study was to examine the association of physical activity with breast cancer incidence based on ER/PR status of the tumor...

Research Grants8

  1. Estrogen Bioactivation and Risk of Ovarian Cancer
    Thomas Sellers; Fiscal Year: 2002
    ..It is innovative, plausible, and important to evaluate similar associations with epithelial ovarian cancer. The results could have profound implications for our understanding of the disease. ..
  2. Estrogen Bioactivation and Risk of Ovarian Cancer
    Thomas Sellers; Fiscal Year: 2003
    ..It is innovative, plausible, and important to evaluate similar associations with epithelial ovarian cancer. The results could have profound implications for our understanding of the disease. ..
  3. Estrogen Bioactivation and Risk of Ovarian Cancer
    Thomas Sellers; Fiscal Year: 2004
    ..It is innovative, plausible, and important to evaluate similar associations with epithelial ovarian cancer. The results could have profound implications for our understanding of the disease. ..
  4. Estrogen Bioactivation and Risk of Ovarian Cancer
    Thomas Sellers; Fiscal Year: 2005
    ..It is innovative, plausible, and important to evaluate similar associations with epithelial ovarian cancer. The results could have profound implications for our understanding of the disease. ..
  5. Haplotype-Based Genome Screen for Ovarian Cancer Loci
    Thomas Sellers; Fiscal Year: 2008
    ..Success in this endeavor will not only allow identification of women at risk for ovarian cancer, but will elucidate genes involved in the pathogenesis of this deadly malignancy. ..
  6. Haplotype-Based Genome Screen for Ovarian Cancer Loci
    Thomas Sellers; Fiscal Year: 2009
    ..Success in this endeavor will not only allow identification of women at risk for ovarian cancer, but will elucidate genes involved in the pathogenesis of this deadly malignancy. ..
  7. Haplotype-Based Genome Screen for Ovarian Cancer Loci
    Thomas A Sellers; Fiscal Year: 2010
    ..Success in this endeavor will not only allow identification of women at risk for ovarian cancer, but will elucidate genes involved in the pathogenesis of this deadly malignancy. ..
  8. Haplotype-Based Genome Screen for Ovarian Cancer Loci
    Thomas Sellers; Fiscal Year: 2009
    ..Success in this endeavor will not only allow identification of women at risk for ovarian cancer, but will elucidate genes involved in the pathogenesis of this deadly malignancy. ..