Tuya Pal

Summary

Affiliation: H. Lee Moffitt Cancer Center and Research Institute
Country: USA

Publications

  1. doi request reprint Interest of individuals from BRCA families to participate in research studies focused on male BRCA carriers
    Tuya Pal
    H Lee Moffitt Cancer Center, Tampa, FL, USA
    Fam Cancer 12:615-9. 2013
  2. pmc A statewide survey of practitioners to assess knowledge and clinical practices regarding hereditary breast and ovarian cancer
    Tuya Pal
    Moffitt Cancer Center, 12902 Magnolia Drive MRC CANCONT, Tampa, FL 33612, USA
    Genet Test Mol Biomarkers 17:367-75. 2013
  3. doi request reprint Early onset breast cancer in a registry-based sample of African-american women: BRCA mutation prevalence, and other personal and system-level clinical characteristics
    Tuya Pal
    Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Breast J 19:189-92. 2013
  4. pmc Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer
    T Pal
    Departments of Cancer Epidemiology, Biostatistics, Anatomic Pathology and Experimental Therapeutics, Moffitt Cancer Center, MRC CANCONT, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Br J Cancer 107:1783-90. 2012
  5. ncbi request reprint Genetic risk assessments in individuals at high risk for inherited breast cancer in the breast oncology care setting
    Tuya Pal
    Population Sciences Department of Cancer Epidemiology, Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Control 19:255-66. 2012
  6. doi request reprint Recruitment of black women for a study of inherited breast cancer using a cancer registry-based approach
    Tuya Pal
    Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Genet Test Mol Biomarkers 15:69-77. 2011
  7. pmc Systematic review and meta-analysis of ovarian cancers: estimation of microsatellite-high frequency and characterization of mismatch repair deficient tumor histology
    Tuya Pal
    H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Clin Cancer Res 14:6847-54. 2008
  8. doi request reprint BRCA1/2 in high-risk African American women with breast cancer: providing genetic testing through various recruitment strategies
    Tuya Pal
    H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Genet Test 12:401-7. 2008
  9. pmc A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer
    Tuya Pal
    Department of Cancer Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Cancer 113:733-42. 2008
  10. ncbi request reprint The presence of germ line mosaicism in cleidocranial dysplasia
    T Pal
    Department of Pediatrics, All Children s Hospital, College of Medicine, The University of South Florida, St Petersburg, Florida 33612, USA
    Clin Genet 71:589-91. 2007

Research Grants

Detail Information

Publications28

  1. doi request reprint Interest of individuals from BRCA families to participate in research studies focused on male BRCA carriers
    Tuya Pal
    H Lee Moffitt Cancer Center, Tampa, FL, USA
    Fam Cancer 12:615-9. 2013
    ..The importance of further studying this topic is underscored by emerging literature that suggest cancer surveillance and treatment decisions may improve outcomes in men with BRCA mutations...
  2. pmc A statewide survey of practitioners to assess knowledge and clinical practices regarding hereditary breast and ovarian cancer
    Tuya Pal
    Moffitt Cancer Center, 12902 Magnolia Drive MRC CANCONT, Tampa, FL 33612, USA
    Genet Test Mol Biomarkers 17:367-75. 2013
    ..This study describes practitioner knowledge and practices related to BRCA testing and management and explores how training may contribute to practice patterns...
  3. doi request reprint Early onset breast cancer in a registry-based sample of African-american women: BRCA mutation prevalence, and other personal and system-level clinical characteristics
    Tuya Pal
    Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Breast J 19:189-92. 2013
    ..Finally, the limited number of patients referred for genetic counseling prior to surgical treatment for breast cancer may represent a missed clinical opportunity to inform surgical decisions...
  4. pmc Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer
    T Pal
    Departments of Cancer Epidemiology, Biostatistics, Anatomic Pathology and Experimental Therapeutics, Moffitt Cancer Center, MRC CANCONT, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Br J Cancer 107:1783-90. 2012
    ..We sought to estimate the frequency and characteristics of HNPCC gene mutations in a population-based sample of women with epithelial ovarian cancer...
  5. ncbi request reprint Genetic risk assessments in individuals at high risk for inherited breast cancer in the breast oncology care setting
    Tuya Pal
    Population Sciences Department of Cancer Epidemiology, Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Control 19:255-66. 2012
    ..Knowledge about the risk for hereditary cancer at or as close as possible to the time of diagnosis allows patients access to the most risk reduction options available...
  6. doi request reprint Recruitment of black women for a study of inherited breast cancer using a cancer registry-based approach
    Tuya Pal
    Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Genet Test Mol Biomarkers 15:69-77. 2011
    ..We sought to understand the factors associated with recruitment activities while conducting a registry-based study of black women found to have breast cancer <age 50 to investigate mutations in the BRCA1 and BRCA2 genes...
  7. pmc Systematic review and meta-analysis of ovarian cancers: estimation of microsatellite-high frequency and characterization of mismatch repair deficient tumor histology
    Tuya Pal
    H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Clin Cancer Res 14:6847-54. 2008
    ....
  8. doi request reprint BRCA1/2 in high-risk African American women with breast cancer: providing genetic testing through various recruitment strategies
    Tuya Pal
    H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Genet Test 12:401-7. 2008
    ....
  9. pmc A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer
    Tuya Pal
    Department of Cancer Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Cancer 113:733-42. 2008
    ..The ability to make such distinctions may be of diagnostic, prognostic, and therapeutic utility...
  10. ncbi request reprint The presence of germ line mosaicism in cleidocranial dysplasia
    T Pal
    Department of Pediatrics, All Children s Hospital, College of Medicine, The University of South Florida, St Petersburg, Florida 33612, USA
    Clin Genet 71:589-91. 2007
    ..We present the first case of confirmed germ line mosaicism in CCD...
  11. doi request reprint Evaluation of phone-based genetic counselling in African American women using culturally tailored visual aids
    T Pal
    Moffitt Cancer Center, Division of Cancer Prevention and Control, Tampa, Florida, USA
    Clin Genet 78:124-31. 2010
    ..Our results indicate that phone-based GC supplemented by a culturally targeted visual aid is an effective means of improving knowledge about HBOC in young AA women with invasive breast cancer...
  12. pmc Improved survival in BRCA2 carriers with ovarian cancer
    Tuya Pal
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Fam Cancer 6:113-9. 2007
    ..The objective of this study was to investigate survival of ovarian cancer patients with BRCA1 and BRCA2 mutations compared to those without mutations in a population-based sample of incident epithelial ovarian cancer cases...
  13. ncbi request reprint BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases
    Tuya Pal
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33617, USA
    Cancer 104:2807-16. 2005
    ..To address this gap, the authors conducted a population-based study of 232 incident epithelial ovarian carcinomas in the Tampa Bay area...
  14. doi request reprint Association Between IHC and MSI Testing to Identify Mismatch Repair-Deficient Patients with Ovarian Cancer
    Ji Hyun Lee
    1 Department of Biostatistics, H Lee Moffitt Cancer Center, Tampa, Florida
    Genet Test Mol Biomarkers 18:229-35. 2014
    ..Results support the need for validation studies before routine screening of ovarian tumors is implemented in clinical practice for the purpose of identifying Lynch syndrome. ..
  15. doi request reprint Fertility in women with BRCA mutations: a case-control study
    Tuya Pal
    Department of Cancer Epidemiology and Genetics, Moffitt Cancer Center, University of South Florida College of Medicine, Tampa, Florida, USA
    Fertil Steril 93:1805-8. 2010
    ..To investigate whether or not fertility is reduced in women carrying mutations in the BRCA genes (BRCA1 and BRCA2), compared with noncarrier family members...
  16. ncbi request reprint Uncertainty in the utility of immunohistochemistry in mismatch repair protein expression in epithelial ovarian cancer
    Domenico Coppola
    Department of Anatomic Pathology, H Lee Moffitt Cancer Center, Tampa, FL, USA
    Anticancer Res 32:4963-9. 2012
    ..We evaluated MMR protein expression in three population-based samples of epithelial ovarian cancers...
  17. ncbi request reprint BRCA1 and BRCA2 mutations in a study of African American breast cancer patients
    Tuya Pal
    Lifetime Cancer Screening and Prevention Center, H Lee Moffitt Cancer Center and Research Institute, 4117 East Fowler Avenue, Tampa, FL 33617, USA
    Cancer Epidemiol Biomarkers Prev 13:1794-9. 2004
    ....
  18. doi request reprint High-risk consumers' perceptions of preimplantation genetic diagnosis for hereditary cancers: a systematic review and meta-analysis
    Gwendolyn P Quinn
    Division of Cancer Prevention and Control, Moffitt Cancer Center, Tampa, Florida, USA
    Genet Med 14:191-200. 2012
    ....
  19. doi request reprint Development of a culturally tailored genetic counseling booklet about hereditary breast and ovarian cancer for Black women
    Jennifer Permuth-Wey
    Department of Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Am J Med Genet A 152:836-45. 2010
    ..Further evaluation of the utility of our booklet in increasing awareness and understanding of HBOC and promoting informed decision-making regarding genetic testing and medical management among Black women is needed...
  20. pmc A pilot study to examine patient awareness and provider discussion of the impact of cancer treatment on fertility in a registry-based sample of African American women with breast cancer
    Susan T Vadaparampil
    Department of Oncologic Science, College of Medicine, University of South Florida, Tampa, FL, USA
    Support Care Cancer 20:2559-64. 2012
    ..e., ≤age 40), little is known about patient awareness of or provider discussion related to fertility in this group. We examined African American women's awareness of the possible impact of cancer treatment on fertility...
  21. doi request reprint Development of a brochure for increasing awareness of inherited breast cancer in black women
    Susan T Vadaparampil
    Division of Cancer Prevention and Control, Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
    Genet Test Mol Biomarkers 15:59-67. 2011
    ..Further, the complexity of our subject matter (i.e., inherited breast and ovarian cancer) underscores the importance of using inviting visuals and personal vignettes, while maintaining a simple and clear message...
  22. pmc Colorectal cancer survivors' interest in genetic testing for hereditary cancer: implications for universal tumor screening
    Deborah Cragun
    Department of Community and Family Health, College of Public Health, University of South Florida, Tampa, Florida, USA
    Genet Test Mol Biomarkers 16:493-9. 2012
    ..This study explores interest in genetic testing for hereditary CRC among CRC patients who have never received genetic counseling or testing...
  23. doi request reprint Educational needs and preferred methods of learning among Florida practitioners who order genetic testing for hereditary breast and ovarian cancer
    Deborah Cragun
    Community and Family Health, College of Public Health, University of South Florida, Tampa, FL, USA
    J Cancer Educ 28:690-7. 2013
    ..These results can be used to enhance participation of community-based providers in educational training programs by targeting educational resources to the most preferred format...
  24. pmc Risk terminology in biobanking and genetic research: what's in a name?
    Gwendolyn P Quinn
    Division of Cancer Prevention and Control, Moffitt Cancer Center, Tampa, FL 33612, USA
    Am J Med Genet A 161:2095-8. 2013
    ....
  25. pmc Sampling strategies for tissue microarrays to evaluate biomarkers in ovarian cancer
    Jenny Permuth-Wey
    H Lee Moffitt Cancer Center, Tampa, FL, USA
    Cancer Epidemiol Biomarkers Prev 18:28-34. 2009
    ..Tissue microarrays (TMA) enable rapid analysis of biomarkers in large-scale studies involving archival tumor specimens, however, their utility in heterogeneous tumors such as ovarian cancer is limited...
  26. pmc Updating and refining a study brochure for a cancer registry-based study of BRCA mutations among young African American breast cancer patients: lessons learned
    Susan T Vadaparampil
    Division of Cancer Prevention and Control, Moffitt Cancer Center, 12902 Magnolia Drive, MRC CANCONT, Tampa, FL, 33612, USA
    J Community Genet 1:63-71. 2010
    ..This approach can be readily adapted to develop study recruitment materials for individuals from a variety of cultural and ethnic backgrounds...
  27. ncbi request reprint Estrogen bioactivation, genetic polymorphisms, and ovarian cancer
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33602, USA
    Cancer Epidemiol Biomarkers Prev 14:2536-43. 2005
    ..015). Although preliminary, this study provides some support for the hypothesis that low-penetrance susceptibility alleles may influence risk of epithelial ovarian cancer...
  28. ncbi request reprint Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma
    Tuya Pal
    Cancer 100:2485-6; author reply 2486. 2004

Research Grants6

  1. Clinical Relevance of Mismatch Repair in Ovarian Cancer
    Tuya Pal; Fiscal Year: 2007
    ..The achievement of these goals will provide the expertise needed for a career as a successful, independent investigator committed to academic research. ..
  2. Ovarian Cancer and Mismatch Repair Deficiency
    Tuya Pal; Fiscal Year: 2009
    ..abstract_text> ..