Martine Extermann

Summary

Affiliation: H. Lee Moffitt Cancer Center and Research Institute
Country: USA

Publications

  1. doi request reprint Metabolic syndrome and cancer: from bedside to bench and back
    Martine Extermann
    Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA
    Interdiscip Top Gerontol 38:49-60. 2013
  2. doi request reprint Integrating a geriatric evaluation in the clinical setting
    Martine Extermann
    Moffitt Cancer Center, Tampa, FL 33612, USA Electronic address
    Semin Radiat Oncol 22:272-6. 2012
  3. doi request reprint Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score
    Martine Extermann
    Senior Adult Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, Florida 33612, USA
    Cancer 118:3377-86. 2012
  4. doi request reprint Cancer in nonagenarians: profile, treatments and outcomes
    Martine Extermann
    Department of Oncology Sciences, University of South Florida, USA
    Crit Rev Oncol Hematol 75:160-4. 2010
  5. doi request reprint Basic assessment of the older cancer patient
    Martine Extermann
    Moffitt Cancer Center, University of South Florida, Tampa, USA
    Curr Treat Options Oncol 12:276-85. 2011
  6. ncbi request reprint The abbreviated comprehensive geriatric assessment (aCGA) for use in the older cancer patient as a prescreen: scoring and interpretation
    Janine A Overcash
    College of Nursing, University of South Florida, Tampa, FL 33612 4766, USA
    Crit Rev Oncol Hematol 59:205-10. 2006
  7. ncbi request reprint A comprehensive geriatric intervention detects multiple problems in older breast cancer patients
    Martine Extermann
    Senior Adult Oncology, H Lee Moffitt Cancer Center, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Crit Rev Oncol Hematol 49:69-75. 2004
  8. doi request reprint Comprehensive geriatric assessment and its clinical impact in oncology
    Jane Jijun Liu
    Senior Adult Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, FL 33612, USA
    Clin Geriatr Med 28:19-31. 2012
  9. ncbi request reprint Comprehensive geriatric assessment for older patients with cancer
    Martine Extermann
    H Lee Moffitt Cancer Center, University of South Florida, Tampa, FL 33612, USA
    J Clin Oncol 25:1824-31. 2007
  10. ncbi request reprint Pilot testing of the computerized cognitive test Microcog in chemotherapy-treated older cancer patients
    Martine Extermann
    Senior Adult Oncology, H Lee Moffitt Cancer Center, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Crit Rev Oncol Hematol 54:137-43. 2005

Collaborators

Detail Information

Publications29

  1. doi request reprint Metabolic syndrome and cancer: from bedside to bench and back
    Martine Extermann
    Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA
    Interdiscip Top Gerontol 38:49-60. 2013
    ..Bench-to-bedside studies are beginning to shed some light on that aspect, and some therapeutic trials are beginning to exploit the lessons learned...
  2. doi request reprint Integrating a geriatric evaluation in the clinical setting
    Martine Extermann
    Moffitt Cancer Center, Tampa, FL 33612, USA Electronic address
    Semin Radiat Oncol 22:272-6. 2012
    ..A practical way of implementing a multidisciplinary consultation is reviewed, and future directions are discussed...
  3. doi request reprint Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score
    Martine Extermann
    Senior Adult Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, Florida 33612, USA
    Cancer 118:3377-86. 2012
    ..Tools are lacking to assess the individual risk of severe toxicity from chemotherapy. Such tools would be especially useful for older patients, who vary considerably in terms of health status and functional reserve...
  4. doi request reprint Cancer in nonagenarians: profile, treatments and outcomes
    Martine Extermann
    Department of Oncology Sciences, University of South Florida, USA
    Crit Rev Oncol Hematol 75:160-4. 2010
    ..1%). In conclusion, our nonagenarians underwent a broad range of treatments with low treatment related mortality. Advanced cancer still limits the survival of nonagenarians. Second cancers are frequent in older cancer survivors...
  5. doi request reprint Basic assessment of the older cancer patient
    Martine Extermann
    Moffitt Cancer Center, University of South Florida, Tampa, USA
    Curr Treat Options Oncol 12:276-85. 2011
    ..First a short screening with a tested screening instrument. Then further work-up of the geriatric findings in parallel with the oncology work-up to define an integrated treatment plan...
  6. ncbi request reprint The abbreviated comprehensive geriatric assessment (aCGA) for use in the older cancer patient as a prescreen: scoring and interpretation
    Janine A Overcash
    College of Nursing, University of South Florida, Tampa, FL 33612 4766, USA
    Crit Rev Oncol Hematol 59:205-10. 2006
    ..The abbreviated CGA (aCGA) can be used as a prescreening assessment to identify patients who would most benefit from the complete CGA...
  7. ncbi request reprint A comprehensive geriatric intervention detects multiple problems in older breast cancer patients
    Martine Extermann
    Senior Adult Oncology, H Lee Moffitt Cancer Center, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Crit Rev Oncol Hematol 49:69-75. 2004
    ..CONCLUSIONS: Older patients with early breast cancer have a high prevalence of comorbidity. A CGA with follow-up has potential for improving the treatment and prognosis of these patients and is feasible in an academic oncology setting...
  8. doi request reprint Comprehensive geriatric assessment and its clinical impact in oncology
    Jane Jijun Liu
    Senior Adult Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, FL 33612, USA
    Clin Geriatr Med 28:19-31. 2012
    ..Further studies are needed using a CGA to (1) guide and test interventions to improve the care of older adults with cancer and (2) evaluate the impact of cancer therapy on geriatric assessment domains...
  9. ncbi request reprint Comprehensive geriatric assessment for older patients with cancer
    Martine Extermann
    H Lee Moffitt Cancer Center, University of South Florida, Tampa, FL 33612, USA
    J Clin Oncol 25:1824-31. 2007
    ..This article discusses recent advances on the use of a CGA in older patients with cancer...
  10. ncbi request reprint Pilot testing of the computerized cognitive test Microcog in chemotherapy-treated older cancer patients
    Martine Extermann
    Senior Adult Oncology, H Lee Moffitt Cancer Center, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Crit Rev Oncol Hematol 54:137-43. 2005
    ..Computerized cognitive tests are available and could simplify cooperative group studies on the matter, but have not been applied to older cancer patients...
  11. ncbi request reprint Decision analysis for cancer prevention and cancer treatment in the elderly
    Martine Extermann
    Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Cancer Treat Res 124:223-32. 2005
  12. pmc Individual differences in well-being in older breast cancer survivors
    Elizabeth A Perkins
    School of Aging Studies, University of South Florida, 4202 East Fowler Avenue, MHC 1308, Tampa, FL 33612, USA
    Crit Rev Oncol Hematol 62:74-83. 2007
    ....
  13. ncbi request reprint Geriatric assessment with focus on instrument selectivity for outcomes
    Martine Extermann
    H Lee Moffitt Cancer Center, Tampa, Florida 33612, USA
    Cancer J 11:474-80. 2005
    ..Some evidence is beginning to appear as to the impact a comprehensive geriatric assessment could have on the oncologic management of older patients with cancer...
  14. doi request reprint Phase 2 trial of docetaxel and gefitinib in the first-line treatment of patients with advanced nonsmall-cell lung cancer (NSCLC) who are 70 years of age or older
    George R Simon
    Thoracic Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer 112:2021-9. 2008
    ..The primary endpoint was response rate (RR). Secondary endpoints were overall survival (OS) and progression-free survival (PFS)...
  15. ncbi request reprint The abbreviated comprehensive geriatric assessment (aCGA): a retrospective analysis
    Janine A Overcash
    College of Nursing, University of South Florida, 12901 Bruce B Downs Blvd, MDC 22, Tampa, FL 33612 4766, USA
    Crit Rev Oncol Hematol 54:129-36. 2005
    ..A comprehensive geriatric assessment (CGA) is a multidimensional assessment that is designed to detect health problems. A barrier to conducting the CGA is the length of time required to complete the entire assessment...
  16. ncbi request reprint Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG)
    Martine Extermann
    H Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Crit Rev Oncol Hematol 55:241-52. 2005
    ..As more and more cancers occur in elderly people, oncologists are increasingly confronted with the necessity of integrating geriatric parameters in the treatment of their patients...
  17. ncbi request reprint Comorbidity and geriatric assessment in the elderly patient over the age of 70
    Martine Extermann
    Senior Adult Oncology, H Lee Moffit Cancer Center, Tampa, FL, USA
    Tumori 88:S9. 2002
  18. ncbi request reprint Older patients, cognitive impairment, and cancer: an increasingly frequent triad
    Martine Extermann
    Departments of Oncology and Medicine, University of South Florida, H Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
    J Natl Compr Canc Netw 3:593-6. 2005
    ..Cancer patients with cognitive impairment are at high risk of concomitant depression...
  19. ncbi request reprint Biological basis of the association of cancer and aging comorbidity
    Martine Extermann
    Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Cancer Treat Res 124:173-86. 2005
  20. ncbi request reprint Comprehensive geriatric assessment basics for the cancer professional
    Martine Extermann
    Moffitt Cancer Center, Tampa, FL 33612, USA
    J Oncol Manag 12:13-7. 2003
    ..It is, for example, part of the National Comprehensive Cancer Network (NCCN) guidelines for the elderly'. This article offers a primer on CGA for the reader unfamiliar with the approach in an oncologic setting...
  21. ncbi request reprint Are older French patients as willing as older American patients to undertake chemotherapy?
    Martine Extermann
    H Lee Moffitt Cancer Center, Tampa, FL, USA
    J Clin Oncol 21:3214-9. 2003
    ..A view often held in Europe is that older Europeans are less willing than older Americans to undertake chemotherapy. This study assesses whether this view is valid...
  22. ncbi request reprint Can older cancer patients tolerate chemotherapy? A prospective pilot study
    Hongbin Chen
    Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, Florida 33612, USA
    Cancer 97:1107-14. 2003
    ..This prospective pilot study evaluated the changes in functional, mental, nutritional, and comorbid status, as well as the quality of life (QOL), in geriatric oncology patients receiving chemotherapy...
  23. ncbi request reprint Studies of comprehensive geriatric assessment in patients with cancer
    Martine Extermann
    Senior Adult Oncology Program, H Lee Moffitt Cancer Center Research Institute, Tampa, FL 33612, USA
    Cancer Control 10:463-8. 2003
    ..The comprehensive geriatric assessment (CGA) has been developed to individually assess the health status of older patients...
  24. ncbi request reprint Management issues for elderly patients with breast cancer
    Martine Extermann
    Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Curr Treat Options Oncol 5:161-9. 2004
    ..The cumulative result of the introduction of these new agents, at a population level, is a 7.5-month increase in the median survival time of patients with metastatic breast cancer over the past decade...
  25. ncbi request reprint Interaction between comorbidity and cancer
    Martine Extermann
    Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Control 14:13-22. 2007
    ..There is mounting evidence that comorbidity interacts with risk, survival, disease progression, and treatment of elderly patients with cancer. The strength of many of these interactions increases with age...
  26. ncbi request reprint Treating advanced breast cancer in the older woman
    Martine Extermann
    Moffitt Cancer Center, Tampa, Florida 33612, USA
    Oncology (Williston Park) 20:1355-60; discussion 1360, 1362, 1367-8. 2006
    ..For most patients in this setting, sequential single-agent chemotherapy appears at this time to be the preferred course of treatment...
  27. ncbi request reprint Biological screening and impact in elderly cancer patients
    Anne Chantal Braud
    H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
    Cancer Treat Res 124:165-71. 2005
  28. ncbi request reprint Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection
    Maria Friberg
    Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Int J Cancer 101:151-5. 2002
    ..Our study provides evidence for a novel mechanism whereby tumors evade rejection by the immune system, and suggests the possibility that inhibiting IDO may be developed as an anti-cancer immunotherapeutic strategy...
  29. ncbi request reprint Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma
    Scott J Antonia
    Interdisciplinary Oncology Program and Genitourinary Program, H Lee Moffitt Cancer Center, Tampa, Florida 33612, USA
    J Urol 167:1995-2000. 2002
    ..We conducted a phase I clinical trial testing this approach in patients with metastatic renal cell carcinoma...