Kathleen M Egan

Summary

Affiliation: H. Lee Moffitt Cancer Center and Research Institute
Country: USA

Publications

  1. pmc Rare TP53 genetic variant associated with glioma risk and outcome
    Kathleen M Egan
    Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    J Med Genet 49:420-1. 2012
  2. pmc Statistical learning techniques applied to epidemiology: a simulated case-control comparison study with logistic regression
    John J Heine
    H, Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    BMC Bioinformatics 12:37. 2011
  3. doi request reprint Vitamin D and melanoma
    Kathleen M Egan
    Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Ann Epidemiol 19:455-61. 2009
  4. pmc Cancer susceptibility variants and the risk of adult glioma in a US case-control study
    Kathleen M Egan
    Department of Cancer Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    J Neurooncol 104:535-42. 2011
  5. pmc Toenail iron, genetic determinants of iron status, and the risk of glioma
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA
    Cancer Causes Control 24:2051-8. 2013
  6. pmc Early life exposures and the risk of adult glioma
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    Eur J Epidemiol 28:753-8. 2013
  7. pmc An exploratory analysis of common genetic variants in the vitamin D pathway including genome-wide associated variants in relation to glioma risk and outcome
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Causes Control 23:1443-9. 2012
  8. pmc Prediagnostic body weight and survival in high grade glioma
    Erin M Siegel
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612 9416, USA
    J Neurooncol 114:79-84. 2013
  9. pmc Reproductive factors and risk of primary brain tumors in women
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    J Neurooncol 118:297-304. 2014
  10. pmc Circadian pathway genes in relation to glioma risk and outcome
    Melissa H Madden
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    Cancer Causes Control 25:25-32. 2014

Collaborators

Detail Information

Publications16

  1. pmc Rare TP53 genetic variant associated with glioma risk and outcome
    Kathleen M Egan
    Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    J Med Genet 49:420-1. 2012
    ..52; p=0.009) when compared to non-carriers. The rs78378222 SNP is the first confirmed rare susceptibility variant in glioma. Results may shed light on the aetiology and progression of these tumours...
  2. pmc Statistical learning techniques applied to epidemiology: a simulated case-control comparison study with logistic regression
    John J Heine
    H, Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    BMC Bioinformatics 12:37. 2011
    ..Because the LR model has an important epidemiologic interpretation, the SL method was modified to produce the analogous interpretation and generate odds ratios for comparison...
  3. doi request reprint Vitamin D and melanoma
    Kathleen M Egan
    Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Ann Epidemiol 19:455-61. 2009
    ..This article reviews current evidence that vitamin D might play a preventive role in the development of melanoma or affect tumor aggressiveness or melanoma patient outcomes...
  4. pmc Cancer susceptibility variants and the risk of adult glioma in a US case-control study
    Kathleen M Egan
    Department of Cancer Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    J Neurooncol 104:535-42. 2011
    ..Stratification by broad histological subgroups may shed light on molecular mechanisms and assist in the discovery of novel loci in future studies of genetic susceptibility variants in glioma...
  5. pmc Toenail iron, genetic determinants of iron status, and the risk of glioma
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA
    Cancer Causes Control 24:2051-8. 2013
    ..This study examined the associations of iron levels measured in toenails and genetic variants linked to body iron stores with risk of glioma in a clinic-based case-control study...
  6. pmc Early life exposures and the risk of adult glioma
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    Eur J Epidemiol 28:753-8. 2013
    ..The current findings lend further support to a growing body of evidence that early exposure to childhood infections reduces the risk of glioma onset in children and adults...
  7. pmc An exploratory analysis of common genetic variants in the vitamin D pathway including genome-wide associated variants in relation to glioma risk and outcome
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Causes Control 23:1443-9. 2012
    ..In vitro evidence is consistent with a similar protective function in glioma; however, no study has yet examined the potential role of vitamin D in glioma...
  8. pmc Prediagnostic body weight and survival in high grade glioma
    Erin M Siegel
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612 9416, USA
    J Neurooncol 114:79-84. 2013
    ..The current findings linking prediagnostic body weight with mortality in high-grade glioma warrant further research...
  9. pmc Reproductive factors and risk of primary brain tumors in women
    Gabriella M Anic
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    J Neurooncol 118:297-304. 2014
    ..Current findings are consistent with a limited role for hormones in the onset of brain tumors in women. Results contribute to a growing body of evidence that a later age at menarche increases the risk of glioma in women. ..
  10. pmc Circadian pathway genes in relation to glioma risk and outcome
    Melissa H Madden
    Department of Cancer Epidemiology, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    Cancer Causes Control 25:25-32. 2014
    ..We evaluated common genetic variants in the circadian gene pathway for associations with glioma risk and patient outcome in a US clinic-based case-control study...
  11. pmc SWI/SNF gene variants and glioma risk and outcome
    Ernest K Amankwah
    Department of Cancer Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Cancer Epidemiol 37:162-5. 2013
    ..However, the role of germline genetic variants in this complex in relation to cancer risk is not well studied...
  12. pmc A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma
    Jennifer Permuth-Wey
    Department of Cancer Epidemiology, Division of Population Sciences, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, MRC CANCONT, Tampa, FL 33612 9416, USA
    J Neurooncol 105:639-46. 2011
    ..17, P = 0.002)). We provide novel data suggesting rs2910164 genotype may contribute to glioma susceptibility and outcome. Future studies are warranted to replicate these findings and characterize mechanisms underlying these associations...
  13. pmc Tea consumption and risk of breast cancer
    Nagi Kumar
    Department of Health Outcomes and Behavior, Population Sciences Division, Moffitt Cancer Center, 12902 Magnolia Drive, MRC CANCONT, Tampa, FL 33612, USA
    Cancer Epidemiol Biomarkers Prev 18:341-5. 2009
    ..The purpose of our study was to examine the association of regular tea consumption with the risk of breast cancer in a large population-based case-control study from the United States...
  14. doi request reprint Family history is a significant risk factor for pancreatic cancer: results from a systematic review and meta-analysis
    Jennifer Permuth-Wey
    Department of Cancer Epidemiology and Genetics, H Lee Moffitt Cancer Center and Research Institute, MRC CAN CONT, Tampa, FL 33612, USA
    Fam Cancer 8:109-17. 2009
    ..Those at highest risk may be referred to screening programs and studies; these are important steps toward early detection and greater odds of surviving this disease...
  15. pmc Gene variants in angiogenesis and lymphangiogenesis and cutaneous melanoma progression
    Jong Y Park
    Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Cancer Epidemiol Biomarkers Prev 22:827-34. 2013
    ..We investigated associations between genetic variants in these pathways with sentinel lymph node (SLN) metastasis and mortality in 2 independent series of patients with melanoma...
  16. pmc Association of CYP1B1 haplotypes and breast cancer risk in Caucasian women
    Yifan Huang
    H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Cancer Epidemiol Biomarkers Prev 18:1321-3. 2009
    ..015), with significant associations identified for 2 uncommon haplotypes comprising 4% of the controls. Results suggest that genetic variation in CYP1B1 has at most a minor influence on breast cancer susceptibility among Caucasian women...

Research Grants10

  1. Gene Interactions, Estrogen, and Risk of Breast Cancer
    Kathleen Egan; Fiscal Year: 2004
    ..abstract_text> ..
  2. Southeast Region Case-Control Study of Adult Glioma
    Kathleen M Egan; Fiscal Year: 2010
    ..Based in a high incidence region, the study may identify novel environmental risk factors and offer new insights on prevention and treatment for a leading fatal cancer in the US. ..
  3. Southeast Region Case-Control Study of Adult Glioma
    Kathleen Egan; Fiscal Year: 2009
    ..Based in a high incidence region, the study may identify novel environmental risk factors and offer new insights on prevention and treatment for a leading fatal cancer in the US. ..
  4. Gene Interactions, Estrogen, and Risk of Breast Cancer
    Kathleen Egan; Fiscal Year: 2006
    ..abstract_text> ..
  5. Serum Vitamin D and Mortality from Eye Melanoma
    Kathleen Egan; Fiscal Year: 2006
    ..If the proposed hypotheses are supported, findings may offer novel insights, and point to new strategies for cancer control. ..
  6. Serum Vitamin D and Mortality from Eye Melanoma
    Kathleen Egan; Fiscal Year: 2007
    ..If the proposed hypotheses are supported, findings may offer novel insights, and point to new strategies for cancer control. ..
  7. Southeast Region Case-Control Study of Adult Glioma
    Kathleen Egan; Fiscal Year: 2007
    ..Based in a high incidence region, the study may identify novel environmental risk factors and offer new insights on prevention and treatment for a leading fatal cancer in the US. ..
  8. Gene Interactions, Estrogen, and Risk of Breast Cancer
    Kathleen Egan; Fiscal Year: 2005
    ..abstract_text> ..
  9. Southeast Region Case-Control Study of Adult Glioma
    Kathleen Egan; Fiscal Year: 2009
    ..Based in a high incidence region, the study may identify novel environmental risk factors and offer new insights on prevention and treatment for a leading fatal cancer in the US. ..