Research Topics
| Lodovico BalducciSummaryAffiliation: H. Lee Moffitt Cancer Center and Research Institute Country: USA Publications
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Detail Information
Publications
Frailty: a common pathway in aging and cancerLodovico Balducci
Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA
Interdiscip Top Gerontol 38:61-72. 2013..Studies are needed to establish whether the construct of frailty proposed by Fried et al. may be predictive of decreased cancer-independent survival and of decreased treatment tolerance in older cancer patients...
Rehabilitation of older cancer patientsLodovico Balducci
H Lee Moffitt Cancer Center, Tampa, FL, USA
Acta Oncol 52:233-8. 2013..Prevention and management of fatigue, cognitive decline and peripheral neuropathy appear as the most important issue to prolong the active life expectancies of these individuals...
Beyond quality of life: the meaning of death and suffering in palliative careLodovico Balducci
Department of Interdisciplinary Oncology, University of South Florida College of Medicine, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
Asian Pac J Cancer Prev 11:41-4. 2010..Qualitative research in its various forms, including open ended questions, content analysis and mainly personal narrative are the most promising forms of research to comprehend spiritual and existential pain...
Medicine and spirituality: a personal adventureLodovico Balducci
Department of Interdisciplinary Oncology, University of South Florida College of Medicine, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA For correspondence
Asian Pac J Cancer Prev 11:79-80. 2010..Like Chesterton describes in his book 'Orthodoxy' the discovery of the spiritual dimension in medicine was a long pigrimage home, toward myself, to learn how to love and dignify myself...
Supportive care in elderly cancer patientsLodovico Balducci
Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
Curr Opin Oncol 21:310-7. 2009..To establish the supportive needs of older cancer patients receiving antineoplastic treatment. This topic is very timely because cancer is a disease of the elderly and the size of the older population is increasing throughout the world...
Assessment and treatment of elderly patients with cancerLodovico Balducci
Senior Adult Oncology Program, Moffitt Cancer Center and Research Institute, MCC SA Program, Tampa, Florida, USA
Surg Oncol 19:117-23. 2010....
Bone complications of cancer treatment in the elderlyLodovico Balducci
University of South Florida, College of Medicine, Tampa, Florida, USA
Oncology (Williston Park) 24:741-7. 2010..This may include calcium and vitamin D supplementation for mild forms of osteopenia, and bisphosphonate therapy or denosumab (Prolia) for more advanced osteopenia and osteoporosis...
Treating elderly patients with hormone sensitive breast cancer: what do the data show?L Balducci
H Lee Moffitt Cancer Center and Research Institute, Senior Adult Oncology Program, 12902 Magnolia Drive, Tampa, FL 33612, USA
Cancer Treat Rev 35:47-56. 2009....
ESH-SIOG International Conference on Haematological Malignancies in the ElderlyLodovico Balducci
Division of Geriatric Oncology, Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, FL, USA
Expert Rev Hematol 3:675-7. 2010....
Pharmacology of antineoplastic medications in older cancer patientsLodovico Balducci
Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, Florida 33612, USA
Oncology (Williston Park) 23:78-85. 2009....
A comprehensive geriatric intervention detects multiple problems in older breast cancer patientsMartine Extermann
Senior Adult Oncology, H Lee Moffitt Cancer Center, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
Crit Rev Oncol Hematol 49:69-75. 2004..CONCLUSIONS: Older patients with early breast cancer have a high prevalence of comorbidity. A CGA with follow-up has potential for improving the treatment and prognosis of these patients and is feasible in an academic oncology setting...
Cancer and age: general considerationsSarah Hoffe
Moffitt Cancer Center at International Plaza, Tampa, FL 33612, USA
Clin Geriatr Med 28:1-18. 2012..It may also be essential in caring for a host of older cancer survivors. In France, this cooperation is already a reality that finds its expression in a network of units of oncogeriatrics distributed throughout the country...
Management of cancer in the elderlyLodovico Balducci
Division of Geriatric Oncology, Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H Lee Moffitt Cancer Center, Tampa, USA
Oncology (Williston Park) 20:135-43; discussion 144, 146, 151-2. 2006..Age is not a contraindication to cancer treatment: With appropriate caution, older individuals may benefit from cytotoxic chemotherapy to the same extent as the youngest patients...
Cancer chemotherapy in elderly cancer patientsLodovico Balducci
Senior Adult Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
J Oncol Manag 14:35-8. 2005..This approach is outlined in the National Cancer Center Network guidelines for the management of cancer in the older person...
Individual differences in well-being in older breast cancer survivorsElizabeth A Perkins
School of Aging Studies, University of South Florida, 4202 East Fowler Avenue, MHC 1308, Tampa, FL 33612, USA
Crit Rev Oncol Hematol 62:74-83. 2007....
Management of chemotherapy-induced neutropenia in the older cancer patientLodovico Balducci
Senior Adult Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
Oncology (Williston Park) 20:26-31. 2006..In this article we explore the management of neutropenia and neutropenic infections in older cancer patients, as well as review the causes and the risk of this complication...
Senior adult oncology clinical practice guidelines in oncologyLodovico Balducci
H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
J Natl Compr Canc Netw 3:572-90. 2005
Pilot testing of the computerized cognitive test Microcog in chemotherapy-treated older cancer patientsMartine Extermann
Senior Adult Oncology, H Lee Moffitt Cancer Center, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
Crit Rev Oncol Hematol 54:137-43. 2005..Computerized cognitive tests are available and could simplify cooperative group studies on the matter, but have not been applied to older cancer patients...
Guidelines for the management of the older cancer patientLodovico Balducci
Senior Adult Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
Cancer Treat Res 124:233-56. 2005
Hemopoiesis and agingLodovico Balducci
Senior Adult Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
Cancer Treat Res 124:109-34. 2005
Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) scoreMartine Extermann
Senior Adult Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, Florida 33612, USA
Cancer 118:3377-86. 2012..Tools are lacking to assess the individual risk of severe toxicity from chemotherapy. Such tools would be especially useful for older patients, who vary considerably in terms of health status and functional reserve...
Management of cancer pain in geriatric patientsLodovico Balducci
H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
J Support Oncol 1:175-91. 2003..In the conclusion, the American Geriatrics Society's guidelines for the management of pain in older individuals will be examined and a research agenda outlined...
Elderly cancer patients receiving chemotherapy benefit from first-cycle pegfilgrastimLodovico Balducci
H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Oncologist 12:1416-24. 2007....
Fatigue, weight gain, lethargy and amenorrhea in breast cancer patients on chemotherapy: is subclinical hypothyroidism the culprit?Nagi Kumar
Department of Cancer Control, University of South Florida, University of South Florida College of Medicine, Tampa, FL 33612 9497, USA
Breast Cancer Res Treat 83:149-59. 2004....
Increased risk of myelotoxicity in elderly patients with non-Hodgkin lymphomaLodovico Balducci
Senior Adult Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
Cancer 100:6-11. 2004
Myelosuppression and its consequences in elderly patients with cancerLodovico Balducci
Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
Oncology (Williston Park) 17:27-32. 2003..Such prophylaxis should be routinely considered in elderly patients with cancer treated with myelosuppressive chemotherapy...
Cancer-related anemia: special considerations in the elderlyLodovico Balducci
Division of Geriatric Oncology, Department of Interdisciplinary Oncology, University of South Florida, College of Medicine, H Lee Moffitt Cancer Center, Tampa, Florida 33612 9416, USA
Oncology (Williston Park) 21:81-6, 90; discussion 90, 100,104. 2007....
Aging, frailty, and chemotherapyLodovico Balducci
Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Cancer Control 14:7-12. 2007..In many cases, elderly individuals have not been offered life-saving interventions due to the assumption that these treatments would be too toxic to tolerate...
Supportive care of the older cancer patientLodovico Balducci
H Lee Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, 12902 Magnolia Drive, Tampa, FL 33612, USA
Crit Rev Oncol Hematol 48:S65-70. 2003..When toxicity is properly prevented, cytotoxic chemotherapy may be as effective in older individuals as it is in the younger ones...
Transfusion independence in patients with myelodysplastic syndromes: impact on outcomes and quality of lifeLodovico Balducci
Department of Interdisciplinary Oncology, Geriatric Section, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 9497, USA
Cancer 106:2087-94. 2006..Newer treatments have the potential to improve the care of patients with MDS by alleviating the clinical, economic, and quality-of-life consequences of long-term RBC transfusion dependence...
Prevention of cancer in the older personLodovico Balducci
Interdisciplinary Oncology Program, University of South Florida College of Medicine, Tampa, Florida, USA
Cancer J 11:442-8. 2005..The value of screening asymptomatic individuals for lung and ovarian cancer is explored in ongoing clinical trials...
The prevalence and correlates of fatigue in older cancer patientsDaniela Respini
Psychosocial and Palliative Care Program, and Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute and University of South Florida, Tampa, FL, USA
Crit Rev Oncol Hematol 47:273-9. 2003..to assess the prevalence and correlates of fatigue in cancer patients aged 60 and older during outpatient treatment with chemotherapy or pamidronate...
Course of fatigue in women receiving chemotherapy and/or radiotherapy for early stage breast cancerKristine A Donovan
Department of Psychology, University of South Florida, Tampa, USA
J Pain Symptom Manage 28:373-80. 2004....
An overlooked problem: anemia in the elderly patient with cancerLodovico Balducci
Department of Interdisciplinary Oncology, University of South Florida College of Medicine, USA
J Support Oncol 5:115-6. 2007
Geriatric oncologyLodovico Balducci
Division of Medical Oncology and Hematology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
Crit Rev Oncol Hematol 46:211-20. 2003..Treatment of cancer with chemotherapy may be associated with increased risk of complications, especially mucositis and neutropenia. The latter may be ameliorated by prophylactic use of growth factors and correction of anemia...
The role of myelopoietic growth factors in managing cancer in the elderlyLodovico Balducci
Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
Drugs 62:47-63. 2002..Such information will lead to better management of cancer in older patients...
Biological basis of cancer in the older personClaudia Beghe
University of South Florida College of Medicine, Tampa, Florida, USA
Cancer Treat Res 124:189-221. 2005
[Medical and social involvements of the cancer in the elderly]Lodovico Balducci
d oncologie à l Université de Floride, College of Medicine, en charge du programme d oncogériatrie au H Lee Moffitt Cancer Center Research Institute, Tampa, FL 33612, Etats Unis
Med Sci (Paris) 23:35-7. 2007..The conclusion targets the importance of the functional age of the patients and the presence of natural helping, on which the authorities should rule. double dagger...
Epidemiology of cancer and agingLodovico Balducci
Senior Adult Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
J Oncol Manag 14:47-50. 2005..On the basis of these findings, preventative and therapeutic strategies for the elderly may be formulated...
Epidemiology of cancer and agingLodovico Balducci
Senior Adult Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
Cancer Treat Res 124:1-15. 2005
Cancer and ageing: a nexus at several levelsLodovico Balducci
Senior Oncology Program, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA
Nat Rev Cancer 5:655-62. 2005....
New paradigms for treating elderly patients with cancer: the comprehensive geriatric assessment and guidelines for supportive careLodovico Balducci
Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 9416, USA
J Support Oncol 1:30-7. 2003..The development of effective strategies for the management of toxicity caused by anticancer drugs may help the elderly, as much as younger patients, expect and look forward to a positive outcome with their treatment...
Molecular insight in cancer treatment and preventionLodovico Balducci
Interdisciplinary Oncology, University of South Florida College of Medicine, H Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
Int J Biochem Cell Biol 39:1329-36. 2007....
Anemia, cancer, and agingLodovico Balducci
Senior Adult Oncology Program, H Lee Moffitt Cancer Center Research Institute, Tampa, FL 33612, USA
Cancer Control 10:478-86. 2003..Anemia is an issue of concern in the management of older patients with cancer. In this age group, the incidence and prevalence of both cancer and anemia increase with age...
Prevention of cancer in the older personLodovico Balducci
Interdisciplinary Oncology Program, University of South Florida College of Medicine, University of South Florida, Adult Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Clin Geriatr Med 18:505-28. 2002..No definite recommendation may be issued at present related to screening for prostate, lung, and cervical cancer. Ongoing clinical trials may answer some of these questions...
The elderly patient with cancer: new approaches for improved outcomesLodovico Balducci
Senior Adult Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9416, USA
J Support Oncol 1:3-4. 2003
Cancer cachexia: traditional therapies and novel molecular mechanism-based approaches to treatmentNagi B Kumar
Department of Population Sciences, H Lee Moffitt Cancer Center and Research Institute at the University of South Florida College of Medicine, 12902 Magnolia Drive, Tampa, FL 33612, USA
Curr Treat Options Oncol 11:107-17. 2010....
Treatment tolerance and efficacy in geriatric oncology: a systematic review of phase III randomized trials conducted by five National Cancer Institute-sponsored cooperative groupsAmbuj Kumar
H Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, FL 33612, USA
J Clin Oncol 25:1272-6. 2007..A systematic review to assess the accurate participation of elderly patients in RCTs has not been performed...
Can older cancer patients tolerate chemotherapy? A prospective pilot studyHongbin Chen
Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, Florida 33612, USA
Cancer 97:1107-14. 2003..This prospective pilot study evaluated the changes in functional, mental, nutritional, and comorbid status, as well as the quality of life (QOL), in geriatric oncology patients receiving chemotherapy...
