Khaldoun Almhanna

Summary

Affiliation: H. Lee Moffitt Cancer Center and Research Institute
Country: USA

Publications

  1. ncbi Targeting the human epidermal growth factor receptor 2 in esophageal cancer
    Khaldoun Almhanna
    Gastrointestinal Tumor Program, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Cancer Control 20:111-6. 2013
  2. pmc Association between COX-2 expression and effectiveness of COX-2 inhibitors in a phase II trial in patients with metastatic colorectal adenocarcinoma
    Khaldoun Almhanna
    Department of Gastrointestinal Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Anticancer Res 32:3559-63. 2012
  3. ncbi Neoadjuvant or adjuvant therapy for resectable esophageal cancer: is there a standard of care?
    Khaldoun Almhanna
    Gastrointestinal Tumor Program, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Cancer Control 20:89-96. 2013
  4. doi Lymph node harvest in esophageal cancer after neoadjuvant chemoradiotherapy
    Ravi Shridhar
    Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA
    Ann Surg Oncol 20:3038-43. 2013
  5. doi Outcomes associated with surgery for T4 esophageal cancer
    Jose M Pimiento
    Program of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, USA
    Ann Surg Oncol 20:2706-12. 2013
  6. doi Extent of lymphadenectomy does not predict survival in patients treated with primary esophagectomy
    Joyce Wong
    Department of Gastrointestinal Surgery, H Lee Moffitt Cancer Center, Tampa, FL, USA
    J Gastrointest Surg 17:1562-8; discussion 1569. 2013
  7. ncbi Adjuvant radiation therapy and lymphadenectomy in esophageal cancer: a SEER database analysis
    Ravi Shridhar
    Department of Radiation Oncology, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    J Gastrointest Surg 17:1339-45. 2013
  8. doi Body mass index and survival in esophageal adenocarcinoma treated with chemoradiotherapy followed by esophagectomy
    Ravi Shridhar
    Department of Radiation Oncology, H Lee Moffitt Cancer Center, 12902 Magnolia Dr, Tampa, FL 33612, USA
    J Gastrointest Surg 16:1296-302. 2012
  9. ncbi The impact of body mass index on esophageal cancer
    Joyce Y Wong
    Surgical Oncology Fellowship Program, H Lee Moffitt Cancer Center, Tampa 33612, FL, USA
    Cancer Control 20:138-43. 2013
  10. doi Increased survival associated with surgery and radiation therapy in metastatic gastric cancer: a Surveillance, Epidemiology, and End Results database analysis
    Ravi Shridhar
    Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Cancer 119:1636-42. 2013

Collaborators

Detail Information

Publications20

  1. ncbi Targeting the human epidermal growth factor receptor 2 in esophageal cancer
    Khaldoun Almhanna
    Gastrointestinal Tumor Program, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Cancer Control 20:111-6. 2013
    ..In addition to presenting data on the HER2 cascade, the authors review clinical trials performed to date and also present the validated standard scoring system for HER2 overexpression in esophageal cancer...
  2. pmc Association between COX-2 expression and effectiveness of COX-2 inhibitors in a phase II trial in patients with metastatic colorectal adenocarcinoma
    Khaldoun Almhanna
    Department of Gastrointestinal Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Anticancer Res 32:3559-63. 2012
    ..We evaluated the COX-2 expression in the available tumors from enrolled patients by immunohistochemistry, as well as its correlation with clinical outcome...
  3. ncbi Neoadjuvant or adjuvant therapy for resectable esophageal cancer: is there a standard of care?
    Khaldoun Almhanna
    Gastrointestinal Tumor Program, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    Cancer Control 20:89-96. 2013
    ....
  4. doi Lymph node harvest in esophageal cancer after neoadjuvant chemoradiotherapy
    Ravi Shridhar
    Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA
    Ann Surg Oncol 20:3038-43. 2013
    ..This study was designed to determine the effects of lymph node (LN) harvest on survival in esophageal cancer after neoadjuvant chemoradiation (nCRT)...
  5. doi Outcomes associated with surgery for T4 esophageal cancer
    Jose M Pimiento
    Program of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, USA
    Ann Surg Oncol 20:2706-12. 2013
    ..T4 esophageal cancer often portends a dismal prognosis even after surgical resection. Historical incomplete resections and poor survival rates often make surgery palliative rather than curative...
  6. doi Extent of lymphadenectomy does not predict survival in patients treated with primary esophagectomy
    Joyce Wong
    Department of Gastrointestinal Surgery, H Lee Moffitt Cancer Center, Tampa, FL, USA
    J Gastrointest Surg 17:1562-8; discussion 1569. 2013
    ..Current guidelines recommend extended lymphadenectomy in patients not receiving neoadjuvant therapy. We reviewed our single institutional experience with nodal harvest for esophageal cancer in a non-neoadjuvant therapy setting...
  7. ncbi Adjuvant radiation therapy and lymphadenectomy in esophageal cancer: a SEER database analysis
    Ravi Shridhar
    Department of Radiation Oncology, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
    J Gastrointest Surg 17:1339-45. 2013
    ..This study seeks to determine the effects of postoperative radiation therapy and lymphadenectomy on survival in esophageal cancer...
  8. doi Body mass index and survival in esophageal adenocarcinoma treated with chemoradiotherapy followed by esophagectomy
    Ravi Shridhar
    Department of Radiation Oncology, H Lee Moffitt Cancer Center, 12902 Magnolia Dr, Tampa, FL 33612, USA
    J Gastrointest Surg 16:1296-302. 2012
    ..Body mass index (BMI) has been linked with inferior outcomes in gastrointestinal malignancies. The purpose of this study is to evaluate the effect of BMI on survival in patients with esophageal adenocarcinoma...
  9. ncbi The impact of body mass index on esophageal cancer
    Joyce Y Wong
    Surgical Oncology Fellowship Program, H Lee Moffitt Cancer Center, Tampa 33612, FL, USA
    Cancer Control 20:138-43. 2013
    ..Surgeons are increasingly operating on patients who are overweight or obese. The influence of obesity on surgical and oncologic outcomes has only recently been addressed. We focus this review on obesity and its impact on esophageal cancer...
  10. doi Increased survival associated with surgery and radiation therapy in metastatic gastric cancer: a Surveillance, Epidemiology, and End Results database analysis
    Ravi Shridhar
    Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida 33612, USA
    Cancer 119:1636-42. 2013
    ..Patients with metastatic gastric cancer have poor survival. The purpose of this study was to compare outcomes of metastatic gastric cancer patients stratified by surgery and radiation therapy...
  11. doi Effect of body mass index in patients undergoing resection for gastric cancer: a single center US experience
    Joyce Wong
    Department of Gastrointestinal Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    J Gastrointest Surg 18:505-11. 2014
    ..With rising obesity in the USA, the impact of body mass index (BMI) on survival in gastric cancer remains unclear...
  12. ncbi Radiation therapy and esophageal cancer
    Ravi Shridhar
    Radiation Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Control 20:97-110. 2013
    ..Although the incidence of squamous cell carcinoma has declined, the incidence of adenocarcinoma has risen due to increases in obesity and gastroesophageal reflux disease...
  13. ncbi Defining the learning curve for robotic-assisted esophagogastrectomy
    Jonathan M Hernandez
    Department of Surgery, University of South Florida, Tampa, FL, USA
    J Gastrointest Surg 17:1346-51. 2013
    ..The purpose of this study is to define the learning curve for robotic-assisted esophagogastrectomy with respect to operative time, conversion rates, and patient safety...
  14. doi Pathologic nonresponders after neoadjuvant chemoradiation for esophageal cancer demonstrate no survival benefit compared with patients treated with primary esophagectomy
    George W Dittrick
    Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, USA
    Ann Surg Oncol 19:1678-84. 2012
    ..This study was designed to evaluate survival in pNR to NCRT compared with patients treated with primary esophagectomy (PE)...
  15. ncbi Endoscopic therapy of neoplasia related to Barrett's esophagus and endoscopic palliation of esophageal cancer
    Shivakumar Vignesh
    Section of Endoscopic Oncology, Gastrointestinal Tumor Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Control 20:117-29. 2013
    ..Barrett's esophagus (BE) is the most important identifiable risk factor for the progression to esophageal adenocarcinoma...
  16. pmc Multimodality approach for locally advanced esophageal cancer
    Khaldoun Almhanna
    Department of Gastrointestinal Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States
    World J Gastroenterol 18:5679-87. 2012
    ..The role of adjuvant chemotherapy following curative resection is still unclear. External beam radiation therapy alone is considered palliative and is typically reserved for patients with a poor performance status...
  17. doi Stability of endoscopic ultrasound-guided fiducial marker placement for esophageal cancer target delineation and image-guided radiation therapy
    Daniel C Fernandez
    Department of Radiation Oncology, H Lee Moffitt Cancer Center, Tampa, Florida Electronic address
    Pract Radiat Oncol 3:32-9. 2013
    ..In this study, we report on the stability of endoscopic ultrasound (EUS)-guided fiducial placement for esophageal cancers and utilization for radiation treatment planning and IGRT...
  18. doi Prognostic impact of lymph node retrieval and ratio in gastric cancer: a U.S. single center experience
    Joyce Wong
    Department of Gastrointestinal Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA
    J Gastrointest Surg 17:2059-66. 2013
    ..Increased lymph node (LN) retrieval for gastric cancer has been associated with improved overall survival (OS). This study examines the impact of number of examined LN (eLN) and lymph node ratio...
  19. ncbi Targeted therapy for gastric adenocarcinoma
    Khaldoun Almhanna
    Department of Gastrointestinal Oncology, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Adv Pharmacol 65:437-70. 2012
    ..We have reviewed the different pathways relevant to gastric cancer development with focus on the recent advances in targeting these pathways in order to improve outcomes in this disease...
  20. doi A phase II study of RO4929097 in metastatic colorectal cancer
    Jonathan R Strosberg
    Dept of GI Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States
    Eur J Cancer 48:997-1003. 2012
    ..RO4929097 is a selective inhibitor of γ-secretase. We tested the activity of RO4929097 in patients with metastatic, refractory colorectal cancer...