Thomas J Guzzo

Summary

Country: USA

Publications

  1. ncbi Impact of multiple biopsy cores on predicting final tumor volume in prostate cancer detected by a single microscopic focus of cancer on biopsy
    Thomas J Guzzo
    Department of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 66:361-5. 2005
  2. ncbi Defining pathological variables to predict biochemical failure in patients with positive surgical margins at radical prostatectomy: implications for adjuvant radiotherapy
    Matthew J Resnick
    Department of Surgery, Division of Urology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    BJU Int 105:1377-80. 2010
  3. doi Bladder cancer patterns of pelvic failure: implications for adjuvant radiation therapy
    Brian C Baumann
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Int J Radiat Oncol Biol Phys 85:363-9. 2013
  4. doi A novel risk stratification to predict local-regional failures in urothelial carcinoma of the bladder after radical cystectomy
    Brian C Baumann
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Int J Radiat Oncol Biol Phys 85:81-8. 2013
  5. ncbi Percutaneous computed tomography-guided renal mass radiofrequency ablation versus cryoablation: doses of sedation medication used
    Carl M Truesdale
    Division of Interventional Radiology, Perelman School of Medicine at the University of Pennsylvania, Hospital of University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Vasc Interv Radiol 24:347-50. 2013
  6. doi Endorectal T2-weighted MRI does not differentiate between favorable and adverse pathologic features in men with prostate cancer who would qualify for active surveillance
    Thomas J Guzzo
    Department of Surgery, Division of Urology, The Hospital of University of Pennsylvania, Philadelphia, PA, USA
    Urol Oncol 30:301-5. 2012
  7. doi Upfront androgen deprivation therapy with salvage radiation may improve biochemical outcomes in prostate cancer patients with post-prostatectomy rising PSA
    Joanne W Jang
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 83:1493-9. 2012
  8. ncbi Impact of adjuvant chemotherapy on patients with lymph node metastasis at the time of radical cystectomy
    Thomas J Guzzo
    Department of Surgery, Division of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Can J Urol 17:5465-71. 2010
  9. doi Hydronephrosis is an independent predictor of poor clinical outcome in patients treated for muscle-invasive transitional cell carcinoma with radical cystectomy
    Daniel Canter
    Department of Surgery, Division of Urology, The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 72:379-83. 2008
  10. ncbi Minimal tumor volume may provide additional prognostic information in good performance patients after radical prostatectomy
    Thomas J Guzzo
    Department of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 69:1147-51. 2007

Detail Information

Publications34

  1. ncbi Impact of multiple biopsy cores on predicting final tumor volume in prostate cancer detected by a single microscopic focus of cancer on biopsy
    Thomas J Guzzo
    Department of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 66:361-5. 2005
    ..Discordance has been noted between transrectal ultrasound-guided biopsy results and tumor volume even when minimal amounts of tumor are found on biopsy...
  2. ncbi Defining pathological variables to predict biochemical failure in patients with positive surgical margins at radical prostatectomy: implications for adjuvant radiotherapy
    Matthew J Resnick
    Department of Surgery, Division of Urology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    BJU Int 105:1377-80. 2010
    ....
  3. doi Bladder cancer patterns of pelvic failure: implications for adjuvant radiation therapy
    Brian C Baumann
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Int J Radiat Oncol Biol Phys 85:363-9. 2013
    ..Modern RT techniques with improved normal tissue sparing have rekindled interest but require knowledge of pelvic failure patterns to design treatment volumes...
  4. doi A novel risk stratification to predict local-regional failures in urothelial carcinoma of the bladder after radical cystectomy
    Brian C Baumann
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Int J Radiat Oncol Biol Phys 85:81-8. 2013
    ..Modern techniques with improved normal tissue sparing have rekindled interest in RT. We assessed the risk of LF and determined those factors that predict recurrence to facilitate patient selection for future adjuvant RT trials...
  5. ncbi Percutaneous computed tomography-guided renal mass radiofrequency ablation versus cryoablation: doses of sedation medication used
    Carl M Truesdale
    Division of Interventional Radiology, Perelman School of Medicine at the University of Pennsylvania, Hospital of University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Vasc Interv Radiol 24:347-50. 2013
    ..To compare the amount of sedation medication administered during radiofrequency (RF) ablation versus cryoablation of small renal masses...
  6. doi Endorectal T2-weighted MRI does not differentiate between favorable and adverse pathologic features in men with prostate cancer who would qualify for active surveillance
    Thomas J Guzzo
    Department of Surgery, Division of Urology, The Hospital of University of Pennsylvania, Philadelphia, PA, USA
    Urol Oncol 30:301-5. 2012
    ..The goal of our study was to evaluate the ability of endorectal MRI (eMRI) to predict adverse pathologic features in patients who would otherwise qualify for an AS program...
  7. doi Upfront androgen deprivation therapy with salvage radiation may improve biochemical outcomes in prostate cancer patients with post-prostatectomy rising PSA
    Joanne W Jang
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 83:1493-9. 2012
    ..However, the benefit of ADT with salvage RT in post-prostatectomy patients is not clearly established. Our study compares biochemical outcomes in post-prostatectomy patients who received salvage RT with or without concurrent ADT...
  8. ncbi Impact of adjuvant chemotherapy on patients with lymph node metastasis at the time of radical cystectomy
    Thomas J Guzzo
    Department of Surgery, Division of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Can J Urol 17:5465-71. 2010
    ..We set out to determine the impact of adjuvant cisplatin-based chemotherapy (AC) in a cohort of lymph node positive patients following RC...
  9. doi Hydronephrosis is an independent predictor of poor clinical outcome in patients treated for muscle-invasive transitional cell carcinoma with radical cystectomy
    Daniel Canter
    Department of Surgery, Division of Urology, The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 72:379-83. 2008
    ..The purpose of this study was to assess the prognostic significance of hydronephrosis on pathologic and clinical outcomes in muscle-invasive bladder cancer...
  10. ncbi Minimal tumor volume may provide additional prognostic information in good performance patients after radical prostatectomy
    Thomas J Guzzo
    Department of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 69:1147-51. 2007
    ..We evaluated the prognostic value of an estimated TV in patients undergoing RP in predicting for prostate-specific antigen (PSA) failure...
  11. doi Repeat prostate biopsy and the incremental risk of clinically insignificant prostate cancer
    Matthew J Resnick
    Division of Urology, Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Urology 77:548-52. 2011
    ..To determine the incremental risk of diagnosis of clinically insignificant prostate cancer with serial prostate biopsies...
  12. ncbi Preoperative parameters, including percent positive biopsy, in predicting seminal vesicle involvement in patients with prostate cancer
    Thomas J Guzzo
    Department of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Urol 175:518-21; discussion 521-2. 2006
    ..Therefore we evaluated the clinical parameters associated with a positive SV finding on final pathology and identified those patients with a minimal risk of SV involvement for potential SV sparing surgery...
  13. ncbi A thorough pelvic lymph node dissection in presence of positive margins associated with better clinical outcomes in radical cystectomy patients
    Daniel Canter
    Department of Surgery, Division of Urology, Hospital of University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 74:161-5. 2009
    ..To evaluate the effect of positive surgical margins in patients with muscle-invasive transitional cell carcinoma of the bladder on survival...
  14. doi Bladder preservation in the treatment of muscle-invasive bladder cancer (MIBC): a review of the literature and a practical approach to therapy
    Zachary L Smith
    Division of Urology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    BJU Int 112:13-25. 2013
    ..We present a comprehensive review of the literature and outline a practical approach to bladder preservation therapy for MIBC...
  15. doi Increased EZH2 protein expression is associated with invasive urothelial carcinoma of the bladder
    Hang Wang
    Department of Urology, James Buchanan Brady Urological Institute, Baltimore, MD 21287, USA
    Urol Oncol 30:428-33. 2012
    ..We examined EZH2 protein expression levels in bladder tissue specimens from patients with urothelial carcinoma (UC) and investigated the relationship between EZH2 protein expression and clinical outcomes...
  16. doi Is ultrasound imaging inferior to computed tomography or magnetic resonance imaging in evaluating renal mass size?
    Phillip Mucksavage
    Department of Urology, University of California, Irvine, School of Medicine, Orange, California 92868, USA
    Urology 79:28-31. 2012
    ..To evaluate whether ultrasonography was inferior in detecting the size of a renal mass preoperatively because of the increased attention on the harmful effects of ionizing radiation in medical imaging...
  17. doi Longitudinal evaluation of the concordance and prognostic value of lymphovascular invasion in transurethral resection and radical cystectomy specimens
    Matthew J Resnick
    Division of Urology and Department of Pathology University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    BJU Int 107:46-52. 2011
    ..Additionally, to evaluate the prognostic value of LVI in the prediction of lymph node metastases, overall survival, disease-specific survival and recurrence-free survival following RC...
  18. doi Relationship of biochemical outcome to percentage of positive biopsies in men with clinically localized prostate cancer treated with permanent interstitial brachytherapy
    Thomas J Guzzo
    Department of Urology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Urology 71:723-7. 2008
    ..We conducted an analysis to determine the clinical utility of the PPBs in predicting BF after permanent interstitial brachytherapy for patients with clinically localized prostate cancer...
  19. doi A case of synchronous bilateral testicular seminoma
    Matthew J Resnick
    Division of Urology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    Nat Clin Pract Urol 5:397-401. 2008
    ..A previously healthy 51-year-old man with two children sustained a minor testicular trauma and subsequently sought medical care for persistent discomfort...
  20. pmc Variation in use of androgen suppression with external-beam radiotherapy for nonmetastatic prostate cancer
    Samuel Swisher-McClure
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 83:8-15. 2012
    ..To describe practice patterns associated with androgen suppression (AS) stratified by disease risk group in patients undergoing external-beam radiotherapy (EBRT) for localized prostate cancer...
  21. doi Tumor enucleation for small renal masses
    Nicholas A Laryngakis
    Division of Urology, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Curr Opin Urol 22:365-71. 2012
    ..Traditionally, the treatment of suspicious renal masses was radical nephrectomy. However, nephron-sparing surgery is the standard of care, when possible, because of the risk of renal insufficiency associated with radical nephrectomy...
  22. doi Enucleation of renal cell carcinoma with ablation of the tumour base
    Alexander Kutikov
    Department of Surgery, Division of Urology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    BJU Int 102:688-91. 2008
    ....
  23. ncbi Clinical approach to the prostate: an update
    Alexander Kutikov
    Division of Urology, Department of Surgery, University of Pennsylvania Medical Center, 9 Penn Tower, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Radiol Clin North Am 44:649-63, vii. 2006
    ..Current treatment regimens for prostatitis remain ineffective at best. Contemporary approaches to the pathogenesis, diagnosis, and treatment of benign prostatic hyperplasia, prostate cancer, and prostatitis are discussed in this review...
  24. doi Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo
    Trinity J Bivalacqua
    Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Urology 72:1169-73. 2008
    ..To evaluate the effect of the fibrin sealant, Evicel, on the neuroregulatory control of penile erections in an experimental rat model...
  25. doi Tumor enucleation: a safe treatment alternative for renal cell carcinoma
    Nicholas A Laryngakis
    Division of Urology, Department of Surgery, Hospital of University of Pennsylvania, Philadelphia, PA, USA
    Expert Rev Anticancer Ther 11:893-9. 2011
    ..Current data suggest that tumor enucleation is a safe alternative for small renal masses that are locally confined on preoperative imaging, easily delineated intraoperatively and do not appear to grossly invade beyond the pseudocapsule...
  26. ncbi Re-examination of the natural history of high-grade T1 bladder cancer using a large contemporary cohort
    Daniel J Canter
    Department of Urology, Einstein Healthcare Network and Urologic Institute of Southeastern Pennsylvania, PA, USA
    Int Braz J Urol 40:172-8. 2014
    ..Using two non-muscle invasive bladder cancer (NMIBC) databases, we re-examined the rate of progression of HG T1 bladder cancer in our bladder cancer populations...
  27. doi Impact on renal function of percutaneous thermal ablation of renal masses in patients with preexisting chronic kidney disease
    Eric Wehrenberg-Klee
    Department of Radiology, Division of Interventional Radiology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    J Vasc Interv Radiol 23:41-5. 2012
    ..To examine the effect of percutaneous thermal ablation of renal masses on renal function among patients with baseline chronic kidney disease (CKD)...
  28. doi Smoking knowledge assessment and cessation trends in patients with bladder cancer presenting to a tertiary referral center
    Thomas J Guzzo
    Department of Urology, University of Pennsylvania School of Medicine, Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania 19104, USA
    Urology 79:166-71. 2012
    ..However, little information is available regarding patients' knowledge of the risks of smoking and the role of their urologists in initiating smoking cessation at diagnosis...
  29. ncbi Modern management of pheochromocytoma
    Sanjay Kasturi
    Division of Urology, Department of Surgery, University of Pennsylvania Medical Center, 9 Penn Tower, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Nat Clin Pract Urol 4:630-3. 2007
    ..A 55-year-old male with poorly controlled hypertension and a history of coronary artery disease presented with a large adrenal mass. The patient also reported a long-standing history of profuse sweating, tinnitus, vomiting and headaches...
  30. ncbi Urethral carcinosarcoma from bladder carcinosarcomatous lesions: analysis of clinicopathological features
    Trinity J Bivalacqua
    The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Can J Urol 16:4512-5. 2009
    ..The goal of this case report is to review our current understanding of the pathological and recurrence patterns of patients with CS of the urinary bladder in order to better define postoperative care for patients with CS of the bladder...
  31. doi Robotic surgical training of the urologic oncologist
    Thomas J Guzzo
    Department of Urology, The James Buchanan Brady Urologic Institute, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Urol Oncol 27:214-7. 2009
    ..We review the current literature regarding robotic surgical training, highlight potentially effective training strategies, and discuss future improvements in robotic surgical training of the urologic oncologist...
  32. ncbi Initial experience with laparoscopic transvesical ureteral reimplantation at the Children's Hospital of Philadelphia
    Alexander Kutikov
    Department of Surgery, Division of Urology, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Urol 176:2222-5; discussion 2225-6. 2006
    ..Laparoscopic transvesical ureteral reimplantation with or without robotic assisted surgical devices is being developed as an alternative to open surgery. We review our experience with laparoscopic transvesical ureteral reimplantation...
  33. doi Re: Guzzo TJ, Vira MA, Neway W, et al: Minimal tumor volume may provide additional prognostic information in good performance patients after radical prostatectomy. Urology 69: 1147-1151, 2007
    Thomas J Guzzo
    Urology 71:1230-1. 2008
  34. ncbi The clinical and pathological history of prostate cancer progression in men with a prior history of high grade prostatic intraepithelial neoplasia
    Thomas J Guzzo
    The James Buchanan Brady Urologic Institute, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Can J Urol 15:4174-8; discussion 4179. 2008
    ..Our objective was to evaluate the natural history of HGPIN to better assess the time frame to disease progression and the pathological findings at the time of progression to cancer...