K J Harjai

Summary

Affiliation: Guthrie Research Institute
Country: USA

Publications

  1. doi request reprint Developing a new hybrid revascularization program: a road map for hospital managers and physician leaders
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania 18840, USA
    J Interv Cardiol 25:557-64. 2012
  2. doi request reprint Early readmissions after percutaneous coronary intervention in a rural tertiary care center (from the Guthrie Health Off-label Stent [GHOST] Registry)
    Kishore J Harjai
    Guthrie Clinic and Robert Packer Hospital, Sayre, PA, USA
    Am J Cardiol 110:491-7. 2012
  3. doi request reprint Long-term safety and effectiveness of drug-eluting stents compared to bare metal stents following successful PCI in non-ST-elevation myocardial infarction: findings from the Guthrie Health Off-Label StenT (GHOST) Registry
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania, USA
    J Interv Cardiol 25:28-36. 2012
  4. ncbi request reprint Usefulness of routine unfractionated heparin infusion following primary percutaneous coronary intervention for acute myocardial infarction in patients not receiving glycoprotein IIb/IIIa inhibitors
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania, USA
    Am J Cardiol 99:202-7. 2007
  5. ncbi request reprint Impact of interventionalist volume, experience, and board certification on coronary angioplasty outcomes in the era of stenting
    Kishore J Harjai
    Cardiac Catheterization Laboratories, Guthrie Clinic, One Guthrie Square, Sayre, PA 18840, USA
    Am J Cardiol 94:421-6. 2004
  6. doi request reprint Comparison of long-term outcomes of bare metal or drug-eluting stent implantation in standard versus off-label coronary narrowings
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania, USA
    Am J Cardiol 103:1537-45. 2009
  7. ncbi request reprint Contemporary management of carotid artery stenosis: no resting places, no plateaus
    Kishore J Harjai
    Guthrie Health System, Sayre, PA 18840, USA
    J Interv Cardiol 19:63-6. 2006
  8. ncbi request reprint Does proximal location of culprit lesion confer worse prognosis in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction?
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania 18840, USA
    J Interv Cardiol 19:285-94. 2006
  9. doi request reprint Clinical outcomes following drug-eluting versus bare metal stent implantation for lesion subsets excluded from pivotal clinical trials: findings from the GHOST Study (Guthrie Health System Off-Label StenT Study)
    Kishore J Harjai
    Guthrie Clinic, One Guthrie Square, Sayre, Pennsylvania 18840, USA
    J Interv Cardiol 21:315-24. 2008
  10. ncbi request reprint Trials and tribulations of carotid artery stenting: The Interventionalists' perspective on SAPPHIRE, EVA-3S, and SPACE Trials
    Kishore J Harjai
    Guthrie Clinic, Sayre, PA 18840, USA
    J Interv Cardiol 20:389-94. 2007

Detail Information

Publications44

  1. doi request reprint Developing a new hybrid revascularization program: a road map for hospital managers and physician leaders
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania 18840, USA
    J Interv Cardiol 25:557-64. 2012
    ..In this article, we describe the people-process-technology issues that managers and leaders are likely to encounter as they develop a hybrid revascularization program in their practice...
  2. doi request reprint Early readmissions after percutaneous coronary intervention in a rural tertiary care center (from the Guthrie Health Off-label Stent [GHOST] Registry)
    Kishore J Harjai
    Guthrie Clinic and Robert Packer Hospital, Sayre, PA, USA
    Am J Cardiol 110:491-7. 2012
    ..2, 95% confidence interval 1.8 to 2.8). In conclusion, readmission within 30 days after PCI is common and frequently related to cardiac causes. Patients who require an ER after PCI have higher 1-year mortality and MACEs...
  3. doi request reprint Long-term safety and effectiveness of drug-eluting stents compared to bare metal stents following successful PCI in non-ST-elevation myocardial infarction: findings from the Guthrie Health Off-Label StenT (GHOST) Registry
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania, USA
    J Interv Cardiol 25:28-36. 2012
    ..The long-term safety and effectiveness of drug-eluting stents (DES) versus bare metal stents (BMS) in non-ST-segment elevation myocardial infarction (NSTEMI) beyond 2 years after percutaneous coronary intervention (PCI) is unknown...
  4. ncbi request reprint Usefulness of routine unfractionated heparin infusion following primary percutaneous coronary intervention for acute myocardial infarction in patients not receiving glycoprotein IIb/IIIa inhibitors
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania, USA
    Am J Cardiol 99:202-7. 2007
    ..However, in a subset of patients treated with PTCA, postprocedural heparin use was independently associated with fewer in-hospital and 1-year MACEs...
  5. ncbi request reprint Impact of interventionalist volume, experience, and board certification on coronary angioplasty outcomes in the era of stenting
    Kishore J Harjai
    Cardiac Catheterization Laboratories, Guthrie Clinic, One Guthrie Square, Sayre, PA 18840, USA
    Am J Cardiol 94:421-6. 2004
    ..Rather, patients' clinical risk score is the overriding determinant of clinical outcomes. Our findings emphasize the power of a well-organized high-volume system to minimize the impact of operator factors on outcomes of PCI...
  6. doi request reprint Comparison of long-term outcomes of bare metal or drug-eluting stent implantation in standard versus off-label coronary narrowings
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania, USA
    Am J Cardiol 103:1537-45. 2009
    ..In conclusion, compared with BMS, use of DES is associated with clinical benefit in standard and off-label lesions at late follow-up. Decrease in elective TVR does not explain the apparent mortality benefit from DES implantation...
  7. ncbi request reprint Contemporary management of carotid artery stenosis: no resting places, no plateaus
    Kishore J Harjai
    Guthrie Health System, Sayre, PA 18840, USA
    J Interv Cardiol 19:63-6. 2006
  8. ncbi request reprint Does proximal location of culprit lesion confer worse prognosis in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction?
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania 18840, USA
    J Interv Cardiol 19:285-94. 2006
    ..In conclusion, proximal location of the culprit lesion is a strong independent predictor of worse in-hospital outcomes in patients with STEMI undergoing primary PCI...
  9. doi request reprint Clinical outcomes following drug-eluting versus bare metal stent implantation for lesion subsets excluded from pivotal clinical trials: findings from the GHOST Study (Guthrie Health System Off-Label StenT Study)
    Kishore J Harjai
    Guthrie Clinic, One Guthrie Square, Sayre, Pennsylvania 18840, USA
    J Interv Cardiol 21:315-24. 2008
    ..We assessed outcomes of patients undergoing drug-eluting stent (DES) vs. bare metal stent (BMS) implantation for complex lesions excluded from pivotal clinical trials of DES...
  10. ncbi request reprint Trials and tribulations of carotid artery stenting: The Interventionalists' perspective on SAPPHIRE, EVA-3S, and SPACE Trials
    Kishore J Harjai
    Guthrie Clinic, Sayre, PA 18840, USA
    J Interv Cardiol 20:389-94. 2007
    ....
  11. doi request reprint A comparison of contemporary definitions of contrast nephropathy in patients undergoing percutaneous coronary intervention and a proposal for a novel nephropathy grading system
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania, USA
    Am J Cardiol 101:812-9. 2008
    ..5 mg/dl consistently predicted adverse events after PCI. By unifying these 2 definitions, we devised a novel nephropathy grading system that is predictive of 6-month MACEs and all-cause mortality after PCI...
  12. doi request reprint Management of multivessel coronary disease: let us not shortchange drug-eluting stents
    Kishore J Harjai
    Cardiac Catheterization Laboratories, Guthrie Clinic, One Guthrie Square, Sayre, PA 18840, USA
    J Interv Cardiol 21:213-7. 2008
    ..Till randomized trial data become available, physicians should continue to use their clinical judgment based on existing evidence in managing their patients with multivessel coronary artery disease (CAD)...
  13. doi request reprint Dual antiplatelet therapy for more than 12 months after percutaneous coronary intervention: insights from the Guthrie PCI Registry
    K J Harjai
    Guthrie Health System, Sayre, Pennsylvania 18840, USA
    Heart 95:1579-86. 2009
    ..To assess the impact of dual antiplatelet (DAP) therapy of >12 months on long-term death and myocardial infarction (MI) after percutaneous coronary intervention (PCI). Design, setting and..
  14. doi request reprint Major adverse noncardiac events after PCI as predictors of long-term mortality
    Kishore Harjai
    Guthrie Clinic, One Guthrie Square, Sayre, PA 18840, USA
    J Interv Cardiol 21:395-402. 2008
    ..MANE, such as post-PCI bleeding and contrast nephropathy, adversely influence survival, but are not recognized as a standard composite of complications. We assessed the feasibility and prognostic utility of deriving a composite of MANE...
  15. doi request reprint Clinical outcomes in patients with the concomitant use of clopidogrel and proton pump inhibitors after percutaneous coronary intervention: an analysis from the Guthrie Health Off-Label Stent (GHOST) investigators
    Kishore J Harjai
    Cardiac and Vascular Center of Excellence, Guthrie Health, 1 Guthrie Sq, Sayre, PA 18840, USA
    Circ Cardiovasc Interv 4:162-70. 2011
    ..We sought to evaluate whether the use of PPIs with clopidogrel was associated with worse clinical outcomes after percutaneous coronary intervention (PCI) compared with the use of clopidogrel alone...
  16. doi request reprint Low-dose versus high-dose aspirin after percutaneous coronary intervention: analysis from the guthrie health off-label StenT (GHOST) registry
    Kishore J Harjai
    Guthrie Clinic, Sayre, Pennsylvania William Beaumont Hospital, Royal Oak, Michigan
    J Interv Cardiol 24:307-14. 2011
    ..The optimal dose of aspirin therapy after percutaneous coronary intervention (PCI) remains unclear. We sought to compare the effectiveness and safety of low and high doses of aspirin in preventing adverse outcomes after PCI...
  17. doi request reprint Hemodynamic support using the Impella 2.5 catheter system during high-risk percutaneous coronary intervention in a patient with severe aortic stenosis
    Kishore J Harjai
    Guthrie Health System, Sayre, Pennsylvania 18840, USA
    J Interv Cardiol 23:66-9. 2010
    ..We describe a case of severe aortic stenosis with an estimated valve area of 0.9 cm(2) and severe ischemic cardiomyopathy in whom the Impella catheter was successfully used for high-risk multivessel percutaneous coronary intervention...
  18. doi request reprint Repair of right carotid artery pseudoaneurysm in a patient with hostile aortic arch through left ventricular approach
    Kishore J Harjai
    Cardiac Catheterization Laboratories, Guthrie Clinic, One Guthrie Square, Sayre, PA 18840, USA
    J Interv Cardiol 21:239-41. 2008
    ..Our case provides proof-of-principle that complex carotid interventions can be performed expediently through a left ventricular approach in patients with hostile aortic arch...
  19. doi request reprint Occurrence, predictors, and outcomes of post-percutaneous coronary intervention thrombocytopenia in an unselected population
    Chetan Shenoy
    From the Guthrie Clinic, Sayre, Pennsylvania, USA
    J Interv Cardiol 22:156-62. 2009
    ..Background: Thrombocytopenia after PCI has been shown to portend worse prognosis in clinical trials. The significance of post-PCI thrombocytopenia has not previously been examined outside the clinical trial setting...
  20. ncbi request reprint Effects of prior beta-blocker therapy on clinical outcomes after primary coronary angioplasty for acute myocardial infarction
    Kishore J Harjai
    William Beaumont Hospital, Royal, Oak, Michigan 48703, USA
    Am J Cardiol 91:655-60. 2003
    ..72; 95% confidence interval 0.47 to 1.08; p = 0.11). Thus, pretreatment with beta blockers has an independent beneficial effect on short-term clinical outcomes in patients undergoing primary angioplasty for acute myocardial infarction...
  21. ncbi request reprint Comparison of effectiveness of primary angioplasty for proximal versus distal right coronary artery culprit lesion during acute myocardial infarction
    Kishore J Harjai
    William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    Am J Cardiol 90:1193-7. 2002
    ..Thus, in patients with acute myocardial infarction referred for primary angioplasty, proximal RCA location of the culprit lesion is associated with excellent clinical outcomes that are similar to nonproximal RCA lesions...
  22. ncbi request reprint Drug-eluting stents vs. coronary-artery bypass grafting
    Kishore J Harjai
    N Engl J Med 358:2642-3; author reply 2643-4. 2008
  23. ncbi request reprint Prediction of one-year mortality among 30-day survivors after primary percutaneous coronary interventions
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 97:817-22. 2006
    ....
  24. ncbi request reprint Percutaneous coronary interventions in octogenarians. glycoprotein IIb/IIIa receptor inhibitors' safety profile
    H Mehrdad Sadeghi
    Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    J Am Coll Cardiol 42:428-32. 2003
    ..This study was designed to evaluate the safety profile of glycoprotein IIb/IIIa receptor inhibitors (GPI) in octogenarians undergoing percutaneous coronary intervention (PCI)...
  25. ncbi request reprint Comparison of coronary stenting versus conventional balloon angioplasty on five-year mortality in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 96:901-6. 2005
    ..These data support the routine use of coronary stenting in most patients undergoing primary PCI, when feasible...
  26. ncbi request reprint Stenting of anomalous left carotid artery using a radial artery approach
    Kishore J Harjai
    Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan
    Catheter Cardiovasc Interv 61:286-8. 2004
    ..A previous attempt at selective cannulation of the left carotid artery was unsuccessful using a transfemoral approach. We performed successful carotid artery angioplasty and stenting using a right radial artery approach...
  27. ncbi request reprint Characteristics of cerebrovascular accidents after percutaneous coronary interventions
    Srinivas Dukkipati
    Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    J Am Coll Cardiol 43:1161-7. 2004
    ..We sought to identify the incidence, predictors, and clinical implications of cerebrovascular accidents (CVAs) after percutaneous coronary interventions (PCIs)...
  28. ncbi request reprint Clinical and angiographic correlates and outcomes of suboptimal coronary flow inpatients with acute myocardial infarction undergoing primary percutaneous coronary intervention
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Michigan, USA
    J Am Coll Cardiol 42:1739-46. 2003
    ..The purpose of this study was to determine the clinical and angiographic correlates and outcomes of patients with suboptimal coronary flow after primary percutaneous coronary interventions (PCI)...
  29. ncbi request reprint The incidence, predictors, and outcomes of early reinfarction after primary angioplasty for acute myocardial infarction
    Steven J Kernis
    Cardiology Division, William Beaumont Hospital, Royal Oak, Michigan, USA
    J Am Coll Cardiol 42:1173-7. 2003
    ..We sought to identify the incidence, predictors, and clinical consequences of one-month reinfarction (RE-MI) in patients undergoing primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI)...
  30. ncbi request reprint Impact of nephropathy after percutaneous coronary intervention and a method for risk stratification
    Beth A Bartholomew
    Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    Am J Cardiol 93:1515-9. 2004
    ..The RCIN risk score was a clinical assessment tool with excellent predictive ability in identifying the larger population at risk for nephropathy in whom preventative strategies are indicated...
  31. ncbi request reprint Frequency, determinants, and clinical implications of residual intracoronary thrombus following primary angioplasty for acute myocardial infarction
    Kishore J Harjai
    William Beaumont Hospital, Royal Oak, Michigan 48703, USA
    Am J Cardiol 92:377-82. 2003
    ..However, differences in outcomes between patients with and without residual thombus are related to baseline clinical differences rather than thrombus per se...
  32. ncbi request reprint Ischemia-driven target vessel revascularization after-primary percutaneous coronary intervention: patients at risk and their outcomes
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Interv Cardiol 18:149-54. 2005
    ..Importantly, our data suggest that no increase in mortality occur, if ITVR is promptly performed to treat recurrent ischemia after primary PCI...
  33. ncbi request reprint Prognostic significance of transient no-reflow during primary percutaneous coronary intervention for ST-elevation acute myocardial infarction
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Michigan, USA
    Am J Cardiol 92:1445-7. 2003
    ..04) and 6-month mortality (3% vs 31%, adjusted odds ratio 5.4, 95% confidence interval 1.01 to 29.0, p=0.0001)...
  34. ncbi request reprint Comparison of outcomes of diabetic and nondiabetic patients undergoing primary angioplasty for acute myocardial infarction
    Kishore J Harjai
    William Beaumont Hospital, Royal Oak, Michigan, USA
    Am J Cardiol 91:1041-5. 2003
    ..We conclude that diabetics with AMI have less favorable baseline characteristics and are less likely to undergo primary PCI than nondiabetics. Despite excellent angiographic results, diabetics had significantly worse 6-month mortality...
  35. ncbi request reprint Does beta-blocker therapy improve clinical outcomes of acute myocardial infarction after successful primary angioplasty?
    Steven J Kernis
    Cardiology Division, William Beaumont Hospital, Royal Oak, Michigan 48331, USA
    J Am Coll Cardiol 43:1773-9. 2004
    ..We sought to determine if beta-blocker therapy improves clinical outcomes of acute myocardial infarction (AMI) after successful primary percutaneous coronary intervention (PCI)...
  36. ncbi request reprint The relationship between left ventricular shape and QT interval dispersion
    Kishore J Harjai
    Ochsner Clinic, New Orleans, Louisiana, USA
    Echocardiography 19:641-4. 2002
    ....
  37. ncbi request reprint Suboptimal inhibition of platelet aggregation following tirofiban bolus in patients undergoing percutaneous coronary intervention for unstable angina pectoris
    Daniel Soffer
    Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    Am J Cardiol 91:872-5. 2003
  38. ncbi request reprint Use of aspirin in conjunction with angiotensin-converting enzyme inhibitors does not worsen long-term survival in heart failure
    Kishore J Harjai
    Department of Cardiology, Ochsner Clinic, New Orleans, USA
    Int J Cardiol 88:207-14. 2003
    ..We explored the effect of combined ACE-I and aspirin therapy compared to ACE-I without aspirin on clinical outcomes in patients with heart failure...
  39. ncbi request reprint Impact of angina class on inhibition of platelet aggregation following clopidogrel loading in patients undergoing coronary intervention: do we need more aggressive dosing regimens in unstable angina?
    Daniel Soffer
    Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    Catheter Cardiovasc Interv 59:21-5. 2003
    ..018). Patients with UA undergoing PCI have a lower IPA following clopidogrel loading with 450 mg. This may indicate the possibility of clopidogrel resistance in such patients...
  40. ncbi request reprint Variation in hospital length of stay in patients with acute myocardial infarction undergoing primary angioplasty and the need to change the diagnostic-related group system
    Beth A Bartholomew
    William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    Am J Cardiol 92:830-3. 2003
    ..Our investigation suggests the need for a multi-tier diagnostic-related group system for patients with acute myocardial infarction treated with percutaneous coronary intervention...
  41. ncbi request reprint Sustained ventricular tachycardia or fibrillation in the cardiac catheterization laboratory among patients receiving primary percutaneous coronary intervention: incidence, predictors, and outcomes
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Michigan, USA
    J Am Coll Cardiol 43:1765-72. 2004
    ....
  42. ncbi request reprint Procedural success versus clinical risk status in determining discharge of patients after primary angioplasty for acute myocardial infarction
    Prabhakara S Heggunje
    William Beaumont Hospital, Royal Oak, Michigan 48073 6769, USA
    J Am Coll Cardiol 44:1400-7. 2004
    ..We evaluated whether patients' clinical status, angioplasty success, or both, should guide discharge after primary angioplasty (i.e., percutaneous coronary intervention [PCI]) for acute myocardial infarction (AMI)...
  43. ncbi request reprint Left ventricular remodeling and systolic deterioration in acute myocardial infarction: findings from the Stent-PAMI Study
    Stephen J Mattichak
    William Beaumont Hospital, Royal Oak, MI 48073, USA
    J Interv Cardiol 18:255-60. 2005
    ..We sought to determine predictors of LVSD by comparing demographic, procedural, angiographic variables, and 6-month major adverse cardiac events (MACE) in patients with and without LVSD after MI...
  44. ncbi request reprint Does racial bias exist in the medical management of heart failure?
    Kishore J Harjai
    Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana, USA
    Clin Cardiol 25:479-83. 2002
    ..It is suspected that effective therapies are often underutilized in black compared with white patients with coronary artery disease (CAD)...