G E Simon

..Data from a population-based survey were linked to electronic medical records to examine agreement between patients' recalled treatment response and depression severity scores in the medical records...

..Efforts to increase the effectiveness of psychotherapy may required different strategies in group- and network-model practice...

..The authors compared outcomes reported by patients who did or did not return for treatment after an initial psychotherapy visit...

..We followed 982 clinically depressed persons to determine which measures changed and whether the change was synchronous with change in depressive symptoms...

..To evaluate demographic and clinical predictors of suicide attempt and suicide death in a population-based sample of people treated for bipolar disorder (BD)...

..Clinicians have questioned the validity of depression criteria in patients with chronic medical illness, but few empirical data address this question...

..The authors used population-based data to evaluate the risk of suicide death and serious suicide attempt in relation to initiation of antidepressant treatment...

..Epidemiologic data suggest an association between obesity and depression, but findings vary across studies and suggest a stronger relationship in women than men...

..The objective of this study was to examine the indications for benzodiazepine use, and the baseline characteristics, duration of use and clinical outcomes of older primary care patients prescribed benzodiazepines...

..We also discuss how economic incentives are likely to influence selection of research questions, especially research related to drug-gene interactions and to identifying new indications for existing drugs...

..The aim of this study was to assess the relative contributions of diabetes complications, depression and comorbid medical disorders to health service costs in adults with diabetes...

..This trial evaluated the effectiveness of a multi-component care management program in a population-based sample of people with bipolar disorder...

..We examine how clinical and functional outcomes of depression treatment compare in primary-care patients with and without chronic medical illness...

..Despite the availability of efficacious treatments, the long-term course of bipolar disorder is often unfavorable...

..The purpose of the study was to evaluate the prevalence and predictors of depression treatment in a diverse cross-national sample of primary care patients...

..Both antidepressant medication and structured psychotherapy have been proven efficacious, but less than one third of people with depressive disorders receive effective levels of either treatment...

..Among those seeking CAM care for mental disorders, concomitant treatment by conventional medical providers is common, but communication or coordination of care is rare...

..To examine the association between outcome of acute-phase depression treatment and subsequent health services costs...

..This study evaluated the effectiveness of a structured telephone-based care management program for patients in a prepaid health plan receiving new antidepressant prescriptions from psychiatrists...

..Depression co-occurring with diabetes mellitus is associated with higher health services costs, suggesting that more effective depression treatment might reduce use of other medical services...

..Both obesity and depression have been associated with significant increases in health care costs. Previous research has not examined whether cost increases associated with obesity could be explained by confounding effects of depression...

..A pilot study evaluated whether the addition of online coaching from a peer specialist increased participation in an online program featuring educational and interactive modules to promote self-management of bipolar disorder...

..Telephone care management programs can address these gaps, but reliance on live contact makes such programs less available, less timely, and more expensive...

..To examine the association between improvement in depression and loss of weight among women with depressive symptoms entering a behavioral weight loss program...

..Response to specific depression treatments varies widely among individuals. Understanding and predicting that variation could have great benefits for people living with depression...

..Data from a managed care health system were used to examine demographic, clinical, and health system predictors of early dropout from psychotherapy for depression...

..Effectiveness of organized depression care programs is well established, but dissemination will depend on the balance of benefits and costs...

..This study examined how consumer satisfaction ratings differ between mental health care providers to determine whether comparison of ratings is biased by differences in survey response rates or consumer characteristics...

..To evaluate the relationship between mood symptoms and work productivity in people with bipolar disorder...

..Evaluate the association between obesity and depression among middle-aged women...

..Little research has examined the accuracy of recall for mood symptoms using retrospective timelines or life charts. We examined accuracy of recall for mania symptoms over a period of 3 months...

..To examine the relationship between changes in mood symptoms and changes in functioning or disability in people treated for bipolar disorder...

..This study compared the time patterns of suicide attempts among outpatients starting depression treatment with medication or psychotherapy...

..This study evaluated the effects of prenatal antidepressant exposure on perinatal outcomes, congenital malformations, and early growth and development...

..The prevalence, burden, and management of insomnia among primary care patients were evaluated...

..Hypochondriasis is moderately stable over time. The clear distinction between hypochondriasis and anxiety/depressive disorders suggested by ICD-10 and DSM-IV may be difficult to accomplish in practice...

..This study compares baseline characteristics, process of care, and outcomes for managed care patients who received new antidepressant prescriptions from psychiatrists and primary care physicians...

..Randomized effectiveness trials are needed before we can conclude definitively that depression treatment results in productivity improvements sufficient to offset direct treatment costs...

..These findings support earlier studies suggesting that the use of fluoxetine as a first-line antidepressant in primary care will increase antidepressant drug costs, but will not significantly increase total treatment costs...

..We examine the incremental cost-effectiveness of an organized depression management program for high utilizers of medical care...

..This article is a discussion of the use of large clinical databases in population-based research on psychiatric disorders...

..To test the effectiveness of two programmes to improve the treatment of acute depression in primary care...

..Of the patients in the original sample, 5447 underwent a structured assessment of depressive and somatoform disorders...

..Psychiatric and health services research literature was reviewed to identify recent studies regarding effectiveness, cost-effectiveness, and generalizability of collaborative care programs to improve treatment of mood disorders...

..The study examined health care utilization and costs among patients treated for bipolar-spectrum disorders in an insured population...

..To compare the long-term clinical, quality-of-life, and economic outcomes after an initial prescription for fluoxetine, imipramine hydrochloride, or desipramine hydrochloride...

..The authors evaluated the incremental cost-effectiveness of stepped collaborative care for patients with persistent depressive symptoms after usual primary care management...

..Evaluate the incremental cost-effectiveness of a depression relapse prevention program in primary care...

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..This report describes the design and implementation of a randomized trial evaluating a systematic program to improve quality and continuity of care for bipolar disorder...

..To assess effects of stepped collaborative care depression intervention on disability...

..The authors' goal was to determine whether improved outcomes from enhanced acute-phase (3-month) treatment for depression in primary care persisted...

..Cross-national differences in the onset and outcome of depression may reflect either true prevalence differences or differences in diagnostic threshold...

..Centers for Disease Control criteria for CFS did not select a subset of chronic fatigue patients who could be differentiated on disability or psychosocial parameters from patients with chronic fatigue who did not meet CDC criteria...

..Efforts to increase the intensity of depression treatment in primary care should focus on the subgroup of patients who fail to respond to initial treatment...

..To assess the effect of physician training on management of depression...

..This suggests that more systematic and effective depression treatment programmes might have an important effect on long-term course and reduce the overall burden of chronic and recurrent depression...

..We examined whether depression severity, comorbid psychiatric illness, and personality factors might play a role in this lack of response...

..Many clinical and logistical barriers exist in the primary care model for treating adult depression...

..We hypothesized that a relapse prevention intervention would improve adherence to antidepressant medication and improve depression outcomes in high-risk patients compared with usual primary care...

..Despite improvements in the accuracy of diagnosing depression and use of medications with fewer side effects, many patients treated with antidepressant medications by primary care physicians have persistent symptoms...

..Improvements in self-efficacy and several self-management behaviours that were targets of the intervention were significantly related to improvements in depression outcome...

..We apply these concepts to the organization of services for patients with major depression...

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..These population-based methods to improve care of chronic illness require reorganizing the roles of specialists, primary care physicians, and nurses...

..To examine whether depressive symptoms in older adults contribute to increased cost of general medical services...

..We must recall, however, that economic benefits of treatment for mood disorders are secondary to the principal objective of relieving human suffering...

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..Organized depression care programs significantly improve treatment quality, but employer purchasers have been slow to adopt these programs based on lack of evidence for cost-effectiveness from their perspective...

..To present findings from an expert panel-informed literature review on community-based treatment of late-life depression...

..Depressive and manic symptoms were positively, not inversely, correlated, and their co-occurrence was associated with worse quality of life. Implications for the DSM and ICD nosological systems are discussed...

..We sought to determine whether relationship style in patients with diabetes receiving depression treatment is associated with differential quality of care and depression outcomes...

..The authors used the experience sampling method to address this problem by collecting comparative data on moment-in-time work performance among service workers who were depressed and those who were not depressed...

..Bipolar disorder has been overlooked both because of the failure to distinguish between major depressive disorder and bipolar disorder and by the failure to evaluate the workplace costs of mania/hypomania...

..This report describes the development and evaluation of a brief measure for assessing patient perception of providers' support for self-management of bipolar disorder...

..The authors report results from a 7-year prospective study of depression and mortality in 2,558 Medicare recipients age 65 and older...

..Confirmation of these results is required, however, in new samples. Additional research is also needed on innovative and cost-effective strategies to improve HRA response rates...

..As limited data exist on the effects of self-weighing on body mass index (BMI) among overweight adults with or without depression, this study seeks to examine this issue using data from a population-based epidemiologic survey...

..85 (SD = 0.65) in the usual-care comparison group. Addition of a brief, structured CBT program can significantly improve clinical outcomes for the large number of patients beginning antidepressant treatment in primary care...

..The authors developed, implemented, and pilot-tested intervention programs to provide effective care for chronic or recurrent depression...

..Key elements of effective care improvement programs include specific, evidence-based treatment protocols, organized patient education and active follow-up care...

..Explore the business case for enhanced depression care and establish a return on investment rationale for increased organizational involvement by employer-purchasers...

..The present analysis assessed whether differential bias in self-reports of height and weight as a function of depression influences the apparent strength of the association...

..It is concluded that lifestyle-related modifiable health risk factors significantly impact employee work performance...

..weight loss, nutrient intake, physical activity, depressive symptoms, functional impairment and disability in the two groups of women with comorbid obesity and depression randomly assigned to the two different intervention programs ..

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..Study #2 will use marketing research methods to examine consumer demand for treatment and pilot-test marketing interventions to increase demand. ..

..The proposed research is one component of an ongoing comprehensive program to understand and increase consumer demand for effective depression treatment. ..

..e. 12-18 mos) Incremental cost and cost-effectiveness of each intervention program compared to care as usual. ..

..Each of the intervention groups will be compared to the usual care group in terms of quality of care, clinical outcomes, functional outcomes, and treatment costs. ..

..We propose a set of targeted methodologic studies to prepare for a multi-site research consortium focused on predicting response to specific depression treatments. ..