G E Simon

Summary

Affiliation: Group Health Cooperative
Country: USA

Publications

  1. pmc Is treatment adherence consistent across time, across different treatments and across diagnoses?
    Gregory E Simon
    Group Health Research Institute, Seattle, WA 98101, USA
    Gen Hosp Psychiatry 35:195-201. 2013
  2. pmc Response to past depression treatments is not accurately recalled: comparison of structured recall and patient health questionnaire scores in medical records
    Gregory E Simon
    Group Health Research Institute, Seattle, WA 98101, USA
    J Clin Psychiatry 73:1503-8. 2012
  3. pmc Early dropout from psychotherapy for depression with group- and network-model therapists
    Gregory E Simon
    Group Health Research Institute, 1730 Minor Ave 1600, Seattle, WA 98101, USA
    Adm Policy Ment Health 39:440-7. 2012
  4. pmc Is dropout after a first psychotherapy visit always a bad outcome?
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA
    Psychiatr Serv 63:705-7. 2012
  5. pmc Synchrony of change in depressive symptoms, health status, and quality of life in persons with clinical depression
    Paula H Diehr
    Department of Biostatistics F 670 HSB, Box 357232, University of Washington, Seattle, WA 98195 7232, USA
    Health Qual Life Outcomes 4:27. 2006
  6. ncbi request reprint Long-term effectiveness and cost of a systematic care program for bipolar disorder
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, and Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98101, USA
    Arch Gen Psychiatry 63:500-8. 2006
  7. pmc Association between obesity and psychiatric disorders in the US adult population
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Arch Gen Psychiatry 63:824-30. 2006
  8. pmc Outcome of new benzodiazepine prescriptions to older adults in primary care
    Gregory E Simon
    Group Health Cooperative, Center for Health Studies, Seattle, WA 98101, USA
    Gen Hosp Psychiatry 28:374-8. 2006
  9. ncbi request reprint Recovery from depression predicts lower health services costs
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101 1448, USA
    J Clin Psychiatry 67:1226-31. 2006
  10. ncbi request reprint Suicide risk during antidepressant treatment
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Am J Psychiatry 163:41-7. 2006

Detail Information

Publications88

  1. pmc Is treatment adherence consistent across time, across different treatments and across diagnoses?
    Gregory E Simon
    Group Health Research Institute, Seattle, WA 98101, USA
    Gen Hosp Psychiatry 35:195-201. 2013
    ..The objective was to examine consistency of adherence across depression treatments and consistency of adherence between depression treatments and treatments for chronic medical illness...
  2. pmc Response to past depression treatments is not accurately recalled: comparison of structured recall and patient health questionnaire scores in medical records
    Gregory E Simon
    Group Health Research Institute, Seattle, WA 98101, USA
    J Clin Psychiatry 73:1503-8. 2012
    ..Data from a population-based survey were linked to electronic medical records to examine agreement between patients' recalled treatment response and depression severity scores in the medical records...
  3. pmc Early dropout from psychotherapy for depression with group- and network-model therapists
    Gregory E Simon
    Group Health Research Institute, 1730 Minor Ave 1600, Seattle, WA 98101, USA
    Adm Policy Ment Health 39:440-7. 2012
    ..Efforts to increase the effectiveness of psychotherapy may required different strategies in group- and network-model practice...
  4. pmc Is dropout after a first psychotherapy visit always a bad outcome?
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA
    Psychiatr Serv 63:705-7. 2012
    ..The authors compared outcomes reported by patients who did or did not return for treatment after an initial psychotherapy visit...
  5. pmc Synchrony of change in depressive symptoms, health status, and quality of life in persons with clinical depression
    Paula H Diehr
    Department of Biostatistics F 670 HSB, Box 357232, University of Washington, Seattle, WA 98195 7232, USA
    Health Qual Life Outcomes 4:27. 2006
    ..We followed 982 clinically depressed persons to determine which measures changed and whether the change was synchronous with change in depressive symptoms...
  6. ncbi request reprint Long-term effectiveness and cost of a systematic care program for bipolar disorder
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, and Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98101, USA
    Arch Gen Psychiatry 63:500-8. 2006
    ..Despite the availability of efficacious treatments, the long-term course of bipolar disorder is often unfavorable...
  7. pmc Association between obesity and psychiatric disorders in the US adult population
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Arch Gen Psychiatry 63:824-30. 2006
    ..Epidemiologic data suggest an association between obesity and depression, but findings vary across studies and suggest a stronger relationship in women than men...
  8. pmc Outcome of new benzodiazepine prescriptions to older adults in primary care
    Gregory E Simon
    Group Health Cooperative, Center for Health Studies, Seattle, WA 98101, USA
    Gen Hosp Psychiatry 28:374-8. 2006
    ..The objective of this study was to examine the indications for benzodiazepine use, and the baseline characteristics, duration of use and clinical outcomes of older primary care patients prescribed benzodiazepines...
  9. ncbi request reprint Recovery from depression predicts lower health services costs
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101 1448, USA
    J Clin Psychiatry 67:1226-31. 2006
    ..To examine the association between outcome of acute-phase depression treatment and subsequent health services costs...
  10. ncbi request reprint Suicide risk during antidepressant treatment
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Am J Psychiatry 163:41-7. 2006
    ..The authors used population-based data to evaluate the risk of suicide death and serious suicide attempt in relation to initiation of antidepressant treatment...
  11. ncbi request reprint Medical co-morbidity and validity of DSM-IV depression criteria
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Psychol Med 36:27-36. 2006
    ..Clinicians have questioned the validity of depression criteria in patients with chronic medical illness, but few empirical data address this question...
  12. pmc Principles for evidence-based drug formulary policy
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    J Gen Intern Med 20:964-8. 2005
    ..We also discuss how economic incentives are likely to influence selection of research questions, especially research related to drug-gene interactions and to identifying new indications for existing drugs...
  13. ncbi request reprint Diabetes complications and depression as predictors of health service costs
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Gen Hosp Psychiatry 27:344-51. 2005
    ..The aim of this study was to assess the relative contributions of diabetes complications, depression and comorbid medical disorders to health service costs in adults with diabetes...
  14. ncbi request reprint Randomized trial of a population-based care program for people with bipolar disorder
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Psychol Med 35:13-24. 2005
    ..This trial evaluated the effectiveness of a multi-component care management program in a population-based sample of people with bipolar disorder...
  15. ncbi request reprint Clinical and functional outcomes of depression treatment in patients with and without chronic medical illness
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Psychol Med 35:271-9. 2005
    ..We examine how clinical and functional outcomes of depression treatment compare in primary-care patients with and without chronic medical illness...
  16. ncbi request reprint Prevalence and predictors of depression treatment in an international primary care study
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative of Puget Sound, 1730 Minor Ave, Number 1600, Seattle, WA 98101, USA
    Am J Psychiatry 161:1626-34. 2004
    ..The purpose of the study was to evaluate the prevalence and predictors of depression treatment in a diverse cross-national sample of primary care patients...
  17. ncbi request reprint Telephone psychotherapy and telephone care management for primary care patients starting antidepressant treatment: a randomized controlled trial
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, Wash 98101, USA
    JAMA 292:935-42. 2004
    ..Both antidepressant medication and structured psychotherapy have been proven efficacious, but less than one third of people with depressive disorders receive effective levels of either treatment...
  18. ncbi request reprint Randomized trial of a telephone care management program for outpatients starting antidepressant treatment
    Gregory E Simon
    Group Health Cooperative, Center for Health Studies, 1730 Minor Avenue, Suite 1600, Seattle, WA 98101 1448, USA
    Psychiatr Serv 57:1441-5. 2006
    ..This study evaluated the effectiveness of a structured telephone-based care management program for patients in a prepaid health plan receiving new antidepressant prescriptions from psychiatrists...
  19. ncbi request reprint Cost-effectiveness of systematic depression treatment among people with diabetes mellitus
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98101, USA
    Arch Gen Psychiatry 64:65-72. 2007
    ..Depression co-occurring with diabetes mellitus is associated with higher health services costs, suggesting that more effective depression treatment might reduce use of other medical services...
  20. ncbi request reprint Suicide attempts among patients starting depression treatment with medications or psychotherapy
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Am J Psychiatry 164:1029-34. 2007
    ..This study compared the time patterns of suicide attempts among outpatients starting depression treatment with medication or psychotherapy...
  21. pmc Obesity, depression, and health services costs among middle-aged women
    Gregory E Simon
    Group Health Research Institute, Seattle, WA, USA
    J Gen Intern Med 26:1284-90. 2011
    ..Both obesity and depression have been associated with significant increases in health care costs. Previous research has not examined whether cost increases associated with obesity could be explained by confounding effects of depression...
  22. doi request reprint An online recovery plan program: can peer coaching increase participation?
    Gregory E Simon
    Group Health Research Institute, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA
    Psychiatr Serv 62:666-9. 2011
    ..A pilot study evaluated whether the addition of online coaching from a peer specialist increased participation in an online program featuring educational and interactive modules to promote self-management of bipolar disorder...
  23. pmc Randomized trial of depression follow-up care by online messaging
    Gregory E Simon
    Group Health Research Institute, 1730 Minor Ave, 1600, Seattle, WA 98101, USA
    J Gen Intern Med 26:698-704. 2011
    ..Telephone care management programs can address these gaps, but reliance on live contact makes such programs less available, less timely, and more expensive...
  24. pmc Association between change in depression and change in weight among women enrolled in weight loss treatment
    Gregory E Simon
    Group Health Research Institute, Seattle, WA 98101, USA
    Gen Hosp Psychiatry 32:583-9. 2010
    ..To examine the association between improvement in depression and loss of weight among women with depressive symptoms entering a behavioral weight loss program...
  25. pmc Personalized medicine for depression: can we match patients with treatments?
    Gregory E Simon
    Group Health Research Institute, Seattle, WA 98101, USA
    Am J Psychiatry 167:1445-55. 2010
    ..Response to specific depression treatments varies widely among individuals. Understanding and predicting that variation could have great benefits for people living with depression...
  26. doi request reprint Predictors of early dropout from psychotherapy for depression in community practice
    Gregory E Simon
    Group Health Research Institute, 1730 Minor Ave, Seattle, WA 98101 1448, USA
    Psychiatr Serv 61:684-9. 2010
    ..Data from a managed care health system were used to examine demographic, clinical, and health system predictors of early dropout from psychotherapy for depression...
  27. doi request reprint Incremental benefit and cost of telephone care management and telephone psychotherapy for depression in primary care
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Ste 1600, Seattle, WA 98101 1448, USA
    Arch Gen Psychiatry 66:1081-9. 2009
    ..Effectiveness of organized depression care programs is well established, but dissemination will depend on the balance of benefits and costs...
  28. pmc Are comparisons of consumer satisfaction with providers biased by nonresponse or case-mix differences?
    Gregory Simon
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Suite 1600, Seattle, WA 98101 1448, USA
    Psychiatr Serv 60:67-73. 2009
    ..This study examined how consumer satisfaction ratings differ between mental health care providers to determine whether comparison of ratings is biased by differences in survey response rates or consumer characteristics...
  29. doi request reprint Severity of mood symptoms and work productivity in people treated for bipolar disorder
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Bipolar Disord 10:718-25. 2008
    ..To evaluate the relationship between mood symptoms and work productivity in people with bipolar disorder...
  30. pmc Association between obesity and depression in middle-aged women
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Gen Hosp Psychiatry 30:32-9. 2008
    ..Evaluate the association between obesity and depression among middle-aged women...
  31. pmc Accuracy of recall for mania symptoms using a three month timeline follow-back interview
    Gregory E Simon
    Group Health Cooperative Center for Health Studies, Seattle, WA 98101, United States
    J Affect Disord 107:271-4. 2008
    ..Little research has examined the accuracy of recall for mood symptoms using retrospective timelines or life charts. We examined accuracy of recall for mania symptoms over a period of 3 months...
  32. ncbi request reprint Mood symptoms, functional impairment, and disability in people with bipolar disorder: specific effects of mania and depression
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    J Clin Psychiatry 68:1237-45. 2007
    ..To examine the relationship between changes in mood symptoms and changes in functioning or disability in people treated for bipolar disorder...
  33. ncbi request reprint Risk of suicide attempt and suicide death in patients treated for bipolar disorder
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Bipolar Disord 9:526-30. 2007
    ..To evaluate demographic and clinical predictors of suicide attempt and suicide death in a population-based sample of people treated for bipolar disorder (BD)...
  34. ncbi request reprint Mental health visits to complementary and alternative medicine providers
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
    Gen Hosp Psychiatry 26:171-7. 2004
    ..Among those seeking CAM care for mental disorders, concomitant treatment by conventional medical providers is common, but communication or coordination of care is rare...
  35. ncbi request reprint Outcomes of prenatal antidepressant exposure
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, 1730 Minor Avenue 1600, Seattle, WA 98101, USA
    Am J Psychiatry 159:2055-61. 2002
    ..This study evaluated the effects of prenatal antidepressant exposure on perinatal outcomes, congenital malformations, and early growth and development...
  36. ncbi request reprint Design and implementation of a randomized trial evaluating systematic care for bipolar disorder
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Bipolar Disord 4:226-36. 2002
    ..This report describes the design and implementation of a randomized trial evaluating a systematic program to improve quality and continuity of care for bipolar disorder...
  37. ncbi request reprint Health care utilization and costs among patients treated for bipolar disorder in an insured population
    G E Simon
    Center for Health Studies of the Group Health Cooperative of Puget Sound, Seattle, Washington 98101, USA
    Psychiatr Serv 50:1303-8. 1999
    ..The study examined health care utilization and costs among patients treated for bipolar-spectrum disorders in an insured population...
  38. ncbi request reprint An international study of the relation between somatic symptoms and depression
    G E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101 1448, USA
    N Engl J Med 341:1329-35. 1999
    ..Of the patients in the original sample, 5447 underwent a structured assessment of depressive and somatoform disorders...
  39. ncbi request reprint Cost-effectiveness of a collaborative care program for primary care patients with persistent depression
    G E Simon
    Center for Health Sudies, Group Health Cooperative, Seattle, Washington 98101 1148, USA
    Am J Psychiatry 158:1638-44. 2001
    ..The authors evaluated the incremental cost-effectiveness of stepped collaborative care for patients with persistent depressive symptoms after usual primary care management...
  40. doi request reprint Collaborative care for mood disorders
    Gregory Simon
    Group Health Cooperative Center for Health Studies, Seattle, WA 98101, USA
    Curr Opin Psychiatry 22:37-41. 2009
    ..Psychiatric and health services research literature was reviewed to identify recent studies regarding effectiveness, cost-effectiveness, and generalizability of collaborative care programs to improve treatment of mood disorders...
  41. pmc Randomised trial of monitoring, feedback, and management of care by telephone to improve treatment of depression in primary care
    G E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    BMJ 320:550-4. 2000
    ..To test the effectiveness of two programmes to improve the treatment of acute depression in primary care...
  42. ncbi request reprint Treatment process and outcomes for managed care patients receiving new antidepressant prescriptions from psychiatrists and primary care physicians
    G E Simon
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Suite 1600, Seattle, WA 98101 1448, USA
    Arch Gen Psychiatry 58:395-401. 2001
    ..This study compares baseline characteristics, process of care, and outcomes for managed care patients who received new antidepressant prescriptions from psychiatrists and primary care physicians...
  43. ncbi request reprint Depression and work productivity: the comparative costs of treatment versus nontreatment
    G E Simon
    Center for Health Studies, Group Health Cooperative of Puget Sound, USA
    J Occup Environ Med 43:2-9. 2001
    ..Randomized effectiveness trials are needed before we can conclude definitively that depression treatment results in productivity improvements sufficient to offset direct treatment costs...
  44. ncbi request reprint Large medical databases, population-based research, and patient confidentiality
    G E Simon
    Center ofr Health Studies, Group Health Cooperative, Seattle, WA 98101 1448, USA
    Am J Psychiatry 157:1731-7. 2000
    ..This article is a discussion of the use of large clinical databases in population-based research on psychiatric disorders...
  45. ncbi request reprint Long-term outcomes of initial antidepressant drug choice in a "real world" randomized trial
    G E Simon
    Center for Health Studies, University of Washington, Seattle, USA
    Arch Fam Med 8:319-25. 1999
    ..To compare the long-term clinical, quality-of-life, and economic outcomes after an initial prescription for fluoxetine, imipramine hydrochloride, or desipramine hydrochloride...
  46. ncbi request reprint Cost-effectiveness of systematic depression treatment for high utilizers of general medical care
    G E Simon
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Suite 1600, Seattle, WA 98101 1448, USA
    Arch Gen Psychiatry 58:181-7. 2001
    ..We examine the incremental cost-effectiveness of an organized depression management program for high utilizers of medical care...
  47. ncbi request reprint Cost implications of initial antidepressant selection in primary care
    G E Simon
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Washington, USA
    Pharmacoeconomics 13:61-70. 1998
    ..These findings support earlier studies suggesting that the use of fluoxetine as a first-line antidepressant in primary care will increase antidepressant drug costs, but will not significantly increase total treatment costs...
  48. ncbi request reprint Course of hypochondriasis in an international primary care study
    G E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, Washington, USA
    Gen Hosp Psychiatry 23:51-5. 2001
    ..Hypochondriasis is moderately stable over time. The clear distinction between hypochondriasis and anxiety/depressive disorders suggested by ICD-10 and DSM-IV may be difficult to accomplish in practice...
  49. ncbi request reprint Prevalence, burden, and treatment of insomnia in primary care
    G E Simon
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA 98101 1448, USA
    Am J Psychiatry 154:1417-23. 1997
    ..The prevalence, burden, and management of insomnia among primary care patients were evaluated...
  50. ncbi request reprint Course of depression, health services costs, and work productivity in an international primary care study
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA, USA
    Gen Hosp Psychiatry 24:328-35. 2002
    ....
  51. ncbi request reprint Cost-effectiveness of a program to prevent depression relapse in primary care
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101, USA
    Med Care 40:941-50. 2002
    ..Evaluate the incremental cost-effectiveness of a depression relapse prevention program in primary care...
  52. ncbi request reprint Can depression treatment in primary care reduce disability? A stepped care approach
    E H Lin
    Center for Health Studies, Group Health Cooperative of Puget Sound, Center for Health Studies, Met Park II, 1730 Minor Ave, Suite 1600, Seattle, WA 98101 1448, USA
    Arch Fam Med 9:1052-8. 2000
    ..To assess effects of stepped collaborative care depression intervention on disability...
  53. ncbi request reprint Can enhanced acute-phase treatment of depression improve long-term outcomes? A report of randomized trials in primary care
    E H Lin
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA 98101 1448, USA
    Am J Psychiatry 156:643-5. 1999
    ..The authors' goal was to determine whether improved outcomes from enhanced acute-phase (3-month) treatment for depression in primary care persisted...
  54. ncbi request reprint Understanding cross-national differences in depression prevalence
    G E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101 1448, USA
    Psychol Med 32:585-94. 2002
    ..BACKGROUND. Previous epidemiological studies indicate large cross-national differences in prevalence of depression...
  55. ncbi request reprint Outcomes of "inadequate" antidepressant treatment
    G E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101-1448, USA
    J Gen Intern Med 10:663-70. 1995
    ..Efforts to increase the intensity of depression treatment in primary care should focus on the subgroup of patients who fail to respond to initial treatment...
  56. ncbi request reprint Psychiatric illness in patients with chronic fatigue and those with rheumatoid arthritis
    W J Katon
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195
    J Gen Intern Med 6:277-85. 1991
    ..Centers for Disease Control criteria for CFS did not select a subset of chronic fatigue patients who could be differentiated on disability or psychosocial parameters from patients with chronic fatigue who did not meet CDC criteria...
  57. pmc Does physician education on depression management improve treatment in primary care?
    E H Lin
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Wash 98101, USA
    J Gen Intern Med 16:614-9. 2001
    ..To assess the effect of physician training on management of depression...
  58. pmc Long-term prognosis of depression in primary care
    G E Simon
    Investigator, Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Bull World Health Organ 78:439-45. 2000
    ..This suggests that more systematic and effective depression treatment programmes might have an important effect on long-term course and reduce the overall burden of chronic and recurrent depression...
  59. ncbi request reprint Telephone counseling as an adjunct to antidepressant treatment in the primary care system. A pilot study
    S Tutty
    Group Health Cooperative Center for Health Studies, Seattle, Wash, USA
    Eff Clin Pract 3:170-8. 2000
    ..Many clinical and logistical barriers exist in the primary care model for treating adult depression...
  60. ncbi request reprint A randomized trial of relapse prevention of depression in primary care
    W Katon
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Box 35 6560, Seattle, WA 98195, USA
    Arch Gen Psychiatry 58:241-7. 2001
    ..We hypothesized that a relapse prevention intervention would improve adherence to antidepressant medication and improve depression outcomes in high-risk patients compared with usual primary care...
  61. pmc Predictors of outcome in a primary care depression trial
    E A Walker
    Department of Psychiatry and Behavioral Sciences, University of Washington Medical School, Seattle, Wash 98195, USA
    J Gen Intern Med 15:859-67. 2000
    ..We examined whether depression severity, comorbid psychiatric illness, and personality factors might play a role in this lack of response...
  62. ncbi request reprint Behavioural factors associated with symptom outcomes in a primary care-based depression prevention intervention trial
    E Ludman
    Center for Health Studies, Group Health Cooperative, Department of Psychiatry and Behavioral Sciences, University of Washington Medical School, Seattle, WA 98101, USA
    Psychol Med 33:1061-70. 2003
    ..We evaluated the effects of this intervention on behavioural processes and identified process predictors of improved depressive symptoms...
  63. ncbi request reprint Stepped collaborative care for primary care patients with persistent symptoms of depression: a randomized trial
    W Katon
    Department of Psychiatry and Behavioral Sciences, University of Washington Medical School, Seattle 98195, USA
    Arch Gen Psychiatry 56:1109-15. 1999
    ..Despite improvements in the accuracy of diagnosing depression and use of medications with fewer side effects, many patients treated with antidepressant medications by primary care physicians have persistent symptoms...
  64. ncbi request reprint Population-based care of depression: effective disease management strategies to decrease prevalence
    W Katon
    Department of Psychiatry and Behavioral Sciences, University of Washington Medical School, Seattle, USA
    Gen Hosp Psychiatry 19:169-78. 1997
    ..We apply these concepts to the organization of services for patients with major depression...
  65. ncbi request reprint A randomized controlled trial of CQI teams and academic detailing: can they alter compliance with guidelines?
    H I Goldberg
    University of Washington, Seattle, USA
    Jt Comm J Qual Improv 24:130-42. 1998
    ....
  66. ncbi request reprint Depressive symptoms and the cost of health services in HMO patients aged 65 years and older. A 4-year prospective study
    J Unutzer
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195, USA
    JAMA 277:1618-23. 1997
    ..To examine whether depressive symptoms in older adults contribute to increased cost of general medical services...
  67. ncbi request reprint Rethinking practitioner roles in chronic illness: the specialist, primary care physician, and the practice nurse
    W Katon
    Department of Psychiatry and Behavioral Sciences, Box 356560 University of Washington Medical School, Seattle, WA 98195, USA
    Gen Hosp Psychiatry 23:138-44. 2001
    ..These population-based methods to improve care of chronic illness require reorganizing the roles of specialists, primary care physicians, and nurses...
  68. ncbi request reprint A randomized trial of telephone psychotherapy and pharmacotherapy for depression: continuation and durability of effects
    Evette J Ludman
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101 1448, USA
    J Consult Clin Psychol 75:257-66. 2007
    ..85 (SD = 0.65) in the usual-care comparison group. Addition of a brief, structured CBT program can significantly improve clinical outcomes for the large number of patients beginning antidepressant treatment in primary care...
  69. ncbi request reprint A measure for assessing patient perception of provider support for self-management of bipolar disorder
    Evette J Ludman
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Bipolar Disord 4:249-53. 2002
    ..This report describes the development and evaluation of a brief measure for assessing patient perception of providers' support for self-management of bipolar disorder...
  70. ncbi request reprint Depressive symptoms and mortality in a prospective study of 2,558 older adults
    Jurgen Unutzer
    Center for Health Services Research, UCLA Neuropsychiatric Institute, 10920 Wilshire Boulevard, Suite 300, Los Angeles, CA 90024, USA
    Am J Geriatr Psychiatry 10:521-30. 2002
    ..The authors report results from a 7-year prospective study of depression and mortality in 2,558 Medicare recipients age 65 and older...
  71. ncbi request reprint Effects of major depression on moment-in-time work performance
    Philip S Wang
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Am J Psychiatry 161:1885-91. 2004
    ..The authors used the experience sampling method to address this problem by collecting comparative data on moment-in-time work performance among service workers who were depressed and those who were not depressed...
  72. pmc Prevalence and effects of mood disorders on work performance in a nationally representative sample of U.S. workers
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Am J Psychiatry 163:1561-8. 2006
    ..Bipolar disorder has been overlooked both because of the failure to distinguish between major depressive disorder and bipolar disorder and by the failure to evaluate the workplace costs of mania/hypomania...
  73. ncbi request reprint Effects of efforts to increase response rates on a workplace chronic condition screening survey
    Philip S Wang
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Med Care 40:752-60. 2002
    ..We evaluated these concerns by examining the prevalences and work impairments associated with chronic conditions across four HRA subsamples that differed in intensity of recruitment effort...
  74. ncbi request reprint Suicide risk in bipolar disorder during treatment with lithium and divalproex
    Frederick K Goodwin
    Department of Psychiatry, George Washington University Medical Center, Washington, DC 20037, USA
    JAMA 290:1467-73. 2003
    ....
  75. ncbi request reprint Enhancing adherence to prevent depression relapse in primary care
    Elizabeth H B Lin
    Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
    Gen Hosp Psychiatry 25:303-10. 2003
    ....
  76. ncbi request reprint 'Bipolarity' in bipolar disorder: distribution of manic and depressive symptoms in a treated population
    Mark S Bauer
    VAMC 116R, 830 Chalkstone Avenue, Providence, RI 02908 4799, USA
    Br J Psychiatry 187:87-8. 2005
    ..Depressive and manic symptoms were positively, not inversely, correlated, and their co-occurrence was associated with worse quality of life. Implications for the DSM and ICD nosological systems are discussed...
  77. ncbi request reprint Social and economic burden of mood disorders
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101, USA
    Biol Psychiatry 54:208-15. 2003
    ..We must recall, however, that economic benefits of treatment for mood disorders are secondary to the principal objective of relieving human suffering...
  78. ncbi request reprint Evidence review: efficacy and effectiveness of antidepressant treatment in primary care
    Gregory E Simon
    Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
    Gen Hosp Psychiatry 24:213-24. 2002
    ..Key elements of effective care improvement programs include specific, evidence-based treatment protocols, organized patient education and active follow-up care...
  79. pmc Relation of body mass index to depression and weighing frequency in overweight women
    Jennifer A Linde
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S 2nd Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Prev Med 45:75-9. 2007
    ..As limited data exist on the effects of self-weighing on body mass index (BMI) among overweight adults with or without depression, this study seeks to examine this issue using data from a population-based epidemiologic survey...
  80. ncbi request reprint Community-based treatment of late life depression an expert panel-informed literature review
    John T Frederick
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington 98104, USA
    Am J Prev Med 33:222-49. 2007
    ..To present findings from an expert panel-informed literature review on community-based treatment of late-life depression...
  81. ncbi request reprint The antidepressant quandary--considering suicide risk when treating adolescent depression
    Gregory E Simon
    Center for Health Studies at Group Health Cooperative, Seattle, USA
    N Engl J Med 355:2722-3. 2006
  82. ncbi request reprint How can we know whether antidepressants increase suicide risk?
    Gregory E Simon
    Am J Psychiatry 163:1861-3. 2006
  83. pmc Telephone screening, outreach, and care management for depressed workers and impact on clinical and work productivity outcomes: a randomized controlled trial
    Philip S Wang
    Division of Services and Intervention Research, National Institute of Mental Health, Rockville, Maryland, USA
    JAMA 298:1401-11. 2007
    ..Organized depression care programs significantly improve treatment quality, but employer purchasers have been slow to adopt these programs based on lack of evidence for cost-effectiveness from their perspective...
  84. ncbi request reprint The association of patient relationship style and outcomes in collaborative care treatment for depression in patients with diabetes
    Paul S Ciechanowski
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195 6560, USA
    Med Care 44:283-91. 2006
    ..We sought to determine whether relationship style in patients with diabetes receiving depression treatment is associated with differential quality of care and depression outcomes...
  85. ncbi request reprint A pilot study of telephone care management and structured disease self-management groups for chronic depression
    Evette J Ludman
    Group Health Center for Health Studies, 1730 Minor Avenue, Seattle, WA 98101, USA
    Psychiatr Serv 58:1065-72. 2007
    ..The authors developed, implemented, and pilot-tested intervention programs to provide effective care for chronic or recurrent depression...
  86. ncbi request reprint The association between work performance and physical activity, cardiorespiratory fitness, and obesity
    Nicolaas P Pronk
    Center for Health Promotion, HealthPartners, Minneapolis, Minnesota 55440 1309, USA
    J Occup Environ Med 46:19-25. 2004
    ..It is concluded that lifestyle-related modifiable health risk factors significantly impact employee work performance...
  87. pmc Does clinical depression affect the accuracy of self-reported height and weight in obese women?
    Robert W Jeffery
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Obesity (Silver Spring) 16:473-5. 2008
    ..The present analysis assessed whether differential bias in self-reports of height and weight as a function of depression influences the apparent strength of the association...
  88. doi request reprint Making the business case for enhanced depression care: the National Institute of Mental Health-harvard Work Outcomes Research and Cost-effectiveness Study
    Philip S Wang
    Division of Services and Intervention Research, National Institute of Mental Health, Rockville, MD 20892 9629, USA
    J Occup Environ Med 50:468-75. 2008
    ..Explore the business case for enhanced depression care and establish a return on investment rationale for increased organizational involvement by employer-purchasers...

Research Grants27

  1. Epidemiology and Care of Comorbid Obesity and Depression
    Gregory Simon; Fiscal Year: 2006
    ..weight loss, nutrient intake, physical activity, depressive symptoms, functional impairment and disability in the two groups of women with comorbid obesity and depression randomly assigned to the two different intervention programs ..
  2. Pilot Trial of Peer Support for Bipolar Disorder
    Gregory Simon; Fiscal Year: 2006
    ..abstract_text> ..
  3. Patient-Centered Interventions for Mood Disorders
    Gregory Simon; Fiscal Year: 2007
    ..Study #2 will use marketing research methods to examine consumer demand for treatment and pilot-test marketing interventions to increase demand. ..
  4. Modeling Adherence to Psychotherapy for Depression
    Gregory Simon; Fiscal Year: 2009
    ..The proposed research is one component of an ongoing comprehensive program to understand and increase consumer demand for effective depression treatment. ..
  5. POPULATION-BASED MANAGEMENT OF DEPRESSION
    Gregory Simon; Fiscal Year: 2003
    ..e. 12-18 mos) Incremental cost and cost-effectiveness of each intervention program compared to care as usual. ..
  6. POPULATION BASED MANAGEMENT OF DEPRESSION
    Gregory Simon; Fiscal Year: 1999
    ..Each of the intervention groups will be compared to the usual care group in terms of quality of care, clinical outcomes, functional outcomes, and treatment costs. ..
  7. Can Longitudinal Population-Based Data Help to Personalize Depression Treatment?
    Gregory E Simon; Fiscal Year: 2010
    ..We propose a set of targeted methodologic studies to prepare for a multi-site research consortium focused on predicting response to specific depression treatments. ..