Pearl Grimes

Summary

Country: USA

Publications

  1. doi request reprint Continuous therapy followed by a maintenance therapy regimen with a triple combination cream for melasma
    Pearl E Grimes
    Division of Dermatology, University of California, Los Angeles, California, USA
    J Am Acad Dermatol 62:962-7. 2010
  2. ncbi request reprint Tazarotene cream for postinflammatory hyperpigmentation and acne vulgaris in darker skin: a double-blind, randomized, vehicle-controlled study
    Pearl Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 77:45-50. 2006
  3. ncbi request reprint An efficacy study of 3 commercially available hydroquinone 4% treatments for melasma
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 80:497-502. 2007
  4. ncbi request reprint Light microscopic, immunohistochemical, and ultrastructural alterations in patients with melasma
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA 90004, USA
    Am J Dermatopathol 27:96-101. 2005
  5. ncbi request reprint New insights and new therapies in vitiligo
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    JAMA 293:730-5. 2005
  6. ncbi request reprint A microsponge formulation of hydroquinone 4% and retinol 0.15% in the treatment of melasma and postinflammatory hyperpigmentation
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 74:362-8. 2004
  7. ncbi request reprint Topical tacrolimus therapy for vitiligo: therapeutic responses and skin messenger RNA expression of proinflammatory cytokines
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, and the Division of Dermatology, David Geffen School of Medicine, University of California, Los Angeles, USA
    J Am Acad Dermatol 51:52-61. 2004
  8. doi request reprint A four-month randomized, double-blind evaluation of the efficacy of botulinum toxin type A for the treatment of glabellar lines in women with skin types V and VI
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, California, USA
    Dermatol Surg 35:429-35; discussion 435-6. 2009
  9. ncbi request reprint Evaluation of inherent differences between African American and white skin surface properties using subjective and objective measures
    Pearl Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 73:392-6. 2004
  10. doi request reprint Management of hyperpigmentation in darker racial ethnic groups
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA
    Semin Cutan Med Surg 28:77-85. 2009

Detail Information

Publications22

  1. doi request reprint Continuous therapy followed by a maintenance therapy regimen with a triple combination cream for melasma
    Pearl E Grimes
    Division of Dermatology, University of California, Los Angeles, California, USA
    J Am Acad Dermatol 62:962-7. 2010
    ..Melasma is often recalcitrant to treatment. Triple combination (TC) cream is an effective and approved treatment for melasma...
  2. ncbi request reprint Tazarotene cream for postinflammatory hyperpigmentation and acne vulgaris in darker skin: a double-blind, randomized, vehicle-controlled study
    Pearl Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 77:45-50. 2006
    ..In our study, tazarotene cream was effective and well tolerated in the treatment of PIH in patients with darker skin...
  3. ncbi request reprint An efficacy study of 3 commercially available hydroquinone 4% treatments for melasma
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 80:497-502. 2007
    ..15% with antioxidants is safe and effective for use in treating melasma, and the data show that this novel nonsteroidal product should be considered when weighing long-term treatment options...
  4. ncbi request reprint Light microscopic, immunohistochemical, and ultrastructural alterations in patients with melasma
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA 90004, USA
    Am J Dermatopathol 27:96-101. 2005
    ..The results of this study suggest that melasma is a consequence of specific hyperfunctional melanocytes that cause excessive melanin deposition in the epidermis and dermis...
  5. ncbi request reprint New insights and new therapies in vitiligo
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    JAMA 293:730-5. 2005
  6. ncbi request reprint A microsponge formulation of hydroquinone 4% and retinol 0.15% in the treatment of melasma and postinflammatory hyperpigmentation
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 74:362-8. 2004
    ..Microentrapped HQ 4% was well tolerated, with only one patient discontinuing because of an allergic reaction, which was not considered serious. In this open-label study, microentrapped HQ 4% with retinol 0.15% was safe and effective...
  7. ncbi request reprint Topical tacrolimus therapy for vitiligo: therapeutic responses and skin messenger RNA expression of proinflammatory cytokines
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, and the Division of Dermatology, David Geffen School of Medicine, University of California, Los Angeles, USA
    J Am Acad Dermatol 51:52-61. 2004
    ..Previous studies have documented humoral and cell-mediated immunologic defects in patients with vitiligo...
  8. doi request reprint A four-month randomized, double-blind evaluation of the efficacy of botulinum toxin type A for the treatment of glabellar lines in women with skin types V and VI
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, California, USA
    Dermatol Surg 35:429-35; discussion 435-6. 2009
    ..Histologic differences (e.g., dermal thickness, collagen fibers) between Caucasian and other racial and ethnic groups may affect wrinkle formation and influence responses to treatment with botulinum toxin type A (BoNT-A)...
  9. ncbi request reprint Evaluation of inherent differences between African American and white skin surface properties using subjective and objective measures
    Pearl Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 73:392-6. 2004
    ....
  10. doi request reprint Management of hyperpigmentation in darker racial ethnic groups
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA
    Semin Cutan Med Surg 28:77-85. 2009
    ..Maximal results are best achieved with repetitive, superficial, resurfacing modalities. In addition, ultraviolet protective measures such as broad-spectrum sunscreens are fundamental to the successful management of these conditions...
  11. ncbi request reprint Topical tacrolimus for repigmentation of vitiligo
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA, USA
    J Am Acad Dermatol 47:789-91. 2002
    ..Moderate to excellent repigmentation was achieved in 5 patients. Although the number of cases in this noncontrolled, nonblinded series is small, tacrolimus ointment may be an efficacious and safe treatment option for vitiligo...
  12. doi request reprint Safety and effectiveness of hyaluronic acid fillers in skin of color
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA, USA
    J Cosmet Dermatol 8:162-8. 2009
    ..To assess the safety and effectiveness of hyaluronic acid (HA) fillers in skin of color...
  13. ncbi request reprint Community-based trial of a triple-combination agent for the treatment of facial melasma
    Pearl Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 77:177-84. 2006
    ....
  14. ncbi request reprint Treating epidermal melasma with a 4% hydroquinone skin care system plus tretinoin cream 0.025%
    Pearl Grimes
    Vitiligo and Pigmentation Institute of Southern California, 5670 Wilshire Blvd, Ste 650, Los Angeles, CA 90036, USA
    Cutis 91:47-54. 2013
    ..The 4% hydroquinone skin care system plus tretinoin cream 0.025% is effective and well-tolerated in the treatment of melasma...
  15. ncbi request reprint Phase 4 study to assess tretinoin pump for the treatment of facial acne
    Lawrence F Eichenfield
    Rady Children s Hospital, San Diego, CA, USA
    J Drugs Dermatol 7:1129-36. 2008
    ..Most side effects were characteristic of topical retinoids. These results indicate TGM in a pump dispenser as an effective, well-tolerated acne treatment that is associated with a high rate of compliance...
  16. ncbi request reprint Microdermabrasion
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, David Geffen School of Medicine, University of California Los Angeles, CA, USA
    Dermatol Surg 31:1160-5; discussion 1165. 2005
    ..Microdermabrasion has become one of the most popular forms of superficial resurfacing. The benefits and efficacy of microdermabrasion remain an intensely debated topic among dermatologic surgeons...
  17. ncbi request reprint White patches and bruised souls: advances in the pathogenesis and treatment of vitiligo
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California and the Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90004, USA
    J Am Acad Dermatol 51:S5-7. 2004
  18. doi request reprint Surgical reconstruction of nasal sarcoidosis: a case report
    Malcolm A Lesavoy
    Department of Plastic and Reconstructive Surgery and Hand Surgery, UCLA School of Medicine Los Angeles, CA, USA
    Ann Plast Surg 64:800-2. 2010
    ..Although severe nasal deformities caused by sarcoidosis are very uncommon, this case demonstrates a simple and straight forward surgical approach to obtain an excellent nasal reconstruction...
  19. ncbi request reprint Increasing our understanding of pigmentary disorders
    Pearl Grimes
    Vitiligo and Pigmentation Institute of Southern California, Division of Dermatology, University of California, Los Angeles, CA, USA
    J Am Acad Dermatol 54:S255-61. 2006
    ..This article also reports on the new health-related quality-of-life instrument (MELASQOL) that has been developed for women with melasma...
  20. ncbi request reprint The use of polyhydroxy acids (PHAs) in photoaged skin
    Pearl E Grimes
    Vitiligo and Pigmentation Institute of Southern California, Los Angeles, USA
    Cutis 73:3-13. 2004
    ..Finally, PHA-containing products were shown to be compatible with African American, Caucasian, and Hispanic/Asian skin and provided significant improvements in photoaging in these populations...
  21. ncbi request reprint Skin barrier changes induced by aluminum oxide and sodium chloride microdermabrasion
    Poonam Rajan
    University of British Columbia, Vancouver, British Columbia, Canada
    Dermatol Surg 28:390-3. 2002
    ..Microdermabrasion has become an extremely popular method for superficial resurfacing. Despite the popularity of this technique, published studies of skin barrier function changes following microdermabrasion are lacking...
  22. ncbi request reprint Idiopathic CD4+T-cell lymphocytopenia associated with vitiligo
    Paul S Yamauchi
    Division of Dermatology, University of California Los Angeles School of Medicine, USA
    J Am Acad Dermatol 46:779-82. 2002
    ..He also had incidental psoriasis. The correlation between ICTL and autoimmune vitiligo suggests an aberration in the immune surveillance that leads to an abnormal response of CD4+ T lymphocytes in the host...