M J Lyons

Summary

Affiliation: Greenwood Genetic Center
Country: USA

Publications

  1. ncbi request reprint Specificity of familial vulnerability for alcoholism versus major depression in men
    Michael J Lyons
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    J Nerv Ment Dis 194:809-17. 2006
  2. doi request reprint Unbalanced translocation involving partial trisomy 9p and partial monosomy yq with neurodevelopmental delays
    Michael J Lyons
    Greenwood Genetic Center, Greenwood, Charleston, SC 29418, USA
    J Child Neurol 28:524-6. 2013
  3. doi request reprint Novel CLCN1 mutation in carbamazepine-responsive myotonia congenita
    Michael J Lyons
    Greenwood Genetic Center, Greenwood, South Carolina 29418, USA
    Pediatr Neurol 42:365-8. 2010
  4. doi request reprint Clinical experience in the evaluation of 30 patients with a prior diagnosis of FG syndrome
    M J Lyons
    Greenwood Genetic Center Charleston Office, 3520 W Montague Ave, Ste 104, North Charleston, SC 29418, USA
    J Med Genet 46:9-13. 2009
  5. ncbi request reprint Early onset alpha-mannosidosis with slow progression in three Hispanic males
    Michael J Lyons
    Greenwood Genetic Center, Greenwood, South Carolina, USA
    Dev Med Child Neurol 49:854-7. 2007
  6. pmc Clinical and molecular phenotype of Aicardi-Goutieres syndrome
    Gillian Rice
    Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, LS9 7TF, UK
    Am J Hum Genet 81:713-25. 2007
  7. pmc Common genetic liability to major depression and posttraumatic stress disorder in men
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, United States
    J Affect Disord 105:109-15. 2008
  8. ncbi request reprint Is the Wisconsin Card Sorting Test a useful neurocognitive endophenotype?
    William S Kremen
    Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego, La Jolla, California 92093 0738, USA
    Am J Med Genet B Neuropsychiatr Genet 144:403-6. 2007
  9. ncbi request reprint Pretrauma cognitive ability and risk for posttraumatic stress disorder: a twin study
    William S Kremen
    Department of Psychiatry and Center for Behavioral Genomics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Arch Gen Psychiatry 64:361-8. 2007
  10. ncbi request reprint Is there heterogeneity among syndromes of substance use disorder for illicit drugs?
    Cheryl Beseler
    Center for Behavioral Genomics, Department of Psychiatry, University of California, 9500 Gilman Drive, Mail Code 0603, La Jolla, San Diego, CA 92093, and Veterans Medical Research Foundation, La Jolla 92161, USA
    Addict Behav 31:929-47. 2006

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Specificity of familial vulnerability for alcoholism versus major depression in men
    Michael J Lyons
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    J Nerv Ment Dis 194:809-17. 2006
    ..Our data are most consistent with a mechanism of reciprocal causation, whereby MD increases risk for AD and AD increases risk of MD...
  2. doi request reprint Unbalanced translocation involving partial trisomy 9p and partial monosomy yq with neurodevelopmental delays
    Michael J Lyons
    Greenwood Genetic Center, Greenwood, Charleston, SC 29418, USA
    J Child Neurol 28:524-6. 2013
    ..Additional evaluations of this child and his parents allowed an accurate assessment of his diagnosis, long-term prognosis, and chance of recurrence...
  3. doi request reprint Novel CLCN1 mutation in carbamazepine-responsive myotonia congenita
    Michael J Lyons
    Greenwood Genetic Center, Greenwood, South Carolina 29418, USA
    Pediatr Neurol 42:365-8. 2010
    ..The patient received carbamazepine treatment for 1 year, resulting in decreased muscle stiffness, increased strength, and improved quality of life in school and with peers...
  4. doi request reprint Clinical experience in the evaluation of 30 patients with a prior diagnosis of FG syndrome
    M J Lyons
    Greenwood Genetic Center Charleston Office, 3520 W Montague Ave, Ste 104, North Charleston, SC 29418, USA
    J Med Genet 46:9-13. 2009
    ..In 2007, a recurrent R961W mutation in the MED12 gene at Xq13 was found to cause FGS in six families, including the original family described by Opitz and Kaveggia. The phenotype was highly consistent in all the R961W positive patients...
  5. ncbi request reprint Early onset alpha-mannosidosis with slow progression in three Hispanic males
    Michael J Lyons
    Greenwood Genetic Center, Greenwood, South Carolina, USA
    Dev Med Child Neurol 49:854-7. 2007
    ..This report illustrates the difficulty in determining a strict genotype-phenotype correlation in AMS, and supports screening for oligosaccharides in children with neurodevelopmental delay with mild phenotypic signs and symptoms...
  6. pmc Clinical and molecular phenotype of Aicardi-Goutieres syndrome
    Gillian Rice
    Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, LS9 7TF, UK
    Am J Hum Genet 81:713-25. 2007
    ..Our analysis defines the phenotypic spectrum of AGS and suggests a coherent mutation-screening strategy in this heterogeneous disorder. Additionally, our data indicate that at least one further AGS-causing gene remains to be identified...
  7. pmc Common genetic liability to major depression and posttraumatic stress disorder in men
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, United States
    J Affect Disord 105:109-15. 2008
    ..The degree to which a common genetic liability explains the etiology of the MD-PTSD association has not been quantified and has important implications for research and prevention...
  8. ncbi request reprint Is the Wisconsin Card Sorting Test a useful neurocognitive endophenotype?
    William S Kremen
    Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego, La Jolla, California 92093 0738, USA
    Am J Med Genet B Neuropsychiatr Genet 144:403-6. 2007
    ..Rather, we believe that our results suggest that some properties of this particular test make it undesirable for use as an endophenotype...
  9. ncbi request reprint Pretrauma cognitive ability and risk for posttraumatic stress disorder: a twin study
    William S Kremen
    Department of Psychiatry and Center for Behavioral Genomics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Arch Gen Psychiatry 64:361-8. 2007
    ..Cognitive deficits are associated with posttraumatic stress disorder (PTSD), but whether such deficits reflect sequelae or risk factors is not fully resolved...
  10. ncbi request reprint Is there heterogeneity among syndromes of substance use disorder for illicit drugs?
    Cheryl Beseler
    Center for Behavioral Genomics, Department of Psychiatry, University of California, 9500 Gilman Drive, Mail Code 0603, La Jolla, San Diego, CA 92093, and Veterans Medical Research Foundation, La Jolla 92161, USA
    Addict Behav 31:929-47. 2006
    ....
  11. ncbi request reprint Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design
    Julia D Grant
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychol Med 36:109-18. 2006
    ..Early alcohol use is associated with abuse and dependence of licit and illicit substances later in life. The role of genetic and environmental factors in this association is not conclusive...
  12. ncbi request reprint Genetic and environmental contributions to the development of alcohol dependence in male twins
    I Chao Liu
    Department of Psychiatry, Cardinal Tien Hospital, Taipei, Taiwan
    Arch Gen Psychiatry 61:897-903. 2004
    ..Information on the heritability of the development of alcohol dependence could provide a better understanding of the importance of genetic components in disease transition...
  13. ncbi request reprint Stability, consistency, and heritability of electrodermal response lability in middle-aged male twins
    Andrew Crider
    Department of Psychology, Williams College, Williamstown, Massachusetts, USA
    Psychophysiology 41:501-9. 2004
    ..We discuss these findings in terms of an information processing account of individual differences in phasic EDR activation...
  14. ncbi request reprint A twin study of sexual behavior in men
    Michael J Lyons
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    Arch Sex Behav 33:129-36. 2004
    ..The data suggest that the observed association between age of initiation of sexual relations and having multiple partners is due to genetic influences common to both behaviors...