Research TopicsSpecies | M J LyonsSummaryAffiliation: Greenwood Genetic Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Specificity of familial vulnerability for alcoholism versus major depression in menMichael J Lyons
Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
J Nerv Ment Dis 194:809-17. 2006..Our data are most consistent with a mechanism of reciprocal causation, whereby MD increases risk for AD and AD increases risk of MD...
Unbalanced translocation involving partial trisomy 9p and partial monosomy yq with neurodevelopmental delaysMichael J Lyons
Greenwood Genetic Center, Greenwood, Charleston, SC 29418, USA
J Child Neurol 28:524-6. 2013..Additional evaluations of this child and his parents allowed an accurate assessment of his diagnosis, long-term prognosis, and chance of recurrence...- Novel CLCN1 mutation in carbamazepine-responsive myotonia congenitaMichael J Lyons
Greenwood Genetic Center, Greenwood, South Carolina 29418, USA
Pediatr Neurol 42:365-8. 2010..The patient received carbamazepine treatment for 1 year, resulting in decreased muscle stiffness, increased strength, and improved quality of life in school and with peers... - Clinical experience in the evaluation of 30 patients with a prior diagnosis of FG syndromeM J Lyons
Greenwood Genetic Center Charleston Office, 3520 W Montague Ave, Ste 104, North Charleston, SC 29418, USA
J Med Genet 46:9-13. 2009..In 2007, a recurrent R961W mutation in the MED12 gene at Xq13 was found to cause FGS in six families, including the original family described by Opitz and Kaveggia. The phenotype was highly consistent in all the R961W positive patients... - Early onset alpha-mannosidosis with slow progression in three Hispanic malesMichael J Lyons
Greenwood Genetic Center, Greenwood, South Carolina, USA
Dev Med Child Neurol 49:854-7. 2007..This report illustrates the difficulty in determining a strict genotype-phenotype correlation in AMS, and supports screening for oligosaccharides in children with neurodevelopmental delay with mild phenotypic signs and symptoms... 
Clinical and molecular phenotype of Aicardi-Goutieres syndromeGillian Rice
Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, LS9 7TF, UK
Am J Hum Genet 81:713-25. 2007..Our analysis defines the phenotypic spectrum of AGS and suggests a coherent mutation-screening strategy in this heterogeneous disorder. Additionally, our data indicate that at least one further AGS-causing gene remains to be identified...- Common genetic liability to major depression and posttraumatic stress disorder in menKarestan C Koenen
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, United States
J Affect Disord 105:109-15. 2008..The degree to which a common genetic liability explains the etiology of the MD-PTSD association has not been quantified and has important implications for research and prevention... - Is the Wisconsin Card Sorting Test a useful neurocognitive endophenotype?William S Kremen
Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego, La Jolla, California 92093 0738, USA
Am J Med Genet B Neuropsychiatr Genet 144:403-6. 2007..Rather, we believe that our results suggest that some properties of this particular test make it undesirable for use as an endophenotype... - Pretrauma cognitive ability and risk for posttraumatic stress disorder: a twin studyWilliam S Kremen
Department of Psychiatry and Center for Behavioral Genomics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Arch Gen Psychiatry 64:361-8. 2007..Cognitive deficits are associated with posttraumatic stress disorder (PTSD), but whether such deficits reflect sequelae or risk factors is not fully resolved... - Is there heterogeneity among syndromes of substance use disorder for illicit drugs?Cheryl Beseler
Center for Behavioral Genomics, Department of Psychiatry, University of California, 9500 Gilman Drive, Mail Code 0603, La Jolla, San Diego, CA 92093, and Veterans Medical Research Foundation, La Jolla 92161, USA
Addict Behav 31:929-47. 2006.... - Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin designJulia D Grant
Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
Psychol Med 36:109-18. 2006..Early alcohol use is associated with abuse and dependence of licit and illicit substances later in life. The role of genetic and environmental factors in this association is not conclusive... - Genetic and environmental contributions to the development of alcohol dependence in male twinsI Chao Liu
Department of Psychiatry, Cardinal Tien Hospital, Taipei, Taiwan
Arch Gen Psychiatry 61:897-903. 2004..Information on the heritability of the development of alcohol dependence could provide a better understanding of the importance of genetic components in disease transition... - Stability, consistency, and heritability of electrodermal response lability in middle-aged male twinsAndrew Crider
Department of Psychology, Williams College, Williamstown, Massachusetts, USA
Psychophysiology 41:501-9. 2004..We discuss these findings in terms of an information processing account of individual differences in phasic EDR activation... - A twin study of sexual behavior in menMichael J Lyons
Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
Arch Sex Behav 33:129-36. 2004..The data suggest that the observed association between age of initiation of sexual relations and having multiple partners is due to genetic influences common to both behaviors...