Irwin Goldstein

Summary

Country: USA

Publications

  1. ncbi Prevention and treatment of erectile dysfunction using lifestyle changes and dietary supplements: what works and what is worthless, part I
    Mark A Moyad
    Department of Urology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0330, USA
    Urol Clin North Am 31:249-57. 2004
  2. ncbi Sexual medicine treatment: lifestyle or life quality? The import of language
    Irwin Goldstein
    J Sex Med 3:191-3. 2006
  3. ncbi Efficacy and safety of tadalafil in men with erectile dysfunction with a high prevalence of comorbid conditions: results from MOMENTUS: multiple observations in men with erectile dysfunction in National Tadalafil Study in the US
    Irwin Goldstein
    Milton, MA 02186, USA
    J Sex Med 4:166-75. 2007
  4. ncbi Erectile dysfunction: monitoring response to treatment in clinical practice--recommendations of an international study panel
    John Mulhall
    Department of Urology, Weill Medical College of Cornell University, Department of Urology, Memorial Sloan Kettering Cancer Center New York, NY, USA
    J Sex Med 4:448-64. 2007
  5. ncbi A clinical paradigm for the combined management of androgen insufficiency and erectile dysfunction
    Irwin Goldstein
    Sexual Medicine, Alvarado Hospital, 5555 Reservoir Drive, Suite 203, San Diego, CA 92120, USA
    Endocrinol Metab Clin North Am 36:435-52. 2007
  6. ncbi Streptozotocin-induced diabetes in the rat is associated with changes in vaginal hemodynamics, morphology and biochemical markers
    Noel N Kim
    Institute for Sexual Medicine, Department of Urology, Boston University School of Medicine, Boston, USA
    BMC Physiol 6:4. 2006
  7. ncbi Commentary - will medical solutions to sexual problems make sexological care and science obsolete?
    Irwin Goldstein
    University of California, San Diego, California, USA
    J Sex Marital Ther 33:439-41. 2007
  8. ncbi Current management strategies of the postmenopausal patient with sexual health problems
    Irwin Goldstein
    The Journal of Sexual Medicine, Milton, MA, USA
    J Sex Med 4:235-53. 2007
  9. ncbi Practical aspects in the management of vaginal atrophy and sexual dysfunction in perimenopausal and postmenopausal women
    Irwin Goldstein
    J Sex Med 2:154-65. 2005
  10. ncbi Women's sexual function improves when partners are administered vardenafil for erectile dysfunction: a prospective, randomized, double-blind, placebo-controlled trial
    Irwin Goldstein
    J Sex Med 2:819-32. 2005

Detail Information

Publications73

  1. ncbi Prevention and treatment of erectile dysfunction using lifestyle changes and dietary supplements: what works and what is worthless, part I
    Mark A Moyad
    Department of Urology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0330, USA
    Urol Clin North Am 31:249-57. 2004
    ..The time is more than ripe for patients to understand that heart health is tantamount to erectile health...
  2. ncbi Sexual medicine treatment: lifestyle or life quality? The import of language
    Irwin Goldstein
    J Sex Med 3:191-3. 2006
  3. ncbi Efficacy and safety of tadalafil in men with erectile dysfunction with a high prevalence of comorbid conditions: results from MOMENTUS: multiple observations in men with erectile dysfunction in National Tadalafil Study in the US
    Irwin Goldstein
    Milton, MA 02186, USA
    J Sex Med 4:166-75. 2007
    ..Limited efficacy and safety data exist from open-label clinical trials of phosphodiesterase 5 inhibitors in men with erectile dysfunction (ED) and multiple comorbid (MCM) conditions, historically a difficult group to treat...
  4. ncbi Erectile dysfunction: monitoring response to treatment in clinical practice--recommendations of an international study panel
    John Mulhall
    Department of Urology, Weill Medical College of Cornell University, Department of Urology, Memorial Sloan Kettering Cancer Center New York, NY, USA
    J Sex Med 4:448-64. 2007
    ..Clinical practice guidelines for management of erectile dysfunction (ED) provide limited direction in defining appropriate treatment goals with phosphodiesterase type 5 (PDE5) inhibitor therapy...
  5. ncbi A clinical paradigm for the combined management of androgen insufficiency and erectile dysfunction
    Irwin Goldstein
    Sexual Medicine, Alvarado Hospital, 5555 Reservoir Drive, Suite 203, San Diego, CA 92120, USA
    Endocrinol Metab Clin North Am 36:435-52. 2007
    ..This article focuses on a rational, evidence based clinical management paradigm that combines diagnosis and treatment of men who have androgen insufficiency and erectile dysfunction...
  6. ncbi Streptozotocin-induced diabetes in the rat is associated with changes in vaginal hemodynamics, morphology and biochemical markers
    Noel N Kim
    Institute for Sexual Medicine, Department of Urology, Boston University School of Medicine, Boston, USA
    BMC Physiol 6:4. 2006
    ..We further related these changes with estrogen receptor alpha (ERalpha) and androgen receptor (AR) expression...
  7. ncbi Commentary - will medical solutions to sexual problems make sexological care and science obsolete?
    Irwin Goldstein
    University of California, San Diego, California, USA
    J Sex Marital Ther 33:439-41. 2007
  8. ncbi Current management strategies of the postmenopausal patient with sexual health problems
    Irwin Goldstein
    The Journal of Sexual Medicine, Milton, MA, USA
    J Sex Med 4:235-53. 2007
    ..Sexual health concerns of menopausal women include decreases in sexual interest, arousal, lubrication, and orgasm, and increases in sexual pain, all of which may be associated with distress...
  9. ncbi Practical aspects in the management of vaginal atrophy and sexual dysfunction in perimenopausal and postmenopausal women
    Irwin Goldstein
    J Sex Med 2:154-65. 2005
    ..Vaginal atrophy is an important contributor to postmenopausal sexual dysfunction...
  10. ncbi Women's sexual function improves when partners are administered vardenafil for erectile dysfunction: a prospective, randomized, double-blind, placebo-controlled trial
    Irwin Goldstein
    J Sex Med 2:819-32. 2005
    ..There are limited data concerning the sexual function of women whose male partners receive pharmacological treatment for erectile dysfunction (ED)...
  11. ncbi The erection hardness score and its relationship to successful sexual intercourse
    Irwin Goldstein
    Sexual Medicine, Alvarado Hospital, University of California, San Diego, CA 92120, USA
    J Sex Med 5:2374-80. 2008
    ..Although it is intuitive that erection hardness and successful sexual intercourse (SSI) are related, the link has not been directly established...
  12. ncbi Avanafil for the treatment of erectile dysfunction: a multicenter, randomized, double-blind study in men with diabetes mellitus
    Irwin Goldstein
    San Diego Sexual Medicine, Alvarado Hospital, CA 92120, USA
    Mayo Clin Proc 87:843-52. 2012
    ..To prospectively assess the safety and effectiveness of the investigational phosphodiesterase 5 inhibitor avanafil to treat erectile dysfunction in men with diabetes mellitus...
  13. ncbi Recognizing and treating urogenital atrophy in postmenopausal women
    Irwin Goldstein
    San Diego Sexual Medicine Alvarado Hospital and Department of Surgery, University of California at San Diego, California, USA
    J Womens Health (Larchmt) 19:425-32. 2010
    ..All forms of vaginal estrogen therapy are effective and well tolerated, although vaginal tablets and rings may have fewer adverse effects and have higher rates of adherence than creams...
  14. ncbi A randomized, double-blind, placebo-controlled evaluation of the safety and efficacy of avanafil in subjects with erectile dysfunction
    Irwin Goldstein
    Sexual Medicine, Alvarado Hospital, San Diego, CA 92120, USA
    J Sex Med 9:1122-33. 2012
    ..Phosphodiesterase type 5 (PDE5) inhibitors have become standard treatment for erectile dysfunction (ED)...
  15. ncbi Persistent genital arousal disorder (PGAD): case report of long-term symptomatic management with electroconvulsive therapy
    Joanna B Korda
    San Diego State University, San Diego, CA, USA
    J Sex Med 6:2901-9. 2009
    ..With the worsening of PGAD symptoms, she developed severe depression and suicidal thoughts, resulting in her undergoing electroconvulsive therapy (ECT) as management...
  16. ncbi Characterization of hypoactive sexual desire disorder (HSDD) in men
    Leonard Derogatis
    Center for Sexual Medicine at Sheppard Pratt, Johns Hopkins Department of Psychiatry and Behavioural Sciences, Baltimore, MD 21285 6815, USA
    J Sex Med 9:812-20. 2012
    ..Little is known about Hypoactive Sexual Desire Disorder (HSDD) in men...
  17. ncbi Zotarolimus-eluting peripheral stents for the treatment of erectile dysfunction in subjects with suboptimal response to phosphodiesterase-5 inhibitors
    Jason H Rogers
    Division of Cardiovascular Medicine, University of California, Davis Medical Center, Sacramento, California, USA
    J Am Coll Cardiol 60:2618-27. 2012
    ....
  18. ncbi Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: a retrospective study in women with sexual dysfunction
    Claudia Panzer
    Department of Endocrinology, Boston University Medical Center, Boston, MA, USA
    J Sex Med 3:104-13. 2006
    ..OC use is associated with a decrease of androgen ovarian synthesis and an increase in the production of sex hormone-binding globulin (SHBG). There have been limited studies assessing SHBG values after discontinuation of OC use...
  19. ncbi Testosterone increases blood flow and expression of androgen and estrogen receptors in the rat vagina
    Abdulmaged M Traish
    Departments of Biochemistry, and Urology, Boston University School of Medicine, Boston, MA, USA
    J Sex Med 4:609-19. 2007
    ..The mechanisms by which testosterone modulates female genital sexual arousal responses are poorly understood...
  20. ncbi A three-dimensional theoretical model of the relationship between cavernosal expandability and percent cavernosal smooth muscle
    Haibiao Luo
    Department of Aerospace and Mechanical Engineering, College of Engineering, Boston University, Boston, MA, USA
    J Sex Med 4:644-5; discussion 651-55. 2007
    ....
  21. ncbi National differences in patient-clinician communication regarding hypoactive sexual desire disorder
    Irwin Goldstein
    Sexual Medicine, Alvarado Hospital, 6719 Alvarado Rd, Suite108, San Diego, CA 92120, USA
    J Sex Med 6:1349-57. 2009
    ..Despite greater awareness and openness about sexual problems among women, many patients remain reserved about discussing such problems with their doctor. Clinicians are often reluctant to ask about sexual dysfunction...
  22. ncbi Persistent genital arousal disorder: a case report in a woman with lifelong PGAD where serendipitous administration of varenicline tartrate resulted in symptomatic improvement
    Joanna B Korda
    Department of Psychology, San Diego State University, San Diego, CA, USA
    J Sex Med 6:1479-86. 2009
    ..Persistent genital arousal disorder (PGAD) in women is associated with feelings of persistent, spontaneous, intrusive, unrelenting, and unwanted physical arousal in the absence of conscious thoughts of sexual desire or sexual interest...
  23. ncbi Sexual experience of female partners of men with erectile dysfunction: the female experience of men's attitudes to life events and sexuality (FEMALES) study
    William A Fisher
    Department of Psychology, Social Science Centre 6430, University of Western Ontario, London, Ontario, Canada N6A 5C2
    J Sex Med 2:675-84. 2005
    ..Much research has explored the experience of erectile dysfunction (ED) among men with ED, but far less attention has been paid to the perceptions and sexual experiences of the female partners of men with ED...
  24. ncbi Improving the sexual quality of life of couples affected by erectile dysfunction: a double-blind, randomized, placebo-controlled trial of vardenafil
    William A Fisher
    Department of Psychology, Social Science Centre 6430, University of Western Ontario, London, Ontario, Canada N6A 5C2
    J Sex Med 2:699-708. 2005
    ....
  25. ncbi Summary of the recommendations on sexual dysfunctions in women
    Rosemary Basson
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    J Sex Med 1:24-34. 2004
    ..There are limited recommendation/guideline documents pertaining to the diagnosis and treatment of women's sexual dysfunctions...
  26. ncbi Growing up and seeking guidance
    Irwin Goldstein
    J Sex Med 5:1515-7. 2008
  27. ncbi Comparing vardenafil and sildenafil in the treatment of men with erectile dysfunction and risk factors for cardiovascular disease: a randomized, double-blind, pooled crossover study
    Eusebio Rubio-Aurioles
    Asociacion Mexicana para la Salud Sexual AC, Tlalpan, Mexico
    J Sex Med 3:1037-49. 2006
    ....
  28. ncbi Effects of ovariectomy and estrogen replacement on basal and pelvic nerve stimulated vaginal lubrication in an animal model
    Kweonsik Min
    Department of Urology, Inje University School of Medicine, Pusan, South Korea
    J Sex Marital Ther 29:77-84. 2003
    ..Estrogen replacement normalized lubrication values and tissue wet weight to control levels. In conclusion, vaginal tissue integrity and lubrication are diminished by ovariectomy and are normalized by estrogen replacement...
  29. ncbi Testosterone and erectile function: from basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction
    Abdulmaged M Traish
    Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA
    Eur Urol 52:54-70. 2007
    ....
  30. ncbi The journal of sexual medicine supports research and choice in women's sexual health management
    Sheryl Kingsberg
    J Sex Med 4:209-10. 2007
  31. ncbi Validation of the erection hardness score
    John P Mulhall
    Weill Medical College of Cornell University and Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Sex Med 4:1626-34. 2007
    ..Erection hardness is a fundamental component of erectile function, and is a very specific and easily monitored outcome. The Erection Hardness Score (EHS) is a single-item, patient-reported outcome (PRO) for scoring erection hardness...
  32. ncbi In the end, "sex is complicated"
    Irwin Goldstein
    J Sex Med 4:523-5. 2007
  33. ncbi The Treatment Satisfaction Scale (TSS) is a sensitive measure of treatment effectiveness for both patients and partners: results of a randomized controlled trial with vardenafil
    Raymond Rosen
    New England Research Institutes, 9 Galen Street, Watertown, MA 02472, USA
    J Sex Med 4:1009-21. 2007
    ..The ED Treatment Satisfaction Scale (TSS) is a brief, comprehensive self-report measure of patient and partner satisfaction...
  34. ncbi Patient education series. Erectile dysfunction
    Jean H Lewis
    Erectile Dysfunction Clinic, Veterans Affairs Medical Center, Minneapolis, MN, USA
    Nursing 35:64. 2005
  35. ncbi Pilot study of the endothelin-A receptor selective antagonist BMS-193884 for the treatment of erectile dysfunction
    Noel N Kim
    Department of Urology, Boston University School of Medicine, Massachusetts 02118, USA
    J Androl 23:76-83. 2002
    ..The disparity between the laboratory and clinical studies suggests that there may be differences between species with regard to the role of endothelin in erectile function...
  36. ncbi Biochemical and physiological mechanisms of female genital sexual arousal
    Abdulmaged M Traish
    Arch Sex Behav 31:393-400. 2002
    ..A comprehensive and integral understanding of female sexual function requires detailed investigation of the vascular, neurological (central and peripheral), and structural components of this complex physiological process...
  37. ncbi Efficacy of vardenafil and sildenafil in facilitating penile erection in an animal model
    Seong Choi
    Department of Urology, Boston University School of Medicine, Massachusetts 02118, USA
    J Androl 23:332-7. 2002
    ..On the basis of the biochemical data and physiological responses from this study, further clinical evaluation of vardenafil as treatment for erectile dysfunction is warranted...
  38. ncbi Erectile dysfunction
    Jean H Lewis
    ED Clinic, Veterans' Affairs Medical Center, Minneapolis, MN, USA
    Am J Nurs 103:48-57; quiz 57-8. 2003
  39. ncbi A review of the physiology and pharmacology of peripheral (vaginal and clitoral) female genital arousal in the animal model
    Ricardo Munarriz
    Institute for Sexual Medicine, Department of Urology, Boston University School of Medicine, 720 Harrison Ave, Suite 600, Boston, Massachusetts 02118, USA
    J Urol 170:S40-4; discussion S44-5. 2003
    ..CONCLUSIONS: To achieve improved understanding of the biological aspects of female sexual function, further research is needed in the physiology and pharmacology of peripheral (clitoral and vaginal) genital arousal in the animal model...
  40. ncbi Effects of medical or surgical castration on erectile function in an animal model
    Abdulmaged M Traish
    Department of Urology, Boston University School of Medicine, Massachusetts 02118, USA
    J Androl 24:381-7. 2003
    ..We conclude that androgen deprivation produces structural alterations in the corpus cavernosum leading to corporal veno-occlusive dysfunction...
  41. ncbi Erectile dysfunction in primary care
    Jean H Lewis
    Erectile Dysfunction Clinic, Veterans Affairs Medical Center Minneapolis, MN, USA
    Nurse Pract 29:42-6, 48-50, 55; quiz 55-7. 2004
  42. ncbi Oral sildenafil in the treatment of erectile dysfunction. 1998
    Irwin Goldstein
    J Urol 167:1197-203; discussion 1204. 2002
  43. ncbi Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference)
    John B Kostis
    University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Am J Cardiol 96:313-21. 2005
    ..Finally, further research on the role of PDE-5 inhibition in treating patients with other medical or cardiovascular disorders is recommended...
  44. ncbi Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind placebo-controlled fixed-dose study
    Irwin Goldstein
    Boston University Medical Center, Boston, Massachusetts 02118, USA
    Diabetes Care 26:777-83. 2003
    ..This study evaluated the efficacy and safety of vardenafil treatment for erectile dysfunction (ED) in men with diabetes...
  45. ncbi Androgen replacement therapy with dehydroepiandrosterone for androgen insufficiency and female sexual dysfunction: androgen and questionnaire results
    Ricardo Munarriz
    Boston University School of Medicine, Boston, Massachusetts, USA
    J Sex Marital Ther 28:165-73. 2002
    ..However, further research is needed, including prospective, multi-institution, placebo-controlled double-blind studies...
  46. ncbi Health care clinicians in sexual health medicine: focus on erectile dysfunction
    Jeffrey Albaugh
    Center for Urology, Northwestern Memorial Hospital, Chicago, IL, USA
    Urol Nurs 22:217-31; quiz 232. 2002
    ..If successful, this new model will allow quality sexual health care to be provided to increasing numbers of patients and their partners...
  47. ncbi Sexual dysfunction: looking beyond the obvious
    Irwin Goldstein
    J Sex Med 5:1-3. 2008
  48. ncbi Biochemical and functional characterization of alpha-adrenergic receptors in the rabbit vagina
    Noel N Kim
    Department of Urology, School of Medicine, Boston University, 700 Albany St W607, Boston, MA 02118, USA
    Life Sci 71:2909-20. 2002
    ..Thus, vaginal tissue expresses functional alpha-1 and alpha-2 AR, which modulate vaginal smooth muscle contractility and genital engorgement...
  49. ncbi The Journal of Sexual Medicine through ritual and spontaneity
    Irwin Goldstein
    J Sex Med 4:1523-5. 2007
  50. ncbi Role of androgens in female genital sexual arousal: receptor expression, structure, and function
    Abdulmaged M Traish
    Department of Biochemistry, Boston University School of Medicine, Massachusetts, Boston 02118, USA
    Fertil Steril 77:S11-8. 2002
    ..In this article, we review the mechanisms of androgen action and discuss new data on the effects of androgens in vaginal and clitoral tissues...
  51. ncbi Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment
    Gloria Bachmann
    Robert Wood Johnson Medical School, Women's Health Institute, New Jersey, New Brunswick, USA
    Fertil Steril 77:660-5. 2002
    ..A simplified management algorithm for women with low androgen in the presence of clinical symptoms and normal estrogen status has also been proposed...
  52. ncbi Postmenopausal female sexual dysfunction: at a crossroads
    Lorraine Dennerstein
    J Sex Med 2:116-7. 2005
  53. ncbi Epidemiological characteristics of 250 women with sexual dysfunction who presented for initial evaluation
    Lily Talakoub
    Center for Sexual Medicine, Department of Urology, Boston University School of Medicine, Boston, Massachusetts, USA
    J Sex Marital Ther 28:217-24. 2002
    ..More research in the management of women with sexual health problems is needed...
  54. ncbi The prevalence of phimosis of the clitoris in women presenting to the sexual dysfunction clinic: lack of correlation to disorders of desire, arousal and orgasm
    Ricardo Munarriz
    Center for Sexual Medicine, Department of Urology, Boston University School of Medicine, Boston, Massachusetts, USA
    J Sex Marital Ther 28:181-5. 2002
    ..Other than its link to sexual pain, the clinical significance of this finding, in particular the relation to diminished sensitivity and impaired orgasmic capability, is unclear at this time...
  55. ncbi Characteristics of female patients with sexual dysfunction who also had a history of blunt perineal trauma
    Ricardo Munarriz
    Center for Sexual Medicine, Department of Urology, Boston University School of Medicine, Boston, Massachusetts, USA
    J Sex Marital Ther 28:175-9. 2002
    ..A neurogenic form of sexual dysfunction has been implicated, with primary complaints of orgasm disorder and abnormalities noted on genital sensory testing. Further research in this area is needed...
  56. ncbi Regarding Waldinger and Schweitzer's "premature ejaculation and pharmaceutical company-based medicine: the dapoxetine case"
    Irwin Goldstein
    J Sex Med 5:965. 2008
  57. ncbi Effects of ovariectomy and estrogen and androgen treatment on sildenafil-mediated changes in female genital blood flow and vaginal lubrication in the animal model
    Kweonsik Min
    Department of Biochemistry, Boston University School of Medicine, Mass, USA
    Am J Obstet Gynecol 187:1370-6. 2002
    ..CONCLUSION: This study suggests that estradiol but not testosterone modulates genital hemodynamics and that sildenafil enhances genital blood flow irrespective of hormonal status...
  58. ncbi Flying without a plane: accomplishments of the Journal of Sexual Medicine on its third birthday
    Irwin Goldstein
    J Sex Med 4:827-9. 2007
  59. ncbi Biology of female sexual function
    Ricardo Munarriz
    Department of Urology, Boston University School of Medicine, 720 Harrison Avenue, Suite 606, Boston, MA 02118, USA
    Urol Clin North Am 29:685-93. 2002
    ....
  60. ncbi Bicycle riding and erectile dysfunction: an increase in interest (and concern)
    Vincent Huang
    Institute for Sexual Medicine, Department of Urology, Boston University School of Medicine, 720 Harrison Avenue, Boston, MA 02118, USA
    J Sex Med 2:596-604. 2005
    ..Straddling bicycle saddles with a nose extension is associated with suprasystolic perineal compression pressures, temporarily occluding penile perfusion and potentially inducing endothelial injury and vasculogenic ED...
  61. ncbi Only the nose knows: penile hemodynamic study of the perineum-saddle interface in men with erectile dysfunction utilizing bicycle saddles and seats with and without nose extensions
    Ricardo Munarriz
    Institute for Sexual Medicine, Department of Urology, Boston University School of Medicine, 720 Harrison Avenue, Suite 600, Boston, MA 02118, USA
    J Sex Med 2:612-9. 2005
    ..To investigate the differential impact of straddles (A(ns) and B(ns)) and noseless two-cheek seats (A(ntcs) and B(ntcs)) on penile hemodynamics and perineal compressive forces in subjects who cycle in a stationary bicycle...
  62. ncbi Physiology of female sexual function: animal models
    Annamaria Giraldi
    Rigshospitalet, Copenhagen, Denmark
    J Sex Med 1:237-53. 2004
    ..Serotonin and dopamine may modulate UG reflex activity. CONCLUSIONS: More research is needed in animal models in the physiology of female sexual function...
  63. ncbi Modulation of rat vaginal blood flow and estrogen receptor by estradiol
    Soo Woong Kim
    Department of Urology, Seoul National University College of Medicine, Seoul, Korea
    J Urol 172:1538-43. 2004
    ..These changes were paralleled by ERalpha protein levels. CONCLUSIONS: Estradiol is crucial for maintaining optimal vaginal blood flow in the rat. Lower levels of plasma estradiol trigger compensatory ERalpha up-regulation...
  64. ncbi The power of the written word
    Irwin Goldstein
    J Sex Med 3:379-81. 2006
  65. ncbi The role of sex steroid hormones in female sexual function and dysfunction
    Irwin Goldstein
    Institute for Sexual Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Clin Obstet Gynecol 47:471-84. 2004
  66. ncbi Differential regulation of the expression of estrogen, progesterone, and androgen receptors by sex steroid hormones in the vagina: immunohistochemical studies
    Monica A Pessina
    Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    J Sex Med 3:804-14. 2006
    ..CONCLUSION: Estradiol down-regulated ERalpha and up-regulated PR expression in the vagina, suggesting this may be a mechanism to prevent continued proliferation of the epithelium by surges of estradiol during the estrous cycle...
  67. ncbi Prevention and treatment of erectile dysfunction using lifestyle changes and dietary supplements: what works and what is worthless, part II
    Mark A Moyad
    Department of Urology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0330, USA
    Urol Clin North Am 31:259-73. 2004
    ..The coming years of research should bring enormous excitement and objectivity to this area of medicine...
  68. ncbi Successful use of electroconvulsive therapy in 2 cases of persistent sexual arousal syndrome and bipolar disorder
    Sergio A Yero
    Department of Psychiatry, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ 07103, USA
    J ECT 22:274-5. 2006
    ..They have remained on maintenance ECT with good results. Although the etiology of PSAS is unknown and its relationship to bipolar disorder is unclear, the successful resolution of PSAS with ECT is of clinical and theoretical interest...
  69. ncbi The Journal of Sexual Medicine in 2007: the electronic age
    Irwin Goldstein
    J Sex Med 4:1-3. 2007
  70. ncbi Binding characteristics of [3H]delta(5)-androstene-3beta,17beta-diol to a nuclear protein in the rabbit vagina
    Abdulmaged M Traish
    Department of Biochemistry, Boston University School of Medicine, 700 Albany Street, Room W607, Boston, MA 02118, USA
    Steroids 69:71-8. 2004
    ..These data suggest that rabbit vaginal tissue expresses a novel binding protein which specifically binds delta(5)-androstene-3beta,17beta-diol and is distinct from the androgen and estrogen receptors...
  71. ncbi Female sexuality and sexual dysfunction
    Irwin Goldstein
    Arch Sex Behav 31:391. 2002
  72. ncbi Penile revascularization for treatment of erectile dysfunction secondary to blunt perineal trauma
    Ricardo M Munarriz
    Department of Urology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Urology 61:222-3. 2003
  73. ncbi Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference)
    John B Kostis
    University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Am J Cardiol 96:85M-93M. 2005
    ..Finally, further research on the role of PDE-5 inhibition in treating patients with other medical or cardiovascular disorders is recommended...