Research Topics
| Matthew Bidwell GoetzSummaryCountry: USA Publications
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Publications
A system-wide intervention to improve HIV testing in the Veterans Health AdministrationMatthew Bidwell Goetz
Infectious Diseases Section 111 F, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
J Gen Intern Med 23:1200-7. 2008..Although the benefits of identifying and treating asymptomatic HIV-infected individuals are firmly established, health care providers often miss opportunities to offer HIV-testing...
Exportability of an intervention to increase HIV testing in the Veterans Health AdministrationMatthew Bidwell Goetz
VA Greater Los Angeles Healthcare System, Los Angeles, USA
Jt Comm J Qual Patient Saf 37:553-9. 2011..Exportability, or the dissemination of successful health services interventions from one site to another, must be demonstrated before systemwide implementation...- Evaluation of the sustainability of an intervention to increase HIV testingMatthew Bidwell Goetz
Infectious Diseases Section 111 F, VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA
J Gen Intern Med 24:1275-80. 2009..Sustainability-the routinization and institutionalization of processes that improve the quality of healthcare-is difficult to achieve and not often studied... - Relationship between HIV coreceptor tropism and disease progression in persons with untreated chronic HIV infectionMatthew Bidwell Goetz
Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
J Acquir Immune Defic Syndr 50:259-66. 2009..To assess the effect of HIV coreceptor tropism (CRT) on the relative risk of progression to a composite outcome of CD4 count < or =350 cells per microliter, treatment initiation, or death... - HIV replication capacity is an independent predictor of disease progression in persons with untreated chronic HIV infectionMatthew Bidwell Goetz
Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System and David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
J Acquir Immune Defic Syndr 53:472-9. 2010..To assess the effect of pol replication capacity (RC) on the hazard ratio of progression to a composite endpoint of time to progression to <350 CD4+ cells per microliter, initiation of therapy, or death... - Evolution of HIV resistance mutations in patients maintained on a stable treatment regimen after virologic failureMatthew Bidwell Goetz
Section of Infectious Diseases, Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
J Acquir Immune Defic Syndr 43:541-9. 2006.... - Evaluation of human immunodeficiency virus and hepatitis C telemedicine clinicsHemen N Saifu
Department of Medicine, VA Greater Los Angeles Health, Los Angeles, CA 90073, USA
Am J Manag Care 18:207-12. 2012..We assess the impact of human immunodeficiency virus (HIV) and hepatitis C telemedicine consultation on patient-oriented outcomes in a rural Veterans Affairs population... - The impact of integrated HIV care on patient health outcomesTuyen Hoang
Health Services Research and Development Center of Excellence, Veterans Affairs Greater Los Angeles Healthcare System, Sepulveda, CA, USA
Med Care 47:560-7. 2009..Yet many HIV-infected patients have comorbidities that pose social and clinical barriers to achieving viral suppression. Integration of subspecialty services into HIV primary care may overcome such barriers... 
Human immunodeficiency virus in an aging population, a complication of successJason B Kirk
Department of Medicine, Infectious Diseases Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA
J Am Geriatr Soc 57:2129-38. 2009..Nevertheless, older patients derive substantial benefit from combination antiretroviral therapy despite having less of an immunological response than expected given their adherence to therapy and excellent virological responses...- Improving HIV screening and receipt of results by nurse-initiated streamlined counseling and rapid testingHenry D Anaya
Center for the Study of Healthcare Provider Behavior, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
J Gen Intern Med 23:800-7. 2008..HIV rapid testing is effective in many healthcare settings, but scant research has been done within primary care settings or within the US Department of Veteran's Affairs Healthcare System... - Adherence, virological and immunological outcomes for HIV-infected veterans starting combination antiretroviral therapiesR Scott Braithwaite
Section of General Internal Medicine, Department of Medicine, Yale University, 950 Campbell Avenue, West Haven, CT 06516, USA
AIDS 21:1579-89. 2007..We aimed to determine adherence, virological, and immunological outcomes one year after starting a first combination antiretroviral therapy (ART) regimen... - Risk of heart failure with human immunodeficiency virus in the absence of prior diagnosis of coronary heart diseaseAdeel A Butt
Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Arch Intern Med 171:737-43. 2011..Whether human immunodeficiency virus (HIV) infection is a risk factor for heart failure (HF) is not clear. The presence of coronary heart disease and alcohol consumption in this population may confound this association... - Impact of a kiosk educational module on HIV screening rates and patient knowledgeHemen N Saifu
Department of Medicine, VA Greater Los Angeles Health System, California, USA
J Telemed Telecare 17:446-50. 2011..3; 95% CI: 036-2.1). The brief kiosk educational module did not improve HIV screening rates, but it increased overall patient knowledge about HIV testing... - Decreased serum antibody responses to recombinant pneumocystis antigens in HIV-infected and uninfected current smokersKristina Crothers
University of Washington School of Medicine, Department of Medicine, Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, 325 Ninth Avenue, Box 359762, Seattle, WA 98104, USA
Clin Vaccine Immunol 18:380-6. 2011..Whether smoking exerts an immunosuppressive effect that affects the P. jirovecii antibody response, colonization, or subsequent risk for disease is unclear; prospective, longitudinal studies are needed to evaluate these findings further... - A provider participatory implementation model for HIV testing in an EDJennifer C Chen
Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
Am J Emerg Med 29:418-26. 2011..The Centers for Disease Control and Prevention recommends routine HIV screening for adults... - Effect of an education kiosk on patient knowledge about rapid HIV screeningBenjamin C Sun
Department of Medicine, VA Greater Los Angeles Health System, California, USA
J Telemed Telecare 16:158-61. 2010..The majority of patients expressed excellent (38%) or very good (39%) satisfaction with the kiosk module. The results suggest that a computer kiosk can deliver brief and targeted education to improve knowledge about HIV screening... - Impact of clinical guidelines in the management of severe hospital-acquired pneumoniaGuy W Soo Hoo
Pulmonary and Critical Care Section 111Q, West Los Angeles Healthcare Center, VA Greater Los Angeles Healthcare System, Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90073, USA
Chest 128:2778-87. 2005..To asses the impact of locally developed antimicrobial treatment guidelines in the initial empiric treatment of ICU patients with severe hospital-acquired pneumonia (HAP)... - Do benefits of earlier antiretroviral treatment initiation outweigh harms for individuals at risk for poor adherence?R Scott Braithwaite
Department of Medicine, Section of General Internal Medicine, Yale University, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, USA
Clin Infect Dis 48:822-6. 2009..Earlier treatment increased life expectancy across a wide adherence range (50%-100% of doses taken). Delaying treatment for patients with suboptimal adherence may not always be appropriate... - Unhealthy alcohol and illicit drug use are associated with decreased quality of HIV careP Todd Korthuis
Department of Medicine, Oregon Health and Science University, Portland, OR 97239 3098, USA
J Acquir Immune Defic Syndr 61:171-8. 2012..HIV-infected patients with substance use experience suboptimal health outcomes, possibly because of variations in care... - Complications of HIV infection in an ageing population: challenges in managing older patients on long-term combination antiretroviral therapyHui Zhao
Cedars Sinai Medical Center, Los Angeles, CA, USA
J Antimicrob Chemother 66:1210-4. 2011..Based on these considerations guidelines for the treatment of HIV-infected patients state that increased age is a consideration in initiating antiretroviral therapy in persons with >350-500 CD4+ cells/mm³... - HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy eraKristina Crothers
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington School of Medicine, Harborview Medical Center, Seattle, WA 98104, USA
Am J Respir Crit Care Med 183:388-95. 2011..In aging HIV-infected populations comorbid diseases are important determinants of morbidity and mortality. Pulmonary diseases have not been systematically assessed in the combination antiretroviral therapy (ART) era... - Utilization and access to antiretroviral genotypic resistance testing and results within the US Department of Veterans AffairsMatthew Bidwell Goetz
Infectious Diseases Section, Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
J Acquir Immune Defic Syndr 41:59-62. 2006..We sought to characterize variation in the use of HIV genotypic resistance tests and how results were reported... - Impact of pneumococcal vaccination on the incidence of pneumonia by HIV infection status among patients enrolled in the Veterans Aging Cohort 5-Site StudyMaria C Rodriguez-Barradas
Medical Service, Michael E De Bakey Veterans Affairs VA Medical Center and Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
Clin Infect Dis 46:1093-100. 2008..Benefits of vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPV) among these patients continue to be debated... - Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision modelR Scott Braithwaite
Yale University and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut 06516, USA
Ann Intern Med 148:178-85. 2008..The optimal threshold for initiating HIV treatment is unclear... - Increasing prevalence of HCC and cirrhosis in patients with chronic hepatitis C virus infectionFasiha Kanwal
Department of Gastroenterology and Hepatology, John Cochran VA Medical Center, Saint Louis University, St Louis, Missouri, USA
Gastroenterology 140:1182-1188.e1. 2011..We examined time trends in the prevalence of cirrhosis and its related complications, such as hepatic decompensation and hepatocellular carcinoma (HCC)... - A budget impact analysis of rapid human immunodeficiency virus screening in Veterans Administration emergency departmentsRisha Gidwani
QUERI HIV HEPATITIS C, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA
J Emerg Med 42:719-26. 2012..Human immunodeficiency virus (HIV) screening is cost-effective and recommended in populations with low disease prevalence. However, because screening is not cost-saving, its financial feasibility must be understood... - Association between protease inhibitor use and increased cardiovascular risk in patients infected with human immunodeficiency virus: a systematic reviewDavid C Rhew
Veterans Affairs Greater Los Angeles Healthcare System, Division of Infectious Diseases, Los Angeles, California, USA
Clin Infect Dis 37:959-72. 2003..The benefits of the currently available PIs should be balanced against the long-term risk of cardiovascular disease... - Elevated vancomycin trough is not associated with nephrotoxicity among inpatient veteransKavitha K Prabaker
Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
J Hosp Med 7:91-7. 2012..OBJECTIVE/SETTING: We sought to determine if there was an association between vancomycin trough and nephrotoxicity, defined as 0.5 mg/L or 50% increase in serum creatinine, at a large Veterans Affairs medical center... - Viral load response to a pneumococcal conjugate vaccine, polysaccharide vaccine or placebo among HIV-infected patientsMatthew Bidwell Goetz
VA Greater Los Angeles Healthcare System and University of California Los Angeles, Los Angeles, CA, USA
AIDS 16:1421-3. 2002..Mean baseline viral load and CD4 cell count were 3.41 copies/ml (log10) and 457 cells/microl, respectively. We found no change in viral load during 24 weeks of follow-up for any vaccine or combination of vaccines or placebo... - Azithromycin monotherapy for patients hospitalized with community-acquired pneumonia: a 31/2-year experience from a veterans affairs hospitalRandy B Feldman
Division of Infectious Diseases, the VA Greater Los Angeles Healthcare System, Los Angeles, California, USA
Arch Intern Med 163:1718-26. 2003..CONCLUSION: Azithromycin monotherapy is equally as efficacious as other ATS-recommended regimens for treating hospitalized patients with mild-to-moderate community-acquired pneumonia... - Lipid screening in HIV-infected veteransP Todd Korthuis
Oregon Health and Sciences University, Portland 97239 3098, USA
J Acquir Immune Defic Syndr 35:253-60. 2004..Lipid screening is recommended for patients taking protease inhibitors (PIs)... - Pharmacokinetics and tolerability of oseltamivir combined with probenecidMark Holodniy
US Department of Veterans Affairs, Office of Public Health and Environmental Hazards, Washington, DC, USA
Antimicrob Agents Chemother 52:3013-21. 2008..012). Alternate-day dosing of oseltamivir plus dosing with probenecid four times daily achieved trough oseltamivir carboxylate concentrations adequate for neuraminidase inhibition in vitro, and this combination should be studied further... - Early switch and early discharge opportunities in intravenous vancomycin treatment of suspected methicillin-resistant staphylococcal species infectionsStephen Parodi
J Manag Care Pharm 9:317-26. 2003..KEYWORDS: Oxazolidanone, Vancomycin, Length of stay, Methicillin resistance, Staphylococcal infections..