Affiliation: GlaxoSmithKline Research and Development
Su X, Leon L, Laping N. Role of spinal Cav2.2 and Cav2.1 ion channels in bladder nociception. J Urol. 2008;179:2464-9 pubmed publisher
..However, agatoxin and verapamil were less effective. The study suggests that spinal Cav2.2 and Q-type Cav2.1 calcium channels contribute to acute bladder nociception, while Cav1 channels have a limited role. ..
Su X, Lashinger E, Leon L, HOFFMAN B, Hieble J, Gardner S, et al. An excitatory role for peripheral EP3 receptors in bladder afferent function. Am J Physiol Renal Physiol. 2008;295:F585-94 pubmed publisher
..EP3 receptors are involved in the regulation of bladder micturition and bladder nociception at the peripheral level. ..