Research Topics
| Robertino MeraSummaryAffiliation: GlaxoSmithKline Research and Development Country: USA Publications
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Detail Information
Publications
Increasing role of Staphylococcus aureus and community-acquired methicillin-resistant Staphylococcus aureus infections in the United States: a 10-year trend of replacement and expansionRobertino M Mera
Research Statistics Unit, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA
Microb Drug Resist 17:321-8. 2011..There is the need to properly characterize the temporal trend of U.S. Staphylococcus aureus infections, including methicillin-resistant S. aureus (MRSA) and community-acquired (CA) MRSA in inpatient and outpatient settings...
Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States over a 10-year period: Alexander ProjectRobertino M Mera
GlaxoSmithKline, Biomedical Data Sciences, Research Triangle Park, NC 27709 3398, USA
Diagn Microbiol Infect Dis 51:195-200. 2005..Three of four PEN-R isolates are also multiresistant. The rate of growth of multidrug resistance is higher than that of single antibiotic resistance...
Antibacterial use and Streptococcus pneumoniae penicillin resistance: A temporal relationship modelRobertino M Mera
Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Microb Drug Resist 12:158-63. 2006..There is a peak level of penicillin resistance associated with cumulative exposure to a combination of antibiotic classes that is unique for every country...
Impact of new Clinical Laboratory Standards Institute Streptococcus pneumoniae penicillin susceptibility testing breakpoints on reported resistance changes over timeRobertino M Mera
Research Statistics Unit, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA
Microb Drug Resist 17:47-52. 2011..12-0.5 increase, which may signal the loss of resistant vaccine serotypes and the acquisition of resistance by nonvaccine serotypes...
Serotype replacement and multiple resistance in Streptococcus pneumoniae after the introduction of the conjugate pneumococcal vaccineRobertino Mera
GlaxoSmithKline, Research Triangle Park, North Carolina, USA
Microb Drug Resist 14:101-7. 2008..S. pediatric population in 2005. Changes over time in serogroup prevalence and multidrug-resistance (MR) to antimicrobials were evaluated using the U.S. SENTRY surveillance program...
Acinetobacter baumannii 2002-2008: increase of carbapenem-associated multiclass resistance in the United StatesRobertino M Mera
Department of Research Statistics, GlaxoSmithKline, Durham, North Carolina 27709, USA
Microb Drug Resist 16:209-15. 2010..2%-47.0%). Over half of all A. baumannii-resistant isolates were carbapenem and multiclass resistant in 2008. Rates among subjects <18 years old have increased faster than those of the elderly, and in the ICU as compared to Ward...
The impact of the pneumococcal conjugate vaccine on antimicrobial resistance in the United States since 1996: evidence for a significant rebound by 2007 in many classes of antibioticsRobertino M Mera
GlaxoSmithKline, Research Triangle Park, Durham, North Carolina 27709, USA
Microb Drug Resist 15:261-8. 2009..The impact of the introduction of the pneumococcal conjugate vaccine over antimicrobial resistance has not been well established. The present study models the changes in resistance over time for all major classes of antibiotics...
Semi-automated risk estimation using large databases: quinolones and Clostridium difficile associated diarrheaRobertino M Mera
GlaxoSmithKline, Research Triangle Park, NC 27709, USA
Pharmacoepidemiol Drug Saf 19:610-7. 2010..A semi-automated method was used to investigate the effect of fluoroquinolones on the incidence of C. difficile associated diarrhea (CDAD)...
Predicting the future Streptococcus pneumoniae resistance landscapeRobertino Mera
Curr Opin Pharmacol 5:459-64. 2005..Moreover, understanding this temporal relationship allows us to predict that if the cumulative consumption stabilizes so will the resistance rates...
Temporal and spatial distribution of clonal complexes of Streptococcus pneumoniae isolates resistant to multiple classes of antibiotics in Belgium, 1997 to 2004Heather Amrine-Madsen
GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA
Antimicrob Agents Chemother 52:3216-20. 2008..1% to 6.6%. None of these changes can be attributed to PCV7 vaccine, as it was not in use in Belgium during the time period studied. There was evidence that MCNS clones flowed from West Flanders to Limburg...
Oropharyngeal candidiasis in HIV(+) patients may influence the selection of HIV-1 protease variantsPeter J Hickman
Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, 1901 Perdido Street, Box P6-1, New Orleans, LA 70112-1393, USA
Virus Res 87:97-106. 2002....
Risk factors for development of multiple-class resistance to Streptococcus pneumoniae Strains in Belgium over a 10-year period: antimicrobial consumption, population density, and geographic locationJohan Van Eldere
University Hospital Gasthuisberg, Leuven, Belgium
Antimicrob Agents Chemother 51:3491-7. 2007..Regional resistance rates are not linearly related to actual antibiotic use but are linked to past antibiotic use plus a combination of demographic and geographic factors...
