Arlene R Hughes

Summary

Affiliation: GlaxoSmithKline Research and Development
Country: USA

Publications

  1. ncbi request reprint Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations
    Arlene R Hughes
    GlaxoSmithKline, NC 27709, USA
    Pharmacogenomics 5:203-11. 2004
  2. ncbi request reprint Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
    Seth Hetherington
    HIV Clinical Development and Medical Affairs, GlaxoSmithKline, Research Triangle Park, NC 27709, USA
    Lancet 359:1121-2. 2002
  3. doi request reprint Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example
    Arlene R Hughes
    GlaxoSmithKline Genetics, 5 Moore Drive, PO Box 13398, Research Triangle Park, NC 27709, USA
    Pharmacogenomics 10:225-33. 2009

Collaborators

  • Allen D Roses
  • Clive Bowman
  • David J Dow
  • Seth Hetherington
  • Michael Mosteller
  • Michael Stocum
  • Abigail Handley
  • Mary E Fling
  • William Spreen
  • Kirstie Davies
  • Eric Lai
  • Denise Shortino
  • Linda M Thurmond
  • Katherine L Baker

Detail Information

Publications3

  1. ncbi request reprint Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations
    Arlene R Hughes
    GlaxoSmithKline, NC 27709, USA
    Pharmacogenomics 5:203-11. 2004
    ..Even after a marker set is identified, appropriate clinical identification and management of hypersensitivity to abacavir must remain the cornerstone of clinical practice...
  2. ncbi request reprint Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
    Seth Hetherington
    HIV Clinical Development and Medical Affairs, GlaxoSmithKline, Research Triangle Park, NC 27709, USA
    Lancet 359:1121-2. 2002
    ..Clinical monitoring and management of hypersensitivity reactions among patients receiving abacavir must remain unchanged...
  3. doi request reprint Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example
    Arlene R Hughes
    GlaxoSmithKline Genetics, 5 Moore Drive, PO Box 13398, Research Triangle Park, NC 27709, USA
    Pharmacogenomics 10:225-33. 2009
    ..Important lessons from this pharmacogenetics program will be discussed in this paper...