Research Topics
Species | Michael GoldSummaryAffiliation: GlaxoSmithKline Research and Development Country: USA Publications
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Detail Information
Publications
Study design factors and patient demographics and their effect on the decline of placebo-treated subjects in randomized clinical trials in Alzheimer's diseaseMichael Gold
GlaxoSmithKline, Research Triangle Park, NC 27709, USA
J Clin Psychiatry 68:430-8. 2007..To gain insight into factors affecting the rate of decline in placebo-treated subjects participating in Alzheimer's disease (AD) clinical trials...
Rosiglitazone monotherapy in mild-to-moderate Alzheimer's disease: results from a randomized, double-blind, placebo-controlled phase III studyMichael Gold
Neurosciences Medicines Development Center, GlaxoSmithKline, Stockley Park, Harlow, UK
Dement Geriatr Cogn Disord 30:131-46. 2010..An open-label extension study assessed the long-term safety and tolerability of 8 mg RSG XR...
Predictors of placebo response in pooled lamotrigine neuropathic pain clinical trialsMichael C Irizarry
WW Epidemiology, GlaxoSmithKline, Research Triangle Park, NC, USA
Clin J Pain 25:469-76. 2009..The 574 patients in the pooled lamotrigine treatment arms were used as a replication dataset...
SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled studyGareth Maher-Edwards
GlaxoSmithKline, Uxbridge, Middlesex, UK
Int J Geriatr Psychiatry 26:536-44. 2011..To estimate the treatment effects of SB-742457 and donepezil in Alzheimer disease (AD) in a contemporary clinical trial...
Rationale and design of a randomized controlled trial to assess the safety and efficacy of cardiac resynchronization therapy in patients with asymptomatic left ventricular dysfunction with previous symptoms or mild heart failure--the REsynchronization reVCecilia Linde
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
Am Heart J 151:288-94. 2006..The effects of CRT on HF outcomes in patients with asymptomatic left ventricular dysfunction (ALVD) or mild HF remain to be determined...
Galantamine prolonged-release formulation in the treatment of mild to moderate Alzheimer's diseaseHenry Brodaty
University of New South Wales, Sydney, Australia
Dement Geriatr Cogn Disord 20:120-32. 2005....
Clinical safety and efficacy studies of a novel formulation combining 1.2% clindamycin phosphate and 0.025% tretinoin for the treatment of acne vulgarisJoel Schlessinger
Advanced Skin Research Center, Omaha, NE, USA
J Drugs Dermatol 6:607-15. 2007..Individual ingredients and the combination were well-tolerated. Among those treated with the combination formulation, discontinuation rates due to adverse events were 1% or less...
Tau therapeutics for Alzheimer's disease: the promise and the challengesMichael Gold
Global Clinical Research and Development, CNS Analgesia, Johnson and Johnson Pharmaceutical Research and Development, Titusville, NJ 08560, USA
J Mol Neurosci 19:331-4. 2002..The issues discussed in this article are not exhaustively dealt with in either scope or detail...
Overview of the Alliance for Cellular SignalingAlfred G Gilman
Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Nature 420:703-6. 2002..One goal is to catalyse complementary research in individual laboratories; to facilitate this, all alliance data are freely available for use by the entire research community...
Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain BankWarren W Barker
Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami Beach, FL 33140, USA
Alzheimer Dis Assoc Disord 16:203-12. 2002..These estimates of the a priori probabilities of dementing disorders have implications for clinicians and researchers...
