- Recent advances in the discovery and evaluation of fatty acid amide hydrolase inhibitorsHongfeng Deng
GlaxoSmithKline, Platform Technology and Science Molecular Discovery Research, ELT Boston, 830 Winter Street, Waltham, MA 02451, USA
Expert Opin Drug Discov 5:961-93. 2010..With the entry of several compounds into clinical trials, FAAH inhibitor-based medicines are on the horizon...
- Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT)Hongfeng Deng
ELT Boston, Platform Technology and Science, GlaxoSmithKline, Waltham, Massachusetts, United States
J Med Chem 55:7061-79. 2012..This study provides the first small molecule evidence for the critical role of ADAMTS-5 in human cartilage degradation...