Todd C Appleby

Summary

Affiliation: Gilead Sciences
Country: USA

Publications

  1. pmc Visualizing ATP-dependent RNA translocation by the NS3 helicase from HCV
    Todd C Appleby
    Department of Structural Chemistry, Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA 94404, USA
    J Mol Biol 405:1139-53. 2011
  2. pmc Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase
    Martijn Fenaux
    Gilead Sciences, Foster City, California, USA
    Antimicrob Agents Chemother 57:804-10. 2013
  3. doi request reprint An adaptive mutation in NS2 is essential for efficient production of infectious 1b/2a chimeric hepatitis C virus in cell culture
    Katie Chan
    Gilead Sciences, Inc, Foster City, CA 94404, USA
    Virology 422:224-34. 2012

Collaborators

Detail Information

Publications3

  1. pmc Visualizing ATP-dependent RNA translocation by the NS3 helicase from HCV
    Todd C Appleby
    Department of Structural Chemistry, Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA 94404, USA
    J Mol Biol 405:1139-53. 2011
    ....
  2. pmc Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase
    Martijn Fenaux
    Gilead Sciences, Foster City, California, USA
    Antimicrob Agents Chemother 57:804-10. 2013
    ..This study has been registered at ClinicalTrials.gov under registration number NCT01431898.)...
  3. doi request reprint An adaptive mutation in NS2 is essential for efficient production of infectious 1b/2a chimeric hepatitis C virus in cell culture
    Katie Chan
    Gilead Sciences, Inc, Foster City, CA 94404, USA
    Virology 422:224-34. 2012
    ..Overall, the efficient production of infectious 1b/2a virus particles will facilitate the discovery and characterization of inhibitors targeting steps that involve the structural genes of genotype 1b HCV...