Mark W Gilbertson
- Smaller hippocampal volume predicts pathologic vulnerability to psychological traumaMark W Gilbertson
Research Service, Veterans Administration Medical Center, 718 Smyth Road, Manchester, New Hampshire 03104, USA
Nat Neurosci 5:1242-7. 2002..Furthermore, severe PTSD twin pairs-both the trauma-exposed and unexposed members-had significantly smaller hippocampi than non-PTSD pairs...
- Configural cue performance in identical twins discordant for posttraumatic stress disorder: theoretical implications for the role of hippocampal functionMark W Gilbertson
Manchester VA Medical Center, Manchester, New Hampshire 03104, USA
Biol Psychiatry 62:513-20. 2007..We test the hypothesis that hippocampus-based configural processing deficits are a pre-existing vulnerability factor for unremitting forms of PTSD...
- Neurocognitive function in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorderMark W Gilbertson
Research Service, Manchester VA Medical Center, NH 03104, USA
J Abnorm Psychol 115:484-95. 2006..The results support the notion that specific domains of cognitive function may serve as premorbid risk or protective factors in PTSD...
- Subtle neurologic compromise as a vulnerability factor for combat-related posttraumatic stress disorder: results of a twin studyTamara V Gurvits
Research Service, Veterans Affairs Medical Center, Manchester, NH, USA
Arch Gen Psychiatry 63:571-6. 2006..Previous studies have demonstrated subtle neurologic dysfunction in chronic posttraumatic stress disorder (PTSD) manifest as increased neurologic soft signs (NSSs). The origin of this dysfunction is undetermined...
- Effects of beta blockade, PTSD diagnosis, and explicit threat on the extinction and retention of an aversively conditioned responseScott P Orr
Department of Veterans Affairs Medical Center, Research Service 151, 718 Smyth Road, Manchester, NH 03104, United States
Biol Psychol 73:262-71. 2006..This suggests that belief in the presence of a threat is necessary and sufficient for activating a previously established CR...
- Is trauma a causal agent of psychopathologic symptoms in posttraumatic stress disorder? Findings from identical twins discordant for combat exposureMark W Gilbertson
Department of Research Service, Manchester VA Medical Center, 718 Smyth Rd, Manchester, NH 03104, USA
J Clin Psychiatry 71:1324-30. 2010..The current study tests this hypothesis...
- Volume of cerebellar vermis in monozygotic twins discordant for combat exposure: lack of relationship to post-traumatic stress disorderJames J Levitt
VA Boston Healthcare System, Clinical Neuroscience Division, Laboratory of Neuroscience, Brockton, MA 02301, USA
Psychiatry Res 148:143-9. 2006..Thus, the results do not support the structural abnormality of cerebellar vermis in combat-related PTSD...
- Cavum septum pellucidum in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorderFlavia S May
Department of Radiology, Brigham and Women s Hospital, Boston, Massachusetts, USA
Biol Psychiatry 55:656-8. 2004..Abnormally large cavum septum pellucidum has been reported in posttraumatic stress disorder; however, the origin of this association is uncertain...
- Evidence for acquired pregenual anterior cingulate gray matter loss from a twin study of combat-related posttraumatic stress disorderKiyoto Kasai
Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Biol Psychiatry 63:550-6. 2008..We employed a case-control design in monozygotic twin pairs discordant for combat exposure to address the preexisting versus acquired origin of brain morphometric abnormalities in PTSD...
- Clarifying the origin of biological abnormalities in PTSD through the study of identical twins discordant for combat exposureRoger K Pitman
Massachusetts General Hospital, Room 2616, Bldg 149, 13th St, Charlestown, MA 02129, USA
Ann N Y Acad Sci 1071:242-54. 2006..These results support the conclusion that the latter abnormalities represent antecedent, familial vulnerability factors for developing chronic PTSD upon exposure to a traumatic event...